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Search results 601 to 700 out of 1044 for Rel

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0.031s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
O88942
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
P97305
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
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Protein
Q60591
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
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Protein
Q9JHD3
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
B5B2N4
Organism: Mus musculus/domesticus
Length: 813  
Fragment?: false
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Protein
Q3UZ64
Organism: Mus musculus/domesticus
Length: 1076  
Fragment?: false
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Protein
Q3TTU8
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
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Protein
B5B2Q6
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
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Protein
B5B2U4
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein
A0A1U6URG8
Organism: Mus musculus/domesticus
Length: 1458  
Fragment?: false
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Protein
B5B2P6
Organism: Mus musculus/domesticus
Length: 903  
Fragment?: false
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Protein
B5B2Q2
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
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Protein
Q571K2
Organism: Mus musculus/domesticus
Length: 748  
Fragment?: true
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Protein
B5B2P7
Organism: Mus musculus/domesticus
Length: 923  
Fragment?: false
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Protein
Q9JIH4
Organism: Mus musculus/domesticus
Length: 669  
Fragment?: false
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Protein
A0A2I3BRR0
Organism: Mus musculus/domesticus
Length: 831  
Fragment?: false
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Protein
Q9JIH5
Organism: Mus musculus/domesticus
Length: 409  
Fragment?: false
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Protein
Q3UME0
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
Q3UZ77
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
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Protein
B5B2N5
Organism: Mus musculus/domesticus
Length: 717  
Fragment?: false
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Protein
B5B2U1
Organism: Mus musculus/domesticus
Length: 1060  
Fragment?: false
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Protein
B5B2N2
Organism: Mus musculus/domesticus
Length: 939  
Fragment?: false
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Protein
Q6P7T9
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
B5B2P8
Organism: Mus musculus/domesticus
Length: 702  
Fragment?: false
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Protein
B5B2N7
Organism: Mus musculus/domesticus
Length: 925  
Fragment?: false
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Protein
B5B2U2
Organism: Mus musculus/domesticus
Length: 1068  
Fragment?: false
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Protein
B5B2Q4
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
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Protein
Q8VHJ6
Organism: Mus musculus/domesticus
Length: 1458  
Fragment?: false
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Protein
Q9DBQ6
Organism: Mus musculus/domesticus
Length: 703  
Fragment?: false
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Protein
P15307
Organism: Mus musculus/domesticus
Length: 587  
Fragment?: false
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Protein
A4QPD3
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
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Protein
Q04863
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
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Protein
Q4U108
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
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Protein
A0A494BAQ2
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
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Protein
Q3U0K7
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
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Protein
Q8K220
Organism: Mus musculus/domesticus
Length: 555  
Fragment?: false
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Allele
Relb<tm1Brv> | MGI:2179545
Name: avian reticuloendotheliosis viral (v-rel) oncogene related B; targeted mutation 1, Rodrigo Bravo
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nfatc4<tm1Jmk> | MGI:2388915
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4; targeted mutation 1, Jeffery D Molkentin
Allele Type: Targeted
Attribute String: Null/knockout
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GO Term
GO:0071159 | NF-kappaB complex
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Protein
P25799
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein
Q9WTK5
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
Q3UG25
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
Q4U105
Organism: Mus musculus/domesticus
Length: 900  
Fragment?: false
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Protein
Q3UV15
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
Q3ULT8
Organism: Mus musculus/domesticus
Length: 899  
Fragment?: false
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Protein
A0A494B9Y5
Organism: Mus musculus/domesticus
Length: 878  
Fragment?: false
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Protein
Q3U5V4
Organism: Mus musculus/domesticus
Length: 806  
Fragment?: true
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Strain
MGI:7580411 | B6.129S2-Relb<tm1Brv>/AlexJ
Attribute String: congenic, mutant strain, targeted mutation
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Publication
7834753 | J:22675
First Author: Weih F
Year: 1995
Journal: Cell
Title: Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family.
Volume: 80
Issue: 2
Pages: 331-40
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Publication
8879226 | J:110747
First Author: Snapper CM
Year: 1996
Journal: J Exp Med
Title: B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching.
Volume: 184
Issue: 4
Pages: 1537-41
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Publication
11489970 | J:70818
First Author: Weih DS
Year: 2001
Journal: J Immunol
Title: Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines.
Volume: 167
Issue: 4
Pages: 1909-19
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Publication
9164938 | J:40630
First Author: Weih F
Year: 1997
Journal: J Immunol
Title: Multifocal defects in immune responses in RelB-deficient mice.
Volume: 158
Issue: 11
Pages: 5211-8
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Publication
23530124 | J:198218
First Author: Cowan JE
Year: 2013
Journal: J Exp Med
Title: The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
Volume: 210
Issue: 4
Pages: 675-81
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Publication
21896778 | J:178327
First Author: Ganeff C
Year: 2011
Journal: Mol Cell Biol
Title: Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.
Volume: 31
Issue: 21
Pages: 4319-34
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Publication
28960101 | J:271488
First Author: Nair PM
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation.
Volume: 58
Issue: 3
Pages: 352-365
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Publication
10510387 | J:118966
First Author: Caamaño J
Year: 1999
Journal: J Immunol
Title: The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii.
Volume: 163
Issue: 8
Pages: 4453-61
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Publication
26806881 | J:246876
First Author: Baik S
Year: 2016
Journal: Eur J Immunol
Title: Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK(+) medullary epithelial progenitors.
Volume: 46
Issue: 4
Pages: 857-62
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Strain
MGI:3844539 | B6;129S7-Nfatc4<tm1Jmk>/J
Attribute String: mutant stock, targeted mutation
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Allele
Tg(Myh6-NFATC4)#Eno | MGI:3056187
Name: transgene insertion, Eric N Olson
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Allele
Tg(Rell1-EGFP)KH57Gsat | MGI:4847371
Name: transgene insertion KH57, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Genotype
Genotype
Symbol: Relb/Relb
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Relb/Relb
Background: either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfatc4/Nfatc4
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Relb/Relb
Background: involves: 129S2/SvPas
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9CS00
Organism: Mus musculus/domesticus
Length: 772  
Fragment?: false
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Protein
A1L013
Organism: Mus musculus/domesticus
Length: 772  
Fragment?: false
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Publication
10842059 | -
First Author: Lin P
Year: 2000
Journal: Mech Dev
Title: Cactin, a conserved protein that interacts with the Drosophila IkappaB protein cactus and modulates its function.
Volume: 94
Issue: 1-2
Pages: 57-65
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Publication
9416840 | J:44931
First Author: Huguet C
Year: 1997
Journal: Oncogene
Title: Rel/NF-kappa B transcription factors and I kappa B inhibitors: evolution from a unique common ancestor.
Volume: 15
Issue: 24
Pages: 2965-74
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Protein Domain
IPR019134 | Cactin_C
Type: Domain
Description: This entry represents the C-terminal 200 residues of the cactin protein, which is necessary for the association of cactin with the IkappaB protein cactus, as one of the intracellular members of the Rel complex. The Rel (NF-kappaB) pathway is conserved in invertebrates and vertebrates. In mammals, it controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development and in the establishment of dorsal-ventral polarity in the early embryo []. Most members of the family also have the conserved mid region of cactin () further upstream.
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Publication
32044112 | J:294539
 
First Author: Saha I
Year: 2020
Journal: Cell Immunol
Title: RelB suppresses type I Interferon signaling in dendritic cells.
Volume: 349
Pages: 104043
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Publication
18413714 | J:133763
First Author: Puto LA
Year: 2008
Journal: Genes Dev
Title: Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation.
Volume: 22
Issue: 8
Pages: 998-1010
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Publication
16982744 | J:112934
First Author: Croxton R
Year: 2006
Journal: Cancer Res
Title: Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.
Volume: 66
Issue: 18
Pages: 9026-35
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Allele
Nfatc2<tm1Glm> | MGI:2182740
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2; targeted mutation 1, Laurie H Glimcher
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nfkb2<tm1Rsch> | MGI:2675476
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; targeted mutation 1, Roland Schmid
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nfat5<tm1Snh> | MGI:3050805
Name: nuclear factor of activated T cells 5; targeted mutation 1, Steffan N Ho
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
10811847 | J:135883
First Author: Passier R
Year: 2000
Journal: J Clin Invest
Title: CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo.
Volume: 105
Issue: 10
Pages: 1395-406
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Strain
MGI:5004010 | STOCK Tg(Rell1-EGFP)KH57Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Nfkb2/Nfkb2
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-NFATC4)#Eno/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Allele
Relb<Tg(H2-K1/GH1)106Bri> | MGI:2179544
Name: avian reticuloendotheliosis viral (v-rel) oncogene related B; transgene insertion 106, Ralph L Brinster
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Null/knockout
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Publication
20530871 | J:163720
First Author: Gómez-Sintes R
Year: 2010
Journal: J Clin Invest
Title: NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy.
Volume: 120
Issue: 7
Pages: 2432-45
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Publication
17229811 | J:121907
First Author: Alfieri CM
Year: 2007
Journal: Am J Physiol Cell Physiol
Title: Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle.
Volume: 292
Issue: 5
Pages: C1887-94
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Publication
8612134 | J:32728
First Author: Hodge MR
Year: 1996
Journal: Immunity
Title: Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice.
Volume: 4
Issue: 4
Pages: 397-405
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Publication
22738913 | J:191029
First Author: Gerlach K
Year: 2012
Journal: Cancer Res
Title: Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.
Volume: 72
Issue: 17
Pages: 4340-50
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Publication
11309414 | J:68943
First Author: Horsley V
Year: 2001
Journal: J Cell Biol
Title: Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway.
Volume: 153
Issue: 2
Pages: 329-38
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Publication
10620601 | J:59243
First Author: Ranger AM
Year: 2000
Journal: J Exp Med
Title: The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis.
Volume: 191
Issue: 1
Pages: 9-22
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Publication
18566603 | J:154264
First Author: Jansen KM
Year: 2008
Journal: Cell Death Differ
Title: Prostaglandin F2alpha promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE.
Volume: 15
Issue: 10
Pages: 1619-28
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Publication
19318584 | J:147351
First Author: Maxeiner JH
Year: 2009
Journal: Cancer Res
Title: A key regulatory role of the transcription factor NFATc2 in bronchial adenocarcinoma via CD8+ T lymphocytes.
Volume: 69
Issue: 7
Pages: 3069-76
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Publication
10952728 | J:64133
First Author: Tsytsykova AV
Year: 2000
Journal: J Exp Med
Title: Nuclear factor of activated T cells transcription factor NFATp controls superantigen-induced lethal shock.
Volume: 192
Issue: 4
Pages: 581-6
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Publication
19526482 | J:152860
First Author: Wang J
Year: 2009
Journal: J Pathol
Title: Transcription factor Nfat1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes.
Volume: 219
Issue: 2
Pages: 163-72
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Publication
22844476 | J:189722
First Author: Via LE
Year: 2012
Journal: PLoS One
Title: The transcription factor NFATp plays a key role in susceptibility to TB in mice.
Volume: 7
Issue: 7
Pages: e41427
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Genotype
Genotype
Symbol: Nfatc2/Nfatc2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfatc4/Nfatc4 Tg(Myh6-Ppp3ca)37Eno/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfatc3/Nfatc3 Nfatc4/Nfatc4
Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nfatc3/Nfatc3<+> Nfatc4/Nfatc4
Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
9837938 | J:64812
First Author: Hu MC
Year: 1998
Journal: J Biol Chem
Title: Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity.
Volume: 273
Issue: 50
Pages: 33561-5
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Publication
17991436 | J:127749
First Author: Hochrainer K
Year: 2007
Journal: FEBS Lett
Title: Hypo-phosphorylation leads to nuclear retention of NF-kappaB p65 due to impaired IkappaBalpha gene synthesis.
Volume: 581
Issue: 28
Pages: 5493-9
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Protein
A0A1W2P6J2
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: true
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Protein
Q3USN8
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: false
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Protein Domain
IPR018816 | Cactin_central
Type: Domain
Description: This entry represents the conserved central domain of cactin. It contains two of three predicted coiled-coil motifs. Most proteins containing this domain also have at the C-terminal end. Upstream of this domain in Drosophila proteins are a serine-rich region, some non-typical RD motifs and three predicted bipartite nuclear localisation signals, none of which are well-conserved.Cactin associates with IkappaB-cactus as one of the intracellular members of the Rel (NF-kappaB) pathway which is conserved in invertebrates and vertebrates. In mammals, this pathway controls the activities of the immune and inflammatory response genes as well as viral genes, and is critical for cell growth and survival. In Drosophila, the Rel pathway functions in the innate cellular and humoral immune response, in muscle development, and in the establishment of dorsal-ventral polarity in the early embryo [].
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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