Type |
Details |
Score |
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
552
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
452
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Allele |
Name: |
T-box 4; targeted mutation 1.1, David M Kingsley |
Allele Type: |
Targeted |
Attribute String: |
Modified regulatory region |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1201355 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-11-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1678119 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5912539 |
Age: |
embryonic day 11.5 |
Image: |
2Bd' |
Note: |
Expression broadly overlaps with Tbx4 throughout the proximal limb mesenchyme. |
Specimen Label: |
2Bd' |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1201355 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-11-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1678117 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5912539 |
Age: |
embryonic day 10.5 |
Image: |
2Ba' |
Note: |
Expression broadly overlaps with Tbx4 throughout the proximal limb mesenchyme. |
Specimen Label: |
2Ba' |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1201355 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-11-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Widespread |
Stage: |
TS17 |
Assay Id: |
MGI:5912539 |
Age: |
embryonic day 10.5 |
Image: |
2Ba |
Note: |
Expression overlaps with the broader of Tbx4 expression domain. |
Specimen Label: |
2Ba |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1201355 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-11-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640619 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5912539 |
Age: |
embryonic day 11.5 |
Image: |
2Bd |
Note: |
Expressed at the proximal part. Expression patterns of Shox2 and Tbx4 are mutually exclusive. |
Specimen Label: |
2Bd |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1333201 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640817 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:3846941 |
Age: |
embryonic day 10.5 |
Image: |
1L |
Note: |
Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained. |
Specimen Label: |
1L |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1333201 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-06-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1677917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:3846941 |
Age: |
embryonic day 10.5 |
Image: |
1L |
Note: |
Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained. |
Specimen Label: |
1L |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1201355 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-11-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1741220 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:5912539 |
Age: |
embryonic day 12.5 |
Image: |
2Bg |
Note: |
Expressed at the proximal part. Expression patterns of Shox2 and Tbx4 are mutually exclusive. |
Specimen Label: |
2Bg |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Wei Shi |
Allele Type: |
Transgenic |
Attribute String: |
Reporter, Transactivator |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Miao Q |
Year: |
2021 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Q |
Year: |
2023 |
Journal: |
J Pathol |
Title: |
Myocd regulates airway smooth muscle cell remodeling in response to chronic asthmatic injury. |
Volume: |
259 |
Issue: |
3 |
Pages: |
331-341 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernau K |
Year: |
2021 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Expression of serum response factor in the lung mesenchyme is essential for development of pulmonary fibrosis. |
Volume: |
321 |
Issue: |
1 |
Pages: |
L174-L188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Young RE |
Year: |
2020 |
Journal: |
Dev Cell |
Title: |
Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching. |
Volume: |
53 |
Issue: |
1 |
Pages: |
73-85.e5 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
He H |
Year: |
2021 |
Journal: |
Cell Death Dis |
Title: |
PRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis. |
Volume: |
12 |
Issue: |
9 |
Pages: |
841 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stokes G |
Year: |
2024 |
Journal: |
Sci Transl Med |
Title: |
Rescuing lung development through embryonic inhibition of histone acetylation. |
Volume: |
16 |
Issue: |
732 |
Pages: |
eadc8930 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishimoto S |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation. |
Volume: |
12 |
Issue: |
5 |
Pages: |
879-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minguillon C |
Year: |
2012 |
Journal: |
Development |
Title: |
Hox genes regulate the onset of Tbx5 expression in the forelimb. |
Volume: |
139 |
Issue: |
17 |
Pages: |
3180-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oruqaj G |
Year: |
2023 |
Journal: |
Am J Pathol |
Title: |
Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models. |
Volume: |
193 |
Issue: |
3 |
Pages: |
259-274 |
|
•
•
•
•
•
|
Publication |
First Author: |
Noe N |
Year: |
2019 |
Journal: |
Lab Invest |
Title: |
Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Goodwin K |
Year: |
2023 |
Journal: |
Dev Cell |
Title: |
Plasticity in airway smooth muscle differentiation during mouse lung development. |
Volume: |
58 |
Issue: |
5 |
Pages: |
338-347.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
del Moral PM |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung. |
Volume: |
293 |
Issue: |
1 |
Pages: |
77-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang JS |
Year: |
2018 |
Journal: |
Dev Biol |
Title: |
PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets. |
Volume: |
434 |
Issue: |
1 |
Pages: |
186-195 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2015 |
Journal: |
J Pathol |
Title: |
A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. |
Volume: |
236 |
Issue: |
3 |
Pages: |
384-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teramoto M |
Year: |
2020 |
Journal: |
Biol Open |
Title: |
The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components. |
Volume: |
9 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jain D |
Year: |
2018 |
Journal: |
Development |
Title: |
Regulatory integration of Hox factor activity with T-box factors in limb development. |
Volume: |
145 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2015 |
Journal: |
BMC Biol |
Title: |
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. |
Volume: |
13 |
|
Pages: |
42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li R |
Year: |
2020 |
Journal: |
J Clin Invest |
Title: |
Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface. |
Volume: |
130 |
Issue: |
6 |
Pages: |
2859-2871 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goodwin K |
Year: |
2022 |
Journal: |
iScience |
Title: |
Patterning the embryonic pulmonary mesenchyme. |
Volume: |
25 |
Issue: |
3 |
Pages: |
103838 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paramore SV |
Year: |
2024 |
Journal: |
Dev Cell |
Title: |
Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. |
Volume: |
59 |
Issue: |
10 |
Pages: |
1302-1316.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paramore SV |
Year: |
2024 |
Journal: |
Development |
Title: |
Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex. |
Volume: |
151 |
Issue: |
16 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1617-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
1999 |
Journal: |
Methods Enzymol |
Title: |
High-efficiency full-length cDNA cloning. |
Volume: |
303 |
|
Pages: |
19-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata K |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1757-71 |
|
•
•
•
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Publication |
First Author: |
Katayama S |
Year: |
2005 |
Journal: |
Science |
Title: |
Antisense transcription in the mammalian transcriptome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1564-6 |
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Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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