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Search results 601 to 645 out of 645 for Ndc80

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0.018s

Type

Details

Score

Protein

B8JK52

Organism:	Mus musculus/domesticus
Length:	177
Fragment?:	false

•

Publication

12242294 | -

First Author:	Jin QW
Year:	2002
Journal:	Mol Cell Biol
Title:	The mal2p protein is an essential component of the fission yeast centromere.
Volume:	22
Issue:	20
Pages:	7168-83

•

Publication

18045986 | -

First Author:	Cheeseman IM
Year:	2008
Journal:	Mol Biol Cell
Title:	KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates.
Volume:	19
Issue:	2
Pages:	587-94

•

Protein Domain

IPR018464 | CENP-O

Type:

Family

Description:

This entry represents centromere protein O (CENP-O) and its homologues in yeasts, Mcm21 and Mal2. In humans, centromere protein O (CENP-O) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation []. CENP-O mediates the attachment of the centromere to the mitotic spindle by forming essential interactions between the microtubule-associated outer kinetochore proteins and the centromere-associated inner kinetochore proteins. CENP-O modulates the kinetochore-bound levels of NDC80 complex []. It may be involved in incorporation of newly synthesized CENP-A into centromeres via its interaction with the CENPA-NAC complex [].In Saccharomyces cerevisiae, Mcm21 is a component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p), which links kinetochore subunits with subunits bound to microtubules during kinetochore assembly [, ]. In Schizosaccharomyces pombe, Mal2 is a component of the Sim4 complex, which is required for loading the DASH complex onto the kinetochore via interaction with Dad1 []. It plays a role in the maintenance of core chromatin structure and kinetochore function [].

•

Protein Domain

IPR035425 | CENP-T/H4_C

Type:

Domain

Description:

This domain is the C-terminal histone fold domain of CENP-T, which associates with chromatin [, ]. Proteins containing this domain also include Histone H4. CENP-T is a family of vertebral kinetochore proteins that associates directly with CENP-W. The N terminus of CENP-T proteins interacts directly with the Ndc80 complex in the outer kinetochore. Importantly, the CENP-T-W complex does not directly associate with CENP-A, but with histone H3 in the centromere region. CENP-T and -W form a hetero-tetramer with CENP-S and -X and bind to a ~100 bp region of nucleosome-free DNA forming a nucleosome-like structure. The DNA-CENP-T-W-S-X complex is likely to be associated with histone H3-containing nucleosomes rather than with CENP-nucleosomes [, , ].Histone H4 is one of the five histones, along with H1/H5, H2A, H2B and H3. Two copies of each of the H2A, H2B, H3, and H4 histones ensemble to form the core of the nucleosome []. The nucleosome forms octameric structure that wraps DNA in a left-handed manner. H3 is a highly conserved protein of 135 amino acid residues [, ]. Histones can undergo several different types of post-translational modifications that affect transcription, DNA repair, DNA replication and chromosomal stability. The sequence of histone H4 has remained almost invariant in more then 2 billion years of evolution [, , ].

•

Protein

Q3TJM4

Organism:	Mus musculus/domesticus
Length:	515
Fragment?:	false

•

Publication

22304917 | -

First Author:	Nishino T
Year:	2012
Journal:	Cell
Title:	CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold.
Volume:	148
Issue:	3
Pages:	487-501

•

Publication

18007590 | -

First Author:	McClelland SE
Year:	2007
Journal:	EMBO J
Title:	The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.
Volume:	26
Issue:	24
Pages:	5033-47

•

Publication

19289083 | -

First Author:	Welburn JP
Year:	2009
Journal:	Dev Cell
Title:	The human kinetochore Ska1 complex facilitates microtubule depolymerization-coupled motility.
Volume:	16
Issue:	3
Pages:	374-85

•

Publication

28535371 | J:241850

First Author:	Naiman N
Year:	2017
Journal:	Dev Cell
Title:	Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Volume:	41
Issue:	4
Pages:	349-365.e3

•

Publication

33798452 | J:314103

First Author:	Ulmke PA
Year:	2021
Journal:	Stem Cell Reports
Title:	Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume:	16
Issue:	4
Pages:	968-984

•

Protein

Q9CYF0

Organism:	Mus musculus/domesticus
Length:	331
Fragment?:	false

•

Publication

6808351 | -

First Author:	Doenecke D
Year:	1982
Journal:	Mol Cell Biochem
Title:	Acetylation of histones in nucleosomes.
Volume:	44
Issue:	2
Pages:	113-28

•

Publication

3340182 | -

First Author:	Ebralidse KK
Year:	1988
Journal:	Nature
Title:	A highly basic histone H4 domain bound to the sharply bent region of nucleosomal DNA.
Volume:	331
Issue:	6154
Pages:	365-7

•

Publication

14633972 | -

First Author:	De Wulf P
Year:	2003
Journal:	Genes Dev
Title:	Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes.
Volume:	17
Issue:	23
Pages:	2902-21

•

Publication

21440680 | J:171624

First Author:	Machold R
Year:	2011
Journal:	Gene Expr Patterns
Title:	Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.
Volume:	11
Issue:	5-6
Pages:	349-59

•

Protein

Q61667

Organism:	Mus musculus/domesticus
Length:	55
Fragment?:	true

•

Publication

2041803 | -

First Author:	Wells D
Year:	1991
Journal:	Nucleic Acids Res
Title:	Histone and histone gene compilation and alignment update.
Volume:	19 Suppl

Pages:	2173-88

•

Publication

19334288 | J:148410

First Author:	Combes AN
Year:	2009
Journal:	Dev Dyn
Title:	Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume:	238
Issue:	5
Pages:	1033-41

•

Protein

P62806

Organism:	Mus musculus/domesticus
Length:	103
Fragment?:	false

•

Protein

B2RTM0

Organism:	Mus musculus/domesticus
Length:	103
Fragment?:	false

•

Publication

8121801 | -

First Author:	Thatcher TH
Year:	1994
Journal:	Nucleic Acids Res
Title:	Phylogenetic analysis of the core histones H2A, H2B, H3, and H4.
Volume:	22
Issue:	2
Pages:	174-9

•

Publication

16472024 | -

First Author:	Bhasin M
Year:	2006
Journal:	J Comput Biol
Title:	Recognition and classification of histones using support vector machine.
Volume:	13
Issue:	1
Pages:	102-12

•

Publication

16622420 | -

First Author:	Okada M
Year:	2006
Journal:	Nat Cell Biol
Title:	The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
Volume:	8
Issue:	5
Pages:	446-57

•

Publication

20436479 | J:157819

First Author:	Shimogori T
Year:	2010
Journal:	Nat Neurosci
Title:	A genomic atlas of mouse hypothalamic development.
Volume:	13
Issue:	6
Pages:	767-75

•

Publication

16622419 | -

First Author:	Foltz DR
Year:	2006
Journal:	Nat Cell Biol
Title:	The human CENP-A centromeric nucleosome-associated complex.
Volume:	8
Issue:	5
Pages:	458-69

•

Publication

16079914 | -

First Author:	Liu X
Year:	2005
Journal:	EMBO J
Title:	Molecular analysis of kinetochore architecture in fission yeast.
Volume:	24
Issue:	16
Pages:	2919-30

•

Publication

16919269 | J:112701

First Author:	Bailey PJ
Year:	2006
Journal:	Exp Cell Res
Title:	A global genomic transcriptional code associated with CNS-expressed genes.
Volume:	312
Issue:	16
Pages:	3108-19

•

Publication

- | J:237616

First Author:	MGI and IMPC
Year:	2017
Journal:	MGI Direct Data Submission
Title:	MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)

•

Publication

15226823 | J:93300

First Author:	Blackshaw S
Year:	2004
Journal:	PLoS Biol
Title:	Genomic analysis of mouse retinal development.
Volume:	2
Issue:	9
Pages:	E247

•

Publication

- | J:136110

First Author:	Velocigene
Year:	2008
Journal:	MGI Direct Data Submission
Title:	Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)

•

Publication

- | J:155845

First Author:	Wellcome Trust Sanger Institute
Year:	2010
Journal:	MGI Direct Data Submission
Title:	Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute

•

Publication

10725249 | J:60984

First Author:	Ko MS
Year:	2000
Journal:	Development
Title:	Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume:	127
Issue:	8
Pages:	1737-49

•

Publication

- | J:80155

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data

•

Publication

34321999 | J:313619

First Author:	Bedogni F
Year:	2021
Journal:	Front Mol Neurosci
Title:	Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume:	14

Pages:	686034

•

Publication

- | J:157065

First Author:	Helmholtz Zentrum Muenchen GmbH
Year:	2010
Journal:	MGI Direct Data Submission
Title:	Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)

•

Publication

14681479 | J:122989

First Author:	Visel A
Year:	2004
Journal:	Nucleic Acids Res
Title:	GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume:	32
Issue:	Database issue
Pages:	D552-6

•

Publication

- | J:73796

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Function or Process or Component Unknown following Literature Review

•

Publication

- | J:171409

First Author:	GUDMAP Consortium
Year:	2004
Journal:	www.gudmap.org
Title:	GUDMAP: the GenitoUrinary Development Molecular Anatomy Project

•

Publication

14610273 | J:86696

First Author:	Zambrowicz BP
Year:	2003
Journal:	Proc Natl Acad Sci U S A
Title:	Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume:	100
Issue:	24
Pages:	14109-14

•

Publication

- | J:342604

First Author:	UniProt-GOA
Year:	2012

Title:	Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

•

Publication

21267068 | J:153498

First Author:	Diez-Roux G
Year:	2011
Journal:	PLoS Biol
Title:	A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume:	9
Issue:	1
Pages:	e1000582

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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