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Search results 601 to 700 out of 753 for Traf2

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Type Details Score
Publication
10192335 | J:54099
First Author: Kurts C
Year: 1999
Journal: Nature
Title: Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells.
Volume: 398
Issue: 6725
Pages: 341-4
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Publication
10727988 | -
First Author: Dürkop H
Year: 2000
Journal: J Pathol
Title: Expression of the CD30 antigen in non-lymphoid tissues and cells.
Volume: 190
Issue: 5
Pages: 613-8
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Publication
12714494 | -
First Author: Francisco JA
Year: 2003
Journal: Blood
Title: cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity.
Volume: 102
Issue: 4
Pages: 1458-65
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Publication
19760068 | -
 
First Author: Gough MJ
Year: 2009
Journal: Adv Exp Med Biol
Title: OX40 (CD134) and OX40L.
Volume: 647
Pages: 94-107
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Publication
15173831 | -
First Author: Sugamura K
Year: 2004
Journal: Nat Rev Immunol
Title: Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.
Volume: 4
Issue: 6
Pages: 420-31
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Publication
11567634 | J:71803
First Author: Rogers PR
Year: 2001
Journal: Immunity
Title: OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells.
Volume: 15
Issue: 3
Pages: 445-55
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Publication
27519474 | -
First Author: Chua KH
Year: 2016
Journal: Int J Immunogenet
Title: TNFSF4 polymorphisms are associated with systemic lupus erythematosus in the Malaysian population.
Volume: 43
Issue: 5
Pages: 303-9
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Protein Domain
IPR033995 | TNFRSF1A_N_teleost
Type: Domain
Description: This subfamily of tumor necrosis factor receptor 1A (TNFRSF1, also known as type I TNFR, TNFR1, DR1, TNFRSF1A, CD120a, p55) is found in teleosts. It binds TNF-alpha, through the death domain (DD), and activates NF-kappaB, mediates apoptosis and activates signaling pathways controlling inflammatory, immune, and stress responses. It mediates signal transduction by interacting with antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRAF2 and TRADD that play regulatory roles [, ].Knockout studies in zebrafish embryos have shown that a signaling balance between TNFRSF1A and TNFRSF1B is required for endothelial cell integrity. TNFRSF1A signals apoptosis through caspase-8, whereas TNFRSF1B signals survival via NF-kappaB in endothelial cells. Thus, this apoptotic pathway seems to be evolutionarily conserved, as TNFalpha promotes apoptosis of human endothelial cells and triggers caspase-2 and P53 activation in these cells via TNFRSF1A [].This entry represents the N-terminal domain of TNFR1A from teleosts. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein Domain
IPR033993 | TNFRSF1A_N
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A, also known as type I TNFR, TNFR1, DR1, CD120a, p55) binds TNF-alpha, through the death domain (DD), and activates NF-kappaB, mediates apoptosis and activates signaling pathways controlling inflammatory, immune, and stress responses. It mediates signal transduction by interacting with antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRAF2 and TRADD that play regulatory roles [, ].The human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS), or periodic fever syndrome, is associated with germline mutations of the extracellular domains of this receptor, possibly due to impaired receptor clearance []. TNFRSF1A polymorphisms rs1800693 and rs4149584 are associated with elevated risk of multiple sclerosis []. Serum levels of TNFRSF1A are elevated in schizophrenia and bipolar disorder, and high levels are also associated with cognitive impairment and dementia [, ]. Patients with idiopathic recurrent acute pericarditis (IRAP), presumed to be an autoimmune process, have also been shown to carry rare mutations (R104Q and D12E) in the TNFRSF1A gene [].This entry represents the N-terminal domain of TNFR1A. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein Domain
IPR034000 | TNFRSF7_N
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), also known as CD27, T14, S152, Tp55, S152 or LPFS2, has a key role in the generation of immunological memory via effects on T-cell expansion and survival, and B cell development [, ]. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK, and mediates the signaling process through adaptor proteins TRAF2 and TRAF5. CD27-binding protein (SIVA), a pro-apoptotic protein, can bind to CD27 and may play an important role in the apoptosis induced by this receptor []. The potential role of the CD27/CD70 pathway in the course of inflammatory diseases, such as arthritis, and inflammatory bowel disease, suggests that CD70 may be a target for immune intervention. The expression of CD27 and CD44 molecules correlates with the differentiation stage of B cell precursors and has been shown to have a biological significance in acute lymphoblastic leukemia [].This entry represents the N-terminal domain of TNFRSF7. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein Domain
IPR034002 | TNFRSF8_N
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 8 (TNFRSF8), also known as CD30, Ki-1 or D1S166E, is expressed by activated T and B cells. It transduces signals that lead to the activation of NF-kappaB, mediated by the adaptor proteins TRAF2 and TRAF5 []. This receptor has been shown to limit the proliferative potential of auto-reactive CD8 effector T cells and protect the body against autoimmunity []. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. CD30 is expressed in malignant Hodgkin and Reed-Sternberg cells on the surface of extracellular vesicles, facilitating CD30-CD30L interaction between cell types []. This receptor is also associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma, but not in seminoma, making it a useful marker in distinguishing between these germ cell tumors [, ]. Since CD30 has restricted expression in normal tissues, it is an optimal target for selectively eliminating CD30-expressing neoplastic cells by specific toxin-conjugated monoclonal antibodies (mAbs) [, ].This entry represents the N-terminal domain of TNFRSF8. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein Domain
IPR034022 | TNFRSF4_N
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as OX40, ACT35, CD134, IMD16 or TXGP1L, activates NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5 []. It also promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis []. It is primarily expressed on activated CD4+ and CD8+ T cells, where it is transiently expressed and upregulated on the most recently antigen-activated T cells within inflammatory lesions. This makes it an attractive target to modulate immune responses, i.e. TNFRSF4 (OX40) blocking agents to inhibit adverse inflammation or agonists to enhance immune responses [, ]. An artificially created biologic fusion protein, OX40-immunoglobulin (OX40-Ig), prevents OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Some single nucleotide polymorphisms (SNPs) of its natural ligand OX40 ligand (OX40L, CD252), which is also found on activated T cells, have been associated with systemic lupus erythematosus [].This entry represents the N-terminal domain of TNFRSF4. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number of modules can vary in number and type in different members of the family [, , ].
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Publication
15833743 | J:204505
First Author: Das S
Year: 2005
Journal: J Biol Chem
Title: Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner.
Volume: 280
Issue: 25
Pages: 23748-57
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Publication
11882293 | J:75381
First Author: Yan M
Year: 2002
Journal: Curr Biol
Title: Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice.
Volume: 12
Issue: 5
Pages: 409-13
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Publication
11278723 | J:186075
First Author: Yoneda T
Year: 2001
Journal: J Biol Chem
Title: Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
Volume: 276
Issue: 17
Pages: 13935-40
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Publication
10801798 | J:63297
First Author: Nakano K
Year: 2000
Journal: J Biol Chem
Title: NESK, a member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and is expressed during the late stages of embryogenesis.
Volume: 275
Issue: 27
Pages: 20533-9
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Publication
8663299 | J:33749
First Author: Nakano H
Year: 1996
Journal: J Biol Chem
Title: TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.
Volume: 271
Issue: 25
Pages: 14661-4
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Publication
10581243 | J:66310
First Author: Pomerantz JL
Year: 1999
Journal: EMBO J
Title: NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.
Volume: 18
Issue: 23
Pages: 6694-704
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Publication
10990461 | J:91653
First Author: Bonnard M
Year: 2000
Journal: EMBO J
Title: Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription.
Volume: 19
Issue: 18
Pages: 4976-85
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Publication
15175328 | J:91832
First Author: Lee TH
Year: 2004
Journal: J Biol Chem
Title: The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.
Volume: 279
Issue: 32
Pages: 33185-91
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Publication
10753917 | J:61738
First Author: Yoneda T
Year: 2000
Journal: J Biol Chem
Title: Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.
Volume: 275
Issue: 15
Pages: 11114-20
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Publication
11086053 | J:118025
First Author: Cannons JL
Year: 2000
Journal: J Immunol
Title: Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response.
Volume: 165
Issue: 11
Pages: 6193-204
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Publication
19113817 | J:355604
First Author: Li Q
Year: 2009
Journal: Antioxid Redox Signal
Title: Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha.
Volume: 11
Issue: 6
Pages: 1249-63
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Publication
19074147 | J:147593
First Author: Li H
Year: 2009
Journal: J Biol Chem
Title: Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-kappaB-inducing kinase and p38 mitogen-activated protein kinase: a potential role of MMP-9 in myopathy.
Volume: 284
Issue: 7
Pages: 4439-50
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Publication
23990781 | J:214498
First Author: Ogolla PS
Year: 2013
Journal: PLoS Pathog
Title: The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.
Volume: 9
Issue: 8
Pages: e1003557
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Publication
32275117 | J:316350
First Author: Shen Y
Year: 2020
Journal: FASEB J
Title: TRAF3 promotes ROS production and pyroptosis by targeting ULK1 ubiquitination in macrophages.
Volume: 34
Issue: 5
Pages: 7144-7159
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Publication
35588785 | J:341702
First Author: Han X
Year: 2022
Journal: J Biol Chem
Title: SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity.
Volume: 298
Issue: 6
Pages: 102036
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Publication
26339226 | J:312063
 
First Author: Alves CJ
Year: 2015
Journal: Front Cell Neurosci
Title: Dysregulated expression of death, stress and mitochondrion related genes in the sciatic nerve of presymptomatic SOD1(G93A) mouse model of Amyotrophic Lateral Sclerosis.
Volume: 9
Pages: 332
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Publication
18523273 | J:137236
First Author: Sabbagh L
Year: 2008
Journal: J Immunol
Title: ERK-dependent Bim modulation downstream of the 4-1BB-TRAF1 signaling axis is a critical mediator of CD8 T cell survival in vivo.
Volume: 180
Issue: 12
Pages: 8093-101
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Publication
16291755 | J:116388
First Author: Eliopoulos AG
Year: 2006
Journal: J Biol Chem
Title: The tyrosine kinase Syk regulates TPL2 activation signals.
Volume: 281
Issue: 3
Pages: 1371-80
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Publication
29619270 | J:274120
 
First Author: Wang T
Year: 2018
Journal: Bone Res
Title: CHIP regulates bone mass by targeting multiple TRAF family members in bone marrow stromal cells.
Volume: 6
Pages: 10
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Publication
19815509 | J:153745
First Author: Liu J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation.
Volume: 106
Issue: 43
Pages: 18279-84
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Publication
20360684 | J:159293
First Author: Chattopadhyay S
Year: 2010
Journal: EMBO J
Title: Viral apoptosis is induced by IRF-3-mediated activation of Bax.
Volume: 29
Issue: 10
Pages: 1762-73
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Publication
31639388 | J:294347
 
First Author: Han S
Year: 2019
Journal: J Mol Cell Cardiol
Title: Sam68 impedes the recovery of arterial injury by augmenting inflammatory response.
Volume: 137
Pages: 82-92
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Publication
24567330 | J:250418
First Author: Kemter E
Year: 2014
Journal: J Biol Chem
Title: No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.
Volume: 289
Issue: 15
Pages: 10715-26
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Publication
29215030 | J:293226
First Author: Zhang R
Year: 2017
Journal: Sci Rep
Title: TRAF3 negatively regulates platelet activation and thrombosis.
Volume: 7
Issue: 1
Pages: 17112
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Publication
32968279 | J:297414
First Author: Xu D
Year: 2020
Journal: Nature
Title: Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.
Volume: 587
Issue: 7832
Pages: 133-138
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Publication
27007849 | J:335612
First Author: Keestra-Gounder AM
Year: 2016
Journal: Nature
Title: NOD1 and NOD2 signalling links ER stress with inflammation.
Volume: 532
Issue: 7599
Pages: 394-7
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Publication
8844497 | J:35208
 
First Author: Pan MG
Journal: J Inflamm
Title: Sequence, genomic organization, and chromosome localization of the mouse TRADD gene.
Volume: 46
Issue: 3
Pages: 168-75
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Publication
12939259 | J:86570
First Author: Pantano C
Year: 2003
Journal: J Biol Chem
Title: Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase.
Volume: 278
Issue: 45
Pages: 44091-6
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Publication
15494504 | J:93747
First Author: Xie P
Year: 2004
Journal: J Immunol
Title: Roles of TNF receptor-associated factor 3 in signaling to B lymphocytes by carboxyl-terminal activating regions 1 and 2 of the EBV-encoded oncoprotein latent membrane protein 1.
Volume: 173
Issue: 9
Pages: 5546-55
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Publication
15469942 | J:95162
First Author: Hu Y
Year: 2004
Journal: J Biol Chem
Title: Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta.
Volume: 279
Issue: 52
Pages: 54387-97
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Publication
16020544 | J:101168
First Author: Grech AP
Year: 2005
Journal: J Biol Chem
Title: Tumor necrosis factor receptor 2 (TNFR2) signaling is negatively regulated by a novel, carboxyl-terminal TNFR-associated factor 2 (TRAF2)-binding site.
Volume: 280
Issue: 36
Pages: 31572-81
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Publication
16115877 | J:102907
First Author: Cusson-Hermance N
Year: 2005
Journal: J Biol Chem
Title: Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.
Volume: 280
Issue: 44
Pages: 36560-6
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Publication
17306544 | J:120727
First Author: O'Donnell MA
Year: 2007
Journal: Curr Biol
Title: Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling.
Volume: 17
Issue: 5
Pages: 418-24
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Publication
17287209 | J:121164
First Author: Noels H
Year: 2007
Journal: J Biol Chem
Title: A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.
Volume: 282
Issue: 14
Pages: 10180-9
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Publication
17878362 | J:152345
First Author: Rowland SL
Year: 2007
Journal: J Immunol
Title: A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling.
Volume: 179
Issue: 7
Pages: 4645-53
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Publication
21268004 | J:175429
First Author: Twu YC
Year: 2011
Journal: Eur J Immunol
Title: TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells.
Volume: 41
Issue: 2
Pages: 335-44
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Publication
21829693 | J:176524
First Author: Hostager BS
Year: 2011
Journal: PLoS One
Title: HOIL-1L interacting protein (HOIP) is essential for CD40 signaling.
Volume: 6
Issue: 8
Pages: e23061
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Publication
23135911 | J:194114
First Author: Hibino T
Year: 2013
Journal: Cancer Res
Title: S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis.
Volume: 73
Issue: 1
Pages: 172-83
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Publication
23608757 | J:198829
First Author: Chung JY
Year: 2013
Journal: Lab Invest
Title: Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity.
Volume: 93
Issue: 6
Pages: 663-76
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Publication
22685329 | J:198887
First Author: Hupalowska A
Year: 2012
Journal: J Cell Sci
Title: APPL1 regulates basal NF-κB activity by stabilizing NIK.
Volume: 125
Issue: Pt 17
Pages: 4090-102
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Publication
27122189 | J:246811
First Author: Brown M
Year: 2016
Journal: J Cell Sci
Title: An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.
Volume: 129
Issue: 12
Pages: 2317-2328
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Publication
19880804 | J:346181
First Author: Burchfield JS
Year: 2010
Journal: Circ Heart Fail
Title: The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart.
Volume: 3
Issue: 1
Pages: 157-64
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Protein
A0A0A6YXC4
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Publication
12040173 | -
First Author: Chen G
Year: 2002
Journal: Science
Title: TNF-R1 signaling: a beautiful pathway.
Volume: 296
Issue: 5573
Pages: 1634-5
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Publication
22374304 | -
First Author: Cabal-Hierro L
Year: 2012
Journal: Cell Signal
Title: Signal transduction by tumor necrosis factor receptors.
Volume: 24
Issue: 6
Pages: 1297-305
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Publication
12387856 | -
First Author: Sunnerhagen M
Year: 2002
Journal: FEBS Lett
Title: The new MATH: homology suggests shared binding surfaces in meprin tetramers and TRAF trimers.
Volume: 530
Issue: 1-3
Pages: 1-3
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Publication
7890660 | -
First Author: Marchand P
Year: 1995
Journal: J Biol Chem
Title: COOH-terminal proteolytic processing of secreted and membrane forms of the alpha subunit of the metalloprotease meprin A. Requirement of the I domain for processing in the endoplasmic reticulum.
Volume: 270
Issue: 10
Pages: 5449-56
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Publication
26359318 | -
First Author: Han BK
Year: 2016
Journal: Semin Arthritis Rheum
Title: The CD27-CD70 pathway and pathogenesis of autoimmune disease.
Volume: 45
Issue: 4
Pages: 496-501
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Protein Domain
IPR002083 | MATH/TRAF_dom
Type: Domain
Description: Although apparently functionally unrelated, intracellular TRAFs and extracellular meprins share a conserved region of about 180 residues, the meprin and TRAF homology (MATH) domain []. Meprins are mammalian tissue-specific metalloendopeptidases of the astacin family implicated in developmental, normal and pathological processes by hydrolysing a variety of proteins. Various growth factors, cytokines, and extracellular matrix proteins are substrates for meprins. They are composed of five structural domains: an N-terminal endopeptidase domain, a MAM domain (see ), a MATH domain, an EGF-like domain (see ) and a C-terminal transmembrane region. Meprin A and B form membrane bound homotetramer whereas homooligomers of meprin A are secreted. A proteolitic site adjacent to the MATH domain, only present in meprin A, allows the release of the protein from the membrane [].TRAF proteins were first isolated by their ability to interact with TNF receptors []. They promote cell survival by the activation of downstream protein kinases and, finally, transcription factors of the NF-kB and AP-1 family. The TRAF proteins are composed of 3 structural domains: a RING finger (see ) in the N-terminal part of the protein, one to seven TRAF zinc fingers (see ) in the middle and the MATH domain in the C-terminal part []. The MATH domain is necessary and sufficient for self-association and receptor interaction. From the structural analysis two consensus sequence recognised by the TRAF domain have been defined: a major one, [PSAT]x[QE]E and a minor one, PxQxxD [].The structure of the TRAF2 protein reveals a trimeric self-association of the MATH domain []. The domain forms a new, light-stranded antiparallel β-sandwich structure. A coiled-coil region adjacent to the MATH domain is also important for the trimerisation. The oligomerisation is essential for establishing appropriate connections to form signalling complexes with TNF receptor-1. The ligand binding surface of TRAF proteins is located in β-strands 6 and 7 [].
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Publication
22536156 | J:195390
First Author: Vrazo AC
Year: 2012
Journal: PLoS Pathog
Title: Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice.
Volume: 8
Issue: 4
Pages: e1002662
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Publication
9366415 | J:43977
First Author: Hsing Y
Year: 1997
Journal: J Immunol
Title: Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes.
Volume: 159
Issue: 10
Pages: 4898-906
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Publication
9620659 | J:55207
First Author: Adam-Klages S
Year: 1998
Journal: J Leukoc Biol
Title: Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.
Volume: 63
Issue: 6
Pages: 678-82
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Publication
37229235 | J:346182
 
First Author: Marshall AG
Year: 2023
Journal: Front Cardiovasc Med
Title: Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart.
Volume: 10
Pages: 1064640
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Publication
37679334 | J:340285
First Author: Vashisht M
Year: 2023
Journal: Cell Death Dis
Title: TRAF2/3 deficient B cells resist DNA damage-induced apoptosis via NF-κB2/XIAP/cIAP2 axis and IAP antagonist sensitizes mutant lymphomas to chemotherapeutic drugs.
Volume: 14
Issue: 9
Pages: 599
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•
Protein
P70191
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
•
•
•
•
•
Protein
Q60803
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
•
•
•
•
•
Protein
Q61382
Organism: Mus musculus/domesticus
Length: 470  
Fragment?: false
•
•
•
•
•
Protein
P70196
Organism: Mus musculus/domesticus
Length: 530  
Fragment?: false
•
•
•
•
•
Protein
Q3UHJ1
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
•
•
•
•
•
Protein
Q3UMS9
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
•
•
•
•
•
Protein
Q3UHM2
Organism: Mus musculus/domesticus
Length: 542  
Fragment?: false
•
•
•
•
•
Protein
F6U5N5
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
•
•
•
•
•
Protein
Q9CXV4
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
•
•
•
•
•
Protein
A0A0A6YXL9
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: false
•
•
•
•
•
Protein
B1ATK6
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: true
•
•
•
•
•
Protein
A0A0A6YWE7
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
•
•
•
•
•
Protein
B1ATK7
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
•
•
•
•
•
Protein
Q571K4
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
•
•
•
•
•
Protein
Q99K90
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
•
•
•
•
•
Protein
B1ASY9
Organism: Mus musculus/domesticus
Length: 716  
Fragment?: false
•
•
•
•
•
Protein Coding Gene
MGI:1346876 | Map3k5
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:1349436 | Ern2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
D3Z343
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
•
•
•
•
•
Protein
P41272
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
•
•
•
•
•
Publication
9177220 | J:117434
First Author: Prasad KV
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.
Volume: 94
Issue: 12
Pages: 6346-51
•
•
•
•
•
Protein
Q8K2V1
Organism: Mus musculus/domesticus
Length: 951  
Fragment?: false
•
•
•
•
•
Protein
P47741
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
•
•
•
•
•
Protein
B1ASL3
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
•
•
•
•
•
Protein
Q3U4X0
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
•
•
•
•
•
Protein
E9PX53
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: false
•
•
•
•
•
Protein
E9QPR5
Organism: Mus musculus/domesticus
Length: 951  
Fragment?: false
•
•
•
•
•
Protein
E0CXK8
Organism: Mus musculus/domesticus
Length: 376  
Fragment?: false
•
•
•
•
•
Protein
F6TLH3
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
•
•
•
•
•
Protein
Q3TLM9
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: false
•
•
•
•
•
Protein
E0CYV2
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
•
•
•
•
•
Protein Coding Gene
MGI:1930134 | Ern1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
28410990 | J:254534
First Author: Gurung P
Year: 2017
Journal: Immunity
Title: Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.
Volume: 46
Issue: 4
Pages: 635-648
•
•
•
•
•
Protein
Q717B4
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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