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Search results 601 to 700 out of 1772 for Parkinson

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Type Details Score
Publication
34127548 | J:335457
 
First Author: Chenery AL
Year: 2021
Journal: Life Sci Alliance
Title: IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection.
Volume: 4
Issue: 8
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Publication
23434585 | J:245300
First Author: Nkansah E
Year: 2013
Journal: FEBS Lett
Title: Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography.
Volume: 587
Issue: 7
Pages: 833-9
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Publication
25348409 | J:235125
First Author: Kibbe WA
Year: 2015
Journal: Nucleic Acids Res
Title: Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data.
Volume: 43
Issue: Database issue
Pages: D1071-8
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Publication
30535239 | J:269419
First Author: Conte N
Year: 2019
Journal: Nucleic Acids Res
Title: PDX Finder: A portal for patient-derived tumor xenograft model discovery.
Volume: 47
Issue: D1
Pages: D1073-D1079
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Publication
34292621 | J:360193
First Author: Behere A
Year: 2021
Journal: J Neurosci Res
Title: Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model.
Volume: 99
Issue: 10
Pages: 2525-2539
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Publication
15755545 | J:131691
First Author: Frasier M
Year: 2005
Journal: Exp Neurol
Title: Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein.
Volume: 192
Issue: 2
Pages: 274-87
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HT Experiment
E-GEOD-74517 | Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin; germline Parkin knockout mouse hearts
Series Id: GSE74517
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:5527354 | B6.Cg-Park7<tm1Shn> Prkn<tm1Shn>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Prkn/Prkn Park7/Park7
Background: B6.Cg-Park7 Prkn
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Park7/Park7 Pink1/Pink1
Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
14752510 | J:233583
First Author: Gotoh T
Year: 2004
Journal: Cell Death Differ
Title: hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.
Volume: 11
Issue: 4
Pages: 390-402
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Publication
23447676 | J:200657
First Author: Duplan E
Year: 2013
Journal: J Cell Sci
Title: ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.
Volume: 126
Issue: Pt 9
Pages: 2124-33
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MP Term
MP:0014065 | Lewy bodies
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Gene
8398 | PLA2G6
Type: gene
Organism: human
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Publication
16041373 | -
First Author: Skibinski G
Year: 2005
Journal: Nat Genet
Title: Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia.
Volume: 37
Issue: 8
Pages: 806-8
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Publication
9891081 | -
First Author: Bertram MJ
Year: 1999
Journal: Mol Cell Biol
Title: Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.
Volume: 19
Issue: 2
Pages: 1479-85
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Publication
30415890 | J:278783
 
First Author: Chen X
Year: 2018
Journal: EBioMedicine
Title: Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease.
Volume: 37
Pages: 259-268
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Publication
26610869 | J:228204
First Author: Shen Y
Year: 2016
Journal: Am J Pathol
Title: Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.
Volume: 186
Issue: 1
Pages: 87-100
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Publication
31582719 | J:293324
First Author: Rehman A
Year: 2019
Journal: Cell Death Dis
Title: The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53.
Volume: 10
Issue: 10
Pages: 750
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Publication
19525946 | J:152569
First Author: Woodhoo A
Year: 2009
Journal: Nat Neurosci
Title: Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity.
Volume: 12
Issue: 7
Pages: 839-47
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Publication
23455610 | J:197562
First Author: Schulz A
Year: 2013
Journal: Nat Neurosci
Title: Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy.
Volume: 16
Issue: 4
Pages: 426-33
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Publication
28137778 | J:246506
First Author: Mindos T
Year: 2017
Journal: J Cell Biol
Title: Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.
Volume: 216
Issue: 2
Pages: 495-510
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Publication
18314463 | J:137558
First Author: Burgess BL
Year: 2008
Journal: J Lipid Res
Title: ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
Volume: 49
Issue: 6
Pages: 1254-67
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Publication
31586037 | J:282044
First Author: Chenery AL
Year: 2019
Journal: J Immunol
Title: Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.
Volume: 203
Issue: 10
Pages: 2724-2734
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Publication
36948193 | J:335619
First Author: Finlay CM
Year: 2023
Journal: Immunity
Title: T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity.
Volume: 56
Issue: 5
Pages: 1064-1081.e10
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Publication
22366797 | J:221848
First Author: Ghazi-Noori S
Year: 2012
Journal: Brain
Title: Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice.
Volume: 135
Issue: Pt 3
Pages: 819-32
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Gene
6622 | SNCA
Type: gene
Organism: human
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Strain
MGI:5527340 | B6.Cg-Park7<tm1Shn> Gpx1<tm1Ysh> Prkn<tm1Shn>
Attribute String: mutant strain, congenic, targeted mutation
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Strain
MGI:5517691 | B6.Cg-Park7<tm1Shn> Gpx1<tm1Ysh> Prkn<tm1Shn>/MgoldJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5494997 | STOCK Grm7<Tg(SMN2)89Ahmb> Smg6<Tg(SMN1*delta5)1Pks> Smn1<tm1Msd>/H
Attribute String: targeted mutation, transgenic, mutant stock
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Genotype
Genotype
Symbol: Gpx1/Gpx1 Prkn/Prkn Park7/Park7
Background: B6.Cg-Park7 Gpx1 Prkn
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Park7/Park7 Pink1/Pink1 Rrn3/Rrn3 Tg(Slc6a3-cre/ERT2)1Span/?
Background: involves: 129 * 129P2/OlaHsd * 129S2/SvPas * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
29718367 | J:321148
First Author: Scudamore O
Year: 2018
Journal: J Neuropathol Exp Neurol
Title: Increased Oxidative Stress Exacerbates α-Synuclein Aggregation In Vivo.
Volume: 77
Issue: 6
Pages: 443-453
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Publication
31875550 | J:282288
First Author: Wu H
Year: 2019
Journal: Cell Rep
Title: Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Volume: 29
Issue: 13
Pages: 4422-4434.e13
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Allele
Tg(Thy1-SNCA*A30P)18Pjk | MGI:2445720
Name: transgene insertion 18, Philipp J Kahle
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(SNCA*A30P)192Rwm | MGI:5543905
Name: transgene insertion 192, Richard Wade-Martins
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Synj1<tm2.1Pdc> | MGI:6120537
 
Name: synaptojanin 1; targeted mutation 2.1, Pietro De Camilli
Allele Type: Targeted
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Publication
39167658 | J:353846
First Author: Kokotos AC
Year: 2024
Journal: Sci Adv
Title: Phosphoglycerate kinase is a central leverage point in Parkinson's disease-driven neuronal metabolic deficits.
Volume: 10
Issue: 34
Pages: eadn6016
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Publication
33299968 | J:321323
First Author: Bus C
Year: 2020
Journal: iScience
Title: Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors.
Volume: 23
Issue: 12
Pages: 101797
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Publication
33895869 | J:355627
First Author: Kang SS
Year: 2021
Journal: Acta Neuropathol
Title: ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease.
Volume: 142
Issue: 1
Pages: 139-158
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Publication
12833159 | J:86904
First Author: Mburu P
Year: 2003
Journal: Nat Genet
Title: Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.
Volume: 34
Issue: 4
Pages: 421-8
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Publication
15457338 | J:93069
First Author: Quwailid MM
Year: 2004
Journal: Mamm Genome
Title: A gene-driven ENU-based approach to generating an allelic series in any gene.
Volume: 15
Issue: 8
Pages: 585-91
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Publication
21471385 | J:171267
First Author: Banks GT
Year: 2011
Journal: J Neurosci
Title: Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.
Volume: 31
Issue: 14
Pages: 5483-94
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Publication
29128334 | J:263469
First Author: Malty RH
Year: 2017
Journal: Cell Syst
Title: A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Volume: 5
Issue: 6
Pages: 564-577.e12
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Publication
24488133 | J:210181
 
First Author: Neuner J
Year: 2014
Journal: Sci Rep
Title: A30P α-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network.
Volume: 4
Pages: 3931
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Publication
16732273 | J:110266
First Author: Cardona AE
Year: 2006
Journal: Nat Neurosci
Title: Control of microglial neurotoxicity by the fractalkine receptor.
Volume: 9
Issue: 7
Pages: 917-24
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Protein
A0A1W2P6H5
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
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Protein
Q8C910
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
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Protein Domain
IPR039701 | HS1BP3
Type: Family
Description: Hematopoietic lineage cell-specific protein-1 (HS1) binding protein 3 (HS1BP3) associates with HS1 proteins through their SH3 domains, suggesting a role in mediating signaling. It has been reported that HS1BP3 might affect the IL-2 signaling pathway in hematopoietic lineage cells []. Mutations in HS1BP3 may also be associated with familial Parkinson disease and essential tremor [, ]. HS1BP3 contains a PX domain, a leucine zipper, motifs similar to immunoreceptor tyrosine-based inhibitory motif and proline-rich regions [].
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HT Experiment
E-GEOD-72321 | Engrailed homeoprotein protects mesencephalic dopaminergic neurons from oxidative stress
Series Id: GSE72321
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
24064336 | J:205004
First Author: Casadei N
Year: 2014
Journal: Hum Mol Genet
Title: Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Volume: 23
Issue: 3
Pages: 767-81
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Publication
10964942 | J:64205
First Author: Kahle PJ
Year: 2000
Journal: J Neurosci
Title: Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
Volume: 20
Issue: 17
Pages: 6365-73
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Publication
23363402 | J:199504
First Author: Fagerqvist T
Year: 2013
Journal: J Neurochem
Title: Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.
Volume: 126
Issue: 1
Pages: 131-44
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Publication
33041770 | J:308537
 
First Author: Stylianou M
Year: 2020
Journal: Front Neurosci
Title: Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein.
Volume: 14
Pages: 579867
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Publication
29524634 | J:262431
 
First Author: Robson E
Year: 2018
Journal: Neuroscience
Title: Impaired Fast Network Oscillations and Mitochondrial Dysfunction in a Mouse Model of Alpha-synucleinopathy (A30P).
Volume: 377
Pages: 161-173
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Publication
29623065 | J:337639
 
First Author: Almandoz-Gil L
Year: 2018
Journal: Front Neurol
Title: In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons.
Volume: 9
Pages: 180
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Publication
24851801 | J:214308
 
First Author: Lindström V
Year: 2014
Journal: Neurobiol Dis
Title: Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice.
Volume: 69
Pages: 134-43
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Publication
31422098 | J:282744
 
First Author: Keane PC
Year: 2019
Journal: Neurosci Lett
Title: Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice.
Volume: 711
Pages: 134437
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Publication
23209687 | J:195450
First Author: Schell H
Year: 2012
Journal: PLoS One
Title: Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned α-synuclein transgenic mice.
Volume: 7
Issue: 11
Pages: e50245
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Publication
22579457 | J:194440
First Author: Szegő ÉM
Year: 2013
Journal: Neurobiol Aging
Title: Impairment of the septal cholinergic neurons in MPTP-treated A30P α-synuclein mice.
Volume: 34
Issue: 2
Pages: 589-601
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Publication
28450268 | J:260980
 
First Author: Lindström V
Year: 2017
Journal: Mol Cell Neurosci
Title: Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage.
Volume: 82
Pages: 143-156
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Publication
16872721 | J:128051
First Author: Freichel C
Year: 2007
Journal: Neurobiol Aging
Title: Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice.
Volume: 28
Issue: 9
Pages: 1421-35
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Publication
19272424 | J:149844
First Author: Schell H
Year: 2009
Journal: Neuroscience
Title: Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice.
Volume: 160
Issue: 4
Pages: 796-804
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Publication
29541535 | J:340132
First Author: Ekmark-Lewén S
Year: 2018
Journal: Brain Behav
Title: Early fine motor impairment and behavioral dysfunction in (Thy-1)-h[A30P] alpha-synuclein mice.
Volume: 8
Issue: 3
Pages: e00915
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Publication
18541383 | J:140784
First Author: Schnack C
Year: 2008
Journal: Neuroscience
Title: Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins.
Volume: 154
Issue: 4
Pages: 1450-7
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Publication
11733371 | J:100981
First Author: Kahle PJ
Year: 2001
Journal: Am J Pathol
Title: Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model.
Volume: 159
Issue: 6
Pages: 2215-25
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Publication
34326719 | J:343002
 
First Author: Szegő ÉM
Year: 2021
Journal: Front Neurosci
Title: A β-Wrapin Targeting the N-Terminus of α-Synuclein Monomers Reduces Fibril-Induced Aggregation in Neurons.
Volume: 15
Pages: 696440
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Publication
28833174 | J:247316
First Author: Rotermund C
Year: 2017
Journal: J Neurochem
Title: Enhanced motivation to alcohol in transgenic mice expressing human α-synuclein.
Volume: 143
Issue: 3
Pages: 294-305
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Publication
34557068 | J:311193
 
First Author: Veys L
Year: 2021
Journal: Front Neurosci
Title: Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson's Disease.
Volume: 15
Pages: 726476
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Allele
Tg(Slc6a3-PARK2*Q311X)AXwy | MGI:3845880
Name: transgene insertion A, X William Yang
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Thy1-SNCA*A30P)18Pjk/Tg(Thy1-SNCA*A30P)18Pjk
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
20049710 | J:225033
First Author: Morais VA
Year: 2009
Journal: EMBO Mol Med
Title: Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.
Volume: 1
Issue: 2
Pages: 99-111
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Publication
33685343 | J:351586
First Author: Liu YT
Year: 2021
Journal: Autophagy
Title: Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC.
Volume: 17
Issue: 11
Pages: 3753-3762
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
32325033 | J:298772
First Author: Pourhaghighi R
Year: 2020
Journal: Cell Syst
Title: BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Volume: 10
Issue: 4
Pages: 333-350.e14
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Publication
31929527 | J:284068
First Author: Zhang T
Year: 2020
Journal: PLoS Genet
Title: High-throughput discovery of genetic determinants of circadian misalignment.
Volume: 16
Issue: 1
Pages: e1008577
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Publication
36737727 | J:333098
First Author: Chee JM
Year: 2023
Journal: BMC Biol
Title: Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Volume: 21
Issue: 1
Pages: 22
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Publication
38802071 | J:353867
First Author: Watzlawik JO
Year: 2024
Journal: Autophagy
Title: Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.
Volume: 20
Issue: 9
Pages: 2076-2091
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Protein Domain
IPR037901 | HS1BP3_PX
Type: Domain
Description: Hematopoietic lineage cell-specific protein-1 (HS1) binding protein 3 (HS1BP3) associates with HS1 proteins through their SH3 domains, suggesting a role in mediating signaling. It has been reported that HS1BP3 might affect the IL-2 signaling pathway in hematopoietic lineage cells []. Mutations in HS1BP3 may also be associated with familial Parkinson disease and essential tremor [, ]. HS1BP3 contains a PX domain, a leucine zipper, motifs similar to immunoreceptor tyrosine-based inhibitory motif and proline-rich regions [].This entry represents the PX domain of HS1BP3. In general, the PX domain interacts with PIs and plays a role in targeting proteins to PI-enriched membranes [].
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Publication
11359883 | J:69529
First Author: Rathke-Hartlieb S
Year: 2001
Journal: J Neurochem
Title: Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
Volume: 77
Issue: 4
Pages: 1181-4
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Publication
24619358 | J:210987
First Author: Diepenbroek M
Year: 2014
Journal: Hum Mol Genet
Title: Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Volume: 23
Issue: 15
Pages: 3975-89
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Publication
31269451 | J:290865
First Author: Szegő ÉM
Year: 2019
Journal: Cell Rep
Title: Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies.
Volume: 28
Issue: 1
Pages: 65-77.e6
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Publication
33347975 | J:301267
 
First Author: Tweedy C
Year: 2021
Journal: Neurobiol Dis
Title: Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein.
Volume: 149
Pages: 105226
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Publication
30092270 | J:268718
 
First Author: Paiva I
Year: 2018
Journal: Neurobiol Dis
Title: Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Volume: 119
Pages: 121-135
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Allele
Tg(Th-SNCA*A30P*A53T)39Eric | MGI:3530031
Name: transgene insertion 39, Eric K Richfield
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Slc6a3-PARK2*Q311X)DXwy | MGI:3845881
Name: transgene insertion D, X William Yang
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
32424101 | J:290165
First Author: Cao M
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1.
Volume: 117
Issue: 22
Pages: 12428-12434
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Publication
36792618 | J:349096
First Author: Ng XY
Year: 2023
Journal: NPJ Parkinsons Dis
Title: Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology.
Volume: 9
Issue: 1
Pages: 26
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Publication
10590261 | J:64960
First Author: Takemoto Y
Year: 1999
Journal: Int Immunol
Title: Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3.
Volume: 11
Issue: 12
Pages: 1957-64
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Publication
16211613 | -
First Author: Higgins JJ
Year: 2006
Journal: Mov Disord
Title: HS1-BP3 gene variant is common in familial essential tremor.
Volume: 21
Issue: 3
Pages: 306-9
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Publication
16980962 | J:113152
First Author: Smith WW
Year: 2006
Journal: Nat Neurosci
Title: Kinase activity of mutant LRRK2 mediates neuronal toxicity.
Volume: 9
Issue: 10
Pages: 1231-3
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HT Experiment
E-GEOD-43670 | The 3'UTR of FMR1 mRNA is a target of miR101, miR129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse
Series Id: GSE43670
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE241218 | Transcriptomic analysis of cortex tissue from neuron-specific Bmal1 KO mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Chchd2<tm1Noha> | MGI:6342881
Name: coiled-coil-helix-coiled-coil-helix domain containing 2; targeted mutation 1, Nobutaka Hattori
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
28650954 | J:246057
 
First Author: Karp NA
Year: 2017
Journal: Nat Commun
Title: Prevalence of sexual dimorphism in mammalian phenotypic traits.
Volume: 8
Pages: 15475
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Publication
29092942 | J:249366
First Author: Meehan TF
Year: 2017
Journal: Cancer Res
Title: PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models.
Volume: 77
Issue: 21
Pages: e62-e66
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Publication
29026089 | J:253587
First Author: Bowl MR
Year: 2017
Journal: Nat Commun
Title: A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.
Volume: 8
Issue: 1
Pages: 886
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Publication
32005800 | J:286457
First Author: Cacheiro P
Year: 2020
Journal: Nat Commun
Title: Human and mouse essentiality screens as a resource for disease gene discovery.
Volume: 11
Issue: 1
Pages: 655
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Publication
27597528 | J:260529
 
First Author: Sen NE
Year: 2016
Journal: Neurobiol Dis
Title: Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.
Volume: 96
Pages: 115-126
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Protein
A0A1L1STR9
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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