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Search results 6201 to 6300 out of 7671 for Th

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Hits by Strain

Type Details Score
Genotype
Symbol: Tgfb1/Tgfb1 Tg(Cd4-cre)1Cwi/?
Background: involves: 129 * C57BL/6 * DBA/2 * NOD
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Th/Th<+>
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Th/Th<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Baasanjav S
Year: 2011
Journal: Am J Hum Genet
Title: Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Volume: 89
Issue: 1
Pages: 15-27
Publication
First Author: Horikawa Y
Year: 2000
Journal: Nat Genet
Title: Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Volume: 26
Issue: 2
Pages: 163-75
Publication
First Author: Suh WK
Year: 2003
Journal: Nat Immunol
Title: The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses.
Volume: 4
Issue: 9
Pages: 899-906
Publication
First Author: Miraoui H
Year: 2013
Journal: Am J Hum Genet
Title: Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.
Volume: 92
Issue: 5
Pages: 725-43
Publication
First Author: Nogusa S
Year: 2016
Journal: Cell Host Microbe
Title: RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Volume: 20
Issue: 1
Pages: 13-24
Publication
First Author: Heissenberger C
Year: 2019
Journal: Nucleic Acids Res
Title: Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth.
Volume: 47
Issue: 22
Pages: 11807-11825
Publication
First Author: Drummond RA
Year: 2015
Journal: PLoS Pathog
Title: CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.
Volume: 11
Issue: 12
Pages: e1005293
Publication
First Author: Froese DS
Year: 2013
Journal: Structure
Title: Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.
Volume: 21
Issue: 7
Pages: 1182-92
Publication
First Author: Min BJ
Year: 2011
Journal: Am J Hum Genet
Title: Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type.
Volume: 89
Issue: 6
Pages: 760-6
Publication
First Author: Guzman J
Year: 2014
Journal: Diabetes
Title: Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Volume: 63
Issue: 2
Pages: 701-14
Publication
First Author: Mitrofanova A
Year: 2019
Journal: Nat Commun
Title: SMPDL3b modulates insulin receptor signaling in diabetic kidney disease.
Volume: 10
Issue: 1
Pages: 2692
Publication
First Author: Hung CN
Year: 2023
Journal: Cell Rep
Title: AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages.
Volume: 42
Issue: 9
Pages: 113067
Publication
First Author: Bentsen MA
Year: 2020
Journal: Nat Commun
Title: Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.
Volume: 11
Issue: 1
Pages: 4458
Publication
First Author: Sancar G
Year: 2022
Journal: Cell Metab
Title: FGF1 and insulin control lipolysis by convergent pathways.
Volume: 34
Issue: 1
Pages: 171-183.e6
Publication
First Author: Baazim H
Year: 2019
Journal: Nat Immunol
Title: CD8+ T cells induce cachexia during chronic viral infection.
Volume: 20
Issue: 6
Pages: 701-710
Publication
First Author: Suh JM
Year: 2014
Journal: Nature
Title: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.
Volume: 513
Issue: 7518
Pages: 436-9
Publication
First Author: Han JX
Year: 2023
Journal: Nat Microbiol
Title: Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer.
Volume: 8
Issue: 5
Pages: 919-933
Publication
First Author: Ringel AE
Year: 2020
Journal: Cell
Title: Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.
Volume: 183
Issue: 7
Pages: 1848-1866.e26
Publication
First Author: Wei S
Year: 2015
Journal: Nat Med
Title: Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.
Volume: 21
Issue: 5
Pages: 457-66
Publication
First Author: Jiang Z
Year: 2023
Journal: Cell Stem Cell
Title: Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis.
Volume: 30
Issue: 8
Pages: 1091-1109.e7
Publication
First Author: Hsieh MH
Year: 2019
Journal: Cell Rep
Title: p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas.
Volume: 28
Issue: 7
Pages: 1860-1878.e9
Publication
First Author: Koikawa K
Year: 2021
Journal: Cell
Title: Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.
Volume: 184
Issue: 18
Pages: 4753-4771.e27
Publication
First Author: Pichler AC
Year: 2023
Journal: Immunity
Title: TCR-independent CD137 (4-1BB) signaling promotes CD8(+)-exhausted T cell proliferation and terminal differentiation.
Volume: 56
Issue: 7
Pages: 1631-1648.e10
Publication
First Author: Song JJ
Year: 2011
Journal: J Clin Invest
Title: Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis.
Volume: 121
Issue: 9
Pages: 3517-27
Publication
First Author: Chen D
Year: 2023
Journal: Immunity
Title: CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Volume: 56
Issue: 9
Pages: 2086-2104.e8
Publication
First Author: Chan CC
Year: 2021
Journal: Nat Commun
Title: A BAFF/APRIL axis regulates obesogenic diet-driven weight gain.
Volume: 12
Issue: 1
Pages: 2911
Publication
First Author: Hall AO
Year: 2012
Journal: Immunity
Title: The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.
Volume: 37
Issue: 3
Pages: 511-23
Publication
First Author: Sun X
Year: 2017
Journal: Cancer Cell
Title: Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Volume: 32
Issue: 5
Pages: 574-589.e6
Publication
First Author: Lu SX
Year: 2010
Journal: J Immunol
Title: Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
Volume: 185
Issue: 3
Pages: 1912-9
Publication
First Author: Guerrina N
Year: 2021
Journal: FASEB J
Title: Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms.
Volume: 35
Issue: 3
Pages: e21376
Publication
First Author: Jordan S
Year: 2019
Journal: Cell
Title: Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.
Volume: 178
Issue: 5
Pages: 1102-1114.e17
Publication
First Author: Kuo HP
Year: 2010
Journal: Sci Signal
Title: ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Volume: 3
Issue: 108
Pages: ra9
Publication
First Author: Li Q
Year: 2022
Journal: Cell Death Differ
Title: Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development.
Volume: 29
Issue: 8
Pages: 1596-1610
Publication
First Author: Greenwood HE
Year: 2024
Journal: Nat Commun
Title: Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography.
Volume: 15
Issue: 1
Pages: 10484
Publication    
First Author: Maculins T
Year: 2021
Journal: Elife
Title: Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response.
Volume: 10
Publication
First Author: Langer V
Year: 2019
Journal: J Clin Invest
Title: IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption.
Volume: 129
Issue: 11
Pages: 4691-4707
Publication
First Author: Paragas N
Year: 2014
Journal: J Clin Invest
Title: α-Intercalated cells defend the urinary system from bacterial infection.
Volume: 124
Issue: 7
Pages: 2963-76
Publication
First Author: Polusani SR
Year: 2019
Journal: Cancer Res
Title: Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer.
Volume: 79
Issue: 1
Pages: 196-208
Publication
First Author: Marino C
Year: 2024
Journal: Alzheimers Dement
Title: APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Volume: 20
Issue: 2
Pages: 819-836
Publication
First Author: Su X
Year: 2012
Journal: J Clin Invest
Title: The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
Volume: 122
Issue: 10
Pages: 3579-92
Publication
First Author: Liu P
Year: 2014
Journal: Nature
Title: Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Volume: 508
Issue: 7497
Pages: 541-5
Publication
First Author: Sheikh BN
Year: 2020
Journal: Nat Cell Biol
Title: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature.
Volume: 22
Issue: 7
Pages: 828-841
Publication
First Author: Louveau A
Year: 2018
Journal: Nat Neurosci
Title: CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.
Volume: 21
Issue: 10
Pages: 1380-1391
Publication  
First Author: Wijers M
Year: 2019
Journal: JCI Insight
Title: The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.
Volume: 4
Issue: 11
Publication
First Author: Deguise MO
Year: 2019
Journal: Ann Clin Transl Neurol
Title: Abnormal fatty acid metabolism is a core component of spinal muscular atrophy.
Volume: 6
Issue: 8
Pages: 1519-1532
Publication  
First Author: Zhou H
Year: 2022
Journal: J Clin Invest
Title: Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect.
Volume: 132
Issue: 21
Publication  
First Author: Walter LM
Year: 2018
Journal: EBioMedicine
Title: Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.
Volume: 31
Pages: 226-242
Publication
First Author: Wishart TM
Year: 2014
Journal: J Clin Invest
Title: Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy.
Volume: 124
Issue: 4
Pages: 1821-34
Publication
First Author: Prueitt RL
Year: 2016
Journal: Cancer Res
Title: An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers.
Volume: 76
Issue: 5
Pages: 1055-1065
Publication
First Author: Soriano-Baguet L
Year: 2023
Journal: Cell Rep
Title: Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions.
Volume: 42
Issue: 3
Pages: 112153
Publication
First Author: Gorski PA
Year: 2019
Journal: Circ Res
Title: Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.
Volume: 124
Issue: 9
Pages: e63-e80
Publication
First Author: Wang C
Year: 2012
Journal: J Exp Med
Title: Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
Volume: 209
Issue: 1
Pages: 77-91
Publication
First Author: Jia Y
Year: 2016
Journal: Nature
Title: Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
Volume: 534
Issue: 7605
Pages: 129-32
Publication
First Author: Moreno-Fernandez ME
Year: 2021
Journal: Cell Metab
Title: PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease.
Volume: 33
Issue: 6
Pages: 1187-1204.e9
Publication
First Author: Feng X
Year: 2023
Journal: Dev Cell
Title: Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling.
Volume: 58
Issue: 12
Pages: 1052-1070.e10
Publication
First Author: Jiang M
Year: 2011
Journal: Nat Med
Title: Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
Volume: 18
Issue: 1
Pages: 153-8
Publication
First Author: Nakamura A
Year: 2021
Journal: Sci Transl Med
Title: Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease.
Volume: 13
Issue: 616
Pages: eabg1210
Publication
First Author: Leimkühler NB
Year: 2021
Journal: Cell Stem Cell
Title: Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Volume: 28
Issue: 4
Pages: 637-652.e8
Publication
First Author: Chu C
Year: 2019
Journal: Nature
Title: The microbiota regulate neuronal function and fear extinction learning.
Volume: 574
Issue: 7779
Pages: 543-548
Publication
First Author: Chen SS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.
Volume: 106
Issue: 32
Pages: 13433-8
Publication
First Author: Kathe C
Year: 2022
Journal: Nature
Title: The neurons that restore walking after paralysis.
Volume: 611
Issue: 7936
Pages: 540-547
Publication
First Author: Mi S
Year: 2007
Journal: Nat Med
Title: LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.
Volume: 13
Issue: 10
Pages: 1228-33
Publication
First Author: Palmisano I
Year: 2019
Journal: Nat Neurosci
Title: Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons.
Volume: 22
Issue: 11
Pages: 1913-1924
Publication
First Author: Yokota T
Year: 2020
Journal: Cell
Title: Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.
Volume: 182
Issue: 3
Pages: 545-562.e23
Publication
First Author: Low AYT
Year: 2021
Journal: Nature
Title: Reverse-translational identification of a cerebellar satiation network.
Volume: 600
Issue: 7888
Pages: 269-273
Publication
First Author: Grubman A
Year: 2021
Journal: Nat Commun
Title: Transcriptional signature in microglia associated with Aβ plaque phagocytosis.
Volume: 12
Issue: 1
Pages: 3015
Publication
First Author: Kim HK
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling.
Volume: 1865
Issue: 11
Pages: 165524
Publication
First Author: Chang CS
Year: 2021
Journal: Cell Rep
Title: Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice.
Volume: 37
Issue: 8
Pages: 110016
Publication
First Author: Lee DS
Year: 2023
Journal: Diabetologia
Title: Tcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice.
Volume: 66
Issue: 5
Pages: 931-954
Publication  
First Author: Lim SH
Year: 2020
Journal: J Cell Sci
Title: Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis.
Volume: 133
Issue: 20
Publication  
First Author: La Montanara P
Year: 2020
Journal: Sci Transl Med
Title: Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models.
Volume: 12
Issue: 551
Publication  
First Author: Dickel DE
Year: 2016
Journal: Nat Commun
Title: Genome-wide compendium and functional assessment of in vivo heart enhancers.
Volume: 7
Pages: 12923
Publication
First Author: Dickel DE
Year: 2018
Journal: Cell
Title: Ultraconserved Enhancers Are Required for Normal Development.
Volume: 172
Issue: 3
Pages: 491-499.e15
Publication  
First Author: Feng SK
Year: 2021
Journal: Mol Cell Endocrinol
Title: Deficiency of Omentin-1 leads to delayed fracture healing through excessive inflammation and reduced CD31(hi)Emcn(hi) vessels.
Volume: 534
Pages: 111373
Publication
First Author: Barreira da Silva R
Year: 2022
Journal: Nat Immunol
Title: Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.
Volume: 23
Issue: 4
Pages: 568-580
Publication      
First Author: Ng JQ
Year: 2023
Journal: bioRxiv
Title: Loss of Grem1 -articular cartilage progenitor cells causes osteoarthritis.
Publication
First Author: Kvon EZ
Year: 2020
Journal: Cell
Title: Comprehensive In Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants.
Volume: 180
Issue: 6
Pages: 1262-1271.e15
Publication
First Author: Qiu H
Year: 2018
Journal: Nat Methods
Title: A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships.
Volume: 15
Issue: 11
Pages: 889-899
Publication
First Author: Dai Y
Year: 2024
Journal: Nature
Title: TMEFF1 is a neuron-specific restriction factor for herpes simplex virus.
Volume: 632
Issue: 8024
Pages: 383-389
Publication
First Author: Liu P
Year: 2013
Journal: Nat Cell Biol
Title: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Volume: 15
Issue: 11
Pages: 1340-50
Publication
First Author: Padua RA
Year: 2003
Journal: Nat Med
Title: PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.
Volume: 9
Issue: 11
Pages: 1413-7
Publication
First Author: Kimura A
Year: 1997
Journal: Nat Genet
Title: Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy.
Volume: 16
Issue: 4
Pages: 379-82
Publication
First Author: Greulich H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Volume: 109
Issue: 36
Pages: 14476-81
Publication
First Author: Kim DK
Year: 2014
Journal: Nat Med
Title: Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis.
Volume: 20
Issue: 4
Pages: 419-24
Publication
First Author: Yin J
Year: 2015
Journal: PLoS Biol
Title: Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells.
Volume: 13
Issue: 5
Pages: e1002152
Publication
First Author: Kim MY
Year: 2018
Journal: Cell
Title: Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.
Volume: 173
Issue: 6
Pages: 1439-1453.e19
Publication
First Author: Ko HG
Year: 2018
Journal: Cell Rep
Title: Rapid Turnover of Cortical NCAM1 Regulates Synaptic Reorganization after Peripheral Nerve Injury.
Volume: 22
Issue: 3
Pages: 748-759
Publication
First Author: Kumar R
Year: 2018
Journal: Nat Commun
Title: Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.
Volume: 9
Issue: 1
Pages: 3931
Publication
First Author: Melum E
Year: 2019
Journal: Nat Immunol
Title: Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Volume: 20
Issue: 12
Pages: 1644-1655
Publication
First Author: Zhou Z
Year: 2020
Journal: Science
Title: Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes.
Volume: 368
Issue: 6486
Pages: 54-60
Publication
First Author: Elrod J
Year: 2023
Journal: iScience
Title: Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions.
Volume: 26
Issue: 12
Pages: 108289
Publication
First Author: Liu H
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: JMJD5 couples with CDK9 to release the paused RNA polymerase II.
Volume: 117
Issue: 33
Pages: 19888-19895
Publication
First Author: Silva LM
Year: 2021
Journal: Science
Title: Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier.
Volume: 374
Issue: 6575
Pages: eabl5450
Publication
First Author: Lou MM
Year: 2021
Journal: Nat Commun
Title: Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons.
Volume: 12
Issue: 1
Pages: 4075
Publication
First Author: Schneider KM
Year: 2022
Journal: Nat Commun
Title: Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment.
Volume: 13
Issue: 1
Pages: 3964
Publication
First Author: Krishnamurty AT
Year: 2022
Journal: Nature
Title: LRRC15(+) myofibroblasts dictate the stromal setpoint to suppress tumour immunity.
Volume: 611
Issue: 7934
Pages: 148-154
Publication
First Author: Gjuka D
Year: 2023
Journal: Cancer Cell
Title: Enzyme-mediated depletion of methylthioadenosine restores T cell function in MTAP-deficient tumors and reverses immunotherapy resistance.
Volume: 41
Issue: 10
Pages: 1774-1787.e9