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Search results 701 to 800 out of 1008 for Cd36

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Type Details Score
Allele
Cd36<em5Cya> | MGI:7792579
Name: CD36 molecule; endonuclease-mediated mutation 5, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd36<em6Cya> | MGI:7792580
Name: CD36 molecule; endonuclease-mediated mutation 6, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
14752028 | J:97594
First Author: Ishii T
Year: 2004
Journal: Circ Res
Title: Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.
Volume: 94
Issue: 5
Pages: 609-16
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Publication
22773661 | J:189761
First Author: Guo L
Year: 2012
Journal: J Immunol
Title: Comment on "Class B scavenger receptor types I and II and CD36 targeting improves sepsis survival and acute outcomes in mice".
Volume: 189
Issue: 2
Pages: 501; author reply 502
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Strain
MGI:4888396 | B6.129S1-Cd36<tm1Mfe>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:5433737 | B6.129S1-Cd36<tm1Mfe>/J
Attribute String: congenic, mutant strain, targeted mutation
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Allele
Cd36<tm1Frm> | MGI:2447190
Name: CD36 molecule; targeted mutation 1, Mason W Freeman
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd36<tm1(NCOM)Mfgc> | MGI:4880454
Name: CD36 molecule; targeted mutation 1, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd36<tm1a(EUCOMM)Wtsi> | MGI:4944546
Name: CD36 molecule; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd36<tm1.1Ijg> | MGI:6194992
Name: CD36 molecule; targeted mutation 1.1, Ira J Goldberg
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Cd36<em1(IMPC)Mbp> | MGI:6276959
Name: CD36 molecule; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd36<em11Gpt> | MGI:7296577
Name: CD36 molecule; endonuclease-mediated mutation 11, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd36<em1Gpt> | MGI:7296578
Name: CD36 molecule; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7577285 | C57BL/6JGpt-Cd36<em2(CD36)Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7593009 | C57BL/6J-Cd36<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7588169 | C57BL/6J-Cd36<em3Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7838322 | C57BL/6N-Cd36<em4Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7834611 | C57BL/6N-Cd36<em5Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7835155 | C57BL/6N-Cd36<em6Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: B6.129S1-Cd36
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: involves: 129S1/Sv
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
E-GEOD-39585 | Decrease of Parkin and CD36 expression and body weight correlate with an increase of non-esterified fatty acids in a mouse model for TDP-43 pathology
Series Id: GSE39585
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Coding Gene
MGI:1196458 | Scarb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32801299 | -
First Author: Xia X
Year: 2020
Journal: Cell Death Dis
Title: Deubiquitination of CD36 by UCHL1 promotes foam cell formation.
Volume: 11
Issue: 8
Pages: 636
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Strain
MGI:4453139 | B6.129S4-Cd36<tm1Frm>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6194993 | STOCK Cd36<tm1.1Ijg>/J
Attribute String: mutant stock, targeted mutation
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Strain
MGI:6347855 | C57BL/6NCrl-Cd36<em1(IMPC)Mbp>/Mmucd
Attribute String: mutant strain, coisogenic, endonuclease-mediated mutation
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Strain
MGI:6696535 | C57BL/6N-Cd36<em1(IMPC)Mbp>/MbpMmucd
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6424710 | C57BL/6JGpt-Cd36<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: B6.129S4-Cd36
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd36/Cd36
Background: C57BL/6N-Cd36/MbpMmucd
Zygosity: hm
Has Mutant Allele: true
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Publication
16020694 | -
First Author: Philips JA
Year: 2005
Journal: Science
Title: Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection.
Volume: 309
Issue: 5738
Pages: 1251-3
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Publication
18353783 | -
First Author: Smith J
Year: 2008
Journal: J Biol Chem
Title: Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on fatty acid uptake.
Volume: 283
Issue: 20
Pages: 13578-85
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Allele
Tg(Ckm-Cd36)1Naa | MGI:3652419
Name: transgene insertion 1, Nada A Abumrad
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5755141 | B6.Cg-Cd36<tm2.1Mfe> A1cf<Tg(Myh6-cre/Esr1*)1Jmk>
Attribute String: mutant strain, targeted mutation, transgenic, congenic
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Genotype
Genotype
Symbol: Apoe/Apoe Cd36/Cd36
Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
22022213 | -
First Author: Krammer J
Year: 2011
Journal: Int J Med Sci
Title: Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells.
Volume: 8
Issue: 7
Pages: 599-614
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Genotype
Genotype
Symbol: Tg(Ckm-Cd36)1Naa/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd36/Cd36 A1cf/A1cf<+>
Background: B6.Cg-Cd36 A1cf
Zygosity: cn
Has Mutant Allele: true
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Publication
18653762 | -
First Author: Jin X
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: SNMP is a signaling component required for pheromone sensitivity in Drosophila.
Volume: 105
Issue: 31
Pages: 10996-1001
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Publication
9291126 | -
 
First Author: Fluiter K
Year: 1997
Journal: Biochem J
Title: Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells.
Volume: 326 ( Pt 2)
Pages: 515-9
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Publication
21489334 | -
 
First Author: Dao Thi VL
Year: 2011
Journal: Expert Rev Mol Med
Title: Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation.
Volume: 13
Pages: e13
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Protein Domain
IPR005428 | CD36/SCARB1/SNMP1
Type: Family
Description: This entry includes platelet glycoprotein 4 (CD36) and scavenger receptor class B member 1 (SCARB1, also known as CD36 antigen-like 1) from humans, and sensory neuron membrane protein 1 (SNMP1) from flies. CD36 is a a scavenger receptor important for lipoprotein binding and uptake of cholesterol and lipids in vertebrates []. SCARB1 plays an important role in the uptake of HDL cholesteryl ester []. It acts as a receptor for hepatitis C virus in hepatocytes [].SNMP1 is a homologue of CD36. SNMP1 has a role in detection and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA) [].
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Publication
1715871 | -
First Author: Vega MA
Year: 1991
Journal: J Biol Chem
Title: Cloning, sequencing, and expression of a cDNA encoding rat LIMP II, a novel 74-kDa lysosomal membrane protein related to the surface adhesion protein CD36.
Volume: 266
Issue: 25
Pages: 16818-24
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Protein Domain
IPR005429 | LimpII
Type: Family
Description: Lysosome membrane protein II (LIMP II) is a 478-residue glycoproteinexpressed in the membrane of lysosomes and secretory granules with lysosomalproperties []. The N-terminal segment (residues ~4-26) constitutes an uncleavable signal peptide []. LIMP II possesses an additional C-terminalhydrophobic region that, together with the signal peptide, may anchor theprotein to the membrane []. The major portion of the protein resides ontheluminal side and contains 11 potential N-glycosylation sites and 5 cysteineresidues. The N- and C-terminal ends of the protein constitute short cytoplasmic tails. LIMP II is a subgroup of a larger family of the cell surface protein CD36 involved in cell adhesion.
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HT Experiment
GSE174384 | Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE254704 | Skeletal muscle cystathionine -lyase deficiency promotes obesity and insulin resistance and results in hyperglycemia and skeletal muscle injury upon HFD in mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
19830595 | -
First Author: Tan K
Year: 2009
Journal: J Cell Commun Signal
Title: The interaction of Thrombospondins with extracellular matrix proteins.
Volume: 3
Issue: 3-4
Pages: 177-87
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Publication
9657149 | J:48446
First Author: Crawford SE
Year: 1998
Journal: Cell
Title: Thrombospondin-1 is a major activator of TGF-beta1 in vivo.
Volume: 93
Issue: 7
Pages: 1159-70
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Publication
21765615 | -
 
First Author: Lopez-Dee Z
Year: 2011
Journal: Mediators Inflamm
Title: Thrombospondin-1: multiple paths to inflammation.
Volume: 2011
Pages: 296069
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Protein Domain
IPR028499 | Thrombospondin-1
Type: Family
Description: Thrombospondin 1 (TSP-1) is a member of the thrombospondin (TSP) family, which consists of five extracellular calcium-binding multifunctional proteins: TSP-1, TSP-2, TSP-3, TSP-4, and TSP-5. TSP-1 is involved in angiogenesis, cancer, and inflammation. It is a major activator of transforming growth factor (TGFbeta1), which mediates wound healing, cell proliferation, extracellular matrix formation, and the immune response [].TSP-1 is a large, homotrimeric molecule. Each monomer consists of an N-terminal globular domain that binds heparin, type I, type II, and type III repeats, and a C-terminal globular domain. All five members of the TSP family have the repeat domains type II and III, but only TSP-1 and TSP-2 contain the type I repeats []. TSP-1-specific domains bind to proteoglycans, membrane proteins such as integrins, and other matrix proteins expressed by a variety of cells [, ]. Type I repeats, also called thrombospondin structural homology repeats (TSRs), inhibit angiogenesis by activating CD36 and inducing apoptosis in endothelial cells [].
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HT Experiment
GSE237040 | Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
20659467 | J:163621
First Author: Gan L
Year: 2010
Journal: FEBS Lett
Title: Transcription factor activator protein-2beta accelerates lipid accumulation in macrophages via enhancing the transcription of CD36.
Volume: 584
Issue: 16
Pages: 3615-9
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Publication
38963761 | J:360212
First Author: Sciarretta F
Year: 2024
Journal: Cell Rep
Title: Lipid-associated macrophages reshape BAT cell identity in obesity.
Volume: 43
Issue: 7
Pages: 114447
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Publication
30683852 | J:271289
First Author: Fan J
Year: 2019
Journal: Nat Commun
Title: CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ.
Volume: 10
Issue: 1
Pages: 425
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Publication
29802249 | J:262938
First Author: Misra A
Year: 2018
Journal: Nat Commun
Title: Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells.
Volume: 9
Issue: 1
Pages: 2073
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Publication
37332345 | J:346946
 
First Author: Gauvin J
Year: 2023
Journal: Front Pharmacol
Title: A cyclic azapeptide ligand of the scavenger receptor CD36/SR-B2 reduces the atherosclerotic lesion progression and enhances plaque stability in apolipoprotein E-deficient mice.
Volume: 14
Pages: 1204905
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Publication
25801026 | J:228174
First Author: Oh J
Year: 2015
Journal: Cell Rep
Title: Deletion of macrophage Vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice.
Volume: 10
Issue: 11
Pages: 1872-86
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Publication
10953027 | J:64040
First Author: Li AC
Year: 2000
Journal: J Clin Invest
Title: Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice.
Volume: 106
Issue: 4
Pages: 523-31
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Publication
27460411 | J:241166
 
First Author: Aryal B
Year: 2016
Journal: Nat Commun
Title: ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Volume: 7
Pages: 12313
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Publication
10866668 | J:63040
First Author: Peters JM
Year: 2000
Journal: Mol Cell Biol
Title: Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta).
Volume: 20
Issue: 14
Pages: 5119-28
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Publication
32532986 | J:292186
First Author: Bae H
Year: 2020
Journal: Nat Commun
Title: Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance.
Volume: 11
Issue: 1
Pages: 2980
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Publication
30989113 | J:287672
First Author: Chen Q
Year: 2019
Journal: Sci Adv
Title: Targeting RalGAPα1 in skeletal muscle to simultaneously improve postprandial glucose and lipid control.
Volume: 5
Issue: 4
Pages: eaav4116
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Publication
39317200 | J:359351
First Author: Guo W
Year: 2024
Journal: Immunity
Title: Notch signaling regulates macrophage-mediated inflammation in metabolic dysfunction-associated steatotic liver disease.
Volume: 57
Issue: 10
Pages: 2310-2327.e6
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Publication
23378601 | J:195158
First Author: Takahashi M
Year: 2013
Journal: J Lipid Res
Title: Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity.
Volume: 54
Issue: 4
Pages: 1124-34
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Publication
38594269 | J:359878
First Author: Tang W
Year: 2024
Journal: Nat Commun
Title: LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments.
Volume: 15
Issue: 1
Pages: 3068
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Publication
16105663 | J:100642
First Author: Zhou H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Gastric inhibitory polypeptide modulates adiposity and fat oxidation under diminished insulin action.
Volume: 335
Issue: 3
Pages: 937-42
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Publication
24441829 | J:206863
First Author: Khalifeh-Soltani A
Year: 2014
Journal: Nat Med
Title: Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids.
Volume: 20
Issue: 2
Pages: 175-83
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Publication
28919867 | J:247528
 
First Author: Demenis C
Year: 2017
Journal: Front Physiol
Title: Sulfated Cholecystokinin-8 Promotes CD36-Mediated Fatty Acid Uptake into Primary Mouse Duodenal Enterocytes.
Volume: 8
Pages: 660
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Publication
28511797 | J:250747
First Author: Ji Q
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Deficiency of liver-X-receptor-α reduces glucose uptake and worsens post-myocardial infarction remodeling.
Volume: 488
Issue: 3
Pages: 489-495
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Publication
33087562 | J:297118
First Author: Yang PB
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.
Volume: 117
Issue: 44
Pages: 27412-27422
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Publication
11423995 | J:124515
First Author: Jiménez B
Year: 2001
Journal: Oncogene
Title: c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1.
Volume: 20
Issue: 26
Pages: 3443-8
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Publication
30850475 | J:274376
First Author: Helou DG
Year: 2019
Journal: J Immunol
Title: Cutting Edge: Nrf2 Regulates Neutrophil Recruitment and Accumulation in Skin during Contact Hypersensitivity.
Volume: 202
Issue: 8
Pages: 2189-2194
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Publication
31604271 | J:279217
First Author: Kuang Z
Year: 2019
Journal: Science
Title: The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3.
Volume: 365
Issue: 6460
Pages: 1428-1434
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Publication
24012002 | J:201742
First Author: Lucin KM
Year: 2013
Journal: Neuron
Title: Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease.
Volume: 79
Issue: 5
Pages: 873-86
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Publication
23689639 | J:207253
 
First Author: Xia F
Year: 2013
Journal: Sci Rep
Title: IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis.
Volume: 3
Pages: 1867
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Publication
36344546 | J:337613
First Author: Brailey PM
Year: 2022
Journal: Nat Commun
Title: CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses.
Volume: 13
Issue: 1
Pages: 6723
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Publication
33017390 | J:296948
First Author: Xu J
Year: 2020
Journal: PLoS Biol
Title: Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Volume: 18
Issue: 10
Pages: e3000837
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Publication
22528465 | J:192688
First Author: Huang J
Year: 2012
Journal: Transgenic Res
Title: Ectopic overexpression of swine PPARγ2 upregulated adipocyte genes expression and triacylglycerol in skeletal muscle of mice.
Volume: 21
Issue: 6
Pages: 1311-8
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Publication
35927268 | J:330788
First Author: Li X
Year: 2022
Journal: Nat Commun
Title: Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Volume: 13
Issue: 1
Pages: 4549
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Publication
12439745 | J:80294
First Author: Hawighorst T
Year: 2002
Journal: Oncogene
Title: Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice.
Volume: 21
Issue: 52
Pages: 7945-56
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Publication
26853749 | J:233031
First Author: Schlein C
Year: 2016
Journal: Cell Metab
Title: FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues.
Volume: 23
Issue: 3
Pages: 441-53
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Publication
28205579 | J:275074
 
First Author: Wang Z
Year: 2017
Journal: Sci Rep
Title: Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2.
Volume: 7
Pages: 42095
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Publication
32640240 | J:301619
First Author: Valet C
Year: 2020
Journal: Cell Rep
Title: Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation.
Volume: 32
Issue: 1
Pages: 107875
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Publication
36184646 | J:330566
First Author: Yang P
Year: 2022
Journal: Nat Commun
Title: CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis.
Volume: 13
Issue: 1
Pages: 5782
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Publication
36465125 | J:332006
First Author: Liu J
Year: 2022
Journal: iScience
Title: Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke.
Volume: 25
Issue: 12
Pages: 105527
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Publication
38316788 | J:345059
First Author: Dawson A
Year: 2024
Journal: Nat Commun
Title: Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche.
Volume: 15
Issue: 1
Pages: 1090
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Publication
10432118 | J:200339
First Author: Huang JT
Year: 1999
Journal: Nature
Title: Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase.
Volume: 400
Issue: 6742
Pages: 378-82
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Publication
25561514 | J:234139
First Author: Coppiello G
Year: 2015
Journal: Circulation
Title: Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake.
Volume: 131
Issue: 9
Pages: 815-26
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Publication
24769669 | J:216627
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