| Type |
Details |
Score |
| Genotype |
| Symbol: |
Tfap2a/Tfap2a Tg(Pax6-cre,GFP)1Pgr/? |
| Background: |
involves: 129S1/Sv * Black Swiss * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Crebbp/Crebbp Ep300/Ep300 Tg(Pax6-cre,GFP)1Pgr/? |
| Background: |
involves: 129P2/OlaHsd * FVB |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ezh2/Ezh2 Tg(Pax6-cre,GFP)2Pgr/? |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Msx2/Msx2 Tg(Pax6-cre,GFP)1Pgr/? |
| Background: |
involves: 129S2/SvPas * FVB |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pik3ca/Pik3ca Pik3cb/Pik3cb Tg(Pax6-cre,GFP)1Pgr/? |
| Background: |
involves: 129 * 129S/SvEv * FVB |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pik3ca/Pik3ca Pik3cb/Pik3cb Tg(Pax6-cre,GFP)1Pgr/? |
| Background: |
involves: 129 * 129S/SvEv * 129S7/SvEvBrd * FVB |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Fosb/Fosb Tg(Cryaa-cre)10Mlr/? |
| Background: |
involves: C57BL/6 |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki R |
| Year: |
2000 |
| Journal: |
Mech Dev |
| Title: |
Identification of RALDH-3, a novel retinaldehyde dehydrogenase, expressed in the ventral region of the retina. |
| Volume: |
98 |
| Issue: |
1-2 |
| Pages: |
37-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ormestad M |
| Year: |
2002 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Foxe3 haploinsufficiency in mice: a model for Peters' anomaly. |
| Volume: |
43 |
| Issue: |
5 |
| Pages: |
1350-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kozmik Z |
| Year: |
1999 |
| Journal: |
Dev Genes Evol |
| Title: |
Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene. |
| Volume: |
209 |
| Issue: |
9 |
| Pages: |
537-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamada R |
| Year: |
2004 |
| Journal: |
Dev Biol |
| Title: |
Requirement for Mab21l2 during development of murine retina and ventral body wall. |
| Volume: |
274 |
| Issue: |
2 |
| Pages: |
295-307 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mathers PH |
| Year: |
1997 |
| Journal: |
Nature |
| Title: |
The Rx homeobox gene is essential for vertebrate eye development. |
| Volume: |
387 |
| Issue: |
6633 |
| Pages: |
603-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qiao J |
| Year: |
2022 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion. |
| Volume: |
119 |
| Issue: |
7 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishiguchi KM |
| Year: |
2007 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
The role of VEGF and VEGFR2/Flk1 in proliferation of retinal progenitor cells in murine retinal degeneration. |
| Volume: |
48 |
| Issue: |
9 |
| Pages: |
4315-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raciti M |
| Year: |
2013 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Reprogramming fibroblasts to neural-precursor-like cells by structured overexpression of pallial patterning genes. |
| Volume: |
57 |
|
| Pages: |
42-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kablar B |
| Year: |
2004 |
| Journal: |
Int J Dev Neurosci |
| Title: |
MyoD-lacZ transgenes are early markers in the neural retina, but MyoD function appears to be inhibited in the developing retinal cells. |
| Volume: |
22 |
| Issue: |
4 |
| Pages: |
215-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
Aberrant expression of a stabilized β-catenin mutant in keratocytes inhibits mouse corneal epithelial stratification. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
1919 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pöschl J |
| Year: |
2013 |
| Journal: |
Dev Biol |
| Title: |
Constitutive activation of β-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system. |
| Volume: |
374 |
| Issue: |
2 |
| Pages: |
319-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hallonet M |
| Year: |
1999 |
| Journal: |
Genes Dev |
| Title: |
Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. |
| Volume: |
13 |
| Issue: |
23 |
| Pages: |
3106-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inomata T |
| Year: |
2012 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Perlecan-deficient mutation impairs corneal epithelial structure. |
| Volume: |
53 |
| Issue: |
3 |
| Pages: |
1277-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cras-Méneur C |
| Year: |
2009 |
| Journal: |
Genes Dev |
| Title: |
Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window. |
| Volume: |
23 |
| Issue: |
17 |
| Pages: |
2088-101 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
O'Brien MP |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
SMC5 Plays Independent Roles in Congenital Heart Disease and Neurodevelopmental Disability. |
| Volume: |
25 |
| Issue: |
1 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song SY |
| Year: |
1999 |
| Journal: |
Gastroenterology |
| Title: |
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. |
| Volume: |
117 |
| Issue: |
6 |
| Pages: |
1416-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wei B |
| Year: |
2011 |
| Journal: |
Eur J Neurosci |
| Title: |
Emx1-expressing neural stem cells in the subventricular zone give rise to new interneurons in the ischemic injured striatum. |
| Volume: |
33 |
| Issue: |
5 |
| Pages: |
819-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grebbin BM |
| Year: |
2016 |
| Journal: |
Development |
| Title: |
Pbx1 is required for adult subventricular zone neurogenesis. |
| Volume: |
143 |
| Issue: |
13 |
| Pages: |
2281-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bender H |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus. |
| Volume: |
9 |
|
| Pages: |
691560 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burnett LC |
| Year: |
2017 |
| Journal: |
Hum Mol Genet |
| Title: |
Loss of the imprinted, non-coding Snord116 gene cluster in the interval deleted in the Prader Willi syndrome results in murine neuronal and endocrine pancreatic developmental phenotypes. |
| Volume: |
26 |
| Issue: |
23 |
| Pages: |
4606-4616 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gajewska KA |
| Year: |
2022 |
| Journal: |
Cells |
| Title: |
Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation. |
| Volume: |
11 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Flach H |
| Year: |
2018 |
| Journal: |
Dev Dyn |
| Title: |
Nosip functions during vertebrate eye and cranial cartilage development. |
| Volume: |
247 |
| Issue: |
9 |
| Pages: |
1070-1082 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lopez-Noriega L |
| Year: |
2021 |
| Journal: |
bioRxiv |
| Title: |
The long non-coding RNA Pax6os1/PAX6-AS1 modulates pancreatic beta-cell identity and function. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
2023 |
| Journal: |
FASEB J |
| Title: |
Loss of aquaporin 5 contributes to the corneal epithelial pathogenesis via Wnt/β-catenin pathway. |
| Volume: |
37 |
| Issue: |
2 |
| Pages: |
e22776 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mona B |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Regulating the dorsal neural tube expression of Ptf1a through a distal 3' enhancer. |
| Volume: |
418 |
| Issue: |
1 |
| Pages: |
216-225 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang YF |
| Year: |
2022 |
| Journal: |
Front Cell Neurosci |
| Title: |
MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1. |
| Volume: |
16 |
|
| Pages: |
866020 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karam SD |
| Year: |
2001 |
| Journal: |
J Comp Neurol |
| Title: |
Granule cells migrate within raphes in the developing cerebellum: an evolutionarily conserved morphogenic event. |
| Volume: |
440 |
| Issue: |
2 |
| Pages: |
127-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chalepakis G |
| Year: |
1995 |
| Journal: |
Gene |
| Title: |
Identification of DNA recognition sequences for the Pax3 paired domain. |
| Volume: |
162 |
| Issue: |
2 |
| Pages: |
267-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cecchi C |
| Year: |
2002 |
| Journal: |
Gene |
| Title: |
Emx2: a gene responsible for cortical development, regionalization and area specification. |
| Volume: |
291 |
| Issue: |
1-2 |
| Pages: |
1-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brimnes MK |
| Year: |
2002 |
| Journal: |
J Autoimmun |
| Title: |
Low expression of insulin in the thymus of non-obese diabetic mice. |
| Volume: |
19 |
| Issue: |
4 |
| Pages: |
203-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bréjot T |
| Year: |
2006 |
| Journal: |
Exp Neurol |
| Title: |
Forced expression of the motor neuron determinant HB9 in neural stem cells affects neurogenesis. |
| Volume: |
198 |
| Issue: |
1 |
| Pages: |
167-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsui S |
| Year: |
2012 |
| Journal: |
Exp Cell Res |
| Title: |
CTCF mediates effect of insulin on glucagon expression. |
| Volume: |
318 |
| Issue: |
8 |
| Pages: |
887-95 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao X |
| Year: |
2012 |
| Journal: |
Mol Biol Cell |
| Title: |
Specification and maintenance of oligodendrocyte precursor cells from neural progenitor cells: involvement of microRNA-7a. |
| Volume: |
23 |
| Issue: |
15 |
| Pages: |
2867-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eda H |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Effect of Helicobacter pylori infection on the link between GLP-1 expression and motility of the gastrointestinal tract. |
| Volume: |
12 |
| Issue: |
5 |
| Pages: |
e0177232 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Walker H |
| Year: |
2021 |
| Journal: |
Int J Mol Sci |
| Title: |
Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. |
| Volume: |
22 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hall HN |
| Year: |
2022 |
| Journal: |
PLoS One |
| Title: |
Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. |
| Volume: |
17 |
| Issue: |
11 |
| Pages: |
e0268149 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye DZ |
| Year: |
2009 |
| Journal: |
Gastroenterology |
| Title: |
Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. |
| Volume: |
137 |
| Issue: |
6 |
| Pages: |
2052-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hagemann TL |
| Year: |
2005 |
| Journal: |
Hum Mol Genet |
| Title: |
Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction. |
| Volume: |
14 |
| Issue: |
16 |
| Pages: |
2443-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eberhard D |
| Year: |
2000 |
| Journal: |
EMBO J |
| Title: |
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. |
| Volume: |
19 |
| Issue: |
10 |
| Pages: |
2292-303 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
49
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
157
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
139
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
273
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
102
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
336
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bopp D |
| Year: |
1986 |
| Journal: |
Cell |
| Title: |
Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila. |
| Volume: |
47 |
| Issue: |
6 |
| Pages: |
1033-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baumgartner S |
| Year: |
1987 |
| Journal: |
Genes Dev |
| Title: |
Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis. |
| Volume: |
1 |
| Issue: |
10 |
| Pages: |
1247-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Underhill DA |
| Year: |
2000 |
| Journal: |
Biochem Cell Biol |
| Title: |
Genetic and biochemical diversity in the Pax gene family. |
| Volume: |
78 |
| Issue: |
5 |
| Pages: |
629-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Apuzzo S |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding. |
| Volume: |
279 |
| Issue: |
32 |
| Pages: |
33601-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pontoriero GF |
| Year: |
2009 |
| Journal: |
Dev Biol |
| Title: |
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. |
| Volume: |
326 |
| Issue: |
2 |
| Pages: |
403-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Matos-Rodrigues GE |
| Year: |
2020 |
| Journal: |
Dis Model Mech |
| Title: |
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome. |
| Volume: |
13 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim YS |
| Year: |
2008 |
| Journal: |
Neuron |
| Title: |
p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. |
| Volume: |
59 |
| Issue: |
5 |
| Pages: |
746-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Donovan SL |
| Year: |
2012 |
| Journal: |
Mol Biol Cell |
| Title: |
Retinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells. |
| Volume: |
23 |
| Issue: |
22 |
| Pages: |
4362-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu N |
| Year: |
2017 |
| Journal: |
J Clin Invest |
| Title: |
A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence. |
| Volume: |
127 |
| Issue: |
3 |
| Pages: |
888-898 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu H |
| Year: |
2007 |
| Journal: |
Dev Biol |
| Title: |
Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling. |
| Volume: |
308 |
| Issue: |
1 |
| Pages: |
54-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ouchi Y |
| Year: |
2011 |
| Journal: |
Mol Cell Neurosci |
| Title: |
β-Catenin signaling regulates the timing of cell differentiation in mouse retinal progenitor cells. |
| Volume: |
46 |
| Issue: |
4 |
| Pages: |
770-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miller LA |
| Year: |
2006 |
| Journal: |
BMC Dev Biol |
| Title: |
Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice. |
| Volume: |
6 |
|
| Pages: |
14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li J |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e0159639 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wenzel PL |
| Year: |
2011 |
| Journal: |
Dev Biol |
| Title: |
Cell proliferation in the absence of E2F1-3. |
| Volume: |
351 |
| Issue: |
1 |
| Pages: |
35-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jia J |
| Year: |
2007 |
| Journal: |
Mol Cell Biol |
| Title: |
The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. |
| Volume: |
27 |
| Issue: |
20 |
| Pages: |
7236-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu Z |
| Year: |
2018 |
| Journal: |
J Int Med Res |
| Title: |
Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway. |
| Volume: |
46 |
| Issue: |
7 |
| Pages: |
2843-2855 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen D |
| Year: |
2004 |
| Journal: |
Cancer Cell |
| Title: |
Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. |
| Volume: |
5 |
| Issue: |
6 |
| Pages: |
539-51 |
|
•
•
•
•
•
|
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