| Type |
Details |
Score |
| Publication |
| First Author: |
Randeria PS |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown. |
| Volume: |
112 |
| Issue: |
18 |
| Pages: |
5573-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soucheray M |
| Year: |
2015 |
| Journal: |
Cancer Res |
| Title: |
Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition. |
| Volume: |
75 |
| Issue: |
20 |
| Pages: |
4372-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tang Y |
| Year: |
2015 |
| Journal: |
Neuroscience |
| Title: |
EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus. |
| Volume: |
304 |
|
| Pages: |
109-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Slyke P |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk. |
| Volume: |
25 |
| Issue: |
9 |
| Pages: |
3831-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meabon JS |
| Year: |
2016 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling. |
| Volume: |
70 |
|
| Pages: |
1-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hao X |
| Year: |
2016 |
| Journal: |
Biol Reprod |
| Title: |
Epidermal Growth Factor-Mobilized Intracellular Calcium of Cumulus Cells Decreases Natriuretic Peptide Receptor 2 Affinity for Natriuretic Peptide Type C and Induces Oocyte Meiotic Resumption in the Mouse. |
| Volume: |
95 |
| Issue: |
2 |
| Pages: |
45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jitsukawa S |
| Year: |
2017 |
| Journal: |
J Pathol |
| Title: |
Loss of sorting nexin 5 stabilizes internalized growth factor receptors to promote thyroid cancer progression. |
| Volume: |
243 |
| Issue: |
3 |
| Pages: |
342-353 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dai K |
| Year: |
2015 |
| Journal: |
Immunology |
| Title: |
Amphiregulin promotes the immunosuppressive activity of intrahepatic CD4+ regulatory T cells to impair CD8+ T-cell immunity against hepatitis B virus infection. |
| Volume: |
144 |
| Issue: |
3 |
| Pages: |
506-517 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang W |
| Year: |
2017 |
| Journal: |
Neuroscience |
| Title: |
Macrophage migration inhibitory factor mediates viability and apoptosis of PVM/Ms through PI3K/Akt pathway. |
| Volume: |
360 |
|
| Pages: |
220-229 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hsu JY |
| Year: |
2017 |
| Journal: |
FASEB J |
| Title: |
Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin. |
| Volume: |
31 |
| Issue: |
10 |
| Pages: |
4265-4276 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Islam MS |
| Year: |
2016 |
| Journal: |
Br J Pharmacol |
| Title: |
Epidermal growth factor is a critical regulator of the cytokine IL-33 in intestinal epithelial cells. |
| Volume: |
173 |
| Issue: |
16 |
| Pages: |
2532-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ichise T |
| Year: |
2010 |
| Journal: |
Cell Struct Funct |
| Title: |
Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth. |
| Volume: |
35 |
| Issue: |
1 |
| Pages: |
3-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dubé PE |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
9119 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mapes J |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Aberrantly high expression of the CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in mammary epithelium leads to breast tumorigenesis. |
| Volume: |
293 |
| Issue: |
8 |
| Pages: |
2850-2864 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Meza-Carmen V |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Regulation of growth factor receptor degradation by ADP-ribosylation factor domain protein (ARD) 1. |
| Volume: |
108 |
| Issue: |
26 |
| Pages: |
10454-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gosney JA |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Proteomics reveals novel protein associations with early endosomes in an epidermal growth factor-dependent manner. |
| Volume: |
293 |
| Issue: |
16 |
| Pages: |
5895-5908 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Breit A |
| Year: |
2018 |
| Journal: |
J Biol Chem |
| Title: |
Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. |
| Volume: |
293 |
| Issue: |
44 |
| Pages: |
17278-17290 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Namba H |
| Year: |
2017 |
| Journal: |
J Neurochem |
| Title: |
Epidermal growth factor signals attenuate phenotypic and functional development of neocortical GABA neurons. |
| Volume: |
142 |
| Issue: |
6 |
| Pages: |
886-900 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chmielewski M |
| Year: |
2019 |
| Journal: |
Sci Rep |
| Title: |
FimH-based display of functional eukaryotic proteins on bacteria surfaces. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
8410 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ogawa M |
| Year: |
2020 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking. |
| Volume: |
526 |
| Issue: |
1 |
| Pages: |
184-190 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fang T |
| Year: |
2020 |
| Journal: |
Blood |
| Title: |
Epidermal growth factor receptor-dependent DNA repair promotes murine and human hematopoietic regeneration. |
| Volume: |
136 |
| Issue: |
4 |
| Pages: |
441-454 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taniguchi T |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling. |
| Volume: |
288 |
| Issue: |
41 |
| Pages: |
29934-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ha Thi HT |
| Year: |
2015 |
| Journal: |
Mol Cell Biol |
| Title: |
Smad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl. |
| Volume: |
35 |
| Issue: |
16 |
| Pages: |
2841-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu M |
| Year: |
2019 |
| Journal: |
JCI Insight |
| Title: |
Nononcogenic restoration of the intestinal barrier by E. coli-delivered human EGF. |
| Volume: |
4 |
| Issue: |
16 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hsu TI |
| Year: |
2016 |
| Journal: |
Oncotarget |
| Title: |
Positive feedback regulation between IL10 and EGFR promotes lung cancer formation. |
| Volume: |
7 |
| Issue: |
15 |
| Pages: |
20840-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marino D |
| Year: |
2013 |
| Journal: |
J Dermatol Sci |
| Title: |
Activation of the epidermal growth factor receptor promotes lymphangiogenesis in the skin. |
| Volume: |
71 |
| Issue: |
3 |
| Pages: |
184-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schaberg E |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells. |
| Volume: |
9 |
|
| Pages: |
643060 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arai C |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains. |
| Volume: |
7 |
|
| Pages: |
45181 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sreekumar BK |
| Year: |
2014 |
| Journal: |
Pancreas |
| Title: |
Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions. |
| Volume: |
43 |
| Issue: |
8 |
| Pages: |
1256-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bae JA |
| Year: |
2016 |
| Journal: |
Clin Cancer Res |
| Title: |
Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
1284-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi Y |
| Year: |
2017 |
| Journal: |
Sci Rep |
| Title: |
Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization. |
| Volume: |
7 |
|
| Pages: |
42279 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Castro-Sánchez L |
| Year: |
2013 |
| Journal: |
Int J Biochem Cell Biol |
| Title: |
Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma. |
| Volume: |
45 |
| Issue: |
11 |
| Pages: |
2501-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karasawa Y |
| Year: |
2022 |
| Journal: |
Dev Growth Differ |
| Title: |
Growth factor dependence of the proliferation and survival of cultured lacrimal gland epithelial cells isolated from late-embryonic mice. |
| Volume: |
64 |
| Issue: |
3 |
| Pages: |
138-149 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li X |
| Year: |
2024 |
| Journal: |
bioRxiv |
| Title: |
Multi-omics delineate growth factor network underlying exercise effects in an Alzheimer's mouse model. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Daynac M |
| Year: |
2013 |
| Journal: |
Stem Cell Res |
| Title: |
Quiescent neural stem cells exit dormancy upon alteration of GABAAR signaling following radiation damage. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
516-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Deltagen Inc |
| Year: |
2005 |
| Journal: |
MGI Direct Data Submission |
| Title: |
NIH initiative supporting placement of Deltagen, Inc. mice into public repositories |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
401
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
219
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
247
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kasowitz SD |
| Year: |
2018 |
| Journal: |
PLoS Genet |
| Title: |
Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. |
| Volume: |
14 |
| Issue: |
5 |
| Pages: |
e1007412 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
202
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim J |
| Year: |
2010 |
| Journal: |
Mol Cell Biol |
| Title: |
The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors. |
| Volume: |
30 |
| Issue: |
7 |
| Pages: |
1582-92 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
171
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
171
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
90
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
171
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeon H |
| Year: |
2001 |
| Journal: |
Nat Struct Biol |
| Title: |
Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
499-504 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yurchenco PD |
| Year: |
2004 |
| Journal: |
Curr Opin Cell Biol |
| Title: |
Assembly and tissue functions of early embryonic laminins and netrins. |
| Volume: |
16 |
| Issue: |
5 |
| Pages: |
572-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kelley MR |
| Year: |
1987 |
| Journal: |
Cell |
| Title: |
Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus. |
| Volume: |
51 |
| Issue: |
4 |
| Pages: |
539-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindsell CE |
| Year: |
1995 |
| Journal: |
Cell |
| Title: |
Jagged: a mammalian ligand that activates Notch1. |
| Volume: |
80 |
| Issue: |
6 |
| Pages: |
909-17 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu H |
| Year: |
2005 |
| Journal: |
BMC Cell Biol |
| Title: |
A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin. |
| Volume: |
6 |
| Issue: |
1 |
| Pages: |
23 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [, , , , ]. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing, to name but a few []. Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target. This entry represents ZPR1-type zinc finger domains. An orthologous protein found once in each of the completed archaeal genomes corresponds to a zinc finger-containing domain repeated as the N-terminal and C-terminal halves of themouse protein ZPR1. ZPR1 is an experimentally proven zinc-binding protein that binds the tyrosine kinase domain of the epidermal growth factor receptor (EGFR); binding is inhibited by EGF stimulation and tyrosine phosphorylation, and activation by EGF is followed by some redistribution of ZPR1 to the nucleus. By analogy, other proteins with the ZPR1 zinc finger domain may be regulatory proteins that sense protein phosphorylation state and/or participate in signal transduction (see also ).Deficiencies in ZPR1 may contribute to neurodegenerative disorders. ZPR1 appears to be down-regulated in patients with spinal muscular atrophy (SMA), a disease characterised by degeneration of the alpha-motor neurons in the spinal cord that can arise from mutations affecting the expression of Survival Motor Neurons (SMN) []. ZPR1 interacts with complexes formed by SMN [], and may act as a modifier that effects the severity of SMA. |
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•
•
•
•
•
|
| Protein Domain |
| Type: |
Repeat |
| Description: |
The low-density lipoprotein receptor (LDLR) is the major cholesterol-carrying lipoprotein of plasma, acting to regulate cholesterol homeostasis in mammalian cells. The LDL receptor binds LDL and transports it into cells by acidic endocytosis. In order to be internalized, the receptor-ligand complex must first cluster into clathrin-coated pits. Once inside the cell, the LDLR separates from its ligand, which is degraded in the lysosomes, while the receptor returns to the cell surface []. The internal dissociation of the LDLR with its ligand is mediated by proton pumps within the walls of the endosome that lower the pH. The LDLR is a multi-domain protein, containing: The ligand-binding domain contains seven or eight 40-amino acid LDLR class A (cysteine-rich) repeats, each of which contains a coordinated calcium ion and six cysteine residues involved in disulphide bond formation []. Similar domains have been found in other extracellular and membrane proteins []. The second conserved region contains two EGF repeats, followed by six LDLR class B (YWTD) repeats, and another EGF repeat. The LDLR class B repeats each contain a conserved YWTD motif, and is predicted to form a β-propeller structure []. This region is critical for ligand release and recycling of the receptor [].The third domain is rich in serine and threonine residues and contains clustered O-linked carbohydrate chains.The fourth domain is the hydrophobic transmembrane region.The fifth domain is the cytoplasmic tail that directs the receptor to clathrin-coated pits.LDLR is closely related in structure to several other receptors, including LRP1, LRP1b, megalin/LRP2, VLDL receptor, lipoprotein receptor, MEGF7/LRP4, and LRP8/apolipoprotein E receptor2); these proteins participate in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment, and transport of nutrients and vitamins [].This entry represents the LDLR class A (cysteine-rich) repeat, which contains 6 disulphide-bound cysteines and a highly conserved cluster of negatively charged amino acids, of which many are clustered on one face of the module []. In LDL receptors, the class A domains form the binding site for LDL and calcium. The acidic residues between the fourth and sixth cysteines are important for high-affinity binding of positively charged sequences in LDLR's ligands. The repeat consists of a β-hairpin structure followed by a series of beta turns. In the absence of calcium, LDL-A domains are unstructured; the bound calcium ion imparts structural integrity. Following these repeats is a 350 residue domain that resembles part of the epidermal growth factor (EGF) precursor. Numerous familial hypercholesterolemia mutations of the LDL receptor alter the calcium coordinating residue of LDL-A domains or other crucial scaffolding residues. |
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•
•
•
•
•
|
| Protein Domain |
| Type: |
Repeat |
| Description: |
The low-density lipoprotein receptor (LDLR) is the major cholesterol-carrying lipoprotein of plasma, acting to regulate cholesterol homeostasis in mammalian cells. The LDL receptor binds LDL and transports it into cells by acidic endocytosis. In order to be internalized, the receptor-ligand complex must first cluster into clathrin-coated pits. Once inside the cell, the LDLR separates from its ligand, which is degraded in the lysosomes,while the receptor returns to the cell surface []. The internal dissociation of the LDLR with its ligand is mediated by proton pumps within the walls of the endosome that lower the pH. The LDLR is a multi-domain protein, containing: The ligand-binding domain contains seven or eight 40-amino acid LDLR class A (cysteine-rich) repeats, each of which contains a coordinated calcium ion and six cysteine residues involved in disulphide bond formation []. Similar domains have been found in other extracellular and membrane proteins []. The second conserved region contains two EGF repeats, followed by six LDLR class B (YWTD) repeats, and another EGF repeat. The LDLR class B repeats each contain a conserved YWTD motif, and is predicted to form a β-propeller structure []. This region is critical for ligand release and recycling of the receptor [].The third domain is rich in serine and threonine residues and contains clustered O-linked carbohydrate chains.The fourth domain is the hydrophobic transmembrane region.The fifth domain is the cytoplasmic tail that directs the receptor to clathrin-coated pits.LDLR is closely related in structure to several other receptors, including LRP1, LRP1b, megalin/LRP2, VLDL receptor, lipoprotein receptor, MEGF7/LRP4, and LRP8/apolipoprotein E receptor2); these proteins participate in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment, and transport of nutrients and vitamins [].This entry represents the LDLR classB (YWTD) repeat, the structure of which has been solved []. The six YWTD repeats together fold into a six-bladed β-propeller. Each blade of the propeller consists of four antiparallel β-strands; the innermost strand of each blade is labeled 1 and the outermost strand, 4. The sequence repeats are offset with respect to the blades of the propeller, such that any given 40-residue YWTD repeat spans strands 24 of one propeller blade and strand 1 of the subsequent blade. This offset ensures circularization of the propeller because the last strand of the final sequence repeat acts as an innermost strand 1 of the blade that harbors strands 24 from the first sequence repeat. The repeat is found in a variety of proteins that include, vitellogenin receptor from Drosophila melanogaster, low-density lipoprotein (LDL) receptor [], preproepidermal growth factor, and nidogen (entactin). |
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•
•
•
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| Publication |
| First Author: |
Kaiser K |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
1498 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Najarro EH |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. |
| Volume: |
147 |
| Issue: |
19 |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Tulloch AJ |
| Year: |
2019 |
| Journal: |
J Comp Neurol |
| Title: |
Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse. |
| Volume: |
527 |
| Issue: |
18 |
| Pages: |
2948-2972 |
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•
•
•
•
|
| Publication |
| First Author: |
Yu C |
| Year: |
2016 |
| Journal: |
Cell Res |
| Title: |
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. |
| Volume: |
26 |
| Issue: |
3 |
| Pages: |
275-87 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
486
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee S |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. |
| Volume: |
147 |
| Issue: |
21 |
|
|
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•
•
•
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| Publication |
| First Author: |
Ru J |
| Year: |
2020 |
| Journal: |
Invest Ophthalmol Vis Sci |
| Title: |
Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis. |
| Volume: |
61 |
| Issue: |
13 |
| Pages: |
6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helbig C |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Notch controls the magnitude of T helper cell responses by promoting cellular longevity. |
| Volume: |
109 |
| Issue: |
23 |
| Pages: |
9041-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koenig SN |
| Year: |
2016 |
| Journal: |
J Am Heart Assoc |
| Title: |
Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract. |
| Volume: |
5 |
| Issue: |
4 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takeshita K |
| Year: |
2007 |
| Journal: |
Circ Res |
| Title: |
Critical role of endothelial Notch1 signaling in postnatal angiogenesis. |
| Volume: |
100 |
| Issue: |
1 |
| Pages: |
70-8 |
|
•
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•
•
•
|
| Publication |
| First Author: |
Liu Z |
| Year: |
2015 |
| Journal: |
Development |
| Title: |
The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. |
| Volume: |
142 |
| Issue: |
14 |
| Pages: |
2452-63 |
|
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•
•
•
|
| Publication |
| First Author: |
Hilton MJ |
| Year: |
2008 |
| Journal: |
Nat Med |
| Title: |
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. |
| Volume: |
14 |
| Issue: |
3 |
| Pages: |
306-14 |
|
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•
•
•
|
| Publication |
| First Author: |
Boyle SC |
| Year: |
2014 |
| Journal: |
Development |
| Title: |
Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development. |
| Volume: |
141 |
| Issue: |
2 |
| Pages: |
346-54 |
|
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•
•
•
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| Publication |
| First Author: |
Shamir A |
| Year: |
2012 |
| Journal: |
J Neurosci |
| Title: |
The importance of the NRG-1/ErbB4 pathway for synaptic plasticity and behaviors associated with psychiatric disorders. |
| Volume: |
32 |
| Issue: |
9 |
| Pages: |
2988-97 |
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•
•
•
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| Publication |
| First Author: |
Hastings RL |
| Year: |
2020 |
| Journal: |
Sci Rep |
| Title: |
Morphological remodeling during recovery of the neuromuscular junction from terminal Schwann cell ablation in adult mice. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
11132 |
|
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•
•
•
|
| Publication |
| First Author: |
Takeoka A |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. |
| Volume: |
27 |
| Issue: |
1 |
| Pages: |
71-85.e3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guy J |
| Year: |
2007 |
| Journal: |
Science |
| Title: |
Reversal of neurological defects in a mouse model of Rett syndrome. |
| Volume: |
315 |
| Issue: |
5815 |
| Pages: |
1143-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mamareli P |
| Year: |
2019 |
| Journal: |
Eur J Immunol |
| Title: |
Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile. |
| Volume: |
49 |
| Issue: |
5 |
| Pages: |
747-757 |
|
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•
•
•
|
| Publication |
| First Author: |
Soleilhavoup C |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
3111 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
223
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
713
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
686
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
115
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Munger JS |
| Year: |
1999 |
| Journal: |
Cell |
| Title: |
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. |
| Volume: |
96 |
| Issue: |
3 |
| Pages: |
319-28 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
412
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
517
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calvanese L |
| Year: |
2006 |
| Journal: |
J Med Chem |
| Title: |
Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala. |
| Volume: |
49 |
| Issue: |
24 |
| Pages: |
7054-62 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
65
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
165
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
46
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
109
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
108
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
151
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
689
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
133
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
79
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
517
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
296
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
495
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
244
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
714
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
441
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
517
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
239
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
699
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
80
 |
| Fragment?: |
false |
|
•
•
•
•
•
|