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Search results 601 to 677 out of 677 for Nhlh1

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Type Details Score
Publication
8543157 | J:30431
First Author: Ishibashi M
Year: 1995
Journal: Genes Dev
Title: Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.
Volume: 9
Issue: 24
Pages: 3136-48
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Publication
18160702 | J:132652
First Author: Mattar P
Year: 2008
Journal: Mol Cell Biol
Title: Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.
Volume: 28
Issue: 5
Pages: 1456-69
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Publication
27559308 | J:273440
 
First Author: Żak M
Year: 2016
Journal: Front Cell Neurosci
Title: LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.
Volume: 10
Pages: 186
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Publication
32880858 | J:311887
First Author: Filova I
Year: 2020
Journal: Mol Neurobiol
Title: Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers.
Volume: 57
Issue: 12
Pages: 5307-5323
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Publication
22292060 | J:242970
First Author: Jahan I
Year: 2012
Journal: PLoS One
Title: Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.
Volume: 7
Issue: 1
Pages: e30853
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Publication
23614009 | J:200106
First Author: Duncan JS
Year: 2013
Journal: PLoS One
Title: Continued expression of GATA3 is necessary for cochlear neurosensory development.
Volume: 8
Issue: 4
Pages: e62046
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Publication
20615956 | J:162313
First Author: Bedogni F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.
Volume: 107
Issue: 29
Pages: 13129-34
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Publication
29867344 | J:310819
 
First Author: Makrides N
Year: 2018
Journal: Front Mol Neurosci
Title: Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain.
Volume: 11
Pages: 152
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Publication
24148613 | J:206224
First Author: Dixit R
Year: 2014
Journal: Gene Expr Patterns
Title: Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.
Volume: 14
Issue: 1
Pages: 42-54
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Publication
10051400 | J:52606
First Author: Eddleston J
Year: 1999
Journal: Genomics
Title: Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp).
Volume: 56
Issue: 2
Pages: 149-59
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Publication
39106860 | J:353339
First Author: Butts JC
Year: 2024
Journal: Dev Cell
Title: A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain.
Volume: 59
Issue: 16
Pages: 2171-2188.e7
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Publication
35361962 | J:337771
First Author: El-Saafin F
Year: 2022
Journal: Cell Death Differ
Title: Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
Volume: 29
Issue: 5
Pages: 1013-1027
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Publication
21150899 | J:167212
First Author: Gibson P
Year: 2010
Journal: Nature
Title: Subtypes of medulloblastoma have distinct developmental origins.
Volume: 468
Issue: 7327
Pages: 1095-9
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Publication
33798452 | J:314103
First Author: Ulmke PA
Year: 2021
Journal: Stem Cell Reports
Title: Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Volume: 16
Issue: 4
Pages: 968-984
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Publication
25053427 | J:214095
First Author: Osipovich AB
Year: 2014
Journal: Development
Title: Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Volume: 141
Issue: 15
Pages: 2939-49
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Publication
21440680 | J:171624
First Author: Machold R
Year: 2011
Journal: Gene Expr Patterns
Title: Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip.
Volume: 11
Issue: 5-6
Pages: 349-59
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Publication
18557763 | J:140152
First Author: Stevens JD
Year: 2008
Journal: Differentiation
Title: Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.
Volume: 76
Issue: 9
Pages: 1006-22
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Publication
30635555 | J:270210
First Author: Loo L
Year: 2019
Journal: Nat Commun
Title: Single-cell transcriptomic analysis of mouse neocortical development.
Volume: 10
Issue: 1
Pages: 134
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Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Nhlh1<em1Smoc> | MGI:7291309
Name: nescient helix loop helix 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475880 | C57BL/6JSmoc-Nhlh1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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GXD Expression
GXD Expression
 
Probe: MGI:2148090
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6452589
Age: embryonic day 10.5
Note: Strong expression in ventrolateral region of neural tube. Expression also in region of dorsal neural tube, marking subpopularion of dorsal sensory interneurons. Expression in a few cells more medially, within Nhlh1 expression domain, likely to represent motor neurons.
Specimen Label: 4F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:2148090
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6452589
Age: embryonic day 10.5
Note: Strong expression in ventrolateral region of neural tube. Expression also in region of dorsal neural tube, marking subpopularion of dorsal sensory interneurons. Expression in a few cells more medially, within Nhlh1 expression domain, likely to represent motor neurons.
Specimen Label: 4G
Detected: true
Specimen Num: 2
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Publication
1763056 | J:19155
First Author: Xia Y
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia.
Volume: 88
Issue: 24
Pages: 11416-20
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Protein
A2AD40
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Publication
1396592 | -
First Author: Aplan PD
Year: 1992
Journal: EMBO J
Title: The SCL gene product: a positive regulator of erythroid differentiation.
Volume: 11
Issue: 11
Pages: 4073-81
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Publication
2752424 | -
First Author: Mellentin JD
Year: 1989
Journal: Cell
Title: lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif.
Volume: 58
Issue: 1
Pages: 77-83
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Publication
30185409 | J:266594
 
First Author: Chiu SK
Year: 2018
Journal: Development
Title: A novel role for Lyl1 in primitive erythropoiesis.
Volume: 145
Issue: 19
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Protein Domain
IPR040238 | TAL-like
Type: Family
Description: This entry includes highly related proteins with a Myc-type, basic helix-loop-helix (bHLH) domain, including T-cell acute lymphocytic leukemia proteins 1 and 2 (TAL1 and TAL2), helix-loop-helix proteins 1 and 2 (NHLH1/HEN1 and NHLH2/HEN2), and protein lyl-1 (LYL1). The bHLH domain is required for protein dimerization and DNA binding []. TAL1 may be a positive regulator of erythroid differentiation []. The TAL1 and TAL2 genes are altered in T-cell acute lymphoblastic leukemia []. The NHLH1 and NHLH2 genes are expressed in the developing nervous system, especially cell lines derived from neuroblastoma, PNET, and small cell lung cancer [], and the proteins may have regulatory functions in the developing nervous system []. LYL1 has a role in primitive erythropoiesis []. A chromosomal aberration involving the LYL1 gene may be a cause of a form of T-cell acute lymphoblastic leukemia [].
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Publication
9090387 | J:39356
First Author: Good DJ
Year: 1997
Journal: Nat Genet
Title: Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene.
Volume: 15
Issue: 4
Pages: 397-401
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Protein
Q64221
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: false
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Protein
Q02576
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein
P27792
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: false
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Protein
P22091
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q62282
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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Protein
A0A571BE88
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
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Protein
Q3TZH7
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q9JK33
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q2TB09
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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