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Search results 601 to 687 out of 687 for Unc5c

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Type Details Score
Publication
37321213 | J:338207
     
First Author: Moreau MX
Year: 2023
Journal: Dev Cell
Title: Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons.
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Publication
32562661 | J:297714
First Author: Brignani S
Year: 2020
Journal: Neuron
Title: Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.
Volume: 107
Issue: 4
Pages: 684-702.e9
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Publication
24360543 | J:207512
First Author: Escalante A
Year: 2013
Journal: Neuron
Title: Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.
Volume: 80
Issue: 6
Pages: 1392-406
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Publication
37823339 | J:343073
 
First Author: Luo PM
Year: 2023
Journal: Development
Title: Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.
Volume: 150
Issue: 22
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Publication
33951080 | J:306163
First Author: Ji S
Year: 2021
Journal: PLoS One
Title: Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.
Volume: 16
Issue: 5
Pages: e0250669
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Publication
35927240 | J:327333
First Author: Yang KY
Year: 2022
Journal: Cell Death Dis
Title: Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.
Volume: 13
Issue: 8
Pages: 674
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Publication
37818607 | J:343095
 
First Author: Honeycutt SE
Year: 2023
Journal: Development
Title: Netrin 1 directs vascular patterning and maturity in the developing kidney.
Volume: 150
Issue: 22
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Publication
19592574 | J:152847
First Author: Prakash N
Year: 2009
Journal: Development
Title: Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.
Volume: 136
Issue: 15
Pages: 2545-55
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Publication
18480165 | J:136961
First Author: Zhang Y
Year: 2008
Journal: Development
Title: Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.
Volume: 135
Issue: 12
Pages: 2161-72
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Publication
34170322 | J:308818
 
First Author: Moreau MX
Year: 2021
Journal: Development
Title: Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.
Volume: 148
Issue: 14
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Publication
31351040 | J:282348
First Author: Dasgupta K
Year: 2019
Journal: Dev Biol
Title: Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.
Volume: 455
Issue: 2
Pages: 434-448
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Publication
27568519 | J:253351
First Author: Hanley O
Year: 2016
Journal: Neuron
Title: Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.
Volume: 91
Issue: 5
Pages: 1005-1020
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Publication
21150899 | J:167212
First Author: Gibson P
Year: 2010
Journal: Nature
Title: Subtypes of medulloblastoma have distinct developmental origins.
Volume: 468
Issue: 7327
Pages: 1095-9
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Publication
35831953 | J:327901
 
First Author: Ye Q
Year: 2022
Journal: Development
Title: Understanding the development of oral epithelial organs through single cell transcriptomic analysis.
Volume: 149
Issue: 16
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
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Publication
9782087 | J:50367
First Author: Ackerman SL
Year: 1998
Journal: Genomics
Title: Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23.
Volume: 52
Issue: 2
Pages: 205-8
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Publication
16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
24154525 | J:205051
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
O08747
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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Protein
O08747-2
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: false
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GXD Expression
GXD Expression
 
Probe: MGI:4830304
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6258913
Age: embryonic day 15.5
Note: There was no colocalization with Unc5c staining.
Specimen Label: 5e
Detected: true
Specimen Num: 2
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Publication
11533026 | -
First Author: Tong J
Year: 2001
Journal: J Biol Chem
Title: Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain.
Volume: 276
Issue: 44
Pages: 40917-25
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Publication
20032384 | -
First Author: Hibi K
Year: 2009
Journal: Anticancer Res
Title: Changes in UNC5C gene methylation during human gastric carcinogenesis.
Volume: 29
Issue: 11
Pages: 4397-9
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Allele
Unc5c<em2Smoc> | MGI:7293074
Name: unc-5 netrin receptor C; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718310 | C57BL/6JSmoc-Unc5c<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Unc5c<em1Smoc> | MGI:7293073
Name: unc-5 netrin receptor C; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Unc5c<rcmTg(Ucp)1.23Kz> | MGI:1857852
 
Name: unc-5 netrin receptor C; rostral cerebellar malformation (Tg(Ucp)1.23Kz)
Allele Type: Transgenic
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Allele
Unc5c<rcmTg(Tert)5Hwl> | MGI:2678074
 
Name: unc-5 netrin receptor C; transgene insertion 5, Han-Woong Lee
Allele Type: Transgenic
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Strain
MGI:7623527 | C57BL/6JSmoc-Unc5c<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR042154 | Death_UNC5C
Type: Domain
Description: This entry represents the death domain (DD) found in Uncoordinated-5C (UNC5C), which is a receptor for the secreted netrin-1 and plays a role in axonal guidance, angiogenesis, and apoptosis. It belongs to the UNC-5 family. UNC5C plays a critical role in the development of spinal accessory motor neurons []. Methylation of the UNC5C gene is associated with early stages of colorectal carcinogenesis [, ].UNC5 proteins are transmembrane proteins with an extracellular domain consisting of two immunoglobulin repeats, two thrombospondin type-I modules and an intracellular region containing a ZU-5 domain, UPA domain and a DD [, , ].DDs (Death domains) are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including CARD (Caspase activation and recruitment domain), DED (Death Effector Domain), and PYRIN. They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes [, ].
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Publication
22405201 | J:224730
First Author: O'Sullivan ML
Year: 2012
Journal: Neuron
Title: FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.
Volume: 73
Issue: 5
Pages: 903-10
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Strain
MGI:3665491 | B6.Cg-Unc5c<rcmTg(Ucp)1.23Kz>
Attribute String: transgenic, mutant strain, congenic
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Allele
Flrt2<em1Jnk> | MGI:7505615
 
Name: fibronectin leucine rich transmembrane protein 2; endonuclease-mediated mutation 1, Jeremy Kay
Allele Type: Endonuclease-mediated
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Genotype
Genotype
Symbol: Unc5c/Unc5c
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Unc5c/Unc5c
Background: B6.Cg-Unc5c
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Unc5c/Unc5c
Background: involves: C57BL/6J * SJL/J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7505616 | B6.Cg-Flrt2<em1Jnk>/J
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Dcc/Dcc<+> Unc5c/Unc5c<+>
Background: involves: 129X1/SvJ * C57BL/6J * SJL/J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dcc/Dcc<+> Unc5c/Unc5c
Background: involves: 129X1/SvJ * C57BL/6J * SJL/J
Zygosity: cx
Has Mutant Allele: true
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Publication
22454401 | J:210503
First Author: Heiliger KJ
Year: 2012
Journal: Endocr Relat Cancer
Title: Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.
Volume: 19
Issue: 3
Pages: 409-21
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Publication
9126742 | J:41532
First Author: Leonardo ED
Year: 1997
Journal: Nature
Title: Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors.
Volume: 386
Issue: 6627
Pages: 833-8
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Publication
19785719 | -
First Author: Rajasekharan S
Year: 2009
Journal: Genome Biol
Title: The netrin protein family.
Volume: 10
Issue: 9
Pages: 239
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Publication
36266461 | J:330633
First Author: Shao A
Year: 2022
Journal: Sci Rep
Title: Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney.
Volume: 12
Issue: 1
Pages: 17586
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Protein
Q3UQ08
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: false
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Protein
Q3URW2
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: false
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Protein
E9PVI4
Organism: Mus musculus/domesticus
Length: 876  
Fragment?: false
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Protein
Q3TPN7
Organism: Mus musculus/domesticus
Length: 876  
Fragment?: false
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Publication
7482697 | -
First Author: Feinstein E
Year: 1995
Journal: Trends Biochem Sci
Title: The death domain: a module shared by proteins with diverse cellular functions.
Volume: 20
Issue: 9
Pages: 342-4
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Publication
17201679 | -
 
First Author: Park HH
Year: 2007
Journal: Annu Rev Immunol
Title: The death domain superfamily in intracellular signaling of apoptosis and inflammation.
Volume: 25
Pages: 561-86
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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