Type |
Details |
Score |
Allele |
Name: |
transgene insertion 14, Alan Remaley |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion B2614, Edward M Rubin |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant strain, coisogenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Vaisman B |
Year: |
2010 |
Journal: |
Circulation |
Title: |
Abstract 18091: Role of Endothelial Expression of ABCA1 and SR-BI Genes in HDL Metabolism, Cholesterol Trafficking and Protection Against Atherosclerosis |
|
|
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Nicholson AC |
Year: |
2000 |
Journal: |
Ann N Y Acad Sci |
Title: |
CD36 in atherosclerosis. The role of a class B macrophage scavenger receptor. |
Volume: |
902 |
|
Pages: |
128-31; discussion 131-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin X |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
SNMP is a signaling component required for pheromone sensitivity in Drosophila. |
Volume: |
105 |
Issue: |
31 |
Pages: |
10996-1001 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fluiter K |
Year: |
1997 |
Journal: |
Biochem J |
Title: |
Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells. |
Volume: |
326 ( Pt 2) |
|
Pages: |
515-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dao Thi VL |
Year: |
2011 |
Journal: |
Expert Rev Mol Med |
Title: |
Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation. |
Volume: |
13 |
|
Pages: |
e13 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes platelet glycoprotein 4 (CD36) and scavenger receptor class B member 1 (SCARB1, also known as CD36 antigen-like 1) from humans, and sensory neuron membrane protein 1 (SNMP1) from flies. CD36 is a a scavenger receptor important for lipoprotein binding and uptake of cholesterol and lipids in vertebrates []. SCARB1 plays an important role in the uptake of HDL cholesteryl ester []. It acts as a receptor for hepatitis C virus in hepatocytes [].SNMP1 is a homologue of CD36. SNMP1 has a role in detection and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Wyngene L |
Year: |
2021 |
Journal: |
iScience |
Title: |
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation. |
Volume: |
24 |
Issue: |
7 |
Pages: |
102790 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
509
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Byun S |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. |
Volume: |
294 |
Issue: |
22 |
Pages: |
8732-8744 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scherler L |
Year: |
2022 |
Journal: |
Biomolecules |
Title: |
Adenine-Induced Nephropathy Reduces Atherosclerosis in ApoE Knockout Mice. |
Volume: |
12 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Fan J |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. |
Volume: |
112 |
Issue: |
23 |
Pages: |
7261-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hueso M |
Year: |
2022 |
Journal: |
Biomed Pharmacother |
Title: |
MiR-125b downregulates macrophage scavenger receptor type B1 and reverse cholesterol transport. |
Volume: |
146 |
|
Pages: |
112596 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
133
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
446
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
66
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Trenteseaux C |
Year: |
2017 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids. |
Volume: |
37 |
Issue: |
11 |
Pages: |
2053-2063 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andres SF |
Year: |
2015 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. |
Volume: |
308 |
Issue: |
2 |
Pages: |
G100-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uemura Y |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung. |
Volume: |
12 |
Issue: |
11 |
Pages: |
e0187286 |
|
•
•
•
•
•
|