|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 6201 to 6300 out of 6883 for Pax6

<< First    < Previous  |  Next >    Last >>
0.035s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
Probe: MGI:7336054
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7336061
Age: embryonic day 13.5
Image: 5A
Note: Expression predomininantly in nuclear transitory zone; not co-localized with Pax6 expression in rhombic lip and beginning of subpial stream.
Specimen Label: 5A
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7703274
Assay Type: Immunohistochemistry
Annotation Date: 2024-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7703277
Age: embryonic day 16.5
Note: Expression in radial glial cell bodies, co-localized with Pax6 expression in most cells, and in cell processes.
Specimen Label: 1B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437484
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3539028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6437506
Age: postnatal day 4
Note: Expression within dermal matrix or inner root sheath of hair follicles from body skin. No overlap with Pax6 expression.
Specimen Label: S1B/C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7461445
Age: embryonic day 11.5
Image: 2L
Note: Expressed in differentiating cells in the mantle zone of the ventral telencephalon, in regions where Pax6 had no expression.
Specimen Label: 2L
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6437484
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6437506
Age: postnatal day 4
Note: Expression within dermal matrix or inner root sheath of hair follicles from body skin. No overlap with Pax6 expression.
Specimen Label: S1B/C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6356547
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360726
Age: embryonic day 14.5
Image: 5G
Note: In the mutant, there were cells co-expressing Vsx2 and Pax6 and occasionally cells co-expressing Gata3 and Vsx2.
Specimen Label: 5G
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6360698
Age: embryonic day 13.5
Image: S1A
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1A
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6360698
Age: embryonic day 15.5
Image: S1D
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1D
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757725
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6360698
Age: embryonic day 17.5
Image: S1G
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1G
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5014292
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6360698
Age: postnatal day 4
Image: S1J
Note: The lineage relationship between Foxn4-expressing progenitors and Pax6 interneurons continued to hold true at a range of developmental stages.
Specimen Label: S1J
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358640
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358650
Age: postnatal day 0
Image: 2D
Note: The rostral domain of expression in the wild type cortex exhibits a rostral restriction in Pax6 mutants.
Specimen Label: 2D
Detected: true
Specimen Num: 4
•
•
•
•
•
Allele
Pax6<tm1Pgr> | MGI:1934347
Name: paired box 6; targeted mutation 1, Peter Gruss
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Publication
22562503 | J:196814
First Author: Wadhwa L
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Embryonic retinal tumors in SV40 T-Ag transgenic mice contain CD133+ tumor-initiating cells.
Volume: 53
Issue: 7
Pages: 3454-62
•
•
•
•
•
MP Term
MP:0021102 | abnormal ventral interneuron 0 morphology
•
•
•
•
•
Allele
Pax6<7Neu> | MGI:2156738
 
Name: paired box 6; 7, Neuherberg
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<4Neu> | MGI:2156741
 
Name: paired box 6; 4, Neuherberg
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<3Neu> | MGI:2156742
 
Name: paired box 6; 3, Neuherberg
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<1Jrt> | MGI:2680557
 
Name: paired box 6; 1, Janet Rossant
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<Rgsc242> | MGI:3799162
 
Name: paired box 6; RIKEN Genomic Sciences Center, 242
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Tg(Pax6-HRAS*G12V)2044Ove | MGI:5430364
Name: transgene insertion 2044, Paul A Overbeek
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Tg(Pax6-TAg)1796Hur | MGI:5517702
Name: transgene insertion 1796, Richard L Hurwitz
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Pax6<tm1.1Zkoz> | MGI:5567084
Name: paired box 6; targeted mutation 1.1, Zbynek Kozmik
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Pax6<em1Jkm> | MGI:6203122
 
Name: paired box 6; endonuclease-mediated mutation 1, Jin Woo Kim
Allele Type: Endonuclease-mediated
•
•
•
•
•
Allele
Pax6<em1Inot> | MGI:7282260
Name: paired box 6; endonuclease-mediated mutation 1, Takayoshi Inoue
Allele Type: Endonuclease-mediated
Attribute String: Reporter
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Pax6-HRAS*G12V)2044Ove/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358641
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358673
Age: embryonic day 18.5
Image: 3B'
Note: In Pax6 mutant, the boundary between strong and weak layer 5 expression is shifted rostrally. The domain of strong expression in layers 2/3 was absent throughout the neocortex.
Specimen Label: 3B'
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358639
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358672
Age: embryonic day 18.5
Image: 3D'
Note: In Pax6 mutants, the rostral domain is essentially absent, and high levels of expression continue to the rostral pole of the neocortex.
Specimen Label: 3D'
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358642
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358674
Age: embryonic day 18.5
Image: 4B'
Note: In Pax6 mutants, expression constricted rostrally, and there was virtually no expression detected in any layers in the caudal half of the neocortex.
Specimen Label: 4B'
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6358645
Assay Type: RNA in situ
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6358677
Age: embryonic day 18.5
Image: 5D'
Note: In Pax6 mutants a domain of lower expression was not evident, but a small domain of reduced expression was apparent and restricted to a more rostral position.
Specimen Label: 5D'
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7314968
Assay Type: RNA in situ
Annotation Date: 2022-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7314984
Age: embryonic day 13.5
Image: 2A
Note: Variable levels of let-7d expression within Pax6-expressing progenitors along apical-basal axis of Pax6 domain. Higher levels of expression in basal region compared to those located more apically.
Specimen Label: 2A
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707367
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5707612
Age: embryonic day 18.0
Note: Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.
Specimen Label: 3A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5707367
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5707612
Age: embryonic day 18.0
Note: Expression deeper in the cerebellar anlage and inner granule cell layer co-expressed Pax6. There was no co-expression with Pax6 in the rhombic lip.
Specimen Label: 3C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:2150169
Assay Type: Immunohistochemistry
Annotation Date: 2003-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:2676238
Age: embryonic day 10.5
Image: 1H,1I
Note: Expressed in gap in expression of Pax6 and Nkx2.1 expands, partially overlapping with Pax6 expression, expanded more ventrally into Nkx2.1-positive domain.
Specimen Label: 1H,1I
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689615
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7461456
Age: embryonic day 9.5
Image: 4B/C
Note: Expressed in a narrower region, extending from the floorplate to the roofplate, whose alar domain overlaps a central portion of the diencephalic domain of Pax6 expression.
Specimen Label: 4B/C
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1D
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression (summarized in Fig 1M).
Specimen Label: 1D
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1E
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression (summarized in Fig 1M).
Specimen Label: 1E
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7434439
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7434448
Age: postnatal day 0
Image: 1D
Note: Coexpressed with Pax6 in the outer most layers of the external granule cell layer, limited to 1-2 cell layers from the meninges.
Specimen Label: 1D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1331403
Assay Type: RNA in situ
Annotation Date: 2013-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5490759
Age: embryonic day 12.5
Image: 2A
Note: Expression was detected in the ventral thalamus. Expression overlapped with both Pax6 and Dlx2 at their caudal edges. Expression ended at the ventral/dorsal thalamus boundary.
Specimen Label: 2A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7524695
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524724
Age: embryonic day 12.5
Image: 7E
Note: At more caudal level, thalamocortical axon bundle does not express Lhx5. Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5. Expression in putative ventral lateral geniculate nucleus.
Specimen Label: 7E
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7524694
Assay Type: RNA in situ
Annotation Date: 2023-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7524723
Age: embryonic day 12.5
Image: 7B
Note: At more caudal level, thalamocortical axon bundle does not express Lhx1. Domain expressing Lhx1, Isl1 and Pax6 but not Lhx5. Expression in putative ventral lateral geniculate nucleus.
Specimen Label: 7B
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 5F
Note: In mutants, expression was detected in interneurons, but there was no co-expression with Pax6 interneurons. Some cells co-expressed Gata3 and Vsx2.
Specimen Label: 5F
Detected: true
Specimen Num: 4
•
•
•
•
•
HT Experiment
GSE121213 | Transcription Factors Dlx1/2 Are Required for Making All Interneurons in the Olfactory Bulb [Pax6]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
•
•
•
•
•
Allele
Evx1<tm1.1Gld> | MGI:2182858
Name: even-skipped homeobox 1; targeted mutation 1.1, Martyn Goulding
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
•
•
•
•
•
Allele
Pax6<tm2Pgr> | MGI:1934348
Name: paired box 6; targeted mutation 2, Peter Gruss
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6<1Jrt>/Pax6<+>
Background: C3.B6-Pax6<1Jrt>
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6<3Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6<4Neu>/Pax6<+>
Background: either: (involves: 102 * C3H) or (involves: C3H)
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6<7Neu>/Pax6<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
DO Term
DOID:0060673 | Peters anomaly
•
•
•
•
•
Allele
Pax6<Sey-H> | MGI:1856156
 
Name: paired box 6; small eye, Harwell
Allele Type: Radiation induced
•
•
•
•
•
Strain
MGI:3799165 | D2;B6-Pax6<Rgsc242>/Rbrc
Attribute String: chemically induced mutation, mutant stock
•
•
•
•
•
Allele
Tg(Dach1-Pax6)1Jlr | MGI:4837141
Name: transgene insertion 1, John L R Rubenstein
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Allele
Pax6<em1Smoc> | MGI:7291543
Name: paired box 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Allele
Pax6<em1(cre)Cya> | MGI:7657306
Name: paired box 6; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6<+>
Background: involves: C57BL/6JJcl * DBA/2JJcl
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Pax6-TAg)1796Hur/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Proximal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Proximal Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Middle Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Middle Control
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6293890
Assay Type: RNA in situ
Annotation Date: 2019-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6293896
Age: embryonic day 13.5
Image: 1C Distal Control
Note: There was a spatial dose-dependent inverse relationship between Pax6 and Sox9, with a significant negative correlation between the mRNA levels. A central to peripheral gradient was noted for Sox9 transcripts.
Specimen Label: 1C Distal Control
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7286347
Assay Type: RNA in situ
Annotation Date: 2022-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7286370
Age: embryonic day 14.5
Image: 2D/D'
Note: Expression was abnormal in the cortex and showed no obvious decrease on the pallial side of the pallial-subpallial boundary. Expression in subpallium continued across the boundary deep into the lateral cortex where they now overlapped high Pax6 expression.
Specimen Label: 2D/D'
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5287686
Assay Type: RNA in situ
Annotation Date: 2023-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:7461445
Age: embryonic day 8.5
Image: 1F
Note: Expressed throughout much of the diencephalon, with strongest expression in alar regions overlapping the middle of the diencephalic domain of Pax6 expression. No expression in the telencephalon (summarized in Fig 1M).
Specimen Label: 1F
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 3D
Note: Expression was detected in V2b interneurons. There was some co-expression with Pax6 positive interneurons settled in the ventral spinal cord and not when they migrated out of the ventricular zone.
Specimen Label: 3D
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6360651
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6360727
Age: embryonic day 14.5
Image: 4B
Note: Expression was detected in V2b interneurons. There was some co-expression with Pax6 positive interneurons settled in the ventral spinal cord and not when they migrated out of the ventricular zone.
Specimen Label: 4B
Detected: true
Specimen Num: 2
•
•
•
•
•
Genotype
Genotype
Symbol: Evx1/Evx1
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
12324464 | -
First Author: Tominaga T
Year: 2002
Journal: J Biol Chem
Title: The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6.
Volume: 277
Issue: 49
Pages: 47686-91
•
•
•
•
•
Strain
MGI:5650102 | (C57BL/10-Pax6<Sey-H>/+ x M. spretus)F1
Attribute String: F1 hybrid, mutant stock
•
•
•
•
•
Strain
MGI:2160689 | C57BL/10Nimr-+/Pax6<Sey-H>
Attribute String: mutant strain
•
•
•
•
•
Strain
MGI:3579045 | C3H101H-Pax6<Sey-H>/H
Attribute String: radiation induced mutation, mutant stock
•
•
•
•
•
Strain
MGI:5650528 | (C57BL/10-Pax6<Sey-H> x M. spretus)F1
Attribute String: F1 hybrid, mutant stock
•
•
•
•
•
Strain
MGI:5650173 | (C57BL/10Nimr +/Pax6<Sey-H> x M. spretus)F1
Attribute String: F1 hybrid, mutant stock
•
•
•
•
•
Strain
MGI:2160938 | C57BL/6-Pax6<Sey-H>
Attribute String: mutant strain
•
•
•
•
•
Allele
Tg(Pax6-cre)1Rilm | MGI:2450279
Name: transgene insertion 1, Richard L Maas
Allele Type: Transgenic
Attribute String: Recombinase
•
•
•
•
•
Allele
Tg(Pax6-cre)1Knd | MGI:3624748
Name: transgene insertion 1, Hisato Kondoh
Allele Type: Transgenic
Attribute String: Recombinase
•
•
•
•
•
Strain
MGI:5576219 | B6.Cg-Tg(Dach1-Pax6)1Jlr/Mmucd
Attribute String: congenic, mutant strain, transgenic
•
•
•
•
•
Strain
MGI:7657567 | C57BL/6J-Pax6<em1(cre)Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6
Background: involves: 101/H * C3H/HeH
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6<+>
Background: involves: 101/H * C3H/HeH
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Publication
20735985 | J:165593
First Author: Liu Y
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Inactivation of Smad4 leads to impaired ocular development and cataract formation.
Volume: 400
Issue: 4
Pages: 476-82
•
•
•
•
•
Publication
19632219 | J:153549
First Author: Chen Y
Year: 2009
Journal: Dev Biol
Title: Conditional deletion of Cited2 results in defective corneal epithelial morphogenesis and maintenance.
Volume: 334
Issue: 1
Pages: 243-52
•
•
•
•
•
Genotype
Genotype
Symbol: Dbx1/Dbx1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Gene
1545 | CYP1B1
Type: gene
Organism: human
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7621468
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7621559
Age: embryonic day 12.5
Image: 6C ESCO2cKO
Note: In the conditional mutant, expression was lower in the lateral area of the cortex. Co-expression with Casp3 and Pax6 indicated that increased apoptosis was mainly in intermediate progenitor cells (Eomes+) and and cells in transition stage between radial glia progenitor cells/intermediate progenitor cells (Eomes+/Pax6+).
Specimen Label: 6C ESCO2cKO
Detected: true
Specimen Num: 6
•
•
•
•
•
Strain
MGI:4835051 | STOCK Pax6<tm1Pgr>/Cnrm
Attribute String: mutant stock, targeted mutation
•
•
•
•
•
Strain
MGI:5649345 | B6N.129(Cg)-Pax6<tm1Pgr>/J
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Allele
Pax6<Leca4> | MGI:1934618
 
Name: paired box 6; lens corneal adhesion 4
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<Leca2> | MGI:1934621
 
Name: paired box 6; lens corneal adhesion 2
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<Leca1> | MGI:1934622
 
Name: paired box 6; lens corneal adhesion 1
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Pax6<Leca3> | MGI:1934632
 
Name: paired box 6; lens corneal adhesion 3
Allele Type: Chemically induced (ENU)
•
•
•
•
•
Allele
Tg(Pax6-cre,GFP)1Pgr | MGI:3045749
Name: transgene insertion 1, Peter Gruss
Allele Type: Transgenic
Attribute String: Recombinase
•
•
•
•
•
Allele
Del(2)Pax6<13Neu> | MGI:3845753
 
Name: deletion, Chr 2, Neuherberg 13
Allele Type: Spontaneous
•
•
•
•
•
Allele
Del(2)Pax6<12Neu> | MGI:3845767
 
Name: deletion, Chr 2, Neuherberg 12
Allele Type: Radiation induced
•
•
•
•
•
Allele
Pax6<tm2(Pax6_i5a,Pax2)Xzh> | MGI:5512910
Name: paired box 6; targeted mutation 2, Xin Zhang
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6
Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Pax6/Pax6 Tg(KRT14-cre)#Smr/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom