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Search results 601 to 700 out of 735 for Tardbp

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Type Details Score
Allele
Tg(Thy1-TARDBP)6Singh | MGI:4438491
Name: transgene insertion 6, Samir Kumar-Singh
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-TARDBP)4Jlel | MGI:4839645
Name: transgene insertion 4, Jeffrey L Elliott
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(tetO-TARDBP)12Vle | MGI:5000260
Name: transgene insertion 12, Virginia M Y Lee
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(tetO-TARDBP*)4Vle | MGI:5000261
Name: transgene insertion 4, Virginia M Y Lee
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Allele
Tg(Prnp-TARDBP*Q331K)103Dwc | MGI:5463119
Name: transgene insertion 103, Don W Cleveland
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu | MGI:5559582
Name: transgene insertion 6, Zuoshang Xu
Allele Type: Transgenic
Attribute String: Knockdown, Reporter
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Allele
Tg(tetO-TARDBP*A315T)13Lmit | MGI:5922010
Name: transgene insertion 13, Lars M Ittner
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Tardbp<tm3.1Ckjs> | MGI:6404633
Name: TAR DNA binding protein; targeted mutation 3.1, C K James Shen
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Tardbp<tm1.1Sobue> | MGI:7311560
Name: TAR DNA binding protein; targeted mutation 1.1, Gen Sobue
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(Thy1-TARDBP*)BOddo | MGI:5310969
Name: transgene insertion B, Salvatore Oddo
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TARDBP*A315T)#Jpj | MGI:5476824
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TARDBP)#Jpj | MGI:5476821
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tardbp<em2Smoc> | MGI:7292688
Name: TAR DNA binding protein; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Tardbp<tm1(TARDBP)Smoc> | MGI:7786941
Name: TAR DNA binding protein; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(TARDBP*G348C)#Jpj | MGI:5476825
Name: transgene insertion, Jean-Pierre Julien
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP)6Singh/Tg(Thy1-TARDBP)6Singh
Background: involves: C57BL/6 * C57BL/6J * SJL
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Transgene
MGI:4839652 | Tg(Prnp-TARDBP*A315T)23Jlel
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4839651 | Tg(Prnp-TARDBP)4Jlel
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5000263 | Tg(tetO-TARDBP)12Vle
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5000262 | Tg(tetO-TARDBP*)4Vle
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5463118 | Tg(Prnp-TARDBP*Q331K)103Dwc
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5559587 | Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5922012 | Tg(tetO-TARDBP*A315T)13Lmit
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)4Jlel/?
Background: involves: C57BL/6 * CD-1 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO-TARDBP)12Vle/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO-TARDBP*)4Vle/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mnx1/Mnx1<+> Tardbp/Tardbp
Background: involves: 129S1/Sv * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-dsRed2/RNAi:Tardbp)6Zxu/?
Background: involves: C57BL/6 * C57BL/6J * FVB/NJ * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(NEFH-tTA)8Vle/? Tg(tetO-TARDBP*)4Vle/?
Background: involves: C3H/HeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)96Dwc/? Tg(Prnp-TARDBP*Q331K)31Dwc/?
Background: involves: C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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DO Term
DOID:0060201 | amyotrophic lateral sclerosis type 10
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Genotype
Genotype
Symbol: Tg(tetO-TARDBP*A315T)13Lmit/? Tg(Thy1-tTA)6Lmit/?
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP*Q331K)103Dwc/?
Background: B6.Cg-Tg(Prnp-TARDBP*Q331K)103Dwc/J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: involves: C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp Tg(SLC18A3-cre)Misa/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP*A315T)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(TARDBP*G348C)#Jpj/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/Tg(Thy1-TARDBP*)BOddo
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6771207 | C57BL/6JSmoc-Tardbp<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Prnp-TARDBP)1Koya | MGI:7382830
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7788788 | C57BL/6JSmoc-Tardbp<tm1(TARDBP)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
22029574 | J:179348
 
First Author: Xu YF
Year: 2011
Journal: Mol Neurodegener
Title: Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice.
Volume: 6
Pages: 73
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Allele
Tardbp<tm1(TARDBP*G348C/Venus)Okn> | MGI:5819107
Name: TAR DNA binding protein; targeted mutation 1, Hideyuki Okano
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tardbp<tm2(TARDBP*A382T/Venus)Okn> | MGI:5819108
Name: TAR DNA binding protein; targeted mutation 2, Hideyuki Okano
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tardbp<em1Smoc> | MGI:7292687
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7386798 | B6.Cg-Tg(Prnp-TARDBP)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
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Allele
Tg(Prnp-TARDBP*R208)1Koya | MGI:7382863
Name: transgene insertion 1, Koji Yamanaka
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tardbp<tm1.1Pcw> | MGI:4834273
Name: TAR DNA binding protein; targeted mutation 1.1, Philip C Wong
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Tg(Prnp-TARDBP*M337V)4Ptrc | MGI:5301818
Name: transgene insertion 4, Leonard Petrucelli
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Prnp-TARDBP*A315T)95Balo | MGI:4358722
Name: transgene insertion 95, Robert Baloh
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(Thy1-TARDBP)4Singh | MGI:4438490
Name: transgene insertion 4, Samir Kumar-Singh
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-TARDBP)3cPtrc | MGI:5002476
Name: transgene insertion 3c, Leonard Petrucelli
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tardbp<em1Rhbr> | MGI:6157626
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Robert Brown Jr
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Publication
20133711 | J:157550
First Author: Wils H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Volume: 107
Issue: 8
Pages: 3858-63
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Publication
29787578 | J:263558
First Author: Scherz B
Year: 2018
Journal: PLoS One
Title: mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms.
Volume: 13
Issue: 5
Pages: e0197674
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Strain
MGI:5308204 | B6(SJL)-Tardbp<tm1.1Pcw>/J
Attribute String: mutant strain, targeted mutation
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Strain
MGI:5301828 | C57BL/6-Tg(Prnp-TARDBP*M337V)4Ptrc/J
Attribute String: coisogenic, transgenic, mutant strain
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Publication
28335005 | J:250252
First Author: Gu J
Year: 2017
Journal: Nucleic Acids Res
Title: TDP-43 suppresses tau expression via promoting its mRNA instability.
Volume: 45
Issue: 10
Pages: 6177-6193
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Allele
Tg(Krt8-TARDBP)#Say | MGI:6275553
Name: transgene insertion, Satoshi Yamashita
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7386799 | B6.Cg-Tg(Prnp-TARDBP*R208)1Koya/Koya
Attribute String: congenic, mutant strain, transgenic
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Allele
Tardbp<tm1(TARDBP)Cya> | MGI:7657331
Name: TAR DNA binding protein; targeted mutation 1, Cyagen Biosciences
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
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Allele
Gt(ROSA)26Sor<tm1(CAG-TARDBP*M337V)Koya> | MGI:7790992
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Koji Yamanaka
Allele Type: Targeted
Attribute String: Conditional ready, Epitope tag, Humanized sequence
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Allele
Gt(ROSA)26Sor<tm2(TARDBP)Tlbt> | MGI:7859507
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Kevin Talbot
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp
Background: involves: C57BL/6J * SJL
Zygosity: hm
Has Mutant Allele: true
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Transgene
MGI:4358721 | Tg(Prnp-TARDBP*A315T)95Balo
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4438486 | Tg(Thy1-TARDBP)4Singh
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:4438487 | Tg(Thy1-TARDBP)6Singh
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5002478 | Tg(Prnp-TARDBP)3cPtrc
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5310798 | Tg(Thy1-TARDBP*)BOddo
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5476814 | Tg(TARDBP)#Jpj
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5476817 | Tg(TARDBP*A315T)#Jpj
Type: transgene
Organism: mouse, laboratory
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Transgene
MGI:5476818 | Tg(TARDBP*G348C)#Jpj
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP*A315T)95Balo/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP)4Singh/Tg(Thy1-TARDBP)4Singh
Background: involves: C57BL/6J * SJL/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP)4Singh/?
Background: involves: C57BL/6J * SJL/J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-TARDBP)3cPtrc/Tg(Prnp-TARDBP)3cPtrc
Background: C57BL/6-Tg(Prnp-TARDBP)3cPtrc
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp
Background: C57BL/6J-Tardbp
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5319367 | B6SJL-Tg(Prnp-TARDBP*A315T)23Jlel/J
Attribute String: mutant stock, transgenic
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Strain
MGI:4943773 | STOCK Tg(Prnp-TARDBP*A315T)23Jlel/J
Attribute String: mutant stock, transgenic
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Strain
MGI:5311109 | C57BL/6-Tg(Thy1-TARDBP*)BOddo
Attribute String: transgenic, mutant strain, coisogenic
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Publication
22067910 | J:180165
First Author: Caccamo A
Year: 2012
Journal: Am J Pathol
Title: Cognitive decline typical of frontotemporal lobar degeneration in transgenic mice expressing the 25-kDa C-terminal fragment of TDP-43.
Volume: 180
Issue: 1
Pages: 293-302
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Publication
26002100 | J:223932
First Author: Caccamo A
Year: 2015
Journal: Hum Mol Genet
Title: Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43.
Volume: 24
Issue: 16
Pages: 4625-35
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Publication
31406156 | J:284842
First Author: Yamashita S
Year: 2019
Journal: Sci Rep
Title: CYLD dysregulation in pathogenesis of sporadic inclusion body myositis.
Volume: 9
Issue: 1
Pages: 11606
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Strain
MGI:6405397 | B6(C3)-Tardbp<tm1.1Neas>
Attribute String: mutant strain, targeted mutation
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Strain
MGI:6405400 | B6(C3)-Tardbp<tm2.1Neas>
Attribute String: targeted mutation, mutant strain
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Allele
Tardbp<em1Koya> | MGI:6405404
Name: TAR DNA binding protein; endonuclease-mediated mutation 1, Koji Yamanaka
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Allele
Tg(Prnp-Tardbp,-EGFP)19Zxu | MGI:6469530
Name: transgene insertion 19, Zuoshang Xu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Strain
MGI:6469538 | FVB/NJ-Tg(Prnp-Tardbp,-EGFP)19Zxu/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
35113871 | J:319624
First Author: Yang C
Year: 2022
Journal: PLoS One
Title: Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.
Volume: 17
Issue: 2
Pages: e0255710
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Publication
29097807 | J:265116
First Author: Tsuiji H
Year: 2017
Journal: Sci Rep
Title: TDP-43 accelerates age-dependent degeneration of interneurons.
Volume: 7
Issue: 1
Pages: 14972
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Allele
Tardbp<tm1.1(TARDBP)Mdk> | MGI:7576944
Name: TAR DNA binding protein; targeted mutation 1.1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Strain
MGI:7657605 | C57BL/6J-Tardbp<tm1(TARDBP)Cya>/Cya
Attribute String: coisogenic, targeted mutation, mutant strain
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Strain
MGI:7859508 | B6.Cg-Gt(ROSA)26Sor<tm2(TARDBP)Tlbt>/H
Attribute String: mutant strain, targeted mutation, congenic
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Genotype
Genotype
Symbol: Tg(Thy1-TARDBP*)BOddo/?
Background: C57BL/6-Tg(Thy1-TARDBP*)BOddo
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: B6(C3)-Tardbp
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp<+>
Background: B6(C3)-Tardbp
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tardbp/Tardbp Tg(Zp3-cre)93Knw/?
Background: involves: C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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