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Search results 6801 to 6900 out of 7122 for App

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Type Details Score
Publication
12895417 | J:84847
First Author: Oddo S
Year: 2003
Journal: Neuron
Title: Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
Volume: 39
Issue: 3
Pages: 409-21
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Publication
38243688 | J:350730
First Author: Yamada C
Year: 2024
Journal: J Periodontal Res
Title: Dementia exacerbates periodontal bone loss in females.
Volume: 59
Issue: 3
Pages: 512-520
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Publication
38539620 | J:350679
 
First Author: Zhang W
Year: 2024
Journal: Brain Sci
Title: Dendrobine Ameliorates Alzheimer's Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice.
Volume: 14
Issue: 3
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Publication
26503550 | J:269053
 
First Author: Yang SH
Year: 2015
Journal: Sci Rep
Title: Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model.
Volume: 5
Pages: 15703
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Publication
27897204 | J:287498
 
First Author: Oka S
Year: 2016
Journal: Sci Rep
Title: Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease.
Volume: 6
Pages: 37889
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Publication
38500108 | J:350688
First Author: Jagadeesan N
Year: 2024
Journal: J Transl Med
Title: Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer's disease mice.
Volume: 22
Issue: 1
Pages: 291
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Publication
17251414 | J:117782
First Author: Billings LM
Year: 2007
Journal: J Neurosci
Title: Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.
Volume: 27
Issue: 4
Pages: 751-61
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Publication
38486986 | J:350690
First Author: Li Y
Year: 2024
Journal: Acta Pharm Sin B
Title: Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis.
Volume: 14
Issue: 3
Pages: 1380-1399
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Publication
27189884 | J:235964
 
First Author: Michalski D
Year: 2016
Journal: Neuroscience
Title: Decline of microtubule-associated protein tau after experimental stroke in differently aged wild-type and 3xTg mice with Alzheimer-like alterations.
Volume: 330
Pages: 1-11
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Publication
32993686 | J:313508
First Author: Robison LS
Year: 2020
Journal: J Neuroinflammation
Title: Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 17
Issue: 1
Pages: 285
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Publication
19605645 | J:151572
First Author: Ma QL
Year: 2009
Journal: J Neurosci
Title: Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.
Volume: 29
Issue: 28
Pages: 9078-89
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Publication
18423383 | J:136275
First Author: Resende R
Year: 2008
Journal: Free Radic Biol Med
Title: Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.
Volume: 44
Issue: 12
Pages: 2051-7
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Publication
36012331 | J:327939
 
First Author: Saleh B
Year: 2022
Journal: Int J Mol Sci
Title: FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer's Disease.
Volume: 23
Issue: 16
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Publication
33052247 | J:313523
First Author: Shen Y
Year: 2020
Journal: Theranostics
Title: Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease.
Volume: 10
Issue: 25
Pages: 11794-11819
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Publication
17904250 | J:149579
First Author: Knuesel I
Year: 2009
Journal: Neurobiol Aging
Title: Age-related accumulation of Reelin in amyloid-like deposits.
Volume: 30
Issue: 5
Pages: 697-716
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Publication
22960314 | J:192478
 
First Author: Algarzae N
Year: 2012
Journal: Neuroscience
Title: Parkin prevents cortical atrophy and Aβ-induced alterations of brain metabolism: ¹³C NMR and magnetic resonance imaging studies in AD models.
Volume: 225
Pages: 22-34
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Publication
30594047 | J:276151
 
First Author: Shentu YP
Year: 2019
Journal: Neurobiol Aging
Title: CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits.
Volume: 75
Pages: 198-208
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Publication
25582787 | J:219735
 
First Author: Barr CM
Year: 2015
Journal: Neurosci Lett
Title: Submyeloablative conditioning with busulfan permits bone marrow-derived cell accumulation in a murine model of Alzheimer's disease.
Volume: 588
Pages: 196-201
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Publication
29920240 | J:272426
First Author: Sejimo S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Scallop-derived plasmalogens attenuate the activation of PKCδ associated with the brain inflammation.
Volume: 503
Issue: 2
Pages: 837-842
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Publication
36052130 | J:327932
 
First Author: Bjorkli C
Year: 2022
Journal: Front Pharmacol
Title: Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer's disease pathology in mice.
Volume: 13
Pages: 913971
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Publication
38400523 | J:350700
First Author: Liu J
Year: 2024
Journal: FEBS J
Title: Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β-catenin signaling pathway.
Volume: 291
Issue: 10
Pages: 2221-2241
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Publication
25362032 | J:360690
First Author: Acquaah-Mensah GK
Year: 2015
Journal: J Alzheimers Dis
Title: A regulatory role for the insulin- and BDNF-linked RORA in the hippocampus: implications for Alzheimer's disease.
Volume: 44
Issue: 3
Pages: 827-38
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Publication
30071370 | J:271557
 
First Author: Bourgeois A
Year: 2018
Journal: Neurobiol Aging
Title: Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.
Volume: 71
Pages: 21-31
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Publication
37091517 | J:345692
 
First Author: Batista A
Year: 2023
Journal: Front Aging Neurosci
Title: Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease.
Volume: 15
Pages: 1161847
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Publication
27173425 | J:249651
First Author: Hayashi-Park E
Year: 2017
Journal: Behav Brain Res
Title: Experimentally induced diabetes worsens neuropathology, but not learning and memory, in middle aged 3xTg mice.
Volume: 322
Issue: Pt B
Pages: 280-287
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Publication
28411106 | J:256732
First Author: Esteve C
Year: 2017
Journal: Biochim Biophys Acta
Title: Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3×Tg Alzheimer mouse model.
Volume: 1865
Issue: 7
Pages: 747-754
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Publication
18068923 | J:135291
First Author: Sensi SL
Year: 2008
Journal: Exp Gerontol
Title: Altered oxidant-mediated intraneuronal zinc mobilization in a triple transgenic mouse model of Alzheimer's disease.
Volume: 43
Issue: 5
Pages: 488-92
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Publication
39351497 | J:359235
 
First Author: McNerney MW
Year: 2023
Journal: Exp Gerontol
Title: Memory-related hippocampal brain-derived neurotrophic factor activation pathways from repetitive transcranial magnetic stimulation in the 3xTg-AD mouse line.
Volume: 183
Pages: 112323
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Publication
39253611 | J:360716
First Author: Qian K
Year: 2024
Journal: Asian J Pharm Sci
Title: Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease.
Volume: 19
Issue: 4
Pages: 100938
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Publication
37586250 | J:339654
 
First Author: Sangineto M
Year: 2023
Journal: Redox Biol
Title: Metabolic reprogramming in inflammatory microglia indicates a potential way of targeting inflammation in Alzheimer's disease.
Volume: 66
Pages: 102846
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Publication
35443751 | J:324344
First Author: Hamilton LK
Year: 2022
Journal: Nat Commun
Title: Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer's disease mouse model.
Volume: 13
Issue: 1
Pages: 2061
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Publication
31103943 | J:281609
 
First Author: Castano-Prat P
Year: 2019
Journal: Neurobiol Aging
Title: Altered slow (<1 Hz) and fast (beta and gamma) neocortical oscillations in the 3xTg-AD mouse model of Alzheimer's disease under anesthesia.
Volume: 79
Pages: 142-151
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Publication
33771205 | J:360691
First Author: Koh SH
Year: 2021
Journal: Alzheimers Res Ther
Title: Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer's disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial.
Volume: 13
Issue: 1
Pages: 66
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Publication
27105281 | J:350774
First Author: Chu TT
Year: 2016
Journal: Cell Chem Biol
Title: Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation.
Volume: 23
Issue: 4
Pages: 453-61
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Publication
39225174 | J:360719
First Author: Yu L
Year: 2024
Journal: Phytother Res
Title: Thonningianin A from Penthorum chinense Pursh as a targeted inhibitor of Alzheimer's disease-related β-amyloid and Tau proteins.
Volume: 38
Issue: 9
Pages: 4815-4831
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Publication
23500896 | J:197528
 
First Author: Davis KE
Year: 2013
Journal: Behav Brain Res
Title: Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice.
Volume: 254
Pages: 73-82
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Publication
39532829 | J:360717
     
First Author: Wu CY
Year: 2024
Journal: Geroscience
Title: ACSL3 is a promising therapeutic target for alleviating anxiety and depression in Alzheimer's disease.
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Publication
21918687 | J:176128
First Author: Chen S
Year: 2011
Journal: PLoS One
Title: Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
Volume: 6
Issue: 8
Pages: e24293
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Publication
34879266 | J:321535
First Author: Han J
Year: 2021
Journal: Cell Rep
Title: Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease.
Volume: 37
Issue: 10
Pages: 110102
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Publication
16687509 | J:108684
First Author: Stutzmann GE
Year: 2006
Journal: J Neurosci
Title: Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.
Volume: 26
Issue: 19
Pages: 5180-9
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Publication
35431906 | J:323889
 
First Author: Carvalho da Silva AM
Year: 2022
Journal: Front Aging Neurosci
Title: Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Volume: 14
Pages: 835885
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Publication
19914182 | J:155589
First Author: Zhang YW
Year: 2009
Journal: Neuron
Title: A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation.
Volume: 64
Issue: 3
Pages: 328-40
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Publication
37185578 | J:350062
First Author: Noel RL
Year: 2023
Journal: Sci Rep
Title: Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.
Volume: 13
Issue: 1
Pages: 6757
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Publication
39448026 | J:360699
 
First Author: Carvalho D
Year: 2025
Journal: J Proteomics
Title: Untargeted metabolomics of 3xTg-AD neurotoxic astrocytes.
Volume: 310
Pages: 105336
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Publication
35961538 | J:328004
 
First Author: Castillo-Mariqueo L
Year: 2022
Journal: Behav Brain Res
Title: Clasping, ledge-score coordination and early gait impairments as primary behavioural markers of functional impairment in Alzheimer's disease.
Volume: 435
Pages: 114054
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Publication
27255814 | J:234996
 
First Author: Vandal M
Year: 2016
Journal: Neurobiol Aging
Title: Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease.
Volume: 43
Pages: 47-57
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Publication
31427599 | J:284641
First Author: Park SJ
Year: 2019
Journal: Sci Rep
Title: Visualizing Alzheimer's Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7.
Volume: 9
Issue: 1
Pages: 12052
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Publication
25093460 | J:215753
First Author: Xu J
Year: 2014
Journal: PLoS Biol
Title: Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 8
Pages: e1001923
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Publication
19561098 | J:151661
First Author: Fonseca MI
Year: 2009
Journal: J Immunol
Title: Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease.
Volume: 183
Issue: 2
Pages: 1375-83
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Publication
27103531 | J:235027
 
First Author: Moreno-Castilla P
Year: 2016
Journal: Neurobiol Aging
Title: Dopaminergic neurotransmission dysfunction induced by amyloid-β transforms cortical long-term potentiation into long-term depression and produces memory impairment.
Volume: 41
Pages: 187-199
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Publication
20505094 | J:160821
First Author: Clinton LK
Year: 2010
Journal: J Neurosci
Title: Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline.
Volume: 30
Issue: 21
Pages: 7281-9
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Publication
24244584 | J:209696
First Author: Ding F
Year: 2013
Journal: PLoS One
Title: Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Volume: 8
Issue: 11
Pages: e79977
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Publication
23683389 | J:284655
First Author: Giannopoulos PF
Year: 2013
Journal: Biol Psychiatry
Title: 5-lipoxygenase activating protein reduction ameliorates cognitive deficit, synaptic dysfunction, and neuropathology in a mouse model of Alzheimer's disease.
Volume: 74
Issue: 5
Pages: 348-56
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Publication
25731615 | J:221193
First Author: Kamphuis W
Year: 2015
Journal: Glia
Title: GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease.
Volume: 63
Issue: 6
Pages: 1036-56
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Publication
25253847 | J:216611
First Author: Liu Y
Year: 2014
Journal: J Neurosci
Title: IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology.
Volume: 34
Issue: 39
Pages: 12982-99
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Publication
32579923 | J:298885
First Author: Socodato R
Year: 2020
Journal: Cell Rep
Title: Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration.
Volume: 31
Issue: 12
Pages: 107796
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Publication
23831297 | J:200093
First Author: Yang Y
Year: 2013
Journal: Am J Pathol
Title: APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease.
Volume: 183
Issue: 3
Pages: 905-17
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Publication
39657671 | J:361249
First Author: Matera A
Year: 2025
Journal: Immunity
Title: Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus.
Volume: 58
Issue: 1
Pages: 197-217.e13
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Publication
28869476 | J:272696
First Author: Javidnia M
Year: 2017
Journal: J Alzheimers Dis
Title: Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.
Volume: 60
Issue: 2
Pages: 461-481
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Publication
32508844 | J:305735
 
First Author: Joly-Amado A
Year: 2020
Journal: Front Immunol
Title: CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy.
Volume: 11
Pages: 997
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Publication
14642273 | J:104240
First Author: Cruz JC
Year: 2003
Journal: Neuron
Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.
Volume: 40
Issue: 3
Pages: 471-83
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Publication
36536457 | J:338954
First Author: Kim DW
Year: 2022
Journal: Mol Neurodegener
Title: Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Volume: 17
Issue: 1
Pages: 83
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Publication
23884929 | J:199798
First Author: Cheng N
Year: 2013
Journal: J Neurosci
Title: Olfactory functions scale with circuit restoration in a rapidly reversible Alzheimer's disease model.
Volume: 33
Issue: 30
Pages: 12208-17
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Publication
23636056 | J:204766
First Author: Sandy AR
Year: 2013
Journal: J Immunol
Title: T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells.
Volume: 190
Issue: 11
Pages: 5818-28
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Publication
31727829 | J:281685
First Author: Zhu PJ
Year: 2019
Journal: Science
Title: Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome.
Volume: 366
Issue: 6467
Pages: 843-849
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Publication
21712989 | J:288163
First Author: Takeuchi H
Year: 2011
Journal: PLoS One
Title: Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease.
Volume: 6
Issue: 6
Pages: e21108
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Publication
18463254 | J:135174
First Author: Meilandt WJ
Year: 2008
Journal: J Neurosci
Title: Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease.
Volume: 28
Issue: 19
Pages: 5007-17
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Publication
32778161 | J:353258
First Author: Farmer KM
Year: 2020
Journal: Acta Neuropathol Commun
Title: P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 132
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Publication
22836259 | J:186543
First Author: Larson ME
Year: 2012
Journal: J Neurosci
Title: Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Volume: 32
Issue: 30
Pages: 10253-66
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Publication
29162816 | J:256308
First Author: Zhu H
Year: 2017
Journal: Nat Commun
Title: Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses.
Volume: 8
Issue: 1
Pages: 1676
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Publication
37714307 | J:341241
 
First Author: Lisgaras CP
Year: 2023
Journal: Neurobiol Dis
Title: Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum.
Volume: 187
Pages: 106294
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Publication
22323736 | J:181688
First Author: Cramer PE
Year: 2012
Journal: Science
Title: ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.
Volume: 335
Issue: 6075
Pages: 1503-6
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Publication
17234594 | J:117413
First Author: Kim J
Year: 2007
Journal: J Neurosci
Title: Abeta40 inhibits amyloid deposition in vivo.
Volume: 27
Issue: 3
Pages: 627-33
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Publication
33482356 | J:307763
 
First Author: Marquez A
Year: 2021
Journal: Neurobiol Dis
Title: Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
Volume: 151
Pages: 105273
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Publication
30617325 | J:295032
First Author: Lourenco MV
Year: 2019
Journal: Nat Med
Title: Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Volume: 25
Issue: 1
Pages: 165-175
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Publication
22293606 | J:182294
First Author: Guedj F
Year: 2012
Journal: Neurobiol Dis
Title: DYRK1A: a master regulatory protein controlling brain growth.
Volume: 46
Issue: 1
Pages: 190-203
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23512985 | J:198546
First Author: Laguna A
Year: 2013
Journal: Hum Mol Genet
Title: Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome.
Volume: 22
Issue: 14
Pages: 2775-84
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Publication
32783810 | J:298653
   
First Author: Zorrilla de San Martin J
Year: 2020
Journal: Elife
Title: Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome.
Volume: 9
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Publication
35780436 | J:345459
First Author: Deng Y
Year: 2022
Journal: Acta Neuropathol
Title: Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Volume: 144
Issue: 4
Pages: 637-650
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Publication
25706990 | J:226301
First Author: Brendel M
Year: 2015
Journal: PLoS One
Title: Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models.
Volume: 10
Issue: 2
Pages: e0116678
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Publication
20864679 | J:166257
First Author: Lee S
Year: 2010
Journal: Am J Pathol
Title: CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.
Volume: 177
Issue: 5
Pages: 2549-62
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Publication
20813165 | J:169720
First Author: Mei X
Year: 2010
Journal: Neuroscience
Title: Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Volume: 171
Issue: 1
Pages: 92-105
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Publication
22522613 | J:196823
First Author: Zhang Y
Year: 2012
Journal: Diabetes
Title: Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.
Volume: 61
Issue: 6
Pages: 1434-43
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Publication
19720431 | J:173732
First Author: Montgomery KS
Year: 2011
Journal: Neurobiol Aging
Title: Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research.
Volume: 32
Issue: 7
Pages: 1273-85
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32079659 | J:290161
 
First Author: Oudart M
Year: 2020
Journal: J Cell Sci
Title: AstroDot - a new method for studying the spatial distribution of mRNA in astrocytes.
Volume: 133
Issue: 7
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32601313 | J:296369
First Author: Henjum K
Year: 2020
Journal: Sci Rep
Title: Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody.
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Pages: 10590
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Title: Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
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21951279 | J:178473
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Year: 2011
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Title: Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo.
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Title: Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
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27029737 | J:242434
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Title: Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.
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17897742 | J:128743
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Journal: Neurosci Res
Title: Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms.
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19297404 | J:156661
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Journal: Hum Mol Genet
Title: Down syndrome--recent progress and future prospects.
Volume: 18
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17050550 | J:117029
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Year: 2007
Journal: Hum Reprod
Title: Impact of trisomy on fertility and meiosis in male mice.
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Issue: 2
Pages: 468-76
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Publication
18629032 | J:208905
First Author: Forejt J
Year: 2003
Journal: Comp Funct Genomics
Title: Segmental trisomy of mouse chromosome 17: introducing an alternative model of Down's syndrome.
Volume: 4
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Publication
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First Author: Souchet B
Year: 2014
Journal: Neurobiol Dis
Title: Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.
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20231476 | J:158919
First Author: Heneka MT
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Journal: Proc Natl Acad Sci U S A
Title: Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
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30040874 | J:272683
     
First Author: Granger MW
Year: 2018
Journal: J Neurochem
Title: Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's disease mouse models.
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Publication
21695208 | J:174789
First Author: Butler D
Year: 2011
Journal: PLoS One
Title: Protective effects of positive lysosomal modulation in Alzheimer's disease transgenic mouse models.
Volume: 6
Issue: 6
Pages: e20501
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Genotype
Genotype
Symbol: Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background: B6.Cg-Psen1 Tg(APPSwe,tauP301L)1Lfa
Zygosity: cx
Has Mutant Allele: true
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Protein
P49769
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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