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Search results 601 to 700 out of 734 for Ror2

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Type Details Score
Publication
30026494 | J:266265
First Author: Kishimoto K
Year: 2018
Journal: Nat Commun
Title: Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus.
Volume: 9
Issue: 1
Pages: 2816
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Publication
29428562 | J:260471
First Author: Gerhardt B
Year: 2018
Journal: Dev Biol
Title: Notum attenuates Wnt/β-catenin signaling to promote tracheal cartilage patterning.
Volume: 436
Issue: 1
Pages: 14-27
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Publication
22956684 | J:187747
First Author: Miyoshi H
Year: 2012
Journal: Science
Title: Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.
Volume: 338
Issue: 6103
Pages: 108-13
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Publication
20660756 | J:163602
First Author: Witte F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region.
Volume: 107
Issue: 32
Pages: 14211-6
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Publication
37873566 | J:343283
First Author: Russell NX
Year: 2023
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.
Volume: 325
Issue: 6
Pages: L788-L802
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Publication
31257105 | J:283040
First Author: McKenzie MG
Year: 2019
Journal: Neuron
Title: Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons.
Volume: 103
Issue: 5
Pages: 853-864.e4
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Publication
31226309 | J:281425
 
First Author: Nakaniwa M
Year: 2019
Journal: Gene Expr Patterns
Title: Primary cilia in murine palatal rugae development.
Volume: 34
Pages: 119062
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Publication
27321927 | J:239715
First Author: Galazo MJ
Year: 2016
Journal: Neuron
Title: Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.
Volume: 91
Issue: 1
Pages: 90-106
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Publication
21935430 | J:177881
First Author: Zhang Z
Year: 2011
Journal: PLoS One
Title: Fuz regulates craniofacial development through tissue specific responses to signaling factors.
Volume: 6
Issue: 9
Pages: e24608
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Publication
18480165 | J:136961
First Author: Zhang Y
Year: 2008
Journal: Development
Title: Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Volume: 135
Issue: 12
Pages: 2161-72
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Publication
15755804 | J:98216
First Author: García-García MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Analysis of mouse embryonic patterning and morphogenesis by forward genetics.
Volume: 102
Issue: 17
Pages: 5913-9
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Publication
35831952 | J:327818
 
First Author: Murphy P
Year: 2022
Journal: Development
Title: Integrated analysis of Wnt signalling system component gene expression.
Volume: 149
Issue: 16
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Publication
30022023 | J:266389
First Author: Yin W
Year: 2018
Journal: Nat Commun
Title: The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis.
Volume: 9
Issue: 1
Pages: 2815
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Publication
18351675 | J:122362
First Author: Harwood BN
Year: 2008
Journal: Dev Dyn
Title: Members of the WNT signaling pathways are widely expressed in mouse ovaries, oocytes, and cleavage stage embryos.
Volume: 237
Issue: 4
Pages: 1099-111
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Publication
21947380 | J:181586
First Author: Hald J
Year: 2012
Journal: Diabetologia
Title: Pancreatic islet and progenitor cell surface markers with cell sorting potential.
Volume: 55
Issue: 1
Pages: 154-65
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Publication
15963767 | J:103164
First Author: Minina E
Year: 2005
Journal: Gene Expr Patterns
Title: Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification.
Volume: 6
Issue: 1
Pages: 102-9
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Publication
21905163 | J:176660
First Author: Abler LL
Year: 2011
Journal: Dev Dyn
Title: A high-resolution molecular atlas of the fetal mouse lower urogenital tract.
Volume: 240
Issue: 10
Pages: 2364-77
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
25826454 | J:229257
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
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Publication
28705898 | J:243411
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
38975886 | J:357835
First Author: Benitz S
Year: 2024
Journal: Cancer Discov
Title: ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma.
Volume: 14
Issue: 11
Pages: 2162-2182
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8C3W2
Organism: Mus musculus/domesticus
Length: 944  
Fragment?: false
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Protein
E9PUN5
Organism: Mus musculus/domesticus
Length: 932  
Fragment?: false
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Pathway
R-MMU-5140745 | WNT5A-dependent internalization of FZD2, FZD5 and ROR2
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Publication
18667433 | -
First Author: Nomachi A
Year: 2008
Journal: J Biol Chem
Title: Receptor tyrosine kinase Ror2 mediates Wnt5a-induced polarized cell migration by activating c-Jun N-terminal kinase via actin-binding protein filamin A.
Volume: 283
Issue: 41
Pages: 27973-81
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Interaction Experiment
Oishi I (2003)
Description: The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.
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Interaction Experiment
Matsuda T (2003)
Description: The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.
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HT Experiment
GSE161395 | Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during root development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q9Z139
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
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Publication
12754255 | -
First Author: Matsuda T
Year: 2003
Journal: J Biol Chem
Title: The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.
Volume: 278
Issue: 31
Pages: 29057-64
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Protein Coding Gene
MGI:1347520 | Ror1
Type: protein_coding_gene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Ror2/Ror2<+>
Background: B6.129S1-Ror2
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0110969 | brachydactyly type B1
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Allele
Ror2<tm1Anec> | MGI:3793279
 
Name: receptor tyrosine kinase-like orphan receptor 2; targeted mutation 1, Aris N Economides
Allele Type: Targeted
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Allele
Ror2<tm1Ymi> | MGI:2183225
Name: receptor tyrosine kinase-like orphan receptor 2; targeted mutation 1, Yasuhiro Minami
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Prickle1<tm1Asw> | MGI:5645929
Name: prickle planar cell polarity protein 1; targeted mutation 1, Anand Swaroop
Allele Type: Targeted
Attribute String: Hypomorph, Reporter
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Publication
25835638 | -
First Author: Shabani M
Year: 2015
Journal: Expert Opin Ther Targets
Title: Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy.
Volume: 19
Issue: 7
Pages: 941-55
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Publication
21487037 | -
First Author: Gentile A
Year: 2011
Journal: Cancer Res
Title: Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis.
Volume: 71
Issue: 8
Pages: 3132-41
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Protein Domain
IPR016247 | Tyr_kinase_rcpt_ROR
Type: Family
Description: The Ror family of receptor tyrosine kinases consists of two structurally related proteins, Ror1 and Ror2. Ror1 is a pseudokinase that acts as a substrate for the oncogenic tyrosine kinase Met []. It is expressed during development []. It shows no significant expression in normal adult tissues, but it is selectively overexpressed in a number of malignancies []. Ror2 functions as a Wnt receptor required to maintain basal NMDAR-mediated synaptic transmission []. For a time its ligand remained elusive, hence the name receptor tyrosine kinase-like orphan receptor-2 (Ror2). It is now established that Wnt5A acts a ligand for Ror2 [].
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Genotype
Genotype
Symbol: Ror2/Ror2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ror2/Ror2
Background: B6.129S1-Ror2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prickle1/Prickle1
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prickle1/Prickle1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060764 | autosomal recessive Robinow syndrome
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Protein Coding Gene
MGI:108571 | Fzd5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1888513 | Fzd2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1921575 | Cltb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98958 | Wnt5a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9JIP6
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Protein
Q9EQD0
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
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Protein
Q6IRU5
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
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Protein
P22725
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein Coding Gene
MGI:1916034 | Prickle1
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
GSE140779 | A mammalian Wnt5a-Ror2-angl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
17942487 | -
First Author: Green JL
Year: 2007
Journal: Development
Title: The C. elegans ROR receptor tyrosine kinase, CAM-1, non-autonomously inhibits the Wnt pathway.
Volume: 134
Issue: 22
Pages: 4053-62
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Publication
18848778 | -
First Author: Green JL
Year: 2008
Journal: Trends Cell Biol
Title: Ror receptor tyrosine kinases: orphans no more.
Volume: 18
Issue: 11
Pages: 536-44
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Protein Domain
IPR041775 | Ror-like_CRD
Type: Domain
Description: The cysteine-rich domain (CRD) is an essential part of the tyrosine kinase-like orphan receptor (Ror) proteins, a conserved family of tyrosine kinases that function in various processes, including neuronal and skeletal development, cell polarity, and cell movement. Ror proteins are receptors of Wnt proteins, which are key players in a number of fundamental cellular processes in embryogenesis and postnatal development. In different cellular contexts, Ror proteins can either activate or repress transcription of Wnt target genes, and can modulate Wnt signaling by sequestering Wnt ligands. In addition, a number of Wnt-independent functions have been proposed for both Ror1 and Ror2 []. Proteins containing this domain also include CAM-1 from C. elegans. CAM-1 is a ROR receptor tyrosine kinase that inhibits the Wnt pathway [].
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Protein Coding Gene
MGI:1919020 | Ap2b1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388633 | Cltc
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1298405 | Ap2m1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:894297 | Clta
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
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