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Search results 701 to 800 out of 1013 for Braf

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Type Details Score
Publication
35672316 | J:325350
First Author: Murphy BM
Year: 2022
Journal: Nat Commun
Title: Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Volume: 13
Issue: 1
Pages: 3153
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Publication
29295999 | J:258475
First Author: Han S
Year: 2018
Journal: Nat Commun
Title: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.
Volume: 9
Issue: 1
Pages: 28
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Publication
29880484 | J:264050
First Author: Saei A
Year: 2018
Journal: J Exp Med
Title: Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.
Volume: 215
Issue: 7
Pages: 1913-1928
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HT Experiment
GSE235033 | Q241R mutation of Braf gene causes neurological abnormalities in a mouse model of cardio-facio-cutaneous syndrome independent of developmental malformations
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
19079609 | J:144358
First Author: Jeong JH
Year: 2008
Journal: PLoS One
Title: BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
Volume: 3
Issue: 12
Pages: e3949
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Allele
Braf<em2Smoc> | MGI:7288520
Name: Braf transforming gene; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28174173 | J:240401
First Author: Wan L
Year: 2017
Journal: Cancer Discov
Title: The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Volume: 7
Issue: 4
Pages: 424-441
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Publication
22693252 | J:189290
First Author: Koya RC
Year: 2012
Journal: Cancer Res
Title: BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.
Volume: 72
Issue: 16
Pages: 3928-37
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Publication
29540830 | J:263924
First Author: Dankner M
Year: 2018
Journal: Oncogene
Title: Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.
Volume: 37
Issue: 24
Pages: 3183-3199
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Publication
10051318 | J:53815
First Author: Vacher J
Year: 1999
Journal: Mamm Genome
Title: Genetic localization and transmission of the mouse osteopetrotic grey-lethal mutation.
Volume: 10
Issue: 3
Pages: 239-43
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Publication
8455932 | J:4634
First Author: Wadewitz AG
Year: 1993
Journal: Oncogene
Title: Developmental and cell lineage specificity of raf family gene expression in mouse testis.
Volume: 8
Issue: 4
Pages: 1055-62
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Publication
25843629 | J:222864
First Author: Karreth FA
Year: 2015
Journal: Cell
Title: The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Volume: 161
Issue: 2
Pages: 319-32
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Publication
24828987 | J:214390
First Author: Gandolfi G
Year: 2015
Journal: Int J Cancer
Title: Time to re-consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma.
Volume: 137
Issue: 5
Pages: 1001-11
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Publication
28404629 | J:242910
First Author: Lim CS
Year: 2017
Journal: Genes Dev
Title: BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method.
Volume: 31
Issue: 6
Pages: 537-552
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Publication
26541605 | J:299365
First Author: Yun J
Year: 2015
Journal: Science
Title: Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Volume: 350
Issue: 6266
Pages: 1391-6
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Publication
29433126 | -
First Author: Lavoie H
Year: 2018
Journal: Nature
Title: MEK drives BRAF activation through allosteric control of KSR proteins.
Volume: 554
Issue: 7693
Pages: 549-553
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Publication
25109331 | J:222531
First Author: Riemer P
Year: 2015
Journal: Oncogene
Title: Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity.
Volume: 34
Issue: 24
Pages: 3164-75
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Publication
26286024 | J:260644
First Author: Ramsdale R
Year: 2015
Journal: Sci Signal
Title: The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
Volume: 8
Issue: 390
Pages: ra82
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Publication
25351955 | J:218275
First Author: Ferrari de Andrade L
Year: 2014
Journal: Cancer Res
Title: Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma.
Volume: 74
Issue: 24
Pages: 7298-308
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Publication
22256804 | J:181162
First Author: Su F
Year: 2012
Journal: N Engl J Med
Title: RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
Volume: 366
Issue: 3
Pages: 207-15
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Publication
33206716 | J:297542
First Author: Younes ST
Year: 2020
Journal: PLoS One
Title: In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma.
Volume: 15
Issue: 11
Pages: e0242521
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Publication
39335105 | J:354602
 
First Author: Dorfer S
Year: 2024
Journal: Cancers (Basel)
Title: BRAF Inhibition and UVB Light Synergistically Promote Mus musculus Papillomavirus 1-Induced Skin Tumorigenesis.
Volume: 16
Issue: 18
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Strain
MGI:6354563 | C57BL/6JSmoc-Braf<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
24163374 | J:208914
First Author: Faber AC
Year: 2014
Journal: Cancer Discov
Title: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Volume: 4
Issue: 1
Pages: 42-52
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Publication
9799843 | J:50580
First Author: Wojnowski L
Year: 1998
Journal: Mamm Genome
Title: Reduced activity of BRAF protein kinase in hop and hop(hpy) mouse mutants.
Volume: 9
Issue: 11
Pages: 905-6
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Publication
17510423 | J:121738
First Author: Ji H
Year: 2007
Journal: Cancer Res
Title: Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.
Volume: 67
Issue: 10
Pages: 4933-9
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Publication
28827320 | J:250257
First Author: Duggan MC
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.
Volume: 114
Issue: 36
Pages: 9629-9634
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Publication
39774818 | J:361021
First Author: Moriya A
Year: 2025
Journal: Hum Mol Genet
Title: Q241R mutation of Braf causes neurological abnormalities in a mouse model of cardio-facio-cutaneous syndrome, independent of developmental malformations.
Volume: 34
Issue: 5
Pages: 418-434
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Allele
Braf<em1Smoc> | MGI:7288519
Name: Braf transforming gene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
26248136 | J:232891
First Author: Zhang ZX
Year: 2015
Journal: Biochem Biophys Res Commun
Title: BRAF activated non-coding RNA (BANCR) promoting gastric cancer cells proliferation via regulation of NF-κB1.
Volume: 465
Issue: 2
Pages: 225-31
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Publication
39137048 | J:354612
 
First Author: Tripathi S
Year: 2024
Journal: J Clin Invest
Title: Pediatric glioma immune profiling identifies TIM3 as a therapeutic target in BRAF fusion pilocytic astrocytoma.
Volume: 134
Issue: 19
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Strain
MGI:6770599 | C57BL/6JSmoc-Braf<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
18974108 | -
First Author: Jones DT
Year: 2008
Journal: Cancer Res
Title: Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas.
Volume: 68
Issue: 21
Pages: 8673-7
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Interaction Experiment
Chiappetta G (2012)
Description: BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein.
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Publication
28910386 | J:249827
First Author: Buffet C
Year: 2017
Journal: PLoS One
Title: DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers.
Volume: 12
Issue: 9
Pages: e0184861
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Allele
Braf<tm1Mmcm> | MGI:3711771
Name: Braf transforming gene; targeted mutation 1, Martin McMahon
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1.1Brum> | MGI:5912238
Name: Braf transforming gene; targeted mutation 1.1, Tilman Brummer
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Braf<tm1.2Brum> | MGI:5912240
 
Name: Braf transforming gene; targeted mutation 1.2, Tilman Brummer
Allele Type: Targeted
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Allele
Braf<tm2Mmcm> | MGI:7448917
Name: Braf transforming gene; targeted mutation 2, Martin McMahon
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, No functional change
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Allele
Braf<+> | MGI:1857578
 
Name: Braf transforming gene; wild type
Allele Type: Not Specified
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Allele
Braf<tm1Cpri> | MGI:3612533
Name: Braf transforming gene; targeted mutation 1, Catrin Pritchard
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, No functional change
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Publication
19363522 | -
First Author: Jones DT
Year: 2009
Journal: Oncogene
Title: Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
Volume: 28
Issue: 20
Pages: 2119-23
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DO Term
DOID:0060585 | Noonan syndrome 7
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DO Term
DOID:0111460 | cardiofaciocutaneous syndrome 1
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Strain
MGI:6474868 | C57BL/6JSmoc-Braf<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7491963 | STOCK Braf<tm2Mmcm>/J
Attribute String: mutant stock, targeted mutation
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Allele
Braf<Gt(XE282)Byg> | MGI:4124775
 
Name: Braf transforming gene; gene trap XE282, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(XE617)Byg> | MGI:4125983
 
Name: Braf transforming gene; gene trap XE617, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(XN124)Byg> | MGI:4129692
 
Name: Braf transforming gene; gene trap XN124, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(RRO367)Byg> | MGI:4329116
 
Name: Braf transforming gene; gene trap RRO367, BayGenomics
Allele Type: Gene trapped
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Allele
Braf<Gt(RRS254)Byg> | MGI:4330273
 
Name: Braf transforming gene; gene trap RRS254, BayGenomics
Allele Type: Gene trapped
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Strain
MGI:6792070 | STOCK Braf<tm1Mmcm>/Cvrk
Attribute String: mutant stock, targeted mutation
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Strain
MGI:5317166 | B6.129P2(Cg)-Braf<tm1Mmcm>/J
Attribute String: mutant strain, congenic, targeted mutation
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DO Term
DOID:0080550 | Noonan syndrome with multiple lentigines 3
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Publication
16753739 | -
First Author: Lee JH
Year: 2006
Journal: Pathology
Title: BRAF mutation and AKAP9 expression in sporadic papillary thyroid carcinomas.
Volume: 38
Issue: 3
Pages: 201-4
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Genotype
Genotype
Symbol: Braf/Braf
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Allele
Braf<tm1Zim> | MGI:1857579
Name: Braf transforming gene; targeted mutation 1, Andreas Zimmer
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf-rs1<+> | MGI:2430095
   
Name: Braf transforming gene, related sequence 1; wild type
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Allele
Braf<tm1Sva> | MGI:3620008
Name: Braf transforming gene; targeted mutation 1, Alcino J Silva
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1.1Sva> | MGI:3622462
Name: Braf transforming gene; targeted mutation 1.1, Alcino Silva
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<tm1(ARAF)Urr> | MGI:3664469
 
Name: Braf transforming gene; targeted mutation 1, Ulf R Rapp
Allele Type: Targeted
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Allele
Braf<tm1Wds> | MGI:3711006
Name: Braf transforming gene; targeted mutation 1, William D Snider
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1.1Wds> | MGI:3711007
Name: Braf transforming gene; targeted mutation 1.1, William D Snider
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<Gt(AY0605)Wtsi> | MGI:3857502
 
Name: Braf transforming gene; gene trap AY0605, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(AN0584)Wtsi> | MGI:3864100
 
Name: Braf transforming gene; gene trap AN0584, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(BA0436)Wtsi> | MGI:3864349
 
Name: Braf transforming gene; gene trap BA0436, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(CH0627)Wtsi> | MGI:3872006
 
Name: Braf transforming gene; gene trap CH0627, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(F045D02)Wrst> | MGI:4123655
 
Name: Braf transforming gene; gene trap F045D02, German Gene Trap Consortium
Allele Type: Gene trapped
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Allele
Braf<Gt(OST40239)Lex> | MGI:4156812
 
Name: Braf transforming gene; gene trap OST40239, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(OST60560)Lex> | MGI:4167460
 
Name: Braf transforming gene; gene trap OST60560, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(OST309428)Lex> | MGI:4274472
 
Name: Braf transforming gene; gene trap OST309428, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(OST364120)Lex> | MGI:4295037
 
Name: Braf transforming gene; gene trap OST364120, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(OST379833)Lex> | MGI:4300482
 
Name: Braf transforming gene; gene trap OST379833, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(OST436107)Lex> | MGI:4316537
 
Name: Braf transforming gene; gene trap OST436107, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Braf<Gt(AA0135)Wtsi> | MGI:4345318
 
Name: Braf transforming gene; gene trap AA0135, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(AT0126)Wtsi> | MGI:4346783
 
Name: Braf transforming gene; gene trap AT0126, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Braf<Gt(EUCE00111f02)Hmgu> | MGI:4382681
 
Name: Braf transforming gene; gene trap EUCE00111f02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<Gt(EUCE00115e08)Hmgu> | MGI:4395430
 
Name: Braf transforming gene; gene trap EUCE00115e08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<Gt(EUCE0154c11)Hmgu> | MGI:4396439
 
Name: Braf transforming gene; gene trap EUCE0154c11, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Braf<tm1Rima> | MGI:4458346
Name: Braf transforming gene; targeted mutation 1, Richard Marais
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm1a(EUCOMM)Wtsi> | MGI:4820236
Name: Braf transforming gene; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Braf<tm1e(EUCOMM)Wtsi> | MGI:4820369
Name: Braf transforming gene; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Braf<tm1.1Eyc> | MGI:4888303
Name: Braf transforming gene; targeted mutation 1.1, Alain Eychene
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Braf<tm2.1Eyc> | MGI:4888305
Name: Braf transforming gene; targeted mutation 2.1, Alain Eychene
Allele Type: Targeted
Attribute String: Modified isoform(s)
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Allele
Braf<tm1Bbd> | MGI:4946645
Name: Braf transforming gene; targeted mutation 1, Mariano Barbacid
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Hypomorph
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Allele
Braf<tm1Tuv> | MGI:5318063
Name: Braf transforming gene; targeted mutation 1, David A Tuveson
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm2Cpri> | MGI:5440045
Name: Braf transforming gene; targeted mutation 2, Catrin Pritchard
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm2Urr> | MGI:5512687
Name: Braf transforming gene; targeted mutation 2, Urr R Rapp
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm2.1Urr> | MGI:5512688
Name: Braf transforming gene; targeted mutation 2.1, Urr R Rapp
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Braf<tm2.2Urr> | MGI:5512689
Name: Braf transforming gene; targeted mutation 2.2, Urr R Rapp
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Braf<tm1.1Brd> | MGI:5527388
Name: Braf transforming gene; targeted mutation 1.1, Allan Bradley
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Braf<tm1Tumg> | MGI:5902220
Name: Braf transforming gene; targeted mutation 1, Yoko Aoki
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Braf<em1Gpt> | MGI:7295988
Name: Braf transforming gene; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Braf<em6Gpt> | MGI:7295989
Name: Braf transforming gene; endonuclease-mediated mutation 6, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Braf<tm1.1Tumg> | MGI:7488140
 
Name: Braf transforming gene; targeted mutation 1.1, Yoko Aoki
Allele Type: Targeted
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Allele
Braf<em1Cya> | MGI:7582620
Name: Braf transforming gene; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Braf<em2Cya> | MGI:7582621
Name: Braf transforming gene; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Braf/Braf<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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