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Search results 701 to 800 out of 4449 for Apc

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
100885784 | amer1
Type: gene
Organism: zebrafish
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Gene
405847 | sapcd2
Type: gene
Organism: zebrafish
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Gene
703183 | AMER3
Type: gene
Organism: macaque, rhesus
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Gene
707231 | SAPCD2
Type: gene
Organism: macaque, rhesus
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Gene
707700 | AMER1
Type: gene
Organism: macaque, rhesus
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Gene
708730 | AMER2
Type: gene
Organism: macaque, rhesus
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Gene
716394 | SAPCD1
Type: gene
Organism: macaque, rhesus
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Gene
100491939 | amer3
Type: gene
Organism: frog, western clawed
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Gene
100495403 | amer1
Type: gene
Organism: frog, western clawed
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Gene
100038269 | amer2
Type: gene
Organism: frog, western clawed
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Gene
100487796 | sapcd1
Type: gene
Organism: frog, western clawed
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Gene
107975631 | LOC107975631
Type: gene
Organism: chimpanzee
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Gene
107976150 | LOC107976150
Type: gene
Organism: chimpanzee
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Gene
116406721 | sapcd2
Type: gene
Organism: frog, western clawed
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Gene
119864462 | AMER3
Type: gene
Organism: dog, domestic
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Gene
108698152 | LOC108698152
Type: gene
Organism: frog, African clawed
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Gene
108699886 | LOC108699886
Type: gene
Organism: frog, African clawed
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Gene
121396854 | LOC121396854
Type: gene
Organism: frog, African clawed
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Gene
134806963 | LOC134806963
Type: gene
Organism: chimpanzee
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Gene
137489341 | LOC137489341
Type: gene
Organism: zebrafish
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Publication
18316368 | J:137089
First Author: Lu Z
Year: 2008
Journal: J Biol Chem
Title: Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling.
Volume: 283
Issue: 19
Pages: 13132-9
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Publication
26503053 | J:226759
First Author: Gregorieff A
Year: 2015
Journal: Nature
Title: Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Volume: 526
Issue: 7575
Pages: 715-8
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Publication
35537038 | J:326290
First Author: Lee R
Year: 2022
Journal: Cancer Discov
Title: Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer.
Volume: 12
Issue: 7
Pages: 1702-1717
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Publication
16980623 | J:112972
First Author: Kohno M
Year: 2006
Journal: Mol Cell Biol
Title: Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation.
Volume: 26
Issue: 19
Pages: 7211-23
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Publication
28425994 | J:254425
First Author: Maddocks ODK
Year: 2017
Journal: Nature
Title: Modulating the therapeutic response of tumours to dietary serine and glycine starvation.
Volume: 544
Issue: 7650
Pages: 372-376
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Publication
20531296 | J:168378
First Author: Wilson CH
Year: 2010
Journal: Oncogene
Title: The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways.
Volume: 29
Issue: 32
Pages: 4567-75
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Publication
16204028 | J:101604
First Author: Li Q
Year: 2005
Journal: Cancer Res
Title: The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.
Volume: 65
Issue: 19
Pages: 8622-7
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Publication
38893159 | J:349875
 
First Author: Ghobashi AH
Year: 2024
Journal: Cancers (Basel)
Title: Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors.
Volume: 16
Issue: 11
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Publication
22665058 | J:197230
First Author: Radulescu S
Year: 2013
Journal: Oncogene
Title: Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation.
Volume: 32
Issue: 16
Pages: 2048-57
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Publication
23499052 | J:195346
First Author: Wu R
Year: 2013
Journal: Am J Pathol
Title: Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.
Volume: 182
Issue: 4
Pages: 1391-9
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Publication
29426940 | J:262663
First Author: Burke ZD
Year: 2018
Journal: Sci Rep
Title: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
Volume: 8
Issue: 1
Pages: 2735
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Publication
19861162 | J:156736
First Author: Varnat F
Year: 2010
Journal: Mech Dev
Title: Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling.
Volume: 127
Issue: 1-2
Pages: 73-81
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Publication
26327117 | J:227228
First Author: Shrestha A
Year: 2015
Journal: PLoS One
Title: Generation and Validation of miR-142 Knock Out Mice.
Volume: 10
Issue: 9
Pages: e0136913
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Publication
16621792 | J:114581
First Author: Sharma M
Year: 2006
Journal: J Biol Chem
Title: Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin.
Volume: 281
Issue: 25
Pages: 17140-9
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Publication
10330403 | J:55044
First Author: Fagotto F
Year: 1999
Journal: J Cell Biol
Title: Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.
Volume: 145
Issue: 4
Pages: 741-56
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Publication
27207656 | J:232782
First Author: Wang H
Year: 2016
Journal: Carcinogenesis
Title: Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Volume: 37
Issue: 7
Pages: 723-730
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Publication
28057765 | J:240425
First Author: Gao FJ
Year: 2017
Journal: Mol Biol Cell
Title: Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Volume: 28
Issue: 5
Pages: 587-599
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Publication
11212243 | J:67452
First Author: Wetmore C
Year: 2001
Journal: Cancer Res
Title: Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.
Volume: 61
Issue: 2
Pages: 513-6
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Publication
25270258 | J:259053
First Author: Phesse TJ
Year: 2014
Journal: Sci Signal
Title: Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Volume: 7
Issue: 345
Pages: ra92
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Publication
26679840 | J:227691
First Author: Cheung EC
Year: 2016
Journal: Genes Dev
Title: Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine.
Volume: 30
Issue: 1
Pages: 52-63
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Publication
39169180 | J:359275
First Author: Imada S
Year: 2024
Journal: Nature
Title: Short-term post-fast refeeding enhances intestinal stemness via polyamines.
Volume: 633
Issue: 8031
Pages: 895-904
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Publication
27708166 | J:238627
First Author: Tetteh PW
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.
Volume: 113
Issue: 42
Pages: 11859-11864
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Publication
11809702 | J:74003
First Author: Seno H
Year: 2002
Journal: Cancer Res
Title: Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps.
Volume: 62
Issue: 2
Pages: 506-11
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Publication
18716223 | J:138829
First Author: Purro SA
Year: 2008
Journal: J Neurosci
Title: Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli.
Volume: 28
Issue: 34
Pages: 8644-54
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Publication
23276799 | J:196908
First Author: Tanwar PS
Year: 2013
Journal: Carcinogenesis
Title: PTEN loss and HOXA10 expression are associated with ovarian endometrioid adenocarcinoma differentiation and progression.
Volume: 34
Issue: 4
Pages: 893-901
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Publication
18281465 | J:189983
First Author: Tran H
Year: 2008
Journal: Genes Dev
Title: Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
Volume: 22
Issue: 4
Pages: 528-42
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Publication
12941808 | J:85136
First Author: Takeda H
Year: 2003
Journal: Cancer Res
Title: Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis.
Volume: 63
Issue: 16
Pages: 4872-7
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Publication
23935526 | J:200592
First Author: Méniel V
Year: 2013
Journal: PLoS Genet
Title: Cited1 deficiency suppresses intestinal tumorigenesis.
Volume: 9
Issue: 8
Pages: e1003638
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Publication
14522940 | J:86036
First Author: Niho N
Year: 2003
Journal: Cancer Res
Title: Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands.
Volume: 63
Issue: 18
Pages: 6090-5
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Publication
23955081 | J:204354
First Author: Maynard MA
Year: 2014
Journal: Oncogene
Title: Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer.
Volume: 33
Issue: 28
Pages: 3742-7
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Publication
31148594 | J:310363
First Author: Tang J
Year: 2019
Journal: Lab Invest
Title: Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis.
Volume: 99
Issue: 10
Pages: 1454-1469
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Publication
35075245 | J:322769
First Author: Flum M
Year: 2022
Journal: Oncogene
Title: Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT.
Volume: 41
Issue: 10
Pages: 1492-1506
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Publication
32948837 | J:299456
First Author: López I
Year: 2020
Journal: Oncogene
Title: An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.
Volume: 39
Issue: 43
Pages: 6692-6703
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Publication
11507063 | J:70902
First Author: Lal G
Year: 2001
Journal: Cancer Res
Title: Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor.
Volume: 61
Issue: 16
Pages: 6131-6
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Publication
32941878 | J:314327
First Author: Lähde M
Year: 2021
Journal: Gastroenterology
Title: Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling.
Volume: 160
Issue: 1
Pages: 245-259
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Publication
10866310 | J:62926
First Author: Song J
Year: 2000
Journal: Cancer Res
Title: Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice.
Volume: 60
Issue: 12
Pages: 3191-9
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Publication
11245490 | J:68513
First Author: Oshima M
Year: 2001
Journal: Cancer Res
Title: Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.
Volume: 61
Issue: 4
Pages: 1733-40
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Publication
27425618 | J:238661
First Author: Sato S
Year: 2016
Journal: Cell Rep
Title: Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype.
Volume: 16
Issue: 4
Pages: 917-927
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Publication
34079124 | J:325755
First Author: Flanagan DJ
Year: 2021
Journal: Nature
Title: NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Volume: 594
Issue: 7863
Pages: 430-435
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Publication
26240067 | J:226570
First Author: Huels DJ
Year: 2015
Journal: EMBO J
Title: E-cadherin can limit the transforming properties of activating β-catenin mutations.
Volume: 34
Issue: 18
Pages: 2321-33
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Publication
28003334 | J:277034
First Author: Myant KB
Year: 2017
Journal: EMBO Mol Med
Title: HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Volume: 9
Issue: 2
Pages: 181-197
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Publication
37309673 | J:360727
First Author: Suzuki T
Year: 2023
Journal: Cancer Immunol Res
Title: β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer.
Volume: 11
Issue: 8
Pages: 1137-1155
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Publication
29340033 | J:256521
First Author: Sakitani K
Year: 2017
Journal: Oncotarget
Title: CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development.
Volume: 8
Issue: 67
Pages: 111012-111025
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Publication
23241743 | J:309199
First Author: Blatner NR
Year: 2012
Journal: Sci Transl Med
Title: Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.
Volume: 4
Issue: 164
Pages: 164ra159
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Publication
20084116 | J:156864
First Author: Buchert M
Year: 2010
Journal: PLoS Genet
Title: Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.
Volume: 6
Issue: 1
Pages: e1000816
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Publication
17062636 | J:117129
First Author: Suraweera N
Year: 2006
Journal: Hum Mol Genet
Title: Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.
Volume: 15
Issue: 23
Pages: 3429-35
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Publication
19356224 | J:149225
 
First Author: Miclea RL
Year: 2009
Journal: BMC Dev Biol
Title: Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors.
Volume: 9
Pages: 26
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Publication
21858154 | J:178127
First Author: Larriba MJ
Year: 2011
Journal: PLoS One
Title: Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer.
Volume: 6
Issue: 8
Pages: e23524
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Publication
26528816 | J:231703
First Author: Feng Y
Year: 2015
Journal: PLoS Genet
Title: Tissue-Specific Effects of Reduced β-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium.
Volume: 11
Issue: 11
Pages: e1005638
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Publication
26279473 | J:227728
First Author: Zhai Y
Year: 2016
Journal: J Pathol
Title: Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival.
Volume: 238
Issue: 1
Pages: 21-30
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Publication
17002498 | J:114152
First Author: Kuraguchi M
Year: 2006
Journal: PLoS Genet
Title: Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.
Volume: 2
Issue: 9
Pages: e146
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Publication
31965581 | J:339432
First Author: Bisso A
Year: 2020
Journal: Hepatology
Title: Cooperation Between MYC and β-Catenin in Liver Tumorigenesis Requires Yap/Taz.
Volume: 72
Issue: 4
Pages: 1430-1443
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Publication
26245956 | J:225880
First Author: Kraushar ML
Year: 2015
Journal: J Neurosci
Title: Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes.
Volume: 35
Issue: 31
Pages: 10911-26
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Publication
18038450 | J:243698
First Author: Decaens T
Year: 2008
Journal: Hepatology
Title: Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.
Volume: 47
Issue: 1
Pages: 247-58
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Publication
35673579 | J:325989
First Author: Park SY
Year: 2022
Journal: Theranostics
Title: Dysadherin awakens mechanical forces and promotes colorectal cancer progression.
Volume: 12
Issue: 9
Pages: 4399-4414
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Publication
19149881 | J:160733
 
First Author: Ivaniutsin U
Year: 2009
Journal: Neural Dev
Title: Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex.
Volume: 4
Pages: 3
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Protein Coding Gene
MGP_CAROLIEiJ_G0022085 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024036 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024151 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024064 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023188 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018819 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022997 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
24913681 | J:216876
First Author: Zeineldin M
Year: 2014
Journal: Genetics
Title: Human cancer xenografts in outbred nude mice can be confounded by polymorphisms in a modifier of tumorigenesis.
Volume: 197
Issue: 4
Pages: 1365-76
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Publication
15343335 | J:92659
First Author: Mazelin L
Year: 2004
Journal: Nature
Title: Netrin-1 controls colorectal tumorigenesis by regulating apoptosis.
Volume: 431
Issue: 7004
Pages: 80-4
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Publication
10733430 | J:60778
First Author: Peifer M
Year: 2000
Journal: Science
Title: Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus.
Volume: 287
Issue: 5458
Pages: 1606-9
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Publication
2296722 | J:10209
First Author: Moser AR
Year: 1990
Journal: Science
Title: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse.
Volume: 247
Issue: 4940
Pages: 322-4
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Publication
25592152 | J:219805
First Author: Bastide NM
Year: 2015
Journal: Cancer Res
Title: A central role for heme iron in colon carcinogenesis associated with red meat intake.
Volume: 75
Issue: 5
Pages: 870-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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