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Search results 601 to 700 out of 790 for Ski

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Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Publication
21844226 | J:178174
First Author: Matsumoto A
Year: 2011
Journal: Mol Cell Biol
Title: Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice.
Volume: 31
Issue: 20
Pages: 4176-92
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Publication
23648511 | J:199593
First Author: Huber K
Year: 2013
Journal: Dev Biol
Title: The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.
Volume: 380
Issue: 2
Pages: 286-98
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Publication
15075292 | J:89228
First Author: Chen MH
Year: 2004
Journal: Genes Dev
Title: Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.
Volume: 18
Issue: 6
Pages: 641-59
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Publication
15878163 | J:99789
First Author: Tang J
Year: 2005
Journal: FEBS Lett
Title: The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62.
Volume: 579
Issue: 13
Pages: 2883-90
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Publication
34473197 | J:314220
 
First Author: Xu H
Year: 2021
Journal: J Exp Med
Title: Arkadia-SKI/SnoN signaling differentially regulates TGF-β-induced iTreg and Th17 cell differentiation.
Volume: 218
Issue: 11
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Publication
32533074 | J:293844
First Author: Leonards K
Year: 2020
Journal: Nat Commun
Title: Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia.
Volume: 11
Issue: 1
Pages: 2807
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Publication
32601467 | J:299150
First Author: Laidlaw BJ
Year: 2020
Journal: Nat Immunol
Title: The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development.
Volume: 21
Issue: 9
Pages: 1082-1093
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Protein Coding Gene
MGP_CAROLIEiJ_G0018735 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_CAROLIEiJ_G0021477 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020778 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0023591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023553 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023558 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020524 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023318 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2679923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1099835 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020588 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023391 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020617 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023414 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022878 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015814 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_PahariEiJ_G0020472 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019618 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein Coding Gene
MGP_SPRETEiJ_G0022382 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:1968688
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:4828084
Age: embryonic day 14.5
Image: euxassay_007039_10
Specimen Label: euxassay_007039_10
Detected: true
Specimen Num: 1
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Publication
22427331 | -
First Author: Brockschmidt A
Year: 2012
Journal: Brain
Title: KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Volume: 135
Issue: Pt 4
Pages: 1027-41
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Publication
16183838 | -
First Author: Chen X
Year: 2005
Journal: Plant Physiol
Title: Mutation of the RESURRECTION1 locus of Arabidopsis reveals an association of cuticular wax with embryo development.
Volume: 139
Issue: 2
Pages: 909-19
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Publication
31076735 | -
First Author: Li T
Year: 2019
Journal: Nat Plants
Title: A genetics screen highlights emerging roles for CPL3, RST1 and URT1 in RNA metabolism and silencing.
Volume: 5
Issue: 5
Pages: 539-550
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Publication
31291246 | J:277331
First Author: Sah RK
Year: 2019
Journal: PLoS One
Title: Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.
Volume: 14
Issue: 7
Pages: e0213702
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Publication
35165395 | J:338083
First Author: Hwang I
Year: 2022
Journal: Mol Psychiatry
Title: Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.
Volume: 27
Issue: 4
Pages: 2030-2041
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Protein
Q3TP96
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Protein
D3YYG2
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
B2X2D9
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
A0A286YCU6
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: true
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Protein
A2A953
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: true
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Protein
Q9QYB2
Organism: Mus musculus/domesticus
Length: 751  
Fragment?: false
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Protein
Q925Q8
Organism: Mus musculus/domesticus
Length: 634  
Fragment?: false
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Protein
A2AKG8
Organism: Mus musculus/domesticus
Length: 1798  
Fragment?: false
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Protein
Q68G54
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: true
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Protein
Z4YN47
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: true
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Protein
Q78E91
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
E9PYJ6
Organism: Mus musculus/domesticus
Length: 1712  
Fragment?: false
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Protein
Z4YLL5
Organism: Mus musculus/domesticus
Length: 65  
Fragment?: true
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Protein
Q3UTV2
Organism: Mus musculus/domesticus
Length: 673  
Fragment?: false
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Publication
15107821 | -
First Author: Suzuki H
Year: 2004
Journal: Oncogene
Title: c-Ski inhibits the TGF-beta signaling pathway through stabilization of inactive Smad complexes on Smad-binding elements.
Volume: 23
Issue: 29
Pages: 5068-76
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Publication
21855801 | -
First Author: Lubas M
Year: 2011
Journal: Mol Cell
Title: Interaction profiling identifies the human nuclear exosome targeting complex.
Volume: 43
Issue: 4
Pages: 624-37
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Publication
19745809 | J:154718
First Author: Pan D
Year: 2009
Journal: EMBO J
Title: SnoN functions as a tumour suppressor by inducing premature senescence.
Volume: 28
Issue: 22
Pages: 3500-13
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Protein Domain
IPR023216 | Tscrpt_reg_SKI_SnoN
Type: Family
Description: This entry represents the SKI/SnoN family of proteins, which are the products of the oncogenic sno gene. This gene was identified based on its homology to v-ski, the transforming component of the Sloan-Kettering virus. Both Ski and SnoN are potent negative regulators of TGF-beta []. Overexpression of Ski or SnoN results in oncogenic transformation of avian fibroblasts; however it may also result in terminal differentiation and therefore the Ski/SnoN mechanism of action is thought to be complex [].These proteins do not have catalytic or DNA-binding activity and therefore function primarily through interaction with other proteins, acting as transcriptional cofactors. Despite their lack of DNA-binding ability, their primary function is related to transcriptional regulation, in particular the negative regulation of TGF-beta signalling [, ]. Ski/SnoN interact concurrently with co-Smad and R-Smad and in doing so block the ability of the Smad complexes to activate transcription of the TGF-beta target genes []. Binding of Ski/SnoN may additionally stabilise the Smad heteromer on DNA, therefore preventing further binding of active Smad complexes []. As Smad complexes critically mediate the inhibitory signals of TGF-beta in epithelial cells, high levels of SKI/SnoN may promote cell proliferation. They repress gene transcription recruiting diverse corepressors and histone deacetylases and stablish cross-regulatory mechanisms with TGF-beta/Smad pathway that control the magnitude and duration of TGF-beta signals. The alteration in regulatory processes may lead to disease development [].High levels of SnoN have been shown to stabilise p53 with a resultant increase in premature senescence. SnoN interacts with the PML protein and is then recruited to the PML nuclear bodies, resulting in stabilisation of p53 and premature senescence [].
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Publication
9915577 | J:51920
First Author: Caubit X
Year: 1999
Journal: Dev Dyn
Title: Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud.
Volume: 214
Issue: 1
Pages: 66-80
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Publication
10502109 | J:52628
First Author: Davis RJ
Year: 1999
Journal: Dev Genes Evol
Title: Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs.
Volume: 209
Issue: 9
Pages: 526-36
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Publication
12112469 | J:76916
First Author: Ferrer-Martínez A
Year: 2002
Journal: Dev Dyn
Title: Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development.
Volume: 224
Issue: 2
Pages: 154-67
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Publication
11231286 | J:67956
First Author: Minakuchi M
Year: 2001
Journal: Eur J Biochem
Title: Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.
Volume: 268
Issue: 5
Pages: 1340-51
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Publication
32859726 | J:301515
First Author: Huang X
Year: 2020
Journal: J Immunol
Title: IL-21 Promotes Intestinal Memory IgA Responses.
Volume: 205
Issue: 7
Pages: 1944-1952
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Publication
35763220 | J:350253
First Author: Su H
Year: 2022
Journal: Br J Pharmacol
Title: Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Volume: 179
Issue: 20
Pages: 4778-4791
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Publication
35491240 | J:350231
First Author: Wang L
Year: 2022
Journal: Br J Pharmacol
Title: Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Volume: 179
Issue: 17
Pages: 4423-4439
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Publication
33591571 | J:340430
First Author: Que Y
Year: 2021
Journal: Br J Pharmacol
Title: Inactivation of SERCA2 Cys(674) accelerates aortic aneurysms by suppressing PPARγ.
Volume: 178
Issue: 11
Pages: 2305-2323
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Publication
35413056 | J:324022
First Author: Autio A
Year: 2022
Journal: PLoS One
Title: SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.
Volume: 17
Issue: 4
Pages: e0266566
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Publication
10811619 | J:62174
First Author: Shinagawa T
Year: 2000
Journal: EMBO J
Title: The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice.
Volume: 19
Issue: 10
Pages: 2280-91
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Publication
24920669 | J:216004
First Author: Thompson MD
Year: 2014
Journal: J Biol Chem
Title: Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery.
Volume: 289
Issue: 29
Pages: 19907-16
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Publication
22567107 | J:187264
First Author: Hneino M
Year: 2012
Journal: PLoS One
Title: The TGF-β/Smad repressor TG-interacting factor 1 (TGIF1) plays a role in radiation-induced intestinal injury independently of a Smad signaling pathway.
Volume: 7
Issue: 5
Pages: e35672
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Publication
32035136 | J:288250
 
First Author: Que Y
Year: 2020
Journal: J Mol Cell Cardiol
Title: Inactivation of cysteine 674 in the SERCA2 accelerates experimental aortic aneurysm.
Volume: 139
Pages: 213-224
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Publication
31758704 | J:308616
First Author: Liu G
Year: 2020
Journal: Br J Pharmacol
Title: Inactivation of Cys674 in SERCA2 increases BP by inducing endoplasmic reticulum stress and soluble epoxide hydrolase.
Volume: 177
Issue: 8
Pages: 1793-1805
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Publication
3026737 | J:8563
First Author: Chaganti RS
Year: 1986
Journal: Cytogenet Cell Genet
Title: The cellular homologue of the transforming gene of SKV avian retrovirus maps to human chromosome region 1q22----q24.
Volume: 43
Issue: 3-4
Pages: 181-6
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Publication
28652077 | J:269897
First Author: Ji X
Year: 2017
Journal: Biochim Biophys Acta Gen Subj
Title: Vitamin C deficiency exacerbates diabetic glomerular injury through activation of transforming growth factor-β signaling.
Volume: 1861
Issue: 9
Pages: 2186-2195
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Publication
14656967 | J:86796
First Author: Xie T
Year: 2003
Journal: Genome Res
Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.
Volume: 13
Issue: 12
Pages: 2621-36
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Protein
Q60665
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
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Protein
Q60979
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: false
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Protein
Q3TRA0
Organism: Mus musculus/domesticus
Length: 369  
Fragment?: false
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Protein
Q3TQJ9
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: true
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Protein
D3Z7C5
Organism: Mus musculus/domesticus
Length: 549  
Fragment?: false
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Protein
Q3TB81
Organism: Mus musculus/domesticus
Length: 629  
Fragment?: false
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Publication
38025786 | J:343072
First Author: Vermeiren S
Year: 2023
Journal: iScience
Title: Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.
Volume: 26
Issue: 12
Pages: 108364
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Publication
18799476 | J:138839
First Author: Fulp CT
Year: 2008
Journal: Hum Mol Genet
Title: Identification of Arx transcriptional targets in the developing basal forebrain.
Volume: 17
Issue: 23
Pages: 3740-60
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Publication
30529950 | J:280142
 
First Author: Quintana-Urzainqui I
Year: 2018
Journal: iScience
Title: Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.
Volume: 10
Pages: 171-191
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Protein
Q80YR3
Organism: Mus musculus/domesticus
Length: 822  
Fragment?: false
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Protein
G3X9M2
Organism: Mus musculus/domesticus
Length: 909  
Fragment?: false
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Publication
25260714 | J:225781
 
First Author: Mei Y
Year: 2014
Journal: J Mol Cell Cardiol
Title: Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 promotes ischemia- and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage function.
Volume: 76
Pages: 275-82
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Protein
F8VPK0
Organism: Mus musculus/domesticus
Length: 1563  
Fragment?: false
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Protein
Q3UYZ5
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom