| Type |
Details |
Score |
| Publication |
| First Author: |
Kim AB |
| Year: |
2024 |
| Journal: |
JCI Insight |
| Title: |
Chimeric antigen receptor macrophages target and resorb amyloid plaques. |
| Volume: |
9 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen Z |
| Year: |
2024 |
| Journal: |
Cell |
| Title: |
Flexible scaffold-based cheminformatics approach for polypharmacological drug design. |
| Volume: |
187 |
| Issue: |
9 |
| Pages: |
2194-2208.e22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyr B |
| Year: |
2024 |
| Journal: |
Front Mol Neurosci |
| Title: |
Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer's disease mice. |
| Volume: |
17 |
|
| Pages: |
1369781 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Razazan A |
| Year: |
2021 |
| Journal: |
Front Aging Neurosci |
| Title: |
Activation of Microbiota Sensing - Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis. |
| Volume: |
13 |
|
| Pages: |
735933 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rechnitz O |
| Year: |
2021 |
| Journal: |
Curr Biol |
| Title: |
Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer's disease model mice. |
| Volume: |
31 |
| Issue: |
15 |
| Pages: |
3292-3302.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kashyap G |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Synapse loss and progress of Alzheimer's disease -A network model. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
6555 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng D |
| Year: |
2013 |
| Journal: |
Behav Brain Res |
| Title: |
Novel behavioural characteristics of the APP(Swe)/PS1ΔE9 transgenic mouse model of Alzheimer's disease. |
| Volume: |
245 |
|
| Pages: |
120-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cisternas P |
| Year: |
2023 |
| Journal: |
Front Endocrinol (Lausanne) |
| Title: |
Adiponectin and resistin modulate the progression of Alzheimer´s disease in a metabolic syndrome model. |
| Volume: |
14 |
|
| Pages: |
1237796 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li C |
| Year: |
2024 |
| Journal: |
Front Neurosci |
| Title: |
8-weeks aerobic exercise ameliorates cognitive deficit and mitigates ferroptosis triggered by iron overload in the prefrontal cortex of APP (Swe)/PSEN (1dE9) mice through Xc(-)/GPx4 pathway. |
| Volume: |
18 |
|
| Pages: |
1453582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yi-Bin W |
| Year: |
2022 |
| Journal: |
Cell Death Dis |
| Title: |
Inhibition of the CEBPβ-NFκB interaction by nanocarrier-packaged Carnosic acid ameliorates glia-mediated neuroinflammation and improves cognitive function in an Alzheimer's disease model. |
| Volume: |
13 |
| Issue: |
4 |
| Pages: |
318 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee D |
| Year: |
2024 |
| Journal: |
Int J Mol Sci |
| Title: |
In Vivo Evaluation of Nose-to-Brain Delivery of Liposomal Donepezil, Memantine, and BACE-1 siRNA for Alzheimer's Disease Therapy. |
| Volume: |
25 |
| Issue: |
19 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Heo JJ |
| Year: |
2025 |
| Journal: |
Phytother Res |
| Title: |
Suffruticosol B from Paeonia lactiflora Ameliorates Alzheimer's Disease Pathology by Inhibiting MAO-B Activity. |
| Volume: |
39 |
| Issue: |
2 |
| Pages: |
593-603 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Masliah E |
| Year: |
2000 |
| Journal: |
Science |
| Title: |
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. |
| Volume: |
287 |
| Issue: |
5456 |
| Pages: |
1265-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sokolov D |
| Year: |
2021 |
| Journal: |
Elife |
| Title: |
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons. |
| Volume: |
10 |
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Grenell A |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Loss of MPC1 reprograms retinal metabolism to impair visual function. |
| Volume: |
116 |
| Issue: |
9 |
| Pages: |
3530-3535 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li B |
| Year: |
2024 |
| Journal: |
Neurobiol Dis |
| Title: |
Overexpression of Bmp4 induces microphthalmia by disrupting embryonic neural retina. |
| Volume: |
201 |
|
| Pages: |
106654 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chalamalasetty RB |
| Year: |
2016 |
| Journal: |
Genesis |
| Title: |
A new gain-of-function mouse line to study the role of Wnt3a in development and disease. |
| Volume: |
54 |
| Issue: |
9 |
| Pages: |
497-502 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Murera D |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
CD4 T cell autophagy is integral to memory maintenance. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
5951 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sans MD |
| Year: |
2011 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Secretin is not necessary for exocrine pancreatic development and growth in mice. |
| Volume: |
301 |
| Issue: |
5 |
| Pages: |
G791-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reddi PP |
| Year: |
1999 |
| Journal: |
Biol Reprod |
| Title: |
Round spermatid-specific transcription of the mouse SP-10 gene is mediated by a 294-base pair proximal promoter. |
| Volume: |
61 |
| Issue: |
5 |
| Pages: |
1256-66 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Eldor R |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents. |
| Volume: |
103 |
| Issue: |
13 |
| Pages: |
5072-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song MJ |
| Year: |
2023 |
| Journal: |
Aging Cell |
| Title: |
Carnitine acetyltransferase deficiency mediates mitochondrial dysfunction-induced cellular senescence in dermal fibroblasts. |
| Volume: |
22 |
| Issue: |
11 |
| Pages: |
e14000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tetik-Elsherbiny N |
| Year: |
2024 |
| Journal: |
Nat Cardiovasc Res |
| Title: |
RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth. |
| Volume: |
3 |
| Issue: |
10 |
| Pages: |
1199-1216 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bengsch B |
| Year: |
2016 |
| Journal: |
Immunity |
| Title: |
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion. |
| Volume: |
45 |
| Issue: |
2 |
| Pages: |
358-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Odorizzi PM |
| Year: |
2015 |
| Journal: |
J Exp Med |
| Title: |
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells. |
| Volume: |
212 |
| Issue: |
7 |
| Pages: |
1125-37 |
|
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•
•
•
•
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| Publication |
| First Author: |
Syed NA |
| Year: |
1998 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Transgenic mice with pigmented intraocular tumors: tissue of origin and treatment. |
| Volume: |
39 |
| Issue: |
13 |
| Pages: |
2800-5 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Sánchez-González C |
| Year: |
2020 |
| Journal: |
EMBO J |
| Title: |
Dysfunctional oxidative phosphorylation shunts branched-chain amino acid catabolism onto lipogenesis in skeletal muscle. |
| Volume: |
39 |
| Issue: |
14 |
| Pages: |
e103812 |
|
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•
•
•
•
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| Publication |
| First Author: |
Xiong T |
| Year: |
2022 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model. |
| Volume: |
323 |
| Issue: |
2 |
| Pages: |
E145-E158 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dupressoir A |
| Year: |
1996 |
| Journal: |
Mol Cell Biol |
| Title: |
Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice. |
| Volume: |
16 |
| Issue: |
8 |
| Pages: |
4495-503 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Graber TG |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration. |
| Volume: |
294 |
| Issue: |
11 |
| Pages: |
4091-4102 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marcotte GR |
| Year: |
2023 |
| Journal: |
JCI Insight |
| Title: |
GADD45A is a mediator of mitochondrial loss, atrophy, and weakness in skeletal muscle. |
| Volume: |
8 |
| Issue: |
22 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li L |
| Year: |
2022 |
| Journal: |
Blood |
| Title: |
HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression. |
| Volume: |
139 |
| Issue: |
18 |
| Pages: |
2797-2815 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Bertocci B |
| Year: |
1998 |
| Journal: |
Immunity |
| Title: |
Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process. |
| Volume: |
9 |
| Issue: |
2 |
| Pages: |
257-65 |
|
•
•
•
•
•
|
| Allele |
| Name: |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13; hyperspin |
| Allele Type: |
Spontaneous |
| Attribute String: |
Dominant negative, Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim J |
| Year: |
2016 |
| Journal: |
Nucleic Acids Res |
| Title: |
Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability. |
| Volume: |
44 |
| Issue: |
7 |
| Pages: |
e64 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Ortega-Molina A |
| Year: |
2012 |
| Journal: |
Cell Metab |
| Title: |
Pten positively regulates brown adipose function, energy expenditure, and longevity. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
382-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gräler MH |
| Year: |
2005 |
| Journal: |
J Immunol |
| Title: |
Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes. |
| Volume: |
174 |
| Issue: |
4 |
| Pages: |
1997-2003 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lectez B |
| Year: |
2014 |
| Journal: |
J Proteome Res |
| Title: |
Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
3016-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ho AM |
| Year: |
2000 |
| Journal: |
Science |
| Title: |
Role of the mouse ank gene in control of tissue calcification and arthritis. |
| Volume: |
289 |
| Issue: |
5477 |
| Pages: |
265-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Manichaikul A |
| Year: |
2011 |
| Journal: |
Am J Physiol Heart Circ Physiol |
| Title: |
Characterization of Ath29, a major mouse atherosclerosis susceptibility locus, and identification of Rcn2 as a novel regulator of cytokine expression. |
| Volume: |
301 |
| Issue: |
3 |
| Pages: |
H1056-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paigen B |
| Year: |
1987 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in mice. |
| Volume: |
84 |
| Issue: |
11 |
| Pages: |
3763-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ishida BY |
| Year: |
1991 |
| Journal: |
J Lipid Res |
| Title: |
Effects of atherogenic diet consumption on lipoproteins in mouse strains C57BL/6 and C3H. |
| Volume: |
32 |
| Issue: |
4 |
| Pages: |
559-68 |
|
•
•
•
•
•
|
| Allele |
| Name: |
leishmaniasis resistance 17; CcS20/Dem |
| Allele Type: |
QTL |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
fat induced diabetes 1; C57BLKS/J |
| Allele Type: |
QTL |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
HDL QTL 58; C57BL/6J |
| Allele Type: |
QTL |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, spontaneous mutation |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tnfsf4/? |
| Background: |
involves: C3H/HeJ * C57BL/6J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tnfsf4/? |
| Background: |
involves: BALB/cJ * C57BL/6J |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tnfsf4/Tnfsf4 |
| Background: |
B6.PERA-Tnfsf4/Pgn |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pgis1/Pgis1 |
| Background: |
involves: BALB/c * DBA/2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pgis2/Pgis2 |
| Background: |
involves: BALB/c * DBA/2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pgis2/Pgis2 |
| Background: |
involves: BALB/c * DBA/2 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ath29/Ath29 |
| Background: |
involves: C3H/HeJ * C57BL/6J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ank/Ank Tg(282M13)1Kng/? |
| Background: |
involves: 129 * C3H/HeJ * C57BL/6J * CBA/J * FVB/N |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Apoe/Apoe Tnfsf4/Tnfsf4 |
| Background: |
involves: C3H/HeJ * C57BL/6J |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
dft/dft |
| Background: |
B6;FVB-dft/GrsrJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wallace ME |
| Year: |
1987 |
| Journal: |
Mouse News Lett |
| Title: |
Polydactyly short tail, Pst. |
| Volume: |
78 |
|
| Pages: |
40-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwahn DJ |
| Year: |
2018 |
| Journal: |
Genetics |
| Title: |
Genetic Dissection of Hybrid Male Sterility Across Stages of Spermatogenesis. |
| Volume: |
210 |
| Issue: |
4 |
| Pages: |
1453-1465 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE20902 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
Baseline |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Allele |
| Name: |
columbus; Columbus |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Allele |
| Name: |
Cortes |
| Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transgenic, congenic, chemically induced mutation |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion F2, Harry C Dietz |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang Z |
| Year: |
2010 |
| Journal: |
Life Sci |
| Title: |
The mouse forkhead gene Foxp2 modulates expression of the lung genes. |
| Volume: |
87 |
| Issue: |
1-2 |
| Pages: |
17-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiba Y |
| Year: |
2023 |
| Journal: |
FASEB J |
| Title: |
Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. |
| Volume: |
37 |
| Issue: |
4 |
| Pages: |
e22861 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nik AM |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Foxf2 is required for secondary palate development and Tgfβ signaling in palatal shelf mesenchyme. |
| Volume: |
415 |
| Issue: |
1 |
| Pages: |
14-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li G |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
High-throughput metabolomics and ingenuity pathway approach reveals the pharmacological effect and targets of Ginsenoside Rg1 in Alzheimer's disease mice. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
7040 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chu TT |
| Year: |
2016 |
| Journal: |
Cell Chem Biol |
| Title: |
Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation. |
| Volume: |
23 |
| Issue: |
4 |
| Pages: |
453-61 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1132
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kam TI |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Um JW |
| Year: |
2013 |
| Journal: |
Neuron |
| Title: |
Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. |
| Volume: |
79 |
| Issue: |
5 |
| Pages: |
887-902 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hargis KE |
| Year: |
2017 |
| Journal: |
Behav Brain Res |
| Title: |
Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us? |
| Volume: |
322 |
| Issue: |
Pt B |
| Pages: |
311-328 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun S |
| Year: |
2014 |
| Journal: |
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