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Search results 601 to 700 out of 768 for Rorc

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Hits by Strain

Type Details Score
Strain
MGI:6476197 | C57BL/6JSmoc-Rorc<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Rorc-mCherry,-cre/ERT2)#Litt | MGI:7493594
Name: transgene insertion, Dan R Littman
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Recombinase, Reporter
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Allele
Rorc<em1(Thy1)Aben> | MGI:7518202
Name: RAR-related orphan receptor gamma; endonuclease-mediated mutation 1, Albert Bendelac
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: A930024E05Rik/A930024E05Rik Tg(Rorc-cre)1Litt/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bptf/Bptf Tg(Rorc-cre)1Litt/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
20142427 | J:158828
First Author: Satoh-Takayama N
Year: 2010
Journal: J Exp Med
Title: IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors.
Volume: 207
Issue: 2
Pages: 273-80
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Allele
Rorc<tm1Amj> | MGI:2386114
Name: RAR-related orphan receptor gamma; targeted mutation 1, Anton M Jetten
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
31628054 | J:282655
First Author: Chun E
Year: 2019
Journal: Immunity
Title: Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.
Volume: 51
Issue: 5
Pages: 871-884.e6
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Publication
33957945 | J:329598
First Author: Deng Y
Year: 2021
Journal: J Neuroinflammation
Title: Conditional knockout of Tsc1 in RORγt-expressing cells induces brain damage and early death in mice.
Volume: 18
Issue: 1
Pages: 107
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Publication
33852831 | J:305813
First Author: Huang J
Year: 2021
Journal: Immunity
Title: Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93.
Volume: 54
Issue: 4
Pages: 673-686.e4
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Publication
28701769 | J:257295
First Author: Suo C
Year: 2017
Journal: Sci Rep
Title: Perfluorooctane sulfonate affects intestinal immunity against bacterial infection.
Volume: 7
Issue: 1
Pages: 5166
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Publication
32092146 | J:299385
First Author: Kadekar D
Year: 2020
Journal: Eur J Immunol
Title: The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for γδT17 cell development, activation, or skin inflammation.
Volume: 50
Issue: 6
Pages: 873-879
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Publication
39004382 | J:358933
First Author: Karmoker JR
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Aryl hydrocarbon receptor (AhR)-mediated immune responses to degeneration of the retinal pigment epithelium.
Volume: 1870
Issue: 7
Pages: 167351
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Allele
Tg(Rorc-EGFP)1Ebe | MGI:3829387
Name: transgene insertion 1, Gerard Eberl
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6467246 | C57BL/6J-Rorc<em1Litt>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Rorc*-mCherry,-cre/ERT2)#Litt | MGI:7493596
Name: transgene insertion, Dan R Littman
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Recombinase, Reporter
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Strain
MGI:7518203 | C57BL/6J-Rorc<em1(Thy1)Aben>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Ltbr/Ltbr Tg(Rorc-cre)1Litt/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: A930024E05Rik/A930024E05Rik Satb1/Satb1 Tg(Rorc-cre)1Litt/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: A930024E05Rik/A930024E05Rik Bptf/Bptf Satb1/Satb1 Tg(Rorc-cre)1Litt/?
Background: involves: C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ltb/Ltb Tg(Rorc-cre)1Litt/?
Background: involves: C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
20962846 | J:165551
First Author: Ghoreschi K
Year: 2010
Journal: Nature
Title: Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling.
Volume: 467
Issue: 7318
Pages: 967-71
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HT Experiment
GSE239553 | A conserved transcriptional program for MAIT cells across mammalian evolution [Mmusculus_Colon_MAIT]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE239557 | A conserved transcriptional program for MAIT cells across mammalian evolution [Mmusculus_Ileum_MAIT]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE239555 | A conserved transcriptional program for MAIT cells across mammalian evolution [Mmusculus_MesLN_MAIT]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
23460741 | J:194814
First Author: Nakagawa R
Year: 2013
Journal: J Immunol
Title: Peyer's patch inducer cells play a leading role in the formation of B and T cell zone architecture.
Volume: 190
Issue: 7
Pages: 3309-18
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Publication
30374017 | J:271282
First Author: Filipovic I
Year: 2018
Journal: Nat Commun
Title: Molecular definition of group 1 innate lymphoid cells in the mouse uterus.
Volume: 9
Issue: 1
Pages: 4492
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Genotype
Genotype
Symbol: Rorc/Rorc
Background: either: (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * C57BL/6 * DBA/2)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Rorc-cre)1Litt/?
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rorc/Rorc
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cxxc1/Cxxc1 Tg(Rorc-cre)1Litt/?
Background: involves: 129 * C57BL/6J * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Rorc-EGFP)1Ebe/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Publication
23562159 | J:196163
First Author: Malhotra N
Year: 2013
Journal: Immunity
Title: A network of high-mobility group box transcription factors programs innate interleukin-17 production.
Volume: 38
Issue: 4
Pages: 681-93
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Publication
21151104 | J:167439
First Author: Lazarevic V
Year: 2011
Journal: Nat Immunol
Title: T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt.
Volume: 12
Issue: 1
Pages: 96-104
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Publication
31676672 | J:282185
First Author: Lo BC
Year: 2019
Journal: J Immunol
Title: The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection.
Volume: 203
Issue: 12
Pages: 3209-3215
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Publication
20471290 | J:160694
First Author: Mukasa R
Year: 2010
Journal: Immunity
Title: Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
Volume: 32
Issue: 5
Pages: 616-27
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Publication
30315140 | J:267734
First Author: Li B
Year: 2018
Journal: J Immunol
Title: IL-6 Promotes T Cell Proliferation and Expansion under Inflammatory Conditions in Association with Low-Level RORγt Expression.
Volume: 201
Issue: 10
Pages: 2934-2946
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Publication
26194464 | J:224448
 
First Author: Yoon JH
Year: 2015
Journal: Nat Commun
Title: Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation.
Volume: 6
Pages: 7600
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Publication
28555647 | J:244764
 
First Author: Hasan Z
Year: 2017
Journal: Nat Commun
Title: JunB is essential for IL-23-dependent pathogenicity of Th17 cells.
Volume: 8
Pages: 15628
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Publication
27111144 | J:259386
First Author: Xing S
Year: 2016
Journal: Nat Immunol
Title: Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity.
Volume: 17
Issue: 6
Pages: 695-703
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Publication
28338984 | J:250239
First Author: Matsui-Hasumi A
Year: 2017
Journal: Int Immunol
Title: E3 ubiquitin ligases SIAH1/2 regulate hypoxia-inducible factor-1 (HIF-1)-mediated Th17 cell differentiation.
Volume: 29
Issue: 3
Pages: 133-143
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Publication
22018472 | J:177860
First Author: Lu KT
Year: 2011
Journal: Immunity
Title: Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells.
Volume: 35
Issue: 4
Pages: 622-32
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Publication
28445726 | J:254520
First Author: Limagne E
Year: 2017
Journal: Cell Rep
Title: Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation.
Volume: 19
Issue: 4
Pages: 746-759
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Publication
26231117 | J:254628
First Author: Califano D
Year: 2015
Journal: Immunity
Title: Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells.
Volume: 43
Issue: 2
Pages: 354-68
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Publication
21600798 | J:172116
First Author: Ichiyama K
Year: 2011
Journal: Immunity
Title: Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.
Volume: 34
Issue: 5
Pages: 741-54
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Publication
32973810 | J:308197
 
First Author: Zhang Q
Year: 2020
Journal: Front Immunol
Title: Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Volume: 11
Pages: 2040
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Publication
27279370 | J:315918
First Author: Philips RL
Year: 2016
Journal: J Immunol
Title: HDAC3 Is Required for the Downregulation of RORγt during Thymocyte Positive Selection.
Volume: 197
Issue: 2
Pages: 541-54
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Publication
36026450 | J:327987
First Author: Chi X
Year: 2022
Journal: Sci Adv
Title: RORγt expression in mature TH17 cells safeguards their lineage specification by inhibiting conversion to TH2 cells.
Volume: 8
Issue: 34
Pages: eabn7774
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Publication
24913234 | J:214446
First Author: Kim TJ
Year: 2014
Journal: J Exp Med
Title: Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment.
Volume: 211
Issue: 7
Pages: 1421-31
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Publication
37429951 | J:356820
First Author: Shen X
Year: 2023
Journal: Nat Aging
Title: Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging.
Volume: 3
Issue: 8
Pages: 965-981
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Publication
31549795 | J:282095
First Author: Agerholm R
Year: 2019
Journal: EMBO Rep
Title: STAT3 but not STAT4 is critical for γδT17 cell responses and skin inflammation.
Volume: 20
Issue: 11
Pages: e48647
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Publication
23596287 | J:198457
First Author: Ivanov S
Year: 2013
Journal: J Virol
Title: Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection.
Volume: 87
Issue: 12
Pages: 6911-24
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Genotype
Genotype
Symbol: Foxp3/Foxp3 Tg(Rorc-EGFP)1Ebe/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il12rb1/Il12rb1 Tg(Rorc-EGFP)1Ebe/?
Background: involves: 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Rorc-cre)1Litt/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true
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Publication
26718978 | J:228871
First Author: Goldberg GL
Year: 2016
Journal: Am J Pathol
Title: G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis.
Volume: 186
Issue: 1
Pages: 172-84
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Publication
34107271 | J:321301
First Author: Wang X
Year: 2021
Journal: Immunity
Title: GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair.
Volume: 54
Issue: 6
Pages: 1123-1136.e8
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Publication
24759759 | J:215168
First Author: Burkhard SH
Year: 2014
Journal: PLoS One
Title: T cell contamination in flow cytometry gating approaches for analysis of innate lymphoid cells.
Volume: 9
Issue: 4
Pages: e94196
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Publication
36279426 | J:331529
First Author: Peng V
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription.
Volume: 119
Issue: 45
Pages: e2214900119
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Publication
31296736 | J:359134
First Author: Di Luccia B
Year: 2019
Journal: J Exp Med
Title: ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands.
Volume: 216
Issue: 10
Pages: 2231-2241
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Publication
38561332 | J:348971
First Author: Hao J
Year: 2024
Journal: Nat Commun
Title: Dysregulation of Wnt/β-catenin signaling contributes to intestinal inflammation through regulation of group 3 innate lymphoid cells.
Volume: 15
Issue: 1
Pages: 2820
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Publication
26524590 | J:227470
First Author: Cui Y
Year: 2015
Journal: J Clin Invest
Title: Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.
Volume: 125
Issue: 11
Pages: 4171-85
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Publication
34818549 | J:334441
First Author: Teng F
Year: 2021
Journal: Cell Rep
Title: ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Volume: 37
Issue: 8
Pages: 110051
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Publication
21789181 | J:175775
First Author: Taube C
Year: 2011
Journal: PLoS One
Title: IL-22 is produced by innate lymphoid cells and limits inflammation in allergic airway disease.
Volume: 6
Issue: 7
Pages: e21799
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Publication
18231598 | J:131548
First Author: Egawa T
Year: 2008
Journal: PLoS One
Title: Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.
Volume: 3
Issue: 1
Pages: e1512
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Publication
37540734 | J:358469
First Author: Chiaranunt P
Year: 2023
Journal: Sci Immunol
Title: Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling.
Volume: 8
Issue: 86
Pages: eabq4573
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Publication
23842754 | J:205697
First Author: Tan Z
Year: 2013
Journal: J Immunol
Title: IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation.
Volume: 191
Issue: 4
Pages: 1835-44
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Publication
31633019 | J:288079
First Author: Lin F
Year: 2019
Journal: Sci Adv
Title: Epigenetic initiation of the TH17 differentiation program is promoted by Cxxc finger protein 1.
Volume: 5
Issue: 10
Pages: eaax1608
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Publication
29127150 | J:252648
First Author: Wheaton JD
Year: 2017
Journal: J Immunol
Title: Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.
Volume: 199
Issue: 12
Pages: 3931-3936
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Publication
30287480 | J:269365
First Author: Malhotra N
Year: 2018
Journal: J Exp Med
Title: SOX4 controls invariant NKT cell differentiation by tuning TCR signaling.
Volume: 215
Issue: 11
Pages: 2887-2900
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Publication
28991267 | J:259000
First Author: Rouxel O
Year: 2017
Journal: Nat Immunol
Title: Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes.
Volume: 18
Issue: 12
Pages: 1321-1331
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Allele
Rorc<m1Btlr> | MGI:5523975
 
Name: RAR-related orphan receptor gamma; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Genotype
Genotype
Symbol: Ccr6/Ccr6 Tg(Rorc-EGFP)1Ebe/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Il6/Il6 Tg(Rorc-EGFP)1Ebe/?
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc<+> Tg(Rorc-EGFP)1Ebe/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tet1/Tet1 Tet2/Tet2 Tet3/Tet3 Tg(Rorc-cre)1Litt/?
Background: involves: 129 * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tet1/Tet1 Tet2/Tet2<+> Tet3/Tet3 Tg(Rorc-cre)1Litt/?
Background: involves: 129 * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rora/Rora Rorc/Rorc
Background: involves: 129 * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Rorc/Rorc<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
18454201 | J:319841
First Author: Liu AC
Year: 2008
Journal: PLoS Genet
Title: Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms.
Volume: 4
Issue: 2
Pages: e1000023
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Publication
37662923 | J:340323
 
First Author: Ishikawa J
Year: 2023
Journal: Front Immunol
Title: IL-21 is required for the maintenance and pathogenesis of murine Vγ4(+) IL-17-producing γδT cells.
Volume: 14
Pages: 1211620
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Publication
35113015 | J:327458
   
First Author: Wang X
Year: 2022
Journal: Elife
Title: Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms.
Volume: 11
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Publication
19846871 | J:157183
First Author: Satoh-Takayama N
Year: 2009
Journal: J Immunol
Title: The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium.
Volume: 183
Issue: 10
Pages: 6579-87
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Publication
25136117 | J:214819
First Author: Watanabe Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Volume: 111
Issue: 35
Pages: 12829-34
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Publication
26968344 | J:232052
First Author: Hao W
Year: 2016
Journal: Am J Pathol
Title: Deficiency of IκB Kinase β in Myeloid Cells Reduces Severity of Experimental Autoimmune Encephalomyelitis.
Volume: 186
Issue: 5
Pages: 1245-57
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Publication
33390832 | J:354858
First Author: Chen S
Year: 2021
Journal: Int J Biol Sci
Title: Eomesodermin in CD4(+)T cells is essential for Ginkgolide K ameliorating disease progression in experimental autoimmune encephalomyelitis.
Volume: 17
Issue: 1
Pages: 50-61
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Publication
27514477 | J:240320
First Author: Dhawan S
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity.
Volume: 311
Issue: 5
Pages: G920-G933
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Publication
21807912 | J:176002
First Author: Werner JL
Year: 2011
Journal: Infect Immun
Title: Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.
Volume: 79
Issue: 10
Pages: 3966-77
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Publication
34925309 | J:319364
 
First Author: Murayama MA
Year: 2021
Journal: Front Immunol
Title: The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation.
Volume: 12
Pages: 607346
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Publication
24249741 | J:211841
First Author: Zhao P
Year: 2014
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