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Search results 601 to 688 out of 688 for Mia

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Hits by Strain

Type Details Score
Strain
MGI:7853143 | C57BL/6NCrl-Mia3<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Mia3/Mia3
Background: involves: 129S5/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mia2/Mia2
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mia/Mia<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Publication
23298834 | J:194497
First Author: Voelkl J
Year: 2013
Journal: J Clin Invest
Title: Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice.
Volume: 123
Issue: 2
Pages: 812-22
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Publication
31241461 | J:279139
   
First Author: Cibi DM
Year: 2019
Journal: Elife
Title: Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate.
Volume: 8
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Protein Domain
IPR042801 | OTOR
Type: Family
Description: Otoraplin, also known as MIAL (MIA-like), is specifically expressed in the cochlea and the vestibule of the inner ear and may contribute to inner ear dysfunction in humans []. It is a member of the MIA family. MIA (melanoma inhibitory activity) family members include MIA, MIAL, MIA2, and MIA3 (also called TANGO). MIA was found to be strongly expressed and secreted by malignant melanomas. It contains a domain that adopts a Src Homology 3 (SH3) domain-like fold; however, it contains an additional antiparallel beta sheet and two disulfide bonds compared to classical SH3 domains. Unlike classical SH3 domains, MIA does not bind proline-rich ligands [, ].
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Protein Domain
IPR035554 | Otoraplin_SH3
Type: Domain
Description: Otoraplin, also known as MIAL (MIA-like), is specifically expressed in the cochlea and the vestibule of the inner ear and may contribute to inner ear dysfunction in humans []. It is a member of the MIA family. MIA (melanoma inhibitory activity) family members include MIA, MIAL, MIA2, and MIA3 (also called TANGO). MIA was found to be strongly expressed and secreted by malignant melanomas. It contains a domain that adopts a Src Homology 3 (SH3) domain-like fold; however, it contains an additional antiparallel beta sheet and two disulfide bonds compared to classical SH3 domains. Unlike classical SH3 domains, MIA does not bind proline-rich ligands [, ].
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Publication
36450710 | J:350067
First Author: Chen H
Year: 2022
Journal: Nat Commun
Title: The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis.
Volume: 13
Issue: 1
Pages: 7375
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Publication
27106803 | J:250833
 
First Author: Voelkl J
Year: 2016
Journal: J Mol Cell Cardiol
Title: AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes.
Volume: 97
Pages: 36-43
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Publication
19166853 | -
First Author: Pilet E
Year: 2009
Journal: FEBS Lett
Title: The role of the maturase HydG in [FeFe]-hydrogenase active site synthesis and assembly.
Volume: 583
Issue: 3
Pages: 506-11
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Publication
17969213 | -
First Author: Kriek M
Year: 2007
Journal: Angew Chem Int Ed Engl
Title: Thiamine biosynthesis in Escherichia coli: identification of the intermediate and by-product derived from tyrosine.
Volume: 46
Issue: 48
Pages: 9223-6
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Publication
17403671 | -
First Author: Kriek M
Year: 2007
Journal: J Biol Chem
Title: Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.
Volume: 282
Issue: 24
Pages: 17413-23
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Protein Domain
IPR034428 | ThiH/NoCL/HydG-like
Type: Family
Description: These proteins homolytically cleave the C-alpha--C-beta bond of aromatic amino acids (such as tyrosine in ThiH and HydG or tryptophan in the MIA synthase family) using the 5'-deoxyadenosyl radical formed by the Radical SAM enzymes [, , , ].
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Publication
18537677 | -
First Author: Stoll R
Year: 2008
Journal: Curr Protein Pept Sci
Title: Extracellular SH3 domain containing proteins--features of a new protein family.
Volume: 9
Issue: 3
Pages: 221-6
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Genotype
Genotype
Symbol: Mia2/Mia2 Speer6-ps1/Speer6-ps1<+>
Background: involves: 129 * C57BL/6 * DBA
Zygosity: cn
Has Mutant Allele: true
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Publication
21454624 | -
First Author: Zhang Q
Year: 2011
Journal: J Biol Chem
Title: Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme.
Volume: 286
Issue: 24
Pages: 21287-94
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Publication
12586826 | -
First Author: Bosserhoff AK
Year: 2003
Journal: J Biol Chem
Title: Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.
Volume: 278
Issue: 17
Pages: 15225-31
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Publication
17881540 | -
First Author: Hellerbrand C
Year: 2008
Journal: Gut
Title: The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.
Volume: 57
Issue: 2
Pages: 243-51
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Publication
15780062 | -
First Author: Hellerbrand C
Year: 2005
Journal: Liver Int
Title: In situ expression patterns of melanoma inhibitory activity 2 in healthy and diseased livers.
Volume: 25
Issue: 2
Pages: 357-66
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Protein Domain
IPR035555 | MIA2_SH3
Type: Domain
Description: MIA2 is expressed specifically in hepatocytes and its expression is controlled by hepatocyte nuclear factor 1 binding sites in the MIA2 promoter [, ]. It inhibits the growth and invasion of hepatocellular carcinomas (HCC) and may act as a tumour suppressor []. A mutation in MIA2 in mice resulted in reduced cholesterol and triglycerides. Since MIA2 localizes to ER exit sites, it may function as an ER-to-Golgi trafficking protein that regulates lipid metabolism []. MIA2 contains an N-terminal SH3-like domain, similar to MIA.MIA (melanoma inhibitory activity) family members include MIA, MIAL, MIA2, and MIA3 (also called TANGO). MIA was found to be strongly expressed and secreted by malignant melanomas. It contains a domain that adopts a Src Homology 3 (SH3) domain-like fold; however, it contains an additional antiparallel beta sheet and two disulfide bonds compared to classical SH3 domains. Unlike classical SH3 domains, MIA does not bind proline-rich ligands [, ].
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Protein
Q9JIE3
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Protein
Q548U4
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Publication
27838335 | J:319623
 
First Author: Wu WL
Year: 2017
Journal: Brain Behav Immun
Title: The placental interleukin-6 signaling controls fetal brain development and behavior.
Volume: 62
Pages: 11-23
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Publication
36417858 | J:332180
First Author: López DA
Year: 2022
Journal: Cell Rep
Title: Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity.
Volume: 41
Issue: 8
Pages: 111677
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Publication
33361822 | J:305864
First Author: Kalish BT
Year: 2021
Journal: Nat Neurosci
Title: Maternal immune activation in mice disrupts proteostasis in the fetal brain.
Volume: 24
Issue: 2
Pages: 204-213
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Publication
26822608 | J:229446
First Author: Choi GB
Year: 2016
Journal: Science
Title: The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring.
Volume: 351
Issue: 6276
Pages: 933-9
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Publication
31167129 | J:300336
First Author: Andoh M
Year: 2019
Journal: Cell Rep
Title: Exercise Reverses Behavioral and Synaptic Abnormalities after Maternal Inflammation.
Volume: 27
Issue: 10
Pages: 2817-2825.e5
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Publication
31365857 | J:280099
First Author: Thion MS
Year: 2019
Journal: Cell Rep
Title: Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits.
Volume: 28
Issue: 5
Pages: 1119-1126.e4
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Publication
28102228 | J:247581
First Author: Pendyala G
Year: 2017
Journal: Neuropsychopharmacology
Title: Maternal Immune Activation Causes Behavioral Impairments and Altered Cerebellar Cytokine and Synaptic Protein Expression.
Volume: 42
Issue: 7
Pages: 1435-1446
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Publication
35544642 | J:324465
First Author: Yu D
Year: 2022
Journal: Sci Adv
Title: Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits.
Volume: 8
Issue: 18
Pages: eabm2545
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Publication
17431427 | J:139292
First Author: Kasuno K
Year: 2007
Journal: Cell Death Differ
Title: Antagonism of p66shc by melanoma inhibitory activity.
Volume: 14
Issue: 8
Pages: 1414-21
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Publication
29967099 | J:264315
First Author: Lammert CR
Year: 2018
Journal: J Immunol
Title: Cutting Edge: Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism.
Volume: 201
Issue: 3
Pages: 845-850
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Publication
33067431 | J:296819
First Author: Tsivion-Visbord H
Year: 2020
Journal: Nat Commun
Title: Increased RNA editing in maternal immune activation model of neurodevelopmental disease.
Volume: 11
Issue: 1
Pages: 5236
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Publication
31740755 | J:308977
First Author: Ben-Reuven L
Year: 2021
Journal: Mol Psychiatry
Title: Dynamics of cortical progenitors and production of subcerebral neurons are altered in embryos of a maternal inflammation model for autism.
Volume: 26
Issue: 5
Pages: 1535-1550
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Publication
33953172 | J:317913
First Author: Liu Y
Year: 2021
Journal: Cell Death Dis
Title: Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.
Volume: 12
Issue: 5
Pages: 448
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Publication
25683697 | J:317553
 
First Author: Wu WL
Year: 2015
Journal: Brain Behav Immun
Title: The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring.
Volume: 46
Pages: 192-202
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Publication
36621763 | J:333476
 
First Author: Taylor AJ
Year: 2023
Journal: Mol Metab
Title: Islet amyloid polypeptide does not suppress pancreatic cancer.
Volume: 68
Pages: 101667
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Publication
35153665 | J:322039
 
First Author: Minnema L
Year: 2022
Journal: Front Neurosci
Title: Investigating the Role of Artemin and Its Cognate Receptor, GFRα3, in Osteoarthritis Pain.
Volume: 16
Pages: 738976
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Publication
25055824 | J:222074
First Author: Coaxum SD
Year: 2014
Journal: Am J Physiol Cell Physiol
Title: Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger.
Volume: 307
Issue: 6
Pages: C554-60
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Publication
27919787 | J:239396
 
First Author: Garg B
Year: 2017
Journal: Cancer Lett
Title: Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer.
Volume: 388
Pages: 64-72
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Publication
26830140 | J:359672
First Author: Canetta S
Year: 2016
Journal: Mol Psychiatry
Title: Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons.
Volume: 21
Issue: 7
Pages: 956-68
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Publication
26521748 | J:311645
First Author: Moilanen LJ
Year: 2015
Journal: Osteoarthritis Cartilage
Title: Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis.
Volume: 23
Issue: 11
Pages: 2017-26
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Publication
33310189 | J:305512
 
First Author: Zhang X
Year: 2021
Journal: Biochem Biophys Res Commun
Title: NOX1/NADPH oxidase affects the development of autism-like behaviors in a maternal immune activation model.
Volume: 534
Pages: 59-66
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Publication
23637159 | J:197023
First Author: Lipina TV
Year: 2013
Journal: J Neurosci
Title: Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice.
Volume: 33
Issue: 18
Pages: 7654-66
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Publication
31684073 | J:344693
 
First Author: Shin HJ
Year: 2019
Journal: J Clin Med
Title: Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis.
Volume: 8
Issue: 11
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Publication
39486137 | J:359117
 
First Author: Hasegawa M
Year: 2024
Journal: Biochem Biophys Res Commun
Title: Maternal immune activation induces neurodevelopmental impairments of adult offspring through alterations in tryptophane-kynurenine pathway in the placenta.
Volume: 737
Pages: 150922
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Publication
35617425 | J:331403
First Author: Laubach KN
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1.
Volume: 119
Issue: 22
Pages: e2123202119
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Publication
38775708 | J:349172
 
First Author: Ostrem BEL
Year: 2024
Journal: Development
Title: Fetal brain response to maternal inflammation requires microglia.
Volume: 151
Issue: 10
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Publication
33600830 | J:307699
 
First Author: Anderson A
Year: 2021
Journal: Brain Res
Title: Interaction of maternal immune activation and genetic interneuronal inhibition.
Volume: 1759
Pages: 147370
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Publication
31811906 | J:283706
 
First Author: Yue Y
Year: 2020
Journal: Cancer Lett
Title: 2'-Hydroxyflavanone inhibits the progression of pancreatic cancer cells and sensitizes the chemosensitivity of EGFR inhibitors via repressing STAT3 signaling.
Volume: 471
Pages: 135-146
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Publication
32431699 | J:308193
 
First Author: Na HS
Year: 2020
Journal: Front Immunol
Title: Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis.
Volume: 11
Pages: 730
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Publication
35377817 | J:344864
First Author: Zhao Q
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation.
Volume: 119
Issue: 15
Pages: e2113310119
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Publication
36343752 | J:331895
 
First Author: Zengeler KE
Year: 2022
Journal: Brain Behav Immun
Title: SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology.
Volume: 108
Pages: 80-97
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Publication
31853066 | J:289937
First Author: Reed MD
Year: 2020
Journal: Nature
Title: IL-17a promotes sociability in mouse models of neurodevelopmental disorders.
Volume: 577
Issue: 7789
Pages: 249-253
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Publication
35273483 | J:321969
 
First Author: Sandoval KC
Year: 2022
Journal: Front Behav Neurosci
Title: Lack of Vesicular Zinc Does Not Affect the Behavioral Phenotype of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation Mice.
Volume: 16
Pages: 769322
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Publication
30683682 | J:273863
First Author: Horváth G
Year: 2019
Journal: J Neurosci
Title: P2X7 Receptors Drive Poly(I:C) Induced Autism-like Behavior in Mice.
Volume: 39
Issue: 13
Pages: 2542-2561
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Publication
30617212 | J:272036
First Author: Xu X
Year: 2019
Journal: J Neurosci
Title: Transient Knock-Down of Prefrontal DISC1 in Immune-Challenged Mice Causes Abnormal Long-Range Coupling and Cognitive Dysfunction throughout Development.
Volume: 39
Issue: 7
Pages: 1222-1235
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Publication
33230114 | J:299860
First Author: Jin L
Year: 2020
Journal: Nat Commun
Title: STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.
Volume: 11
Issue: 1
Pages: 5941
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Publication
33127853 | J:297672
First Author: Chen HR
Year: 2020
Journal: J Neurosci
Title: Monocytic Infiltrates Contribute to Autistic-like Behaviors in a Two-Hit Model of Neurodevelopmental Defects.
Volume: 40
Issue: 49
Pages: 9386-9400
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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