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Search results 6001 to 6100 out of 7122 for App

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Type Details Score
Publication
First Author: To AW
Year: 2011
Journal: PLoS One
Title: The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice.
Volume: 6
Issue: 2
Pages: e16991
Publication
First Author: Jung YY
Year: 2018
Journal: Theranostics
Title: Atherosclerosis is exacerbated by chitinase-3-like-1 in amyloid precursor protein transgenic mice.
Volume: 8
Issue: 3
Pages: 749-766
Publication
First Author: Austin SA
Year: 2010
Journal: Circ Res
Title: Endothelial nitric oxide modulates expression and processing of amyloid precursor protein.
Volume: 107
Issue: 12
Pages: 1498-502
Publication
First Author: Xia W
Year: 1998
Journal: Biochemistry
Title: Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Volume: 37
Issue: 47
Pages: 16465-71
Publication  
First Author: Davis SA
Year: 2017
Journal: Neurobiol Dis
Title: TDP-43 expression influences amyloidβ plaque deposition and tau aggregation.
Volume: 103
Pages: 154-162
Publication
First Author: Yuyama K
Year: 2022
Journal: Alzheimers Res Ther
Title: Immuno-digital invasive cleavage assay for analyzing Alzheimer's amyloid ß-bound extracellular vesicles.
Volume: 14
Issue: 1
Pages: 140
Publication  
First Author: Li L
Year: 2021
Journal: Front Physiol
Title: Impaired Hippocampal Neurovascular Coupling in a Mouse Model of Alzheimer's Disease.
Volume: 12
Pages: 715446
Publication
First Author: Zhang J
Year: 2010
Journal: Behav Brain Res
Title: Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience.
Volume: 206
Issue: 2
Pages: 202-7
Publication
First Author: Maesako M
Year: 2013
Journal: PLoS One
Title: Continuation of exercise is necessary to inhibit high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice.
Volume: 8
Issue: 9
Pages: e72796
Publication
First Author: Koppel J
Year: 2013
Journal: Mol Med
Title: CBâ‚‚ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 357-64
Publication
First Author: Koppel J
Year: 2014
Journal: Mol Med
Title: CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.
Volume: 20
Issue: 1
Pages: 29-36
Publication  
First Author: Kitaguchi H
Year: 2009
Journal: Brain Res
Title: Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwInd transgenic mice.
Volume: 1294
Pages: 202-10
Publication
First Author: Wu Y
Year: 2021
Journal: PLoS One
Title: The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model.
Volume: 16
Issue: 7
Pages: e0242236
Publication
First Author: Chintapaludi SR
Year: 2020
Journal: J Alzheimers Dis
Title: Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling.
Volume: 73
Issue: 4
Pages: 1421-1434
Publication
First Author: Kolonics A
Year: 2023
Journal: BMC Neurosci
Title: Exercise combined with postbiotics treatment results in synergistic improvement of mitochondrial function in the brain of male transgenic mice for Alzheimer's disease.
Volume: 24
Issue: 1
Pages: 68
Publication
First Author: Sheng JG
Year: 2002
Journal: J Neurosci
Title: Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.
Volume: 22
Issue: 22
Pages: 9794-9
Publication
First Author: KÃ¥gedal K
Year: 2010
Journal: Biochim Biophys Acta
Title: Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease.
Volume: 1801
Issue: 8
Pages: 831-8
Publication  
First Author: Perez Garcia G
Year: 2023
Journal: Front Dement
Title: Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model.
Volume: 2
Pages: 1198006
Publication  
First Author: McClean PL
Year: 2014
Journal: Neuropharmacology
Title: Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease.
Volume: 76 Pt A
Pages: 57-67
Publication  
First Author: Wang J
Year: 2024
Journal: Front Aging Neurosci
Title: ACOT7, a candidate and novel serum biomarker of Alzheimer's disease.
Volume: 16
Pages: 1345668
Publication  
First Author: Várhelyi ZP
Year: 2017
Journal: Front Neurosci
Title: Adiponectin Receptors Are Less Sensitive to Stress in a Transgenic Mouse Model of Alzheimer's Disease.
Volume: 11
Pages: 199
Publication  
First Author: Li J
Year: 2018
Journal: Front Aging Neurosci
Title: Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer's Disease.
Volume: 10
Pages: 85
Publication  
First Author: De la Rosa-Prieto C
Year: 2016
Journal: Front Neurosci
Title: Neurogenesis, Neurodegeneration, Interneuron Vulnerability, and Amyloid-β in the Olfactory Bulb of APP/PS1 Mouse Model of Alzheimer's Disease.
Volume: 10
Pages: 227
Publication
First Author: Cao K
Year: 2019
Journal: Alzheimers Res Ther
Title: Exposure to fluoride aggravates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation.
Volume: 11
Issue: 1
Pages: 35
Publication  
First Author: Lin TW
Year: 2015
Journal: Neurobiol Learn Mem
Title: Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice.
Volume: 118
Pages: 189-97
Publication
First Author: Dumanis SB
Year: 2015
Journal: J Neurosci
Title: Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.
Volume: 35
Issue: 37
Pages: 12703-13
Publication  
First Author: Baltissen D
Year: 2023
Journal: Front Cell Neurosci
Title: APPsα rescues CDK5 and GSK3β dysregulation and restores normal spine density in Tau transgenic mice.
Volume: 17
Pages: 1106176
Publication  
First Author: Madhoun S
Year: 2023
Journal: Exp Eye Res
Title: Effects of experimental glaucoma in Lama1(nmf223) mutant mice.
Volume: 226
Pages: 109341
Publication
First Author: Ash ES
Year: 2010
Journal: Neurochem Int
Title: Neurochemical changes in a double transgenic mouse model of Alzheimer's disease fed a pro-oxidant diet.
Volume: 57
Issue: 5
Pages: 504-11
Publication
First Author: Henderson BW
Year: 2016
Journal: J Neurochem
Title: Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain.
Volume: 138
Issue: 4
Pages: 525-31
Publication  
First Author: Liu Y
Year: 2019
Journal: Eur J Pharmacol
Title: MicroRNA-128 knockout inhibits the development of Alzheimer's disease by targeting PPARγ in mouse models.
Volume: 843
Pages: 134-144
Publication
First Author: Fraering PC
Year: 2004
Journal: Biochemistry
Title: Purification and characterization of the human gamma-secretase complex.
Volume: 43
Issue: 30
Pages: 9774-89
Publication
First Author: Keil U
Year: 2004
Journal: J Biol Chem
Title: Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis.
Volume: 279
Issue: 48
Pages: 50310-20
Publication
First Author: Bruni P
Year: 2002
Journal: J Biol Chem
Title: Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression.
Volume: 277
Issue: 38
Pages: 35481-8
Publication
First Author: Broder C
Year: 2013
Journal: Biochem J
Title: The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis.
Volume: 450
Issue: 2
Pages: 253-64
Publication  
First Author: Liu CG
Year: 2014
Journal: Brain Res
Title: MicroRNA-135a and -200b, potential Biomarkers for Alzheimer׳s disease, regulate β secretase and amyloid precursor protein.
Volume: 1583
Pages: 55-64
Publication  
First Author: Fenrich KK
Year: 2015
Journal: Behav Brain Res
Title: Improved single pellet grasping using automated ad libitum full-time training robot.
Volume: 281
Pages: 137-48
Publication  
First Author: Cimini S
Year: 2016
Journal: Neurobiol Dis
Title: The cell-permeable Aβ1-6A2VTAT(D) peptide reverts synaptopathy induced by Aβ1-42wt.
Volume: 89
Pages: 101-11
Publication
First Author: Panikker P
Year: 2018
Journal: J Neurosci
Title: Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition.
Volume: 38
Issue: 19
Pages: 4569-4583
Publication  
First Author: Giliberto L
Year: 2008
Journal: Mol Neurodegener
Title: Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role.
Volume: 3
Pages: 12
Publication
First Author: Lin FB
Year: 2018
Journal: Nan Fang Yi Ke Da Xue Xue Bao
Title: [Verification of a sporadic Alzheimer disease model in SORL1 gene knockout mice].
Volume: 38
Issue: 3
Pages: 289-295
Publication  
First Author: Jiang M
Year: 2020
Journal: Neurobiol Aging
Title: Amyloid precursor protein intracellular domain-dependent regulation of FOXO3a inhibits adult hippocampal neurogenesis.
Volume: 95
Pages: 250-263
Publication  
First Author: Evans AK
Year: 2020
Journal: Neurobiol Dis
Title: Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease.
Volume: 146
Pages: 105089
Publication
First Author: Melis V
Year: 2015
Journal: Cell Mol Life Sci
Title: Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration.
Volume: 72
Issue: 11
Pages: 2199-222
Publication
First Author: Gammie SC
Year: 2022
Journal: Sci Rep
Title: Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS.
Volume: 12
Issue: 1
Pages: 108
Publication
First Author: Krueger I
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases.
Volume: 40
Issue: 10
Pages: 2391-2403
Publication  
First Author: Bai N
Year: 2022
Journal: Mol Metab
Title: CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue.
Volume: 63
Pages: 101531
Protein
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
Publication
First Author: Tam SJ
Year: 2012
Journal: Dev Cell
Title: Death receptors DR6 and TROY regulate brain vascular development.
Volume: 22
Issue: 2
Pages: 403-17
Protein
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: true
Publication
First Author: Bai XC
Year: 2015
Journal: Nature
Title: An atomic structure of human γ-secretase.
Volume: 525
Issue: 7568
Pages: 212-217
Publication
First Author: Goodwin LO
Year: 2019
Journal: Genome Res
Title: Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis.
Volume: 29
Issue: 3
Pages: 494-505
Publication
First Author: Wang X
Year: 2013
Journal: Nat Med
Title: Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.
Volume: 19
Issue: 4
Pages: 473-80
Strain
Attribute String: chromosome aberration, mutant strain, trisomy
Publication  
First Author: Ravaioli F
Year: 2024
Journal: Front Aging Neurosci
Title: Increased hippocampal epigenetic age in the Ts65Dn mouse model of Down Syndrome.
Volume: 16
Pages: 1401109
Publication
First Author: Sussan TE
Year: 2008
Journal: Nature
Title: Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
Volume: 451
Issue: 7174
Pages: 73-5
Publication
First Author: Ridnour LA
Year: 2012
Journal: J Neurochem
Title: Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.
Volume: 123
Issue: 5
Pages: 736-49
Publication
First Author: Klein SL
Year: 1996
Journal: Physiol Behav
Title: Characterization of sensorimotor performance, reproductive and aggressive behaviors in segmental trisomic 16 (Ts65Dn) mice.
Volume: 60
Issue: 4
Pages: 1159-64
Publication  
First Author: Ash JA
Year: 2014
Journal: Neurobiol Dis
Title: Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice.
Volume: 70
Pages: 32-42
Publication
First Author: Yang A
Year: 2011
Journal: Cancer Res
Title: Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.
Volume: 71
Issue: 10
Pages: 3573-81
Publication
First Author: El Hajjar J
Year: 2019
Journal: Sci Rep
Title: Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Volume: 9
Issue: 1
Pages: 594
Publication  
First Author: Flinn JM
Year: 2014
Journal: Front Aging Neurosci
Title: Spatial memory deficits in a mouse model of late-onset Alzheimer's disease are caused by zinc supplementation and correlate with amyloid-beta levels.
Volume: 6
Pages: 174
Publication
First Author: Fryer JD
Year: 2005
Journal: J Neurosci
Title: Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
Volume: 25
Issue: 11
Pages: 2803-10
Publication
First Author: Deane R
Year: 2005
Journal: J Neurosci
Title: IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.
Volume: 25
Issue: 50
Pages: 11495-503
Publication
First Author: Noll C
Year: 2009
Journal: PLoS One
Title: DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.
Volume: 4
Issue: 10
Pages: e7540
Publication
First Author: Li JG
Year: 2017
Journal: Aging Cell
Title: Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.
Volume: 16
Issue: 2
Pages: 273-280
Publication
First Author: Fryer JD
Year: 2005
Journal: J Biol Chem
Title: The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Volume: 280
Issue: 27
Pages: 25754-9
Publication  
First Author: Ettcheto M
Year: 2015
Journal: Exp Gerontol
Title: Hypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice.
Volume: 65
Pages: 69-78
Publication
First Author: Bengoechea TG
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model.
Volume: 106
Issue: 19
Pages: 7870-5
Publication
First Author: Hutchinson D
Year: 2007
Journal: Neuroscience
Title: Quantitative measurement of postural sway in mouse models of human neurodegenerative disease.
Volume: 148
Issue: 4
Pages: 825-32
Publication
First Author: Wilcock DM
Year: 2009
Journal: Neuroscience
Title: Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease.
Volume: 159
Issue: 3
Pages: 1055-69
Publication
First Author: Colton CA
Year: 2014
Journal: J Neuropathol Exp Neurol
Title: mNos2 deletion and human NOS2 replacement in Alzheimer disease models.
Volume: 73
Issue: 8
Pages: 752-69
Publication
First Author: Colton CA
Year: 2008
Journal: J Alzheimers Dis
Title: The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP.
Volume: 15
Issue: 4
Pages: 571-87
Publication
First Author: Singh N
Year: 2016
Journal: Dev Dyn
Title: Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice.
Volume: 245
Issue: 2
Pages: 114-22
Publication
First Author: Singh N
Year: 2015
Journal: Dis Model Mech
Title: Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology.
Volume: 8
Issue: 3
Pages: 271-9
Publication
First Author: Roper RJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice.
Volume: 103
Issue: 5
Pages: 1452-6
Publication  
First Author: Dutka T
Year: 2015
Journal: Mech Dev
Title: Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.
Volume: 135
Pages: 68-80
Publication
First Author: Kirsammer G
Year: 2008
Journal: Blood
Title: Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.
Volume: 111
Issue: 2
Pages: 767-75
Publication
First Author: Shibuya Y
Year: 2015
Journal: Neurobiol Aging
Title: Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
Volume: 36
Issue: 7
Pages: 2248-2259
Publication
First Author: Matsuki T
Year: 2012
Journal: PLoS One
Title: Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.
Volume: 7
Issue: 2
Pages: e31152
Publication
First Author: Blazek JD
Year: 2011
Journal: Bone
Title: Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.
Volume: 48
Issue: 2
Pages: 275-80
Publication
First Author: Westaway D
Year: 2011
Journal: PLoS Pathog
Title: Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
Volume: 7
Issue: 11
Pages: e1002391
Publication
First Author: Cissé M
Year: 2011
Journal: J Neurosci
Title: Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice.
Volume: 31
Issue: 29
Pages: 10427-31
Publication
First Author: Lane AA
Year: 2014
Journal: Nat Genet
Title: Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
Volume: 46
Issue: 6
Pages: 618-23
Publication  
First Author: Sagare AP
Year: 2013
Journal: Nat Commun
Title: Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Volume: 4
Pages: 2932
Strain
Attribute String: targeted mutation, transgenic, mutant strain, congenic
Publication      
First Author: Campbell K
Year: 2010
Journal: MGI Direct Data Submission
Title: Mice homozygous for a dystroglycan 1 mutation with exon flanked by loxP sites are viable and fertile and appear healthy
Publication
First Author: Caglayan S
Year: 2014
Journal: Sci Transl Med
Title: Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.
Volume: 6
Issue: 223
Pages: 223ra20
Publication
First Author: Kim D
Year: 2007
Journal: EMBO J
Title: SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
Volume: 26
Issue: 13
Pages: 3169-79
Publication
First Author: Koenigsknecht-Talboo J
Year: 2008
Journal: J Neurosci
Title: Rapid microglial response around amyloid pathology after systemic anti-Abeta antibody administration in PDAPP mice.
Volume: 28
Issue: 52
Pages: 14156-64
Publication
First Author: Hurtado DE
Year: 2012
Journal: J Neurosci
Title: Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease.
Volume: 32
Issue: 21
Pages: 7392-402
Publication  
First Author: Janssens J
Year: 2021
Journal: Neurobiol Dis
Title: Passive immunotherapy with a novel antibody against 3pE-modified Aβ demonstrates potential for enhanced efficacy and favorable safety in combination with BACE inhibitor treatment in plaque-depositing mice.
Volume: 154
Pages: 105365
Publication
First Author: Wildsmith KR
Year: 2012
Journal: PLoS One
Title: In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.
Volume: 7
Issue: 6
Pages: e38013
Publication  
First Author: Mably AJ
Year: 2015
Journal: Neurobiol Dis
Title: Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice.
Volume: 82
Pages: 372-384
Publication
First Author: Bott JB
Year: 2013
Journal: Neurobiol Aging
Title: Reduced plasticity and mild cognitive impairment-like deficits after entorhinal lesions in hAPP/APOE4 mice.
Volume: 34
Issue: 11
Pages: 2683-93
Publication
First Author: Bott JB
Year: 2016
Journal: J Neurosci
Title: APOE-Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input.
Volume: 36
Issue: 40
Pages: 10472-10486