| Type |
Details |
Score |
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1683328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850966 |
|
| Specimen Label: |
UC Davis_1850966 |
| Detected: |
true |
| Specimen Num: |
116 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1683328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850779 |
|
| Specimen Label: |
UC Davis_1850779 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1683328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850780 |
|
| Specimen Label: |
UC Davis_1850780 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1832122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1832128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850944 |
|
| Specimen Label: |
UC Davis_1850944 |
| Detected: |
true |
| Specimen Num: |
167 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1832128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850884 |
|
| Specimen Label: |
UC Davis_1850884 |
| Detected: |
true |
| Specimen Num: |
107 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1832128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850885 |
|
| Specimen Label: |
UC Davis_1850885 |
| Detected: |
true |
| Specimen Num: |
108 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
| Image: |
2Ab |
| Note: |
This expression is noted in addition to general staining in the central nervous system. |
| Specimen Label: |
2Ab |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1725219 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:3052021 |
| Age: |
embryonic day 11.5 |
| Image: |
2Aa |
| Note: |
Staining is interdigital. |
| Specimen Label: |
2Aa |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3599828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850934 |
|
| Specimen Label: |
UC Davis_1850934 |
| Detected: |
true |
| Specimen Num: |
157 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3599828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850837 |
|
| Specimen Label: |
UC Davis_1850837 |
| Detected: |
true |
| Specimen Num: |
64 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3599828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850838 |
|
| Specimen Label: |
UC Davis_1850838 |
| Detected: |
true |
| Specimen Num: |
65 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1885228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850937 |
|
| Specimen Label: |
UC Davis_1850937 |
| Detected: |
true |
| Specimen Num: |
160 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1885228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850796 |
|
| Specimen Label: |
UC Davis_1850796 |
| Detected: |
true |
| Specimen Num: |
23 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1885228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850797 |
|
| Specimen Label: |
UC Davis_1850797 |
| Detected: |
true |
| Specimen Num: |
24 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1724819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:3052021 |
| Age: |
embryonic day 11.5 |
| Image: |
2Aa |
| Note: |
Staining is interdigital. |
| Specimen Label: |
2Aa |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1857728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850826 |
|
| Specimen Label: |
UC Davis_1850826 |
| Detected: |
true |
| Specimen Num: |
53 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1857728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850827 |
|
| Specimen Label: |
UC Davis_1850827 |
| Detected: |
true |
| Specimen Num: |
54 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850931 |
|
| Specimen Label: |
UC Davis_1850931 |
| Detected: |
true |
| Specimen Num: |
155 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850856 |
|
| Specimen Label: |
UC Davis_1850856 |
| Detected: |
true |
| Specimen Num: |
83 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850857 |
|
| Specimen Label: |
UC Davis_1850857 |
| Detected: |
true |
| Specimen Num: |
84 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850858 |
|
| Specimen Label: |
UC Davis_1850858 |
| Detected: |
true |
| Specimen Num: |
85 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850909 |
|
| Specimen Label: |
UC Davis_1850909 |
| Detected: |
true |
| Specimen Num: |
138 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1752528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850910 |
|
| Specimen Label: |
UC Davis_1850910 |
| Detected: |
true |
| Specimen Num: |
139 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1802528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850951 |
| Note: |
chest bone |
| Specimen Label: |
UC Davis_1850951 |
| Detected: |
true |
| Specimen Num: |
173 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850936 |
|
| Specimen Label: |
UC Davis_1850936 |
| Detected: |
true |
| Specimen Num: |
159 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850792 |
|
| Specimen Label: |
UC Davis_1850792 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850793 |
|
| Specimen Label: |
UC Davis_1850793 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850794 |
|
| Specimen Label: |
UC Davis_1850794 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850795 |
|
| Specimen Label: |
UC Davis_1850795 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850948 |
|
| Specimen Label: |
UC Davis_1850948 |
| Detected: |
true |
| Specimen Num: |
171 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850915 |
|
| Specimen Label: |
UC Davis_1850915 |
| Detected: |
true |
| Specimen Num: |
142 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850916 |
|
| Specimen Label: |
UC Davis_1850916 |
| Detected: |
true |
| Specimen Num: |
143 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850917 |
|
| Specimen Label: |
UC Davis_1850917 |
| Detected: |
true |
| Specimen Num: |
144 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850939 |
|
| Specimen Label: |
UC Davis_1850939 |
| Detected: |
true |
| Specimen Num: |
162 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850800 |
|
| Specimen Label: |
UC Davis_1850800 |
| Detected: |
true |
| Specimen Num: |
27 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850801 |
|
| Specimen Label: |
UC Davis_1850801 |
| Detected: |
true |
| Specimen Num: |
28 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850802 |
|
| Specimen Label: |
UC Davis_1850802 |
| Detected: |
true |
| Specimen Num: |
29 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850897 |
|
| Specimen Label: |
UC Davis_1850897 |
| Detected: |
true |
| Specimen Num: |
126 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850898 |
|
| Specimen Label: |
UC Davis_1850898 |
| Detected: |
true |
| Specimen Num: |
127 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850899 |
|
| Specimen Label: |
UC Davis_1850899 |
| Detected: |
true |
| Specimen Num: |
128 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1915328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850968 |
|
| Specimen Label: |
UC Davis_1850968 |
| Detected: |
true |
| Specimen Num: |
118 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1915328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850848 |
|
| Specimen Label: |
UC Davis_1850848 |
| Detected: |
true |
| Specimen Num: |
75 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1915328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850849 |
|
| Specimen Label: |
UC Davis_1850849 |
| Detected: |
true |
| Specimen Num: |
76 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1915328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850850 |
|
| Specimen Label: |
UC Davis_1850850 |
| Detected: |
true |
| Specimen Num: |
77 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
| Image: |
2Ba |
| Note: |
Expression is in the neuroepithelium. |
| Specimen Label: |
2Ba |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
| Image: |
2Bb |
| Note: |
Expression is in the neuroepithelium. |
| Specimen Label: |
2Bb |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
| Image: |
2Be |
|
| Specimen Label: |
2Be |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850933 |
|
| Specimen Label: |
UC Davis_1850933 |
| Detected: |
true |
| Specimen Num: |
156 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850839 |
|
| Specimen Label: |
UC Davis_1850839 |
| Detected: |
true |
| Specimen Num: |
66 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850840 |
|
| Specimen Label: |
UC Davis_1850840 |
| Detected: |
true |
| Specimen Num: |
67 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850841 |
|
| Specimen Label: |
UC Davis_1850841 |
| Detected: |
true |
| Specimen Num: |
68 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850842 |
|
| Specimen Label: |
UC Davis_1850842 |
| Detected: |
true |
| Specimen Num: |
69 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1789622 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3051609 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2004-09-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3281222 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3052019 |
| Age: |
embryonic day 14.5 |
| Image: |
2Bh |
|
| Specimen Label: |
2Bh |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3281228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850972 |
|
| Specimen Label: |
UC Davis_1850972 |
| Detected: |
true |
| Specimen Num: |
122 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2991528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850971 |
|
| Specimen Label: |
UC Davis_1850971 |
| Detected: |
true |
| Specimen Num: |
121 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2991528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850879 |
|
| Specimen Label: |
UC Davis_1850879 |
| Detected: |
true |
| Specimen Num: |
102 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2991528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850880 |
|
| Specimen Label: |
UC Davis_1850880 |
| Detected: |
true |
| Specimen Num: |
103 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2991528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850881 |
|
| Specimen Label: |
UC Davis_1850881 |
| Detected: |
true |
| Specimen Num: |
104 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850927 |
|
| Specimen Label: |
UC Davis_1850927 |
| Detected: |
true |
| Specimen Num: |
151 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850969 |
|
| Specimen Label: |
UC Davis_1850969 |
| Detected: |
true |
| Specimen Num: |
119 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850873 |
|
| Specimen Label: |
UC Davis_1850873 |
| Detected: |
true |
| Specimen Num: |
96 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850874 |
|
| Specimen Label: |
UC Davis_1850874 |
| Detected: |
true |
| Specimen Num: |
97 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850875 |
|
| Specimen Label: |
UC Davis_1850875 |
| Detected: |
true |
| Specimen Num: |
98 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850876 |
|
| Specimen Label: |
UC Davis_1850876 |
| Detected: |
true |
| Specimen Num: |
99 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1881228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850770 |
|
| Specimen Label: |
UC Davis_1850770 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1881228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850771 |
|
| Specimen Label: |
UC Davis_1850771 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1881228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850772 |
|
| Specimen Label: |
UC Davis_1850772 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1881228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691789 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1850773 |
|
| Specimen Label: |
UC Davis_1850773 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mid1ip1/Mid1ip1<+> |
| Background: |
C57BL/6N-Mid1ip1/Ucd |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mid1/? |
| Background: |
B6.Cg-Mid1 |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim CW |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis. |
| Volume: |
107 |
| Issue: |
21 |
| Pages: |
9626-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Colbert CL |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Crystal structure of Spot 14, a modulator of fatty acid synthesis. |
| Volume: |
107 |
| Issue: |
44 |
| Pages: |
18820-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsatsos NG |
| Year: |
2008 |
| Journal: |
Endocrinology |
| Title: |
Hepatic expression of the SPOT 14 (S14) paralog S14-related (Mid1 interacting protein) is regulated by dietary carbohydrate. |
| Volume: |
149 |
| Issue: |
10 |
| Pages: |
5155-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park S |
| Year: |
2013 |
| Journal: |
J Mol Recognit |
| Title: |
Spot14/Mig12 heterocomplex sequesters polymerization and restrains catalytic function of human acetyl-CoA carboxylase 2. |
| Volume: |
26 |
| Issue: |
12 |
| Pages: |
679-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aipoalani DL |
| Year: |
2010 |
| Journal: |
Endocrinology |
| Title: |
Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis. |
| Volume: |
151 |
| Issue: |
5 |
| Pages: |
2071-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wright KM |
| Year: |
2016 |
| Journal: |
FEBS J |
| Title: |
Solution structure of the microtubule-targeting COS domain of MID1. |
| Volume: |
283 |
| Issue: |
16 |
| Pages: |
3089-102 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the COS domain found in the C-I subfamily of the tripartite motif (TRIM) family of E3 ubiquitin ligases.The C-1 subfamily includes MID1 (TRIM18), MID2 (TRIM1), TRIM9, TNL (TRIM67), TRIM36 and TRIFIC (TRIM46) [, , ]. The C-I subfamily contains C-terminal FNIII and B30.2 domains which are associated with microtubules [, ]. C-I subfamily members also contain a relatively conserved region of approximately 60 amino acids, termed the C-terminal subgroup One Signature (COS) domain []. The human Midline-1 (MID1) COS domain has a helix-loop-helix structure in which the N- and C-terminal ends are in close proximity []. Deletion of the human MID1 COS domain does not affect MID1 dimerisation but disrupts localisation to the microtubules [].The COS domain is also observed within the TRIM C-II subgroup, which consists of the MURF1-3 proteins that do not contain the FNIII and B30.2domains. MUF1-3 proteins are also associated with microtubules []. |
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| Publication |
| First Author: |
Ozeki-Miyawaki C |
| Year: |
2005 |
| Journal: |
Exp Cell Res |
| Title: |
Identification of functional domains of Mid1, a stretch-activated channel component, necessary for localization to the plasma membrane and Ca2+ permeation. |
| Volume: |
311 |
| Issue: |
1 |
| Pages: |
84-95 |
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| Publication |
| First Author: |
Maruoka T |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Essential hydrophilic carboxyl-terminal regions including cysteine residues of the yeast stretch-activated calcium-permeable channel Mid1. |
| Volume: |
277 |
| Issue: |
14 |
| Pages: |
11645-52 |
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| Publication |
| First Author: |
Carnero E |
| Year: |
2000 |
| Journal: |
Mol Gen Genet |
| Title: |
Schizosaccharomyces pombe ehs1p is involved in maintaining cell wall integrity and in calcium uptake. |
| Volume: |
264 |
| Issue: |
1-2 |
| Pages: |
173-83 |
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| Publication |
| First Author: |
Geetha TS |
| Year: |
2014 |
| Journal: |
Hum Mutat |
| Title: |
Targeted deep resequencing identifies MID2 mutation for X-linked intellectual disability with varied disease severity in a large kindred from India. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
41-4 |
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| Protein Domain |
| Type: |
Family |
| Description: |
In Saccharomyces cerevisiae, Mid1 is a yeast plasma membrane protein required for Ca2+ influx induced by the mating pheromone alpha-factor during the mating process [, , ]. The protein is composed of 548-amino-acid residues, contains four hydrophobic regions (H1, H2, H3 and H4) and two cysteine-rich regions (C1 and C2) at the C terminus. H1 appears to be a signal sequence necessary for the alpha-factor-induced delivery to the plasma membrane. The region from H1 to H3 is required for the localisation of Mid1 in the plasma and ER membranes. C1 and C2 are thought to be involved in oligomerisation via the formation of disulphide bonds. Trafficking of Mid1-GFP to the plasma membrane is dependent on the N-glycosylation of Mid1 and the transporter protein Sec12. This suggests that the trafficking of Mid1-GFP to the plasma membrane requires a Sec12-dependent pathway from the ER to the Golgi, and that Mid1 is recruited via a Sec6- and Sec7-independent pathway from the Golgi to the plasma membrane.This entry also includes Ehs1 from Schizosaccharomyces pombe. Ehs1 is required for Ca2+ influx and for vitality of cells in a late, pheromone-induced event of the mating process requiring calcium-induced signaling []. |
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| Protein Domain |
| Type: |
Family |
| Description: |
MID2 shares high structural and functional similarities with MID1, an ubiquitin E3 ligase that regulates the turnover of microtubular protein phosphatase 2Ac. MID2 interacts with Astrin (a microtubule-organizing protein) and regulates Astrin levels to promote cell division []. MID1 and MID2 may play roles in regulating tissue remodelling in early development [].Mutations in the MID2 gene cause mental retardation, X-linked 101 (MRX101) []. |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
587
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
346
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
123
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
361
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
246
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
60
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
197
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
172
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
196
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
345
 |
| Fragment?: |
false |
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| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents B-box-type zinc finger domains, which are around 40 residues in length. B-box zinc fingers can be divided into two groups, where types 1 and 2 B-box domains differ in their consensus sequence and in the spacing of the 7-8 zinc-binding residues. Several proteins contain both types 1 and 2 B-boxes, suggesting some level of cooperativity between these two domains. B-box domains are found in over 1500 proteins from a variety of organisms. They are found in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). TRIM proteins contain a type 2 B-box domain, and may also contain a type 1 B-box. In proteins that do not contain RING or coiled-coil domains, the B-box domain is primarily type 2. Many type 2 B-box proteins are involved in ubiquitination. Proteins containing a B-box zinc finger domain include transcription factors, ribonucleoproteins and proto-oncoproteins; for example, MID1, MID2, TRIM9, TNL, TRIM36, TRIM63, TRIFIC, NCL1 and CONSTANS-like proteins [].The microtubule-associated E3 ligase MID1 () contains a type 1 B-box zinc finger domain. MID1 specifically binds Alpha-4, which in turn recruits the catalytic subunit of phosphatase 2A (PP2Ac). This complex is required for targeting of PP2Ac for proteasome-mediated degradation. The MID1 B-box coordinates two zinc ions and adopts a β/β/α cross-brace structure similar to that of ZZ, PHD, RING and FYVE zinc fingers [, ]. |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
716
 |
| Fragment?: |
false |
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•
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
199
 |
| Fragment?: |
true |
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