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Search results 701 to 723 out of 723 for Adk

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Hits by Strain

Type Details Score
Protein
F8WIC0
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: false
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Protein
A0A1B0GRV7
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
A2ARF6
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
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Protein
A0A0A6YXW8
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: true
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Protein
G3UYQ4
Organism: Mus musculus/domesticus
Length: 1894  
Fragment?: false
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Publication
23416111 | -
First Author: Amiri M
Year: 2013
Journal: Int J Biochem Cell Biol
Title: The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.
Volume: 45
Issue: 5
Pages: 925-31
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Publication
35649375 | J:326093
First Author: Han L
Year: 2022
Journal: Cell Rep
Title: Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine.
Volume: 39
Issue: 9
Pages: 110884
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Protein
P55264
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Protein
Q8BWS6
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
F6RP11
Organism: Mus musculus/domesticus
Length: 65  
Fragment?: true
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Protein
Q9R0Y5
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: false
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Protein
Q9WTP6
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
Q9D8W6
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q9WTP7
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: false
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Protein
F6TEU8
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Publication
30862176 | J:277460
 
First Author: Scemes E
Year: 2019
Journal: ASN Neuro
Title: Astrocyte and Neuronal Pannexin1 Contribute Distinctly to Seizures.
Volume: 11
Pages: 1759091419833502
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Publication
36473288 | J:344592
 
First Author: Zhang M
Year: 2023
Journal: J Mol Cell Cardiol
Title: Adenosine kinase promotes post-infarction cardiac repair by epigenetically maintaining reparative macrophage phenotype.
Volume: 174
Pages: 88-100
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Protein Domain
IPR036193 | ADK_active_lid_dom_sf
Type: Homologous_superfamily
Description: Adenylate kinases (ADK; ) are phosphotransferases that catalyse the Mg-dependent reversible conversion of ATP and AMP to two molecules of ADP, an essential reaction for many processes in living cells. In large variants of adenylate kinase, the AMP and ATP substrates are buried in a domain that undergoes conformational changes from an open to a closed state when bound to substrate; the ligand is then contained within a highly specific environment required for catalysis. Adenylate kinase is a 3-domain protein consisting of a large central CORE domain flanked by a LID domain on one side and the AMP-binding NMPbind domain on the other []. The LID domain binds ATP and covers the phosphates at the active site. The substrates first bind the CORE domain, followed by closure of the active site by the LID and NMPbind domains.Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organisms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues (two CX(n)C motifs) are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function [].The ADK LID domain structure has a Rubredoxin-like fold, which consists of a metal (zinc or iron)-bound fold.
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Protein
Q9WUR9
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q3UYL0
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: true
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Protein
Q3U489
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Publication
9715904 | -
First Author: Berry MB
Year: 1998
Journal: Proteins
Title: Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+.
Volume: 32
Issue: 3
Pages: 276-88
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Publication
17299745 | -
First Author: Snow C
Year: 2007
Journal: Proteins
Title: Essential dynamics sampling study of adenylate kinase: comparison to citrate synthase and implication for the hinge and shear mechanisms of domain motions.
Volume: 67
Issue: 2
Pages: 325-37
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