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Search results 6301 to 6400 out of 8285 for C2

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0.022s

Categories

Hits by Pathway

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Hits by Strain

Type Details Score
Protein
P01627
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: false
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Protein
A0A075B5Y0
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
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Protein
A0A075B5Q9
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
A0A075B5K3
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
J3QK03
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
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Protein
A0A0G2JDU3
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein
A0A075B693
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: false
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Protein
A0A0B4J1H9
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A140T8P7
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A075B5Q6
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
A0A075B5W4
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
A0A0A6YW58
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A0B4J1H8
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A140T8M9
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A075B5T2
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
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Protein
A0A0A6YWG4
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5X1
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
A0A075B5N0
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
A0A0B4J1I1
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
A0A075B5S4
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: false
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Protein
A0A140T8P3
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
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Protein
A0A075B5X8
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
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Protein
A0A0A6YWU3
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A075B5S6
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
A0A075B5T3
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A075B5T1
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A140T8M8
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A075B5J6
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
A0A075B5Q2
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5K8
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
A0A0B4J1H6
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A0B4J1H7
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A075B5T0
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
A0A0B4J1I0
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A0G2JE99
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
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Protein
A0A087WPN7
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
A0A075B5R0
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
A0A075B5R3
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Protein
A0A075B5S5
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: false
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Protein
J3QNN6
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
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Protein
A0A075B5R2
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A075B5R1
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A140T8M0
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A0A6YXF1
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5M9
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: false
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Protein
A0A075B5Q0
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5X4
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A075B5P9
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5P7
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
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Protein
A0A0A6YXQ0
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A075B5S0
Organism: Mus musculus/domesticus
Length: 99  
Fragment?: false
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Protein
A0A075B5Q4
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
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Protein
A0A075B5K6
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
A0A0A6YY60
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A140T8N1
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Publication
11087841 | J:66416
First Author: Vyas P
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Inositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1.
Volume: 97
Issue: 25
Pages: 13696-701
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Publication
20463662 | J:161963
First Author: Sasaki J
Year: 2010
Journal: Nature
Title: The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death.
Volume: 465
Issue: 7297
Pages: 497-501
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Publication
21496647 | J:229369
First Author: Cao P
Year: 2011
Journal: Cell
Title: Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10.
Volume: 145
Issue: 2
Pages: 300-11
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Publication
12049610 | -
First Author: Fukuda M
Year: 2002
Journal: Biochem J
Title: The C2A domain of synaptotagmin-like protein 3 (Slp3) is an atypical calcium-dependent phospholipid-binding machine: comparison with the C2A domain of synaptotagmin I.
Volume: 366
Issue: Pt 2
Pages: 681-7
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Protein
A0A0A6YXS5
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
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Protein
E9Q7X1
Organism: Mus musculus/domesticus
Length: 65  
Fragment?: false
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Protein
B7ZMQ9
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
F6R4N2
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: false
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Protein
A0A0R4J0Q2
Organism: Mus musculus/domesticus
Length: 679  
Fragment?: false
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Protein
M1JB80
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: true
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Protein
Q0VBQ7
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: false
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Protein
E9Q2C4
Organism: Mus musculus/domesticus
Length: 633  
Fragment?: true
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Protein
F8WJC1
Organism: Mus musculus/domesticus
Length: 809  
Fragment?: false
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Protein
E9QAD0
Organism: Mus musculus/domesticus
Length: 690  
Fragment?: false
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Publication
10330468 | -
First Author: Millar AA
Year: 1999
Journal: Plant Cell
Title: CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.
Volume: 11
Issue: 5
Pages: 825-38
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Publication
18465198 | -
First Author: Joubès J
Year: 2008
Journal: Plant Mol Biol
Title: The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling.
Volume: 67
Issue: 5
Pages: 547-66
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Publication
23585652 | -
First Author: Kim J
Year: 2013
Journal: Plant Physiol
Title: Arabidopsis 3-ketoacyl-coenzyme a synthase9 is involved in the synthesis of tetracosanoic acids as precursors of cuticular waxes, suberins, sphingolipids, and phospholipids.
Volume: 162
Issue: 2
Pages: 567-80
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Publication
16166264 | -
First Author: Lepore BW
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The x-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale.
Volume: 102
Issue: 39
Pages: 13819-24
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Publication
17877635 | -
First Author: Smith R
Year: 2007
Journal: J Neurochem
Title: Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.
Volume: 103
Issue: 1
Pages: 115-23
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Publication
15207266 | -
First Author: Dalfó E
Year: 2004
Journal: Neurobiol Dis
Title: Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.
Volume: 16
Issue: 1
Pages: 92-7
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Publication
24200817 | -
 
First Author: Tan MG
Year: 2014
Journal: Neurochem Int
Title: Decreased rabphilin 3A immunoreactivity in Alzheimer's disease is associated with Aβ burden.
Volume: 64
Pages: 29-36
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Publication
22308290 | -
First Author: Kurowska M
Year: 2012
Journal: Blood
Title: Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex.
Volume: 119
Issue: 17
Pages: 3879-89
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Publication
20421508 | -
First Author: Welander PV
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Identification of a methylase required for 2-methylhopanoid production and implications for the interpretation of sedimentary hopanes.
Volume: 107
Issue: 19
Pages: 8537-42
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Publication
16169853 | -
First Author: Kerr FK
Year: 2005
Journal: J Biol Chem
Title: Elucidation of the substrate specificity of the C1s protease of the classical complement pathway.
Volume: 280
Issue: 47
Pages: 39510-4
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Publication
8271968 | -
 
First Author: Arlaud GJ
Year: 1993
Journal: Methods Enzymol
Title: Human complement serine proteases C1r and C1s and their proenzymes.
Volume: 223
Pages: 61-82
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Publication
25883023 | J:227240
First Author: Kofuji S
Year: 2015
Journal: Cancer Discov
Title: INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor.
Volume: 5
Issue: 7
Pages: 730-9
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Publication
21925199 | -
First Author: Rynkiewicz NK
Year: 2012
Journal: Adv Biol Regul
Title: INPP4A/INPP4B and P-Rex proteins: related but different?
Volume: 52
Issue: 1
Pages: 265-79
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Protein Domain
IPR028698 | RPH3A
Type: Family
Description: In humans, Rabphilin-3A (RPH3A) contains two C2 domains and one RabBD (Rab-binding) domain. RPH3A may interact with the SNARE complex and regulate synaptic vesicle exocytosis and Ca2+-triggered neurotransmitter release []. It has been linked to neurodegenerative diseases, such as Huntington's disease [], Lewy body disease []and Alzheimer's disease [].
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Protein Domain
IPR028702 | Slp5
Type: Family
Description: Synaptotagmin-like protein 5 (SYTL5, also known as Slp5) belongs to the synaptotagmin-like protein family, which contains a N-terminal RabBD (Rab-binding) domain and two C-terminal C2 domains. Slp5 interacts with the GTP-bound form of Rab27A both in vitro and in intact cells. It is highly expressed in human placenta and liver. It may be involved in Rab27A-dependent membrane trafficking in specific tissues [].
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Protein Domain
IPR028704 | SYTL3
Type: Family
Description: Synaptotagmin-like protein 3 (SYTL3, also known as Slp3) belongs to the synaptotagmin-like protein family, which contains a N-terminal RabBD (Rab-binding) domain and two C-terminal C2 domains. Slp3 binds phospholipids in the presence of calcium ions []. In mouse cytotoxic T lymphocytes, Slp3 is an effector of Rab27a and interacts with kinesin-1 through the tetratricopeptide repeat of the kinesin-1 light chain [].
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Protein Domain
IPR028677 | SYT10
Type: Family
Description: Synaptotagmin-10 (SYT10) belongs to the synaptotagmin family, which is a group of membrane-trafficking proteins that contain two C-terminal C2 domains. Most of the synaptotagmins have a unique N-terminal domain that is involved in membrane anchoring or specific ligand binding. SYT10 localises to olfactory bulb and controls the Ca(2+)-dependent exocytosis that is spatially and temporally distinct from Ca(2+)-dependent synaptic vesicle exocytosis controlled by SYT1 [].
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Protein Domain
IPR035708 | Complement_C1s_subcomponent
Type: Family
Description: This entry includes the serine endopeptidase complement C1s subcomponent (MEROPS identifier S01.193). C1s has trypsin-like specificity and activates the precursors of complement components C2 and C4 [, ]. It is inhibited by C1 inhibitor []. C1s is calcium-dependent and in the golden hamster is known as calcium-dependent serine proteinase.
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Protein Domain
IPR012392 | 3-ktacl-CoA_syn
Type: Family
Description: This group represents 3-ketoacyl-CoA synthases (KCSs) from plants [, ]. They are also known as very long-chain fatty acid (VLCFA) condensing enzymes, and they catalyse the first committed step during the fatty acid elongation process, which is the condensation of C2 units to acyl-CoA. Arabidopsis contains 21 KCS members [].
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Protein Domain
IPR012561 | Ferlin_B-domain
Type: Domain
Description: The ferlin gene family are characterised by multiple tandem C2 domains and a C-terminal transmembrane domain. They are found in a wide range of species and their function remains unknown, however, mutations in its two most well-characterised members, dysferlin and otoferlin, have been implicated in human disease [].This is central domain B in proteins of the Ferlin family [].
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Protein Domain
IPR012560 | Ferlin_A-domain
Type: Domain
Description: The ferlin gene family are characterised by multiple tandem C2 domains and a C-terminal transmembrane domain. They are found in a wide range of species and their function remains unknown, however, mutations in its two most well-characterised members, dysferlin and otoferlin, have been implicated in human disease [].This is central domain A in proteins of the Ferlin family [].
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Protein Domain
IPR034530 | HpnP-like
Type: Family
Description: The enzyme in this family is involved in the C2 methylation of bacterial hopanoids. Although the reaction is shown with methylcobalamin acting as the methyl donor, it is possible that SAM might be the methyl donor for the reaction (because this is another function of the SAM cofactor) [].
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Protein Domain
IPR032376 | DOCK_N
Type: Domain
Description: This domain is found near to the N terminus of some dedicator of cytokinesis (DOCK) proteins, between the variant SH3 domain and the C2 domain []. This is an α-helical region that mediates interactions with ELMO subunits and provides a major site for interactions between the SH3 and ARM domains of these proteins [].
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Protein Domain
IPR019257 | MeTrfase_dom
Type: Domain
Description: The mycobacterial members of this family are expressed from part of the ergothioneine biosynthetic gene cluster. EGTD is the histidine methyltransferase that transfers three methyl groups to the alpha-amino moiety of histidine, in the first stage of the production of this histidine betaine derivative that carries a thiol group attached to the C2 atom of an imidazole ring [].
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Protein Domain
IPR039034 | INPP4
Type: Family
Description: This entry includes INPP4A and INPP4B. They are inositol lipid 4-phosphatases that hydrolyze PtdIns(3,4)P2, a phosphoinositide generated by PI3K signaling [, ]. They contain a C2 domain in their N termini and a phosphatase domain at their C termini. INPP4A is a suppressor of glutamate excitotoxicity in the central nervous system [], while INPP4B acts as a tumour suppressor [].
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Protein Domain
IPR040570 | LAL_C2
Type: Domain
Description: L-amino-acid ligases are ATP-grasp superfamily enzymes that catalyze the formation of an alpha-peptide bond between two l-amino acids in an ATP-dependent manner. They share a common structural architecture that consists of three domains referred to as the A-domain, B-domain and C-domain. The C domain can be further divided into the C1-subdomain and the C2-subdomain []. This entry represents the C2 subdomain.
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Protein Domain
IPR025895 | LAM_C_dom
Type: Domain
Description: This domain is found in the C-terminal of lysine-2,3-aminomutase (LAM) and is involved in dimerisation []. LAM catalyses the interconversion of L-alpha-lysine and L-beta-lysine, which proceeds by migration of the amino group from C2 to C3 concomitant with cross-migration of the 3-pro-R hydrogen of L-alpha-lysine to the 2-pro-R position of L-beta-lysine.
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Publication
16367962 | -
First Author: Yang S
Year: 2006
Journal: Plant J
Title: The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis.
Volume: 45
Issue: 2
Pages: 166-79
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Publication
11544183 | -
First Author: Hua J
Year: 2001
Journal: Genes Dev
Title: Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes.
Volume: 15
Issue: 17
Pages: 2263-72
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Protein Coding Gene
MGI:1914221 | Cdk5rap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
11472062 | J:70256
First Author: Martin N
Year: 2001
Journal: Genomics
Title: Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.
Volume: 75
Issue: 1-3
Pages: 9-16
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom