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Search results 601 to 681 out of 681 for Unc5b

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Type Details Score
Publication
26633881 | J:250766
   
First Author: Poliak S
Year: 2015
Journal: Elife
Title: Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.
Volume: 4
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Publication
26659141 | J:228291
 
First Author: Shinmyo Y
Year: 2015
Journal: Nat Commun
Title: Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.
Volume: 6
Pages: 10232
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Publication
32562661 | J:297714
First Author: Brignani S
Year: 2020
Journal: Neuron
Title: Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.
Volume: 107
Issue: 4
Pages: 684-702.e9
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Publication
37823339 | J:343073
 
First Author: Luo PM
Year: 2023
Journal: Development
Title: Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.
Volume: 150
Issue: 22
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Publication
33951080 | J:306163
First Author: Ji S
Year: 2021
Journal: PLoS One
Title: Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.
Volume: 16
Issue: 5
Pages: e0250669
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Publication
37818607 | J:343095
 
First Author: Honeycutt SE
Year: 2023
Journal: Development
Title: Netrin 1 directs vascular patterning and maturity in the developing kidney.
Volume: 150
Issue: 22
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Publication
32553152 | J:306314
First Author: Maheshwari U
Year: 2020
Journal: Cell Rep
Title: Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets.
Volume: 31
Issue: 11
Pages: 107767
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Publication
22076636 | J:192712
First Author: Meadows SM
Year: 2012
Journal: Circ Res
Title: Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.
Volume: 110
Issue: 1
Pages: 34-46
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Publication
31351040 | J:282348
First Author: Dasgupta K
Year: 2019
Journal: Dev Biol
Title: Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.
Volume: 455
Issue: 2
Pages: 434-448
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Publication
16829211 | J:115165
First Author: Hecht J
Year: 2007
Journal: Gene Expr Patterns
Title: Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model.
Volume: 7
Issue: 1-2
Pages: 102-12
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Publication
16284245 | J:103829
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8K1S3
Organism: Mus musculus/domesticus
Length: 945  
Fragment?: false
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Publication
30286954 | J:273349
First Author: Yang X
Year: 2018
Journal: Biochem Biophys Res Commun
Title: The role of UNC5b in ox-LDL inhibiting migration of RAW264.7 macrophages and the involvement of CCR7.
Volume: 505
Issue: 3
Pages: 637-643
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Protein
Q8K1S3-2
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: false
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Publication
23599441 | J:218868
First Author: Ramkhelawon B
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival.
Volume: 33
Issue: 6
Pages: 1180-8
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Publication
19492039 | -
First Author: Karaulanov E
Year: 2009
Journal: PLoS One
Title: Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos.
Volume: 4
Issue: 5
Pages: e5742
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Publication
17139086 | -
First Author: Handa N
Year: 2006
Journal: Acta Crystallogr D Biol Crystallogr
Title: Structure of the UNC5H2 death domain.
Volume: 62
Issue: Pt 12
Pages: 1502-9
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Publication
19211685 | -
First Author: Wang W
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor.
Volume: 296
Issue: 4
Pages: F723-9
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Publication
19328064 | -
First Author: Wang R
Year: 2009
Journal: Mol Cell
Title: Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor.
Volume: 33
Issue: 6
Pages: 692-703
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Allele
Unc5b<tm1.1(cre/ERT2)Zjh> | MGI:6849725
Name: unc-5 netrin receptor B; targeted mutation 1.1, Z Josh Huang
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:7852509 | STOCK Unc5b<tm1.1(cre/ERT2)Zjh>/J
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Unc5b/Unc5b<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
22405201 | J:224730
First Author: O'Sullivan ML
Year: 2012
Journal: Neuron
Title: FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.
Volume: 73
Issue: 5
Pages: 903-10
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Publication
27681594 | J:314289
First Author: Maruyama K
Year: 2016
Journal: J Biol Chem
Title: Bone-protective Functions of Netrin 1 Protein.
Volume: 291
Issue: 46
Pages: 23854-23868
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Publication
27882935 | J:243065
 
First Author: Zhang F
Year: 2016
Journal: Nat Commun
Title: The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.
Volume: 7
Pages: 13517
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Protein Domain
IPR042156 | Death_UNC5B
Type: Domain
Description: This entry represents the death domain (DD) found in Uncoordinated-5B (UNC5B), which is a receptor for the secreted netrin-1 and plays a role in axonal guidance, angiogenesis, and apoptosis. UNC5B signaling is involved in the netrin-1-induced proliferation and migration of renal proximal tubular cells []. It is also required for vascular patterning during embryonic development, and its activation inhibits sprouting angiogenesis [, ]. It belongs to the UNC-5 family.UNC5 proteins are transmembrane proteins with an extracellular domain consisting of two immunoglobulin repeats, two thrombospondin type-I modules and an intracellular region containing a ZU-5 domain, UPA domain and a DD [, , ].DDs (Death domains) are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including CARD (Caspase activation and recruitment domain), DED (Death Effector Domain), and PYRIN. They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes [, ].
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Publication
20407033 | J:162807
First Author: Larrieu-Lahargue F
Year: 2010
Journal: Blood
Title: Netrin-4 induces lymphangiogenesis in vivo.
Volume: 115
Issue: 26
Pages: 5418-26
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Publication
21799154 | J:188830
First Author: Larrieu-Lahargue F
Year: 2011
Journal: Circ Res
Title: Netrin-4 activates endothelial integrin {alpha}6{beta}1.
Volume: 109
Issue: 7
Pages: 770-4
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Publication
25656845 | J:315541
First Author: Tu T
Year: 2015
Journal: Cell Res
Title: CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development.
Volume: 25
Issue: 3
Pages: 275-87
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Publication
11533026 | -
First Author: Tong J
Year: 2001
Journal: J Biol Chem
Title: Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain.
Volume: 276
Issue: 44
Pages: 40917-25
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Publication
19785719 | -
First Author: Rajasekharan S
Year: 2009
Journal: Genome Biol
Title: The netrin protein family.
Volume: 10
Issue: 9
Pages: 239
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Protein
Q3UH38
Organism: Mus musculus/domesticus
Length: 901  
Fragment?: true
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Protein
Q3TYW6
Organism: Mus musculus/domesticus
Length: 945  
Fragment?: false
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Publication
7482697 | -
First Author: Feinstein E
Year: 1995
Journal: Trends Biochem Sci
Title: The death domain: a module shared by proteins with diverse cellular functions.
Volume: 20
Issue: 9
Pages: 342-4
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Publication
17201679 | -
 
First Author: Park HH
Year: 2007
Journal: Annu Rev Immunol
Title: The death domain superfamily in intracellular signaling of apoptosis and inflammation.
Volume: 25
Pages: 561-86
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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