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Search results 601 to 700 out of 998 for Snca

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7707900
Age: embryonic day 14.5
Specimen Label: 3C
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7707900
Age: embryonic day 16.5
Specimen Label: 3D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3561127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7707900
Age: postnatal day 0
Specimen Label: 3K
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3561122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7707900
Age: embryonic day 14.5
Specimen Label: not shown
Detected: true
Specimen Num: 48
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3561124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7707900
Age: embryonic day 16.5
Specimen Label: not shown
Detected: true
Specimen Num: 49
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3561126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7707900
Age: embryonic day 18.5
Specimen Label: not shown
Detected: true
Specimen Num: 50
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GXD Expression
GXD Expression
   
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3561127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7707900
Age: postnatal day 0
Specimen Label: not shown
Detected: true
Specimen Num: 51
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GXD Expression
GXD Expression
 
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3677722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7707900
Age: embryonic day 14.5
Note: The cortical regions were also lightly stained.
Specimen Label: 4F
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3677722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7707900
Age: embryonic day 14.5
Note: Expressed in the cerebellum external germinative cell layer.
Specimen Label: not shown
Detected: true
Specimen Num: 48
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GXD Expression
GXD Expression
 
Probe: MGI:7707868
Assay Type: Immunohistochemistry
Annotation Date: 2024-08-08
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3791722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7707900
Age: embryonic day 14.5
Note: Very low expression in the granule and glomerular layers.
Specimen Label: not shown
Detected: true
Specimen Num: 48
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Publication
19004816 | J:147239
First Author: Inglis KJ
Year: 2009
Journal: J Biol Chem
Title: Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system.
Volume: 284
Issue: 5
Pages: 2598-602
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Publication
10707987 | J:60151
First Author: Abeliovich A
Year: 2000
Journal: Neuron
Title: Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system.
Volume: 25
Issue: 1
Pages: 239-52
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Publication
24415155 | J:208051
First Author: Smith BR
Year: 2014
Journal: J Pathol
Title: Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
Volume: 232
Issue: 5
Pages: 509-21
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Publication
29718367 | J:321148
First Author: Scudamore O
Year: 2018
Journal: J Neuropathol Exp Neurol
Title: Increased Oxidative Stress Exacerbates α-Synuclein Aggregation In Vivo.
Volume: 77
Issue: 6
Pages: 443-453
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Publication
21801874 | J:174596
First Author: Stefanova N
Year: 2011
Journal: Am J Pathol
Title: Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.
Volume: 179
Issue: 2
Pages: 954-63
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Publication
28462393 | J:255900
 
First Author: Pathak D
Year: 2017
Journal: eNeuro
Title: Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons.
Volume: 4
Issue: 2
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Publication
19097673 | J:159589
First Author: Al-Wandi A
Year: 2010
Journal: Neurobiol Aging
Title: Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice.
Volume: 31
Issue: 5
Pages: 796-804
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Publication
15784963 | J:121324
First Author: Papachroni K
Year: 2005
Journal: J Mol Neurosci
Title: Peripheral sensory neurons survive in the absence of alpha- and gamma-synucleins.
Volume: 25
Issue: 2
Pages: 157-64
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Publication
27021360 | J:321445
 
First Author: Tarasova TV
Year: 2016
Journal: Dokl Biol Sci
Title: The role of alpha-synuclein in the development of the dopaminergic neurons in the substantia nigra and ventral tegmental area.
Volume: 466
Pages: 5-7
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Publication
20079841 | J:159933
First Author: Cano-Jaimez M
Year: 2010
Journal: Neurobiol Dis
Title: Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein.
Volume: 38
Issue: 1
Pages: 92-103
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Publication
28533388 | J:242277
First Author: Larson ME
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Volume: 114
Issue: 23
Pages: E4648-E4657
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Publication
18333965 | J:132938
First Author: Senior SL
Year: 2008
Journal: Eur J Neurosci
Title: Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein.
Volume: 27
Issue: 4
Pages: 947-57
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Publication
23349488 | J:208568
First Author: Steneberg P
Year: 2013
Journal: Diabetes
Title: The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.
Volume: 62
Issue: 6
Pages: 2004-14
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Publication
29759483 | J:276192
 
First Author: Ugras S
Year: 2018
Journal: EBioMedicine
Title: Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders.
Volume: 31
Pages: 307-319
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Publication
27708076 | J:235638
 
First Author: Mao X
Year: 2016
Journal: Science
Title: Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3.
Volume: 353
Issue: 6307
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Publication
32356558 | J:295385
First Author: Pan PY
Year: 2020
Journal: Hum Mol Genet
Title: Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice.
Volume: 29
Issue: 14
Pages: 2300-2312
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Publication
36230952 | J:335311
 
First Author: Gao F
Year: 2022
Journal: Cells
Title: ATPase Thorase Deficiency Causes α-Synucleinopathy and Parkinson's Disease-like Behavior.
Volume: 11
Issue: 19
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Publication
22905247 | J:189900
First Author: Morrison GJ
Year: 2012
Journal: PLoS One
Title: Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein.
Volume: 7
Issue: 8
Pages: e43288
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Publication
20711648 | J:355870
First Author: Kurz A
Year: 2011
Journal: Cell Mol Life Sci
Title: Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress.
Volume: 68
Issue: 4
Pages: 721-33
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Publication
10964942 | J:64205
First Author: Kahle PJ
Year: 2000
Journal: J Neurosci
Title: Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
Volume: 20
Issue: 17
Pages: 6365-73
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Publication
30046897 | J:312275
First Author: Faustini G
Year: 2018
Journal: Acta Neuropathol
Title: Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease.
Volume: 136
Issue: 4
Pages: 621-639
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Publication
38815862 | J:352324
First Author: Nakamura Y
Year: 2024
Journal: J Biol Chem
Title: Neuronal activity promotes secretory autophagy for the extracellular release of α-synuclein.
Volume: 300
Issue: 7
Pages: 107419
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Publication
36543134 | J:353081
First Author: Ren M
Year: 2022
Journal: Cell Rep
Title: MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
Volume: 41
Issue: 12
Pages: 111852
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Publication
36121476 | J:354599
First Author: Lackie RE
Year: 2022
Journal: Acta Neuropathol
Title: Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo.
Volume: 144
Issue: 5
Pages: 881-910
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Publication
34360942 | J:310415
 
First Author: Di Martino R
Year: 2021
Journal: Int J Mol Sci
Title: Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice.
Volume: 22
Issue: 15
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Publication
23175842 | J:192811
First Author: Winner B
Year: 2012
Journal: J Neurosci
Title: Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus.
Volume: 32
Issue: 47
Pages: 16906-16
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Publication
30877431 | J:308601
First Author: Hu D
Year: 2019
Journal: Acta Neuropathol
Title: Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Volume: 137
Issue: 6
Pages: 939-960
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Publication
38693066 | J:353925
First Author: Li J
Year: 2024
Journal: J Neurochem
Title: The role of age-associated alpha-synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation.
Volume: 168
Issue: 7
Pages: 1215-1236
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Publication
17028574 | J:116060
First Author: Duquet A
Year: 2006
Journal: EMBO Rep
Title: Acetylation is important for MyoD function in adult mice.
Volume: 7
Issue: 11
Pages: 1140-6
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Publication
33428941 | J:302105
   
First Author: Weston LJ
Year: 2021
Journal: J Biol Chem
Title: Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies.
Pages: 100273
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Publication
27358461 | J:234644
First Author: Kim T
Year: 2016
Journal: J Neurosci
Title: Poststroke Induction of α-Synuclein Mediates Ischemic Brain Damage.
Volume: 36
Issue: 26
Pages: 7055-65
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Publication
28257421 | J:243380
First Author: de Oliveira RM
Year: 2017
Journal: PLoS Biol
Title: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.
Volume: 15
Issue: 3
Pages: e2000374
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Publication
25037286 | J:218067
First Author: Oliveras-Salvá M
Year: 2014
Journal: Neurobiol Aging
Title: Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice.
Volume: 35
Issue: 11
Pages: 2625-2636
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Publication
29367610 | J:260213
First Author: Svarcbahs R
Year: 2018
Journal: Sci Rep
Title: Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo.
Volume: 8
Issue: 1
Pages: 1552
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Publication
29166608 | J:254936
First Author: Oh CK
Year: 2017
Journal: Cell Rep
Title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.
Volume: 21
Issue: 8
Pages: 2171-2182
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Publication
23393156 | J:194306
First Author: Schultheis PJ
Year: 2013
Journal: Hum Mol Genet
Title: Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Volume: 22
Issue: 10
Pages: 2067-82
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Publication
25028513 | J:317643
First Author: Suzuki Y
Year: 2014
Journal: J Biol Chem
Title: β-III Tubulin fragments inhibit α-synuclein accumulation in models of multiple system atrophy.
Volume: 289
Issue: 35
Pages: 24374-82
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Publication
24076025 | J:202009
First Author: Roy A
Year: 2013
Journal: FEBS Lett
Title: Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease.
Volume: 587
Issue: 21
Pages: 3567-74
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Publication
24983211 | J:215464
 
First Author: Yin G
Year: 2014
Journal: Neurobiol Dis
Title: α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.
Volume: 70
Pages: 149-61
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Publication
18702517 | J:140580
First Author: Sevlever D
Year: 2008
Journal: Biochemistry
Title: Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species.
Volume: 47
Issue: 36
Pages: 9678-87
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Publication
19012742 | J:143080
First Author: Israeli E
Year: 2009
Journal: J Neurochem
Title: Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein.
Volume: 108
Issue: 2
Pages: 465-74
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Publication
19885730 | J:159509
First Author: Zhong SC
Year: 2010
Journal: Cell Mol Neurobiol
Title: Expression and subcellular location of alpha-synuclein during mouse-embryonic development.
Volume: 30
Issue: 3
Pages: 469-82
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Publication
19553474 | J:164488
First Author: Sousa VL
Year: 2009
Journal: Mol Biol Cell
Title: {alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.
Volume: 20
Issue: 16
Pages: 3725-39
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Publication
24866403 | J:218078
First Author: Du Y
Year: 2014
Journal: Neurobiol Aging
Title: Histone deacetylase 6 regulates cytotoxic α-synuclein accumulation through induction of the heat shock response.
Volume: 35
Issue: 10
Pages: 2316-28
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Publication
26663874 | J:248921
First Author: Chintalapudi SR
Year: 2016
Journal: FEBS J
Title: Multipronged approach to identify and validate a novel upstream regulator of Sncg in mouse retinal ganglion cells.
Volume: 283
Issue: 4
Pages: 678-93
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Publication
22508489 | J:315246
First Author: Spencer B
Year: 2013
Journal: Mol Ther
Title: Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD.
Volume: 21
Issue: 1
Pages: 31-41
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Publication
27881461 | J:329664
First Author: Sambri I
Year: 2017
Journal: EMBO Mol Med
Title: Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases.
Volume: 9
Issue: 1
Pages: 112-132
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Publication
23013868 | J:324569
 
First Author: Sekigawa A
Year: 2012
Journal: Mol Brain
Title: Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.
Volume: 5
Pages: 34
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Publication
9648883 | J:48620
First Author: Hsu LJ
Year: 1998
Journal: J Neurochem
Title: Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development.
Volume: 71
Issue: 1
Pages: 338-44
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Publication
22371502 | J:184367
First Author: Joe MK
Year: 2012
Journal: J Biol Chem
Title: Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex.
Volume: 287
Issue: 16
Pages: 13216-27
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Publication
9750188 | J:50153
First Author: Lavedan C
Year: 1998
Journal: Genome Res
Title: The synuclein family.
Volume: 8
Issue: 9
Pages: 871-80
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Publication
35172141 | J:324659
First Author: Sterling JK
Year: 2022
Journal: Cell Rep
Title: Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
Volume: 38
Issue: 7
Pages: 110358
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Publication
16636270 | J:109461
First Author: Stanic AK
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus.
Volume: 103
Issue: 18
Pages: 7018-23
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Publication
17018883 | J:129277
First Author: Ebadi M
Year: 2006
Journal: Exp Biol Med (Maywood)
Title: Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease.
Volume: 231
Issue: 9
Pages: 1576-83
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Publication
19542206 | J:152425
First Author: Zuo P
Year: 2009
Journal: Toxicol Sci
Title: Potential role of alpha-synuclein and metallothionein in lead-induced inclusion body formation.
Volume: 111
Issue: 1
Pages: 100-8
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Publication
17227870 | J:119515
First Author: Ekstrand MI
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons.
Volume: 104
Issue: 4
Pages: 1325-30
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Publication
28855681 | J:256452
First Author: Aulić S
Year: 2017
Journal: Sci Rep
Title: α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.
Volume: 7
Issue: 1
Pages: 10050
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Publication
27733604 | J:236300
First Author: Ludtmann MH
Year: 2016
Journal: J Neurosci
Title: Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase.
Volume: 36
Issue: 41
Pages: 10510-10521
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Publication
27614017 | J:235050
 
First Author: Connor-Robson N
Year: 2016
Journal: Neurobiol Aging
Title: Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism.
Volume: 46
Pages: 107-12
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Publication
28993630 | J:323747
First Author: Baksi S
Year: 2017
Journal: Sci Rep
Title: α-Synuclein impairs ferritinophagy in the retinal pigment epithelium: Implications for retinal iron dyshomeostasis in Parkinson's disease.
Volume: 7
Issue: 1
Pages: 12843
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Publication
37542299 | J:341051
First Author: Chen X
Year: 2023
Journal: Mol Neurodegener
Title: VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson's disease.
Volume: 18
Issue: 1
Pages: 51
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Publication
33273122 | J:300944
First Author: Somayaji M
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo.
Volume: 117
Issue: 51
Pages: 32701-32710
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Publication
20356833 | J:164560
First Author: Lou H
Year: 2010
Journal: J Biol Chem
Title: Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
Volume: 285
Issue: 23
Pages: 17648-61
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Publication
14585981 | J:86439
First Author: Ninkina N
Year: 2003
Journal: Mol Cell Biol
Title: Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene.
Volume: 23
Issue: 22
Pages: 8233-45
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Publication
33091110 | J:308837
 
First Author: Bassil F
Year: 2021
Journal: J Exp Med
Title: α-Synuclein modulates tau spreading in mouse brains.
Volume: 218
Issue: 1
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Publication
15147505 | J:92213
First Author: Robertson DC
Year: 2004
Journal: J Neurochem
Title: Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice.
Volume: 89
Issue: 5
Pages: 1126-36
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Publication
25917213 | J:309832
First Author: Lee SK
Year: 2015
Journal: Cerebellum
Title: α-Synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells.
Volume: 14
Issue: 5
Pages: 516-27
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Publication
31899072 | J:291156
First Author: Henderson MX
Year: 2020
Journal: Neuron
Title: Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult.
Volume: 105
Issue: 5
Pages: 822-836.e7
•
•
•
•
•
Publication
22355774 | J:207278
 
First Author: Shimshek DR
Year: 2012
Journal: Sci Rep
Title: Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1.
Volume: 2
Pages: 262
•
•
•
•
•
Publication
26451483 | J:226090
First Author: Ejlerskov P
Year: 2015
Journal: Cell
Title: Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia.
Volume: 163
Issue: 2
Pages: 324-39
•
•
•
•
•
Publication
15465911 | J:93544
First Author: Chandra S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions.
Volume: 101
Issue: 41
Pages: 14966-71
•
•
•
•
•
Publication
27348587 | J:232550
First Author: Brahmachari S
Year: 2016
Journal: J Clin Invest
Title: Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration.
Volume: 126
Issue: 8
Pages: 2970-88
•
•
•
•
•
Publication
28039592 | J:323046
First Author: Pavlin T
Year: 2017
Journal: Neurochem Res
Title: Loss or Mislocalization of Aquaporin-4 Affects Diffusion Properties and Intermediary Metabolism in Gray Matter of Mice.
Volume: 42
Issue: 1
Pages: 77-91
•
•
•
•
•
Publication
20056137 | J:159729
First Author: Kurz A
Year: 2010
Journal: Neuroscience
Title: Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization.
Volume: 166
Issue: 3
Pages: 785-95
•
•
•
•
•
Publication
23209687 | J:195450
First Author: Schell H
Year: 2012
Journal: PLoS One
Title: Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned α-synuclein transgenic mice.
Volume: 7
Issue: 11
Pages: e50245
•
•
•
•
•
Publication
19680561 | J:244610
First Author: Fournier M
Year: 2009
Journal: PLoS One
Title: Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
Volume: 4
Issue: 8
Pages: e6629
•
•
•
•
•
Publication
24619358 | J:210987
First Author: Diepenbroek M
Year: 2014
Journal: Hum Mol Genet
Title: Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Volume: 23
Issue: 15
Pages: 3975-89
•
•
•
•
•
Publication
26099047 | J:224864
First Author: Bachhuber T
Year: 2015
Journal: Nat Med
Title: Inhibition of amyloid-β plaque formation by α-synuclein.
Volume: 21
Issue: 7
Pages: 802-7
•
•
•
•
•
Publication
34508096 | J:314207
First Author: Dutta D
Year: 2021
Journal: Nat Commun
Title: Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo.
Volume: 12
Issue: 1
Pages: 5382
•
•
•
•
•
Publication
28288128 | J:244405
First Author: Logan T
Year: 2017
Journal: Nat Neurosci
Title: α-Synuclein promotes dilation of the exocytotic fusion pore.
Volume: 20
Issue: 5
Pages: 681-689
•
•
•
•
•
Publication
20974939 | J:167549
First Author: Greten-Harrison B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction.
Volume: 107
Issue: 45
Pages: 19573-8
•
•
•
•
•
Publication
35417693 | J:325104
First Author: Carnazza KE
Year: 2022
Journal: Cell Rep
Title: Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins.
Volume: 39
Issue: 2
Pages: 110675
•
•
•
•
•
Publication
37516240 | J:340456
First Author: Vargas KJ
Year: 2023
Journal: J Biol Chem
Title: α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices.
Volume: 299
Issue: 9
Pages: 105091
•
•
•
•
•
Publication
16597723 | J:107254
First Author: von Coelln R
Year: 2006
Journal: J Neurosci
Title: Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
Volume: 26
Issue: 14
Pages: 3685-96
•
•
•
•
•
Publication
23129765 | J:193755
First Author: Ninkina N
Year: 2012
Journal: J Biol Chem
Title: Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses.
Volume: 287
Issue: 53
Pages: 44471-7
•
•
•
•
•
Publication
21846727 | J:177590
First Author: Emmer KL
Year: 2011
Journal: J Biol Chem
Title: E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment.
Volume: 286
Issue: 40
Pages: 35104-18
•
•
•
•
•
Publication
29547959 | J:261581
First Author: Papadopoulos VE
Year: 2018
Journal: Hum Mol Genet
Title: Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.
Volume: 27
Issue: 10
Pages: 1696-1710
•
•
•
•
•
Publication
34321069 | J:328429
First Author: Ha TY
Year: 2021
Journal: Mol Brain
Title: Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons.
Volume: 14
Issue: 1
Pages: 122
•
•
•
•
•
Publication
25009269 | J:215304
First Author: Vargas KJ
Year: 2014
Journal: J Neurosci
Title: Synucleins regulate the kinetics of synaptic vesicle endocytosis.
Volume: 34
Issue: 28
Pages: 9364-76
•
•
•
•
•
Publication
11572944 | J:72239
First Author: Masliah E
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.
Volume: 98
Issue: 21
Pages: 12245-50
•
•
•
•
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