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Search results 6001 to 6100 out of 8814 for Clock

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Type Details Score
Publication  
First Author: Yoshida Y
Year: 2024
Journal: Int J Mol Sci
Title: Monocyte/Macrophage-Specific Loss of ARNTL Suppresses Chronic Kidney Disease-Associated Cardiac Impairment.
Volume: 25
Issue: 23
Publication
First Author: Adlanmerini M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold.
Volume: 116
Issue: 37
Pages: 18691-18699
Publication
First Author: Reinke H
Year: 2008
Journal: Genes Dev
Title: Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor.
Volume: 22
Issue: 3
Pages: 331-45
Publication
First Author: Tsujino T
Year: 2005
Journal: Clin Exp Hypertens
Title: Circadian expression of plasminogen activator inhibitor-1 in angiotensin II type 1a receptor knockout mice.
Volume: 27
Issue: 2-3
Pages: 159-68
Publication  
First Author: Hahn J
Year: 2020
Journal: Brain Behav Immun
Title: Sleep enhances numbers and function of monocytes and improves bacterial infection outcome in mice.
Volume: 87
Pages: 329-338
Publication
First Author: Soscia SJ
Year: 2004
Journal: Brain Res
Title: Neuropeptide Y attenuates NMDA-induced phase shifts in the SCN of NPY Y1 receptor knockout mice in vitro.
Volume: 1023
Issue: 1
Pages: 148-53
Publication
First Author: Kosir R
Year: 2012
Journal: PLoS One
Title: Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis.
Volume: 7
Issue: 2
Pages: e31798
Publication
First Author: Schilperoort M
Year: 2019
Journal: Sci Rep
Title: Time-restricted feeding improves adaptation to chronically alternating light-dark cycles.
Volume: 9
Issue: 1
Pages: 7874
Publication
First Author: Nakazato R
Year: 2017
Journal: J Neurosci
Title: Disruption of Bmal1 Impairs Blood-Brain Barrier Integrity via Pericyte Dysfunction.
Volume: 37
Issue: 42
Pages: 10052-10062
Publication
First Author: Yang G
Year: 2012
Journal: PLoS One
Title: Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism.
Volume: 7
Issue: 8
Pages: e38117
Publication
First Author: Hundahl CA
Year: 2012
Journal: PLoS One
Title: Circadian behaviour in neuroglobin deficient mice.
Volume: 7
Issue: 4
Pages: e34462
Publication  
First Author: Roy S
Year: 2022
Journal: Endocrinology
Title: Androgen-mediated Perturbation of the Hepatic Circadian System Through Epigenetic Modulation Promotes NAFLD in PCOS Mice.
Volume: 163
Issue: 10
Publication
First Author: Maekawa F
Year: 2012
Journal: Epigenetics
Title: Diurnal expression of Dnmt3b mRNA in mouse liver is regulated by feeding and hepatic clockwork.
Volume: 7
Issue: 9
Pages: 1046-56
Publication
First Author: Zhang D
Year: 2018
Journal: Hepatology
Title: The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARα pathway.
Volume: 68
Issue: 3
Pages: 883-896
Publication
First Author: Tonsfeldt KJ
Year: 2019
Journal: J Endocr Soc
Title: The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge.
Volume: 3
Issue: 4
Pages: 716-733
Publication  
First Author: Kim H
Year: 2021
Journal: Mol Metab
Title: Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.
Volume: 49
Pages: 101192
Publication
First Author: Hoffmann HM
Year: 2021
Journal: J Neurosci Res
Title: The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice.
Volume: 99
Issue: 10
Pages: 2625-2645
Publication
First Author: Pozdeyev N
Year: 2008
Journal: Eur J Neurosci
Title: Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina.
Volume: 27
Issue: 10
Pages: 2691-700
Publication  
First Author: Lebedeva M
Year: 2024
Journal: Brain Res
Title: The disruption of circadian rhythmicity of gene expression in the hippocampus and associated structures in Gria2(R/R) mice; a comparison with C57BL/6J and Adar2(-/-) mice strains.
Volume: 1826
Pages: 148739
Publication
First Author: Rakai BD
Year: 2014
Journal: PLoS One
Title: Survival of adult generated hippocampal neurons is altered in circadian arrhythmic mice.
Volume: 9
Issue: 6
Pages: e99527
Publication  
First Author: Hemmeryckx B
Year: 2019
Journal: Exp Gerontol
Title: Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis.
Volume: 118
Pages: 1-8
Publication
First Author: Slomnicki LP
Year: 2020
Journal: Sci Rep
Title: Improved locomotor recovery after contusive spinal cord injury in Bmal1-/- mice is associated with protection of the blood spinal cord barrier.
Volume: 10
Issue: 1
Pages: 14212
Publication  
First Author: Sato S
Year: 2020
Journal: Neuroscience
Title: Homer1a Undergoes Bimodal Transcriptional Regulation by CREB and the Circadian Clock.
Volume: 434
Pages: 161-170
Publication      
First Author: Bell BJ
Year: 2020
Journal: bioRxiv
Title: A clock-driven neural network critical for arousal.
Publication  
First Author: Zhu B
Year: 2023
Journal: Front Physiol
Title: Preservation of ∼12-h ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock.
Volume: 14
Pages: 1195001
Publication
First Author: Chatterjee S
Year: 2015
Journal: Exp Cell Res
Title: Brain and muscle Arnt-like 1 promotes skeletal muscle regeneration through satellite cell expansion.
Volume: 331
Issue: 1
Pages: 200-10
Publication
First Author: Lefta M
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Development of dilated cardiomyopathy in Bmal1-deficient mice.
Volume: 303
Issue: 4
Pages: H475-85
Publication
First Author: Ratajczak CK
Year: 2009
Journal: Endocrinology
Title: Impaired steroidogenesis and implantation failure in Bmal1-/- mice.
Volume: 150
Issue: 4
Pages: 1879-85
Publication  
First Author: Lembach A
Year: 2018
Journal: Int J Mol Sci
Title: Sex-Dependent Effects of Bmal1-Deficiency on Mouse Cerebral Cortex Infarction in Response to Photothrombotic Stroke.
Volume: 19
Issue: 10
Publication
First Author: Cai W
Year: 2008
Journal: Mol Cell Biol
Title: Expression levels of estrogen receptor beta are modulated by components of the molecular clock.
Volume: 28
Issue: 2
Pages: 784-93
Publication
First Author: Loganathan N
Year: 2019
Journal: Endocrinology
Title: Bisphenol A Alters Bmal1, Per2, and Rev-Erba mRNA and Requires Bmal1 to Increase Neuropeptide Y Expression in Hypothalamic Neurons.
Volume: 160
Issue: 1
Pages: 181-192
Publication
First Author: Petrenko V
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis.
Volume: 117
Issue: 5
Pages: 2484-2495
Publication
First Author: Geyfman M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis.
Volume: 109
Issue: 29
Pages: 11758-63
Publication
First Author: Lemos DR
Year: 2007
Journal: Endocrinology
Title: Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock.
Volume: 148
Issue: 12
Pages: 5811-21
Publication  
First Author: Chen L
Year: 2020
Journal: Front Cell Infect Microbiol
Title: Bmal1 Regulates Coagulation Factor Biosynthesis in Mouse Liver in Streptococcus oralis Infection.
Volume: 10
Pages: 530190
Publication
First Author: Hemmeryckx B
Year: 2012
Journal: Exp Gerontol
Title: Effect of premature aging on murine adipose tissue.
Volume: 47
Issue: 3
Pages: 256-62
Publication
First Author: Hannibal J
Year: 2010
Journal: Eur J Neurosci
Title: Cholecystokinin (CCK)-expressing neurons in the suprachiasmatic nucleus: innervation, light responsiveness and entrainment in CCK-deficient mice.
Volume: 32
Issue: 6
Pages: 1006-17
Publication
First Author: Rovsing L
Year: 2013
Journal: J Comp Neurol
Title: Hypothalamic neurosecretory and circadian vasopressinergic neuronal systems in the blind cone-rod homeobox knockout mouse (Crx-/-) and the 129sv wild-type mouse.
Volume: 521
Issue: 17
Pages: 4061-74
Publication
First Author: Doyle SE
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinal pathways influence temporal niche.
Volume: 105
Issue: 35
Pages: 13133-8
Publication  
First Author: Falk HJ
Year: 2022
Journal: Development
Title: Imaging the onset of oscillatory signaling dynamics during mouse embryo gastrulation.
Volume: 149
Issue: 13
Publication
First Author: Sasaki H
Year: 2020
Journal: Anat Rec (Hoboken)
Title: Neuronal PAS Domain 2 (Npas2)-Deficient Fibroblasts Accelerate Skin Wound Healing and Dermal Collagen Reconstruction.
Volume: 303
Issue: 6
Pages: 1630-1641
Publication
First Author: Ozburn AR
Year: 2015
Journal: Biol Psychiatry
Title: Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2.
Volume: 77
Issue: 5
Pages: 425-433
Publication
First Author: Hassan N
Year: 2017
Journal: PLoS One
Title: Titanium biomaterials with complex surfaces induced aberrant peripheral circadian rhythms in bone marrow mesenchymal stromal cells.
Volume: 12
Issue: 8
Pages: e0183359
Publication
First Author: Falcon E
Year: 2013
Journal: PLoS One
Title: Differential regulation of the period genes in striatal regions following cocaine exposure.
Volume: 8
Issue: 6
Pages: e66438
Publication
First Author: Hughes AT
Year: 2008
Journal: J Neurochem
Title: Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2-/- mice.
Volume: 106
Issue: 4
Pages: 1646-57
Publication
First Author: Harrington M
Year: 2007
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Behavioral and neurochemical sources of variability of circadian period and phase: studies of circadian rhythms of npy-/- mice.
Volume: 292
Issue: 3
Pages: R1306-14
Publication
First Author: Rozov SV
Year: 2015
Journal: PLoS One
Title: On the Role of Histamine Receptors in the Regulation of Circadian Rhythms.
Volume: 10
Issue: 12
Pages: e0144694
Publication
First Author: Yan L
Year: 2006
Journal: J Neurosci
Title: DARPP-32 involvement in the photic pathway of the circadian system.
Volume: 26
Issue: 37
Pages: 9434-8
Publication
First Author: Franken P
Year: 2000
Journal: J Neurosci
Title: The transcription factor DBP affects circadian sleep consolidation and rhythmic EEG activity.
Volume: 20
Issue: 2
Pages: 617-25
Publication  
First Author: Campbell JR
Year: 2020
Journal: Endocrinology
Title: Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion.
Volume: 161
Issue: 5
Publication  
First Author: Ling Z
Year: 2024
Journal: Neuropharmacology
Title: Protective role of madecassoside from Centella asiatica against protein L-isoaspartyl methyltransferase deficiency-induced neurodegeneration.
Volume: 246
Pages: 109834
Publication
First Author: Sundaram S
Year: 2019
Journal: Sci Rep
Title: Inhibition of casein kinase 1δ/εimproves cognitive-affective behavior and reduces amyloid load in the APP-PS1 mouse model of Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 13743
Publication
First Author: Young ME
Year: 2014
Journal: J Biol Rhythms
Title: Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart.
Volume: 29
Issue: 4
Pages: 257-76
Publication
First Author: Schroder EA
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility.
Volume: 304
Issue: 10
Pages: C954-65
Publication
First Author: Mia S
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: Differential effects of REV-ERBα/β agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption.
Volume: 318
Issue: 6
Pages: H1487-H1508
Publication  
First Author: Li H
Year: 2022
Journal: Front Cardiovasc Med
Title: SR9009 improves heart function after pressure overload independent of cardiac REV-ERB.
Volume: 9
Pages: 952114
Publication
First Author: Morton AJ
Year: 2005
Journal: J Neurosci
Title: Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease.
Volume: 25
Issue: 1
Pages: 157-63
Publication
First Author: Pallier PN
Year: 2007
Journal: J Neurosci
Title: Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington's disease.
Volume: 27
Issue: 29
Pages: 7869-78
Publication  
First Author: Ouk K
Year: 2019
Journal: eNeuro
Title: Abnormal Photic Entrainment to Phase-Delaying Stimuli in the R6/2 Mouse Model of Huntington's Disease, despite Retinal Responsiveness to Light.
Volume: 6
Issue: 6
Publication
First Author: Yi SA
Year: 2022
Journal: Exp Mol Med
Title: S6K1 controls adiponectin expression by inducing a transcriptional switch: BMAL1-to-EZH2.
Volume: 54
Issue: 3
Pages: 324-333
Publication
First Author: Mouland JW
Year: 2019
Journal: Curr Biol
Title: Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.
Volume: 29
Issue: 24
Pages: 4260-4267.e4
Publication  
First Author: Ma Z
Year: 2022
Journal: Neurobiol Dis
Title: Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms.
Volume: 168
Pages: 105690
Publication  
First Author: Partington HS
Year: 2021
Journal: Behav Brain Res
Title: Nurr1 deficiency shortens free running period, enhances photoentrainment to phase advance, and disrupts circadian cycling of the dopamine neuron phenotype.
Volume: 411
Pages: 113347
Publication
First Author: Suzuki T
Year: 2001
Journal: Mamm Genome
Title: Quantitative trait locus analysis of abnormal circadian period in CS mice.
Volume: 12
Issue: 4
Pages: 272-7
Publication  
First Author: Ko FC
Year: 2023
Journal: Bone
Title: Colon epithelial cell-specific Bmal1 deletion impairs bone formation in mice.
Volume: 168
Pages: 116650
Publication
First Author: Um JH
Year: 2011
Journal: PLoS One
Title: AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.
Volume: 6
Issue: 3
Pages: e18450
Publication
First Author: Ait-Hmyed Hakkari O
Year: 2016
Journal: FASEB J
Title: Rev-Erbα modulates retinal visual processing and behavioral responses to light.
Volume: 30
Issue: 11
Pages: 3690-3701
Publication
First Author: Lee J
Year: 2020
Journal: Aging Cell
Title: Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
Volume: 19
Issue: 2
Pages: e13078
Publication  
First Author: Sato S
Year: 2014
Journal: ScientificWorldJournal
Title: Direct and indirect suppression of interleukin-6 gene expression in murine macrophages by nuclear orphan receptor REV-ERBα.
Volume: 2014
Pages: 685854
Publication
First Author: Jager J
Year: 2014
Journal: Mol Endocrinol
Title: Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα.
Volume: 28
Issue: 4
Pages: 490-8
Publication  
First Author: Chen R
Year: 2023
Journal: Brain Behav Immun
Title: Microglia depletion ameliorates neuroinflammation, anxiety-like behavior, and cognitive deficits in a sex-specific manner in Rev-erbα knockout mice.
Volume: 114
Pages: 287-298
Publication
First Author: Berthier A
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex.
Volume: 115
Issue: 47
Pages: E11033-E11042
Publication
First Author: Mrosovsky N
Year: 2003
Journal: Chronobiol Int
Title: Impaired masking responses to light in melanopsin-knockout mice.
Volume: 20
Issue: 6
Pages: 989-99
Publication  
First Author: Tam SKE
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory.
Volume: 118
Issue: 39
Publication
First Author: Stein RM
Year: 2020
Journal: Nature
Title: Virtual discovery of melatonin receptor ligands to modulate circadian rhythms.
Volume: 579
Issue: 7800
Pages: 609-614
Publication
First Author: Owino S
Year: 2016
Journal: PLoS One
Title: Melatonin Signaling Controls the Daily Rhythm in Blood Glucose Levels Independent of Peripheral Clocks.
Volume: 11
Issue: 1
Pages: e0148214
Publication
First Author: Delezie J
Year: 2012
Journal: FASEB J
Title: The nuclear receptor REV-ERBα is required for the daily balance of carbohydrate and lipid metabolism.
Volume: 26
Issue: 8
Pages: 3321-35
Publication  
First Author: Delezie J
Year: 2016
Journal: Sci Rep
Title: Rev-erbα in the brain is essential for circadian food entrainment.
Volume: 6
Pages: 29386
Publication
First Author: Paerewijck O
Year: 2017
Journal: Sci Rep
Title: Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia.
Volume: 7
Issue: 1
Pages: 8520
Publication  
First Author: Pastore N
Year: 2019
Journal: EMBO J
Title: Nutrient-sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock.
Volume: 38
Issue: 12
Publication
First Author: Imamura K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASK family kinases mediate cellular stress and redox signaling to circadian clock.
Volume: 115
Issue: 14
Pages: 3646-3651
Publication  
First Author: Schroder EA
Year: 2021
Journal: Front Physiol
Title: Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a +/ΔKPQ Mice.
Volume: 12
Pages: 681011
Publication  
First Author: Crislip GR
Year: 2022
Journal: Biomolecules
Title: Apparent Absence of BMAL1-Dependent Skeletal Muscle-Kidney Cross Talk in Mice.
Volume: 12
Issue: 2
Publication
First Author: Schroeder A
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Circadian regulation of cardiovascular function: a role for vasoactive intestinal peptide.
Volume: 300
Issue: 1
Pages: H241-50
Publication
First Author: Brown TM
Year: 2007
Journal: J Neurophysiol
Title: Disrupted neuronal activity rhythms in the suprachiasmatic nuclei of vasoactive intestinal polypeptide-deficient mice.
Volume: 97
Issue: 3
Pages: 2553-8
Publication
First Author: Dragich JM
Year: 2010
Journal: Eur J Neurosci
Title: The role of the neuropeptides PACAP and VIP in the photic regulation of gene expression in the suprachiasmatic nucleus.
Volume: 31
Issue: 5
Pages: 864-75
Publication
First Author: Vieira E
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.
Volume: 295
Issue: 5
Pages: E1032-7
Publication
First Author: Yamaguchi Y
Year: 2022
Journal: Biol Pharm Bull
Title: Nmu/Nms/Gpr176 Triple-Deficient Mice Show Enhanced Light-Resetting of Circadian Locomotor Activity.
Volume: 45
Issue: 8
Pages: 1172-1179
Publication
First Author: Riedel CS
Year: 2020
Journal: PLoS One
Title: Altered light induced EGR1 expression in the SCN of PACAP deficient mice.
Volume: 15
Issue: 5
Pages: e0232748
Publication  
First Author: Hablitz LM
Year: 2020
Journal: eNeuro
Title: Cannabinoid Signaling Recruits Astrocytes to Modulate Presynaptic Function in the Suprachiasmatic Nucleus.
Volume: 7
Issue: 1
Publication
First Author: Kudo T
Year: 2011
Journal: Exp Neurol
Title: Circadian dysfunction in a mouse model of Parkinson's disease.
Volume: 232
Issue: 1
Pages: 66-75
Publication
First Author: Hughes AT
Year: 2004
Journal: J Neurosci
Title: Aberrant gating of photic input to the suprachiasmatic circadian pacemaker of mice lacking the VPAC2 receptor.
Volume: 24
Issue: 14
Pages: 3522-6
Publication
First Author: Sheward WJ
Year: 2010
Journal: PLoS One
Title: Circadian control of mouse heart rate and blood pressure by the suprachiasmatic nuclei: behavioral effects are more significant than direct outputs.
Volume: 5
Issue: 3
Pages: e9783
Publication
First Author: Cao R
Year: 2013
Journal: Eur J Neurosci
Title: Mitogen- and stress-activated protein kinase 1 modulates photic entrainment of the suprachiasmatic circadian clock.
Volume: 37
Issue: 1
Pages: 130-40
Publication  
First Author: Ono M
Year: 2022
Journal: Int J Mol Sci
Title: Uterine Deletion of Bmal1 Impairs Placental Vascularization and Induces Intrauterine Fetal Death in Mice.
Volume: 23
Issue: 14
Publication
First Author: Chatterjee S
Year: 2020
Journal: BMC Biol
Title: The CBP KIX domain regulates long-term memory and circadian activity.
Volume: 18
Issue: 1
Pages: 155
Publication
First Author: Paul JR
Year: 2017
Journal: Eur J Neurosci
Title: Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus.
Volume: 45
Issue: 8
Pages: 1102-1110
Publication
First Author: Deery MJ
Year: 2009
Journal: Curr Biol
Title: Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock.
Volume: 19
Issue: 23
Pages: 2031-6
Publication
First Author: Li JD
Year: 2006
Journal: J Neurosci
Title: Attenuated circadian rhythms in mice lacking the prokineticin 2 gene.
Volume: 26
Issue: 45
Pages: 11615-23
Publication
First Author: Girardet C
Year: 2013
Journal: Glia
Title: Brain-derived neurotrophic factor/TrkB signaling regulates daily astroglial plasticity in the suprachiasmatic nucleus: electron-microscopic evidence in mouse.
Volume: 61
Issue: 7
Pages: 1172-7