| Type |
Details |
Score |
| Publication |
| First Author: |
Xiao Q |
| Year: |
2014 |
| Journal: |
J Neurosci |
| Title: |
Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis. |
| Volume: |
34 |
| Issue: |
29 |
| Pages: |
9607-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim SH |
| Year: |
2017 |
| Journal: |
Autophagy |
| Title: |
Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. |
| Volume: |
13 |
| Issue: |
10 |
| Pages: |
1767-1781 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chua JP |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. |
| Volume: |
23 |
| Issue: |
5 |
| Pages: |
1376-86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu M |
| Year: |
2017 |
| Journal: |
Am J Physiol Lung Cell Mol Physiol |
| Title: |
Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia. |
| Volume: |
313 |
| Issue: |
1 |
| Pages: |
L138-L153 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raha S |
| Year: |
2021 |
| Journal: |
Sci Signal |
| Title: |
Activation of PPARα enhances astroglial uptake and degradation of β-amyloid. |
| Volume: |
14 |
| Issue: |
706 |
| Pages: |
eabg4747 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin W |
| Year: |
2023 |
| Journal: |
J Neuroinflammation |
| Title: |
TNEA therapy promotes the autophagic degradation of NLRP3 inflammasome in a transgenic mouse model of Alzheimer's disease via TFEB/TFE3 activation. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKee CA |
| Year: |
2023 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes. |
| Volume: |
120 |
| Issue: |
20 |
| Pages: |
e2220551120 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baron O |
| Year: |
2017 |
| Journal: |
Curr Biol |
| Title: |
Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration. |
| Volume: |
27 |
| Issue: |
23 |
| Pages: |
3626-3642.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paquette M |
| Year: |
2021 |
| Journal: |
Sci Rep |
| Title: |
Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
21268 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen Z |
| Year: |
2018 |
| Journal: |
Theranostics |
| Title: |
Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling. |
| Volume: |
8 |
| Issue: |
3 |
| Pages: |
627-643 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shyam R |
| Year: |
2021 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. |
| Volume: |
62 |
| Issue: |
12 |
| Pages: |
15 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stagi M |
| Year: |
2014 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B. |
| Volume: |
61 |
|
| Pages: |
226-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Theeuwes WF |
| Year: |
2020 |
| Journal: |
Biochim Biophys Acta Mol Cell Res |
| Title: |
Regulation of PGC-1α expression by a GSK-3β-TFEB signaling axis in skeletal muscle. |
| Volume: |
1867 |
| Issue: |
2 |
| Pages: |
118610 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim SW |
| Year: |
2019 |
| Journal: |
FASEB J |
| Title: |
Effect of Klotho on autophagy clearance in tacrolimus-induced renal injury. |
| Volume: |
33 |
| Issue: |
2 |
| Pages: |
2694-2706 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim S |
| Year: |
2020 |
| Journal: |
Autophagy |
| Title: |
ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota. |
|
|
| Pages: |
1-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cinque L |
| Year: |
2020 |
| Journal: |
EMBO J |
| Title: |
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B. |
| Volume: |
39 |
| Issue: |
17 |
| Pages: |
e105696 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan Q |
| Year: |
2017 |
| Journal: |
Mol Pharmacol |
| Title: |
Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death. |
| Volume: |
92 |
| Issue: |
6 |
| Pages: |
640-652 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ni H |
| Year: |
2020 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Nicotine Modulates CTSS (Cathepsin S) Synthesis and Secretion Through Regulating the Autophagy-Lysosomal Machinery in Atherosclerosis. |
| Volume: |
40 |
| Issue: |
9 |
| Pages: |
2054-2069 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2018 |
| Journal: |
J Pathol |
| Title: |
Advanced glycation end-products suppress autophagic flux in podocytes by activating mammalian target of rapamycin and inhibiting nuclear translocation of transcription factor EB. |
| Volume: |
245 |
| Issue: |
2 |
| Pages: |
235-248 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akwa Y |
| Year: |
2023 |
| Journal: |
Autophagy |
| Title: |
Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. |
| Volume: |
19 |
| Issue: |
2 |
| Pages: |
660-677 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reed CB |
| Year: |
2020 |
| Journal: |
J Neurosci |
| Title: |
Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury. |
| Volume: |
40 |
| Issue: |
32 |
| Pages: |
6165-6176 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim HK |
| Year: |
2021 |
| Journal: |
Autophagy |
| Title: |
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium. |
| Volume: |
17 |
| Issue: |
3 |
| Pages: |
761-778 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakashima A |
| Year: |
2020 |
| Journal: |
Autophagy |
| Title: |
Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia. |
| Volume: |
16 |
| Issue: |
10 |
| Pages: |
1771-1785 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanaka Y |
| Year: |
2013 |
| Journal: |
Neuroscience |
| Title: |
Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice. |
| Volume: |
250 |
|
| Pages: |
8-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gu S |
| Year: |
2020 |
| Journal: |
Circ Res |
| Title: |
Downregulation of LAPTM4B Contributes to the Impairment of the Autophagic Flux via Unopposed Activation of mTORC1 Signaling During Myocardial Ischemia/Reperfusion Injury. |
| Volume: |
127 |
| Issue: |
7 |
| Pages: |
e148-e165 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang YT |
| Year: |
2019 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration. |
| Volume: |
317 |
| Issue: |
5 |
| Pages: |
C1034-C1047 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Albanese F |
| Year: |
2021 |
| Journal: |
Neurobiol Dis |
| Title: |
Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. |
| Volume: |
159 |
|
| Pages: |
105487 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Klein M |
| Year: |
2022 |
| Journal: |
Autophagy |
| Title: |
Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system. |
| Volume: |
18 |
| Issue: |
9 |
| Pages: |
2068-2085 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang SM |
| Year: |
2023 |
| Journal: |
Autophagy |
| Title: |
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
126-151 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
526
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
317
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
419
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
357
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
520
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
501
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
2024 |
| Journal: |
Alzheimers Res Ther |
| Title: |
Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer's disease. |
| Volume: |
16 |
| Issue: |
1 |
| Pages: |
121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye J |
| Year: |
2025 |
| Journal: |
Mol Neurodegener |
| Title: |
Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pan B |
| Year: |
2019 |
| Journal: |
Front Physiol |
| Title: |
Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress. |
| Volume: |
10 |
|
| Pages: |
758 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang L |
| Year: |
2022 |
| Journal: |
Autophagy |
| Title: |
Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy. |
| Volume: |
18 |
| Issue: |
4 |
| Pages: |
765-782 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
348
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
361
 |
| Fragment?: |
true |
|
•
•
•
•
•
|