|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 601 to 684 out of 684 for Rtl1

<< First    < Previous  |  Next >    Last >>
0.044s

Categories

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:8261132
Assay Type: Immunohistochemistry
Annotation Date: 2025-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3815227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:8261364
Age: postnatal day 0
Image: 2d
Specimen Label: 2d
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
25607839 | J:220387
First Author: Chandler RJ
Year: 2015
Journal: J Clin Invest
Title: Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.
Volume: 125
Issue: 2
Pages: 870-80
•
•
•
•
•
Publication
35513363 | J:324246
First Author: Van de Pette M
Year: 2022
Journal: Nat Commun
Title: Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Volume: 13
Issue: 1
Pages: 2464
•
•
•
•
•
Publication
19194500 | J:146496
First Author: Hagan JP
Year: 2009
Journal: PLoS One
Title: At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1.
Volume: 4
Issue: 2
Pages: e4352
•
•
•
•
•
Publication
20610486 | J:166176
First Author: Zhou Y
Year: 2010
Journal: Development
Title: Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene.
Volume: 137
Issue: 16
Pages: 2643-52
•
•
•
•
•
Publication
19264764 | J:147577
First Author: Takahashi N
Year: 2009
Journal: Hum Mol Genet
Title: Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.
Volume: 18
Issue: 10
Pages: 1879-88
•
•
•
•
•
Publication
27904015 | J:241393
First Author: Saito T
Year: 2017
Journal: J Reprod Dev
Title: Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice.
Volume: 63
Issue: 1
Pages: 101-109
•
•
•
•
•
Publication
29931170 | J:266963
First Author: Saito T
Year: 2018
Journal: Hum Mol Genet
Title: A tandem repeat array in IG-DMR is essential for imprinting of paternal allele at the Dlk1-Dio3 domain during embryonic development.
Volume: 27
Issue: 18
Pages: 3283-3292
•
•
•
•
•
Publication
37372444 | J:344890
 
First Author: Zhang L
Year: 2023
Journal: Genes (Basel)
Title: Meg8-DMR as the Secondary Regulatory Region Regulates the Expression of MicroRNAs While It Does Not Affect Embryonic Development in Mice.
Volume: 14
Issue: 6
•
•
•
•
•
Publication
23195472 | J:192572
First Author: Qu C
Year: 2013
Journal: Gene Expr Patterns
Title: Gene expression and IG-DMR hypomethylation of maternally expressed gene 3 in developing corticospinal neurons.
Volume: 13
Issue: 1-2
Pages: 51-6
•
•
•
•
•
Publication
28934383 | J:251670
First Author: Kumamoto S
Year: 2017
Journal: Hum Mol Genet
Title: Overexpression of microRNAs from the Gtl2-Rian locus contributes to postnatal death in mice.
Volume: 26
Issue: 19
Pages: 3653-3662
•
•
•
•
•
Publication
31301299 | J:281273
First Author: Zhu W
Year: 2019
Journal: Dev Biol
Title: Meg3-DMR, not the Meg3 gene, regulates imprinting of the Dlk1-Dio3 locus.
Volume: 455
Issue: 1
Pages: 10-18
•
•
•
•
•
Publication
31882978 | J:287095
First Author: Hara S
Year: 2019
Journal: Sci Rep
Title: Efficient production and transmission of CRISPR/Cas9-mediated mutant alleles at the IG-DMR via generation of mosaic mice using a modified 2CC method.
Volume: 9
Issue: 1
Pages: 20202
•
•
•
•
•
Publication
18854139 | J:143283
First Author: Li X
Year: 2008
Journal: Dev Cell
Title: A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.
Volume: 15
Issue: 4
Pages: 547-57
•
•
•
•
•
Publication
15716091 | J:96508
First Author: Brandt J
Year: 2005
Journal: Gene
Title: Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.
Volume: 345
Issue: 1
Pages: 101-11
•
•
•
•
•
Publication
16575184 | J:108133
First Author: Sekita Y
Year: 2006
Journal: Cytogenet Genome Res
Title: Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.
Volume: 113
Issue: 1-4
Pages: 223-9
•
•
•
•
•
Publication
39382697 | J:360327
First Author: Yu H
Year: 2024
Journal: Cell Mol Life Sci
Title: Silencing of maternally expressed RNAs in Dlk1-Dio3 domain causes fatal vascular injury in the fetal liver.
Volume: 81
Issue: 1
Pages: 429
•
•
•
•
•
Publication
16093683 | J:105407
First Author: Brandt J
Year: 2005
Journal: Cytogenet Genome Res
Title: A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.
Volume: 110
Issue: 1-4
Pages: 307-17
•
•
•
•
•
Publication
26487685 | J:227271
First Author: Gao YQ
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance.
Volume: 112
Issue: 44
Pages: 13627-32
•
•
•
•
•
Publication
34559199 | J:311930
 
First Author: Shiura H
Year: 2021
Journal: Development
Title: PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta.
Volume: 148
Issue: 19
•
•
•
•
•
Publication
16309881 | J:105770
First Author: Tierling S
Year: 2006
Journal: Genomics
Title: High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12.
Volume: 87
Issue: 2
Pages: 225-35
•
•
•
•
•
Publication
17901046 | J:132025
First Author: Labialle S
Year: 2008
Journal: Hum Mol Genet
Title: Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes.
Volume: 17
Issue: 1
Pages: 15-26
•
•
•
•
•
Publication
16575173 | J:108137
First Author: Fukasawa M
Year: 2006
Journal: Cytogenet Genome Res
Title: Genomic imprinting in Dicer1-hypomorphic mice.
Volume: 113
Issue: 1-4
Pages: 138-43
•
•
•
•
•
Publication
19762426 | J:153616
First Author: Gabory A
Year: 2009
Journal: Development
Title: H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.
Volume: 136
Issue: 20
Pages: 3413-21
•
•
•
•
•
Publication
38521877 | J:346630
First Author: Zhang X
Year: 2024
Journal: Commun Biol
Title: Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature.
Volume: 7
Issue: 1
Pages: 363
•
•
•
•
•
Publication
23139813 | J:195360
First Author: Seibt J
Year: 2012
Journal: PLoS One
Title: Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon.
Volume: 7
Issue: 11
Pages: e48675
•
•
•
•
•
Publication
23085235 | J:192195
First Author: Himes KP
Year: 2013
Journal: Dev Biol
Title: Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.
Volume: 373
Issue: 1
Pages: 72-82
•
•
•
•
•
Publication
22326222 | J:182286
First Author: Charalambous M
Year: 2012
Journal: Cell Metab
Title: Imprinted gene dosage is critical for the transition to independent life.
Volume: 15
Issue: 2
Pages: 209-21
•
•
•
•
•
Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
•
•
•
•
•
Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Transgene
MGI:4821094 | Tg(Ins1-Tag,-luc)1Gcr
Type: transgene
Organism: mouse, laboratory
•
•
•
•
•
Publication
17216273 | -
First Author: Leeton LA
Year: 2007
Journal: Funct Integr Genomics
Title: Adipogenesis in mouse 3T3L1 cells: the effects of Rtl1 over-expression.
Volume: 7
Issue: 3
Pages: 257-61
•
•
•
•
•
Publication
34357660 | -
First Author: Zurowska K
Year: 2022
Journal: Proteins
Title: Structural evidence that MOAP1 and PEG10 are derived from retrovirus/retrotransposon Gag proteins.
Volume: 90
Issue: 1
Pages: 309-313
•
•
•
•
•
Protein Domain
IPR063300 | PEG10-RTL1_C-capsid
Type: Domain
Description: This is a domain found in a group of retrotransposon-derived proteins from animals, including PEG10, RTL1 and retrotransposon Gag-like 3/5/6. PEG10 binds its own mRNA and self-assembles into virion-like capsids [, ]. RTL1 plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta []. RTL3 plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal []. This entry represents the C-terminal capsid-like domain.
•
•
•
•
•
Protein Domain
IPR063610 | PRO_PEG10-RTL1
Type: Domain
Description: This entry represents the protease (PRO) domain of eukaryotic retrotransposon-derived proteins from the Mart family, RTL1 and PEG10 []. Mammal RTL1 plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta. PEG10 is a retrotransposon-derived protein that binds its own mRNA and self-assembles into virion-like capsids that are released from cells, enabling intercellular transfer of PEG10 mRNA [].
•
•
•
•
•
Allele
Igdmr<tm1Ace> | MGI:3051685
Name: intergenic germline-derived differentially methylated region; targeted mutation 1, Anatomy Cambridge England
Allele Type: Targeted
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:7571082 | 129-Dpysl5<tm1Gosh>/Orl
Attribute String: coisogenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:6750903 | B6;129P2-Igdmr<tm1Ace>/H
Attribute String: targeted mutation, mutant stock
•
•
•
•
•
Publication
17959172 | J:127743
First Author: Kawahara M
Year: 2007
Journal: FEBS Lett
Title: Appropriate expression of imprinted genes on mouse chromosome 12 extends development of bi-maternal embryos to term.
Volume: 581
Issue: 27
Pages: 5178-84
•
•
•
•
•
Publication
17166925 | J:117031
First Author: Lin SP
Year: 2007
Journal: Development
Title: Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region.
Volume: 134
Issue: 2
Pages: 417-26
•
•
•
•
•
Genotype
Genotype
Symbol: Igdmr/Igdmr<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Protein
Q32KG4
Organism: Mus musculus/domesticus
Length: 1339  
Fragment?: false
•
•
•
•
•
Publication
34413232 | J:314915
First Author: Segel M
Year: 2021
Journal: Science
Title: Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.
Volume: 373
Issue: 6557
Pages: 882-889
•
•
•
•
•
Publication
19380578 | J:151215
First Author: Kawahara M
Year: 2009
Journal: J Biol Chem
Title: Defining contributions of paternally methylated imprinted genes at the Igf2-H19 and Dlk1-Gtl2 domains to mouse placentation by transcriptomic analysis.
Volume: 284
Issue: 26
Pages: 17751-65
•
•
•
•
•
Publication
27446912 | J:241039
 
First Author: Alonso-Martin S
Year: 2016
Journal: Front Cell Dev Biol
Title: Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis.
Volume: 4
Pages: 58
•
•
•
•
•
Protein
Q5DTT4
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: false
•
•
•
•
•
Protein
Q8C065
Organism: Mus musculus/domesticus
Length: 599  
Fragment?: false
•
•
•
•
•
Publication
26165924 | J:322449
First Author: Zhong C
Year: 2015
Journal: Cell Stem Cell
Title: CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library.
Volume: 17
Issue: 2
Pages: 221-32
•
•
•
•
•
Protein
F6TUF7
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
•
•
•
•
•
Protein
F6VWQ4
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
•
•
•
•
•
Protein
Q9D1F0
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
•
•
•
•
•
Protein
Q9D6I0
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
•
•
•
•
•
Protein Domain
IPR032549 | RTL1/1-8/LDOC_capsid-like
Type: Domain
Description: This domain is found in some members of the Mart (mammalian retrotransposon-derived) family, including LDOC1/Mart7, LDOC1L/Mart6, RTL1/Mart1, RTL3-8 [, ]. LDOC1 is a MZF-1-interacting protein, inhibits NF-kappaB activation and relates with cancer and some other diseases [, , , ]. LDOC1 is a small protein and this entry covers almost its full length. In RTL proteins, it represents the N-terminal capsid-like domain. RTL1 plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta []. RTL3 plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal [].
•
•
•
•
•
Publication
30311912 | J:290593
   
First Author: Yen YP
Year: 2018
Journal: Elife
Title: Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity.
Volume: 7
•
•
•
•
•
Publication
20530553 | J:162648
First Author: Zumsteg A
Year: 2010
Journal: Carcinogenesis
Title: A bioluminescent mouse model of pancreatic {beta}-cell carcinogenesis.
Volume: 31
Issue: 8
Pages: 1465-74
•
•
•
•
•
Protein
Q7M732
Organism: Mus musculus/domesticus
Length: 1744  
Fragment?: false
•
•
•
•
•
Protein
B4YB44
Organism: Mus musculus/domesticus
Length: 1744  
Fragment?: false
•
•
•
•
•
Publication
25888968 | -
 
First Author: Henke C
Year: 2015
Journal: Retrovirology
Title: Selective expression of sense and antisense transcripts of the sushi-ichi-related retrotransposon--derived family during mouse placentogenesis.
Volume: 12
Pages: 9
•
•
•
•
•
Publication
16155747 | -
First Author: Youngson NA
Year: 2005
Journal: J Mol Evol
Title: A small family of sushi-class retrotransposon-derived genes in mammals and their relation to genomic imprinting.
Volume: 61
Issue: 4
Pages: 481-90
•
•
•
•
•
Protein
Q505G4
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: false
•
•
•
•
•
Protein
Q7TPY9
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: false
•
•
•
•
•
Publication
10403563 | -
First Author: Nagasaki K
Year: 1999
Journal: Cancer Lett
Title: Identification of a novel gene, LDOC1, down-regulated in cancer cell lines.
Volume: 140
Issue: 1-2
Pages: 227-34
•
•
•
•
•
Publication
12712434 | -
First Author: Nagasaki K
Year: 2003
Journal: Int J Cancer
Title: Leucine-zipper protein, LDOC1, inhibits NF-kappaB activation and sensitizes pancreatic cancer cells to apoptosis.
Volume: 105
Issue: 4
Pages: 454-8
•
•
•
•
•
Publication
21547351 | -
First Author: Salemi M
Year: 2011
Journal: Hum Cell
Title: Over?expression of LDOC1 and PARP1, two pro-apoptotic genes, in a patient with cryptorchidism and DiGeorge anomaly.
Volume: 24
Issue: 2
Pages: 112-3
•
•
•
•
•
Publication
21310924 | -
First Author: Duzkale H
Year: 2011
Journal: Blood
Title: LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.
Volume: 117
Issue: 15
Pages: 4076-84
•
•
•
•
•
Protein
Q6P1Y1
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
•
•
•
•
•
Protein
Q7TN75
Organism: Mus musculus/domesticus
Length: 958  
Fragment?: false
•
•
•
•
•
Protein
H3BJQ1
Organism: Mus musculus/domesticus
Length: 604  
Fragment?: false
•
•
•
•
•
Protein
Q32KG6
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom