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Search results 601 to 696 out of 696 for Mecom

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Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele  
Name: Mecom adjacent non-protein coding RNA; wild type
Allele Type: Not Specified
Protein
Organism: Mus musculus/domesticus
Length: 1232  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1042  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1051  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 994  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 52  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 606  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 843  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 949  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 949  
Fragment?: false
DO Term
Allele
Name: Mecom adjacent non-protein coding RNA; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
lncRNA Gene
Type: lncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: mouse, laboratory
ncRNA Gene
Type: ncRNA_gene
Organism: Mus pahari
ncRNA Gene
Type: ncRNA_gene
Organism: Mus spretus
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-10-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5805663
Age: postnatal week 7.6-14.1
Image: Dataset 2
Note: There was little or no staining observed.
Specimen Label: Dataset 2
Specimen Num: 1
Genotype
Symbol: Mannr/Mannr
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mannr/Mannr<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N
Zygosity: ht
Has Mutant Allele: true
Allele
Name: MDS1 and EVI1 complex locus; endonuclease-mediated mutation 1, Toshio Suda
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Allele
Name: MDS1 and EVI1 complex locus; targeted mutation 4, Archibald Perkins
Allele Type: Targeted
Attribute String: Inducible, Modified isoform(s), Recombinase
Publication
First Author: Goff LA
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain.
Volume: 112
Issue: 22
Pages: 6855-62
Allele
Name: MDS1 and EVI1 complex locus; targeted mutation 4.1, Archibald Perkins
Allele Type: Targeted
Attribute String: Inducible, Modified isoform(s), Recombinase
Strain
Attribute String: targeted mutation, congenic, mutant strain
Publication  
First Author: Sauvageau M
Year: 2013
Journal: Elife
Title: Multiple knockout mouse models reveal lincRNAs are required for life and brain development.
Volume: 2
Pages: e01749
Allele
Name: transgene insertion NG190, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: MDS1 and EVI1 complex locus; targeted mutation 1.1, Fernando D Camargo
Allele Type: Targeted
Attribute String: Conditional ready, Reporter
Publication
First Author: Lai KM
Year: 2015
Journal: PLoS One
Title: Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs.
Volume: 10
Issue: 4
Pages: e0125522
Allele
Name: runt related transcription factor 1; targeted mutation 2.1, Hiroaki Honda
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant stock, transgenic
Allele
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Toshio Suda
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 2, Toshio Suda
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence, Reporter
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Runx1/Runx1<+>
Background: B6.129P2-Runx1
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Mecom/Mecom<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Protein Domain
Type: Domain
Description: This entry represents the PR/SET domain found in PR domain zinc finger protein 3 (PRDM3, also known as MECOM or EVI-1). PRDM3 and PRDM16 share protein sequences similarities and have functions in hematopoietic and neuronal stem cells and in adipose tissue differentiation. They also act as oncoproteins (Mel1 and Evi1) involved in translocation-induced leukemia. PRDM3 and PRDM16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity [].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes [].
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Mecom/Mecom<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Cai SF
Year: 2020
Journal: Cancer Discov
Title: Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.
Volume: 10
Issue: 10
Pages: 1500-1513
Publication
First Author: Li BE
Year: 2013
Journal: Blood
Title: Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Volume: 122
Issue: 12
Pages: 2039-46
Publication
First Author: Fenouille N
Year: 2017
Journal: Nat Med
Title: The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Volume: 23
Issue: 3
Pages: 301-313
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Mecom/Mecom<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wu H
Year: 2013
Journal: Cell Rep
Title: Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
Volume: 5
Issue: 1
Pages: 13-20
Publication  
First Author: Casamassimi A
Year: 2020
Journal: Int J Mol Sci
Title: Multifaceted Role of PRDM Proteins in Human Cancer.
Volume: 21
Issue: 7
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112