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Search results 701 to 800 out of 841 for Cebpb

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Type Details Score
Allele
Name: CCAAT/enhancer binding protein beta; targeted mutation 1.1, Mohamed Elgazzar
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Ribeiro AC
Year: 2011
Journal: PLoS One
Title: Contrasting effects of leptin on food anticipatory and total locomotor activity.
Volume: 6
Issue: 8
Pages: e23364
Publication
First Author: Cairo S
Year: 2008
Journal: Cancer Cell
Title: Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer.
Volume: 14
Issue: 6
Pages: 471-84
Publication
First Author: Shachaf CM
Year: 2004
Journal: Nature
Title: MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.
Volume: 431
Issue: 7012
Pages: 1112-7
Publication
First Author: Hu S
Year: 2011
Journal: Cell Metab
Title: 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression.
Volume: 14
Issue: 1
Pages: 131-42
Publication
First Author: Beer S
Year: 2008
Journal: PLoS One
Title: Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis.
Volume: 3
Issue: 6
Pages: e2493
Publication
First Author: Kress TR
Year: 2016
Journal: Cancer Res
Title: Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.
Volume: 76
Issue: 12
Pages: 3463-72
Publication
First Author: Cao Z
Year: 2011
Journal: Cancer Res
Title: MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase.
Volume: 71
Issue: 6
Pages: 2286-97
Publication
First Author: Dolezal JM
Year: 2017
Journal: J Biol Chem
Title: Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma.
Volume: 292
Issue: 24
Pages: 10068-10086
Publication
First Author: Dhanasekaran R
Year: 2023
Journal: Cancer Res
Title: MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages.
Volume: 83
Issue: 4
Pages: 626-640
Publication
First Author: Chow EK
Year: 2011
Journal: Sci Transl Med
Title: Nanodiamond therapeutic delivery agents mediate enhanced chemoresistant tumor treatment.
Volume: 3
Issue: 73
Pages: 73ra21
Publication
First Author: Anderton B
Year: 2017
Journal: EMBO Rep
Title: MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.
Volume: 18
Issue: 4
Pages: 569-585
Publication
First Author: Kota J
Year: 2009
Journal: Cell
Title: Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model.
Volume: 137
Issue: 6
Pages: 1005-17
Publication
First Author: Dhanasekaran R
Year: 2018
Journal: Oncotarget
Title: Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC).
Volume: 9
Issue: 5
Pages: 5517-5528
Publication
First Author: Roy CN
Year: 2007
Journal: Blood
Title: Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation.
Volume: 109
Issue: 9
Pages: 4038-44
Strain
Attribute String: targeted mutation, transgenic, mutant strain, congenic
Strain
Attribute String: targeted mutation, mutant strain, coisogenic
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Makoto Miyazaki
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
Genotype
Symbol: Tg(tetO-MYC)36aBop/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)5Bjd/?
Background: involves: 129S4/SvJae * C57BL/6 * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)5Bjd/?
Background: involves: 129S4/SvJae * C57BL/6 * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)#Bjd/?
Background: B6.Cg-Col1a1 Tg(Cebpb-tTA)#Bjd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1 Tg(Cebpb-tTA)#Bjd/?
Background: B6.Cg-Col1a1 Tg(Cebpb-tTA)#Bjd
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Hendricks-Taylor LR
Year: 1992
Journal: Genomics
Title: The CCAAT/enhancer binding protein (C/EBP alpha) gene (CEBPA) maps to human chromosome 19q13.1 and the related nuclear factor NF-IL6 (C/EBP beta) gene (CEBPB) maps to human chromosome 20q13.1.
Volume: 14
Issue: 1
Pages: 12-7
Allele
Name: CCAAT/enhancer binding protein alpha; targeted mutation 1.1, Ying-Hue Lee
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Publication  
First Author: Grunewald M
Year: 2021
Journal: Science
Title: Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span.
Volume: 373
Issue: 6554
Publication
First Author: Saddic LA
Year: 2011
Journal: PLoS One
Title: Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.
Volume: 6
Issue: 5
Pages: e19758
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Wang R
Year: 2001
Journal: J Cell Biol
Title: Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice.
Volume: 153
Issue: 5
Pages: 1023-34
Publication
First Author: Ivanovska I
Year: 2011
Journal: PLoS One
Title: Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma.
Volume: 6
Issue: 9
Pages: e24582
Publication
First Author: Tward AD
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Distinct pathways of genomic progression to benign and malignant tumors of the liver.
Volume: 104
Issue: 37
Pages: 14771-6
Publication
First Author: Thomann S
Year: 2020
Journal: Cancer Res
Title: YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis.
Volume: 80
Issue: 24
Pages: 5502-5514
Publication  
First Author: Bitton-Worms K
Year: 2010
Journal: Mol Cancer
Title: The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice.
Volume: 9
Pages: 54
Strain
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Tg(tetO-MET)23Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Rb1/Rb1 Tg(tetO-MYC)36aBop/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: FVB/N * NMRI
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)5Bjd/?
Background: involves: 129S4/SvJae * C57BL/6 * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cebpb/Cebpb Lyz2/Lyz2<+>
Background: BALB/cJ-Cebpb Lyz2/Elgaz
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Cebpb-tTA)5Bjd/? Tg(tetO-MYC,-OVAL)#Gtgm/?
Background: B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm
Zygosity: cx
Has Mutant Allele: true
HT Experiment
Series Id: GSE15315
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Ma C
Year: 2016
Journal: Nature
Title: NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
Volume: 531
Issue: 7593
Pages: 253-7
Publication
First Author: Beer S
Year: 2004
Journal: PLoS Biol
Title: Developmental context determines latency of MYC-induced tumorigenesis.
Volume: 2
Issue: 11
Pages: e332
Publication
First Author: Cheung C
Year: 2004
Journal: Cancer Res
Title: Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha.
Volume: 64
Issue: 11
Pages: 3849-54
Publication
First Author: Foreman JE
Year: 2009
Journal: Toxicol Sci
Title: Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.
Volume: 110
Issue: 1
Pages: 204-11
Publication
First Author: Foreman JE
Year: 2021
Journal: Toxicol Sci
Title: Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice.
Volume: 183
Issue: 1
Pages: 70-80
Publication
First Author: Goga A
Year: 2007
Journal: Nat Med
Title: Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC.
Volume: 13
Issue: 7
Pages: 820-7
Publication
First Author: Xiang Y
Year: 2015
Journal: J Clin Invest
Title: Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Volume: 125
Issue: 6
Pages: 2293-306
Publication  
First Author: Schmidt AV
Year: 2023
Journal: Int J Mol Sci
Title: A Novel Transgenic Mouse Model Implicates Sirt2 as a Promoter of Hepatocellular Carcinoma.
Volume: 24
Issue: 16
Publication
First Author: Kornmann B
Year: 2007
Journal: PLoS Biol
Title: System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.
Volume: 5
Issue: 2
Pages: e34
Publication    
First Author: Dhanasekaran R
Year: 2020
Journal: Elife
Title: MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity.
Volume: 9
Genotype
Symbol: Cebpa/Cebpa
Background: involves: 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(tetO-Kdr*)4377.5Rwng/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: FVB/N * NMRI
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)#Bjd/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Greco CM
Year: 2021
Journal: Sci Adv
Title: Integration of feeding behavior by the liver circadian clock reveals network dependency of metabolic rhythms.
Volume: 7
Issue: 39
Pages: eabi7828
Publication
First Author: Itoh-Nakadai A
Year: 2017
Journal: Cell Rep
Title: A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.
Volume: 18
Issue: 10
Pages: 2401-2414
Publication
First Author: Jaitin DA
Year: 2016
Journal: Cell
Title: Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
Volume: 167
Issue: 7
Pages: 1883-1896.e15
Publication
First Author: Bahrami-Nejad Z
Year: 2018
Journal: Cell Metab
Title: A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation.
Volume: 27
Issue: 4
Pages: 854-868.e8
Publication
First Author: Sun Y
Year: 2006
Journal: J Lipid Res
Title: Conditional expression of human acid beta-glucosidase improves the visceral phenotype in a Gaucher disease mouse model.
Volume: 47
Issue: 10
Pages: 2161-70
Publication
First Author: Tao GZ
Year: 2013
Journal: J Biol Chem
Title: Wnt/β-catenin signaling protects mouse liver against oxidative stress-induced apoptosis through the inhibition of forkhead transcription factor FoxO3.
Volume: 288
Issue: 24
Pages: 17214-24
Publication
First Author: Gomes AL
Year: 2016
Journal: Cancer Cell
Title: Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma.
Volume: 30
Issue: 1
Pages: 161-175
Publication  
First Author: He J
Year: 2019
Journal: Cancer Lett
Title: Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma.
Volume: 458
Pages: 113-122
Publication
First Author: Bakiri L
Year: 2017
Journal: J Exp Med
Title: Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.
Volume: 214
Issue: 5
Pages: 1387-1409
Publication
First Author: Camargo FD
Year: 2007
Journal: Curr Biol
Title: YAP1 increases organ size and expands undifferentiated progenitor cells.
Volume: 17
Issue: 23
Pages: 2054-60
Publication
First Author: Gupta A
Year: 2008
Journal: Prostate
Title: Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.
Volume: 68
Issue: 1
Pages: 50-60
Publication
First Author: Suresh S
Year: 2017
Journal: PLoS Genet
Title: SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.
Volume: 13
Issue: 3
Pages: e1006650
Publication
First Author: Gouw AM
Year: 2019
Journal: Cell Metab
Title: The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth.
Volume: 30
Issue: 3
Pages: 556-572.e5
Publication
First Author: Croci O
Year: 2017
Journal: Genes Dev
Title: Transcriptional integration of mitogenic and mechanical signals by Myc and YAP.
Volume: 31
Issue: 20
Pages: 2017-2022
Publication  
First Author: Xie Y
Year: 2020
Journal: Endocrinology
Title: Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury.
Volume: 161
Issue: 1
Publication  
First Author: Chai X
Year: 2015
Journal: Nat Commun
Title: Oestrogen sulfotransferase ablation sensitizes mice to sepsis.
Volume: 6
Pages: 7979
Publication
First Author: Silva Barbosa AC
Year: 2020
Journal: J Am Soc Nephrol
Title: Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice.
Volume: 31
Issue: 7
Pages: 1496-1508
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Publication
First Author: Burén S
Year: 2016
Journal: Cancer Cell
Title: Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms.
Volume: 30
Issue: 2
Pages: 290-307
Genotype
Symbol: Cebpa/Cebpa
Background: involves: 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Col1a1/Col1a1<+> Tg(Cebpb-tTA)#Bjd/? Trp53/Trp53<+>
Background: B6.Cg-Trp53 Col1a1 Tg(Cebpb-tTA)#Bjd
Zygosity: cx
Has Mutant Allele: true
Publication  
First Author: Minogue PJ
Year: 2019
Journal: Mol Vis
Title: CHOP is dispensable for lens transparency in wild-type and connexin50 mutant mice.
Volume: 25
Pages: 535-545
Publication
First Author: de Paula GSM
Year: 2019
Journal: J Mol Endocrinol
Title: Neuromedin B receptor disruption impairs adipogenesis in mice and 3T3-L1 cells.
Volume: 63
Issue: 1
Pages: 93-102
Publication
First Author: Kurata M
Year: 2021
Journal: Cancer Sci
Title: C/EBPβ induces B-cell acute lymphoblastic leukemia and cooperates with BLNK mutations.
Volume: 112
Issue: 12
Pages: 4920-4930
Publication  
First Author: Bechara R
Year: 2021
Journal: Sci Immunol
Title: The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis.
Volume: 6
Issue: 61
Publication
First Author: Antonini D
Year: 2015
Journal: Nucleic Acids Res
Title: A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms.
Volume: 43
Issue: 2
Pages: 862-74
Publication
First Author: Salotti J
Year: 2015
Journal: Mol Cell Biol
Title: An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.
Volume: 35
Issue: 5
Pages: 866-83
Publication
First Author: Zhang N
Year: 2024
Journal: Exp Cell Res
Title: Exosomal long non-coding RNA AU020206 alleviates macrophage pyroptosis in atherosclerosis by suppressing CEBPB-mediated NLRP3 transcription.
Volume: 438
Issue: 2
Pages: 114054
Publication
First Author: Basu SK
Year: 2018
Journal: Cancer Res
Title: Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets.
Volume: 78
Issue: 4
Pages: 891-908
Publication  
First Author: Desouza LA
Year: 2021
Journal: Front Mol Neurosci
Title: The Hallucinogenic Serotonin2A Receptor Agonist, 2,5-Dimethoxy-4-Iodoamphetamine, Promotes cAMP Response Element Binding Protein-Dependent Gene Expression of Specific Plasticity-Associated Genes in the Rodent Neocortex.
Volume: 14
Pages: 790213
Publication
First Author: Clementi C
Year: 2013
Journal: PLoS Genet
Title: Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans.
Volume: 9
Issue: 11
Pages: e1003863
Publication
First Author: Qie C
Year: 2020
Journal: Theranostics
Title: Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis.
Volume: 10
Issue: 23
Pages: 10483-10497
Publication
First Author: Tummala KS
Year: 2014
Journal: Cancer Cell
Title: Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
Volume: 26
Issue: 6
Pages: 826-839
Publication
First Author: Ueberham E
Year: 2015
Journal: Mol Cancer Res
Title: Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a-negative tumors.
Volume: 13
Issue: 2
Pages: 239-49
Publication
First Author: Avraham-Davidi I
Year: 2013
Journal: J Exp Med
Title: On-site education of VEGF-recruited monocytes improves their performance as angiogenic and arteriogenic accessory cells.
Volume: 210
Issue: 12
Pages: 2611-25
Publication
First Author: Hsu SH
Year: 2012
Journal: J Clin Invest
Title: Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.
Volume: 122
Issue: 8
Pages: 2871-83
Publication
First Author: Hasan MT
Year: 2001
Journal: Genesis
Title: Long-term, noninvasive imaging of regulated gene expression in living mice.
Volume: 29
Issue: 3
Pages: 116-22
Publication
First Author: Dickins RA
Year: 2007
Journal: Nat Genet
Title: Tissue-specific and reversible RNA interference in transgenic mice.
Volume: 39
Issue: 7
Pages: 914-21
Publication
First Author: Nguyen LH
Year: 2014
Journal: Cancer Cell
Title: Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models.
Volume: 26
Issue: 2
Pages: 248-61
Publication
First Author: Kistner A
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.
Volume: 93
Issue: 20
Pages: 10933-8
Strain
Attribute String: transgenic, targeted mutation, mutant stock
Publication  
First Author: S Sonnet D
Year: 2016
Journal: Sci Rep
Title: Metformin inhibits Branched Chain Amino Acid (BCAA) derived ketoacidosis and promotes metabolic homeostasis in MSUD.
Volume: 6
Pages: 28775
Publication
First Author: Skvorak KJ
Year: 2009
Journal: Biochim Biophys Acta
Title: Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD).
Volume: 1792
Issue: 10
Pages: 1004-10
Genotype
Symbol: Dbt/Dbt Tg(tetO-DBT)A1Geh/? Tg(Cebpb-tTA)5Bjd/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
Zygosity: cx
Has Mutant Allele: true