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Search results 701 to 777 out of 777 for Cryaa

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Type Details Score
Publication
24270425 | J:207830
First Author: Sellitto C
Year: 2013
Journal: J Clin Invest
Title: AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development.
Volume: 123
Issue: 12
Pages: 5401-9
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Publication
33389129 | J:319410
First Author: Ali M
Year: 2021
Journal: Hum Genet
Title: A missense allele of PEX5 is responsible for the defective import of PTS2 cargo proteins into peroxisomes.
Volume: 140
Issue: 4
Pages: 649-666
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Publication
32173580 | J:298034
 
First Author: Shihan MH
Year: 2020
Journal: Matrix Biol
Title: Fibronectin has multifunctional roles in posterior capsular opacification (PCO).
Volume: 90
Pages: 79-108
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Publication
27304846 | J:257615
First Author: Sellitto C
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth.
Volume: 57
Issue: 7
Pages: 3145-51
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Publication
28951044 | J:287904
 
First Author: Whitson JA
Year: 2017
Journal: Free Radic Biol Med
Title: Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins.
Volume: 113
Pages: 84-96
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Publication
28525556 | J:242122
First Author: Whitson JA
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis.
Volume: 58
Issue: 5
Pages: 2666-2684
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Publication
28827139 | J:250101
First Author: Wei Z
Year: 2017
Journal: Am J Pathol
Title: Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin-Mediated Pathway: Relevance for Cataract Therapy.
Volume: 187
Issue: 11
Pages: 2399-2412
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Publication
24142921 | J:218363
First Author: Wolf L
Year: 2013
Journal: G3 (Bethesda)
Title: Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.
Volume: 3
Issue: 12
Pages: 2239-55
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Publication
27472077 | J:286662
First Author: Whitson JA
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis.
Volume: 57
Issue: 8
Pages: 3914-25
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Publication
38391903 | J:345586
 
First Author: Wazin F
Year: 2024
Journal: Cells
Title: Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth.
Volume: 13
Issue: 4
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Strain
MGI:4360335 | FVB-Tg(Cryaa-TAg,Ins2-CALM1)26Ove Tg(Myh6-SOD2,Tyr)3Pne
Attribute String: transgenic, mutant strain, coisogenic
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Publication
16317135 | J:106815
First Author: Mantena SK
Year: 2005
Journal: J Nutr
Title: Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumors.
Volume: 135
Issue: 12
Pages: 2871-7
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Genotype
Genotype
Symbol: Galk1/Galk1 Tg(Cryaa-AKR1B1)222Smch/?
Background: involves: 129S6/SvEvTac * C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Galk1/Galk1 Tg(Cryaa-AKR1B1)648Smch/?
Background: involves: 129S6/SvEvTac * C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Cryaa-cre,Tyr)39Mlr/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Cryaa-TAg,Ins2-CALM1)26Ove/? Tg(Myh6-SOD2,Tyr)3Pne/?
Background: FVB-Tg(Cryaa-TAg,Ins2-CALM1)26Ove Tg(Myh6-SOD2,Tyr)3Pne
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sox2/Sox2 Tg(Cryaa-cre)10Mlr/?
Background: involves: C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6/Pax6 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gclc/Gclc<+> Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S4/SvJaeSor * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gclc/Gclc Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S4/SvJaeSor * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr2/Fgfr2 Fgfr3/Fgfr3 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/Fgfr1 Fgfr2/Fgfr2 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Cryaa-cre,Tyr)39Mlr/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fosb/Fosb Tg(Cryaa-cre)10Mlr/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Cryaa-cre,Tyr)39Mlr/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
10915771 | J:63743
First Author: Ai Y
Year: 2000
Journal: Hum Mol Genet
Title: A mouse model of galactose-induced cataracts.
Volume: 9
Issue: 12
Pages: 1821-7
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Publication
16010031 | J:152215
 
First Author: Shen X
Year: 2005
Journal: Methods Mol Med
Title: Cardiomyocyte defects in diabetic models and protection with cardiac-targeted transgenes.
Volume: 112
Pages: 379-88
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Publication
24296248 | J:211875
 
First Author: Sun W
Year: 2014
Journal: Free Radic Biol Med
Title: Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2.
Volume: 68
Pages: 22-34
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Publication
30770771 | J:299469
First Author: Lam PT
Year: 2019
Journal: Hum Genomics
Title: Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens.
Volume: 13
Issue: 1
Pages: 10
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Publication
34554928 | J:336470
 
First Author: Shihan MH
Year: 2021
Journal: JCI Insight
Title: αVβ8 integrin targeting to prevent posterior capsular opacification.
Volume: 6
Issue: 21
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Publication
18782574 | J:146379
First Author: Garcia CM
Year: 2009
Journal: Exp Eye Res
Title: The function of VEGF-A in lens development: formation of the hyaloid capillary network and protection against transient nuclear cataracts.
Volume: 88
Issue: 2
Pages: 270-6
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Publication
18455718 | J:136711
First Author: Zhao H
Year: 2008
Journal: Dev Biol
Title: Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation.
Volume: 318
Issue: 2
Pages: 276-88
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Publication
32858001 | J:297163
First Author: Padula SL
Year: 2020
Journal: Dev Biol
Title: Lens fiber cell differentiation occurs independently of fibroblast growth factor receptor signaling in the absence of Pten.
Volume: 467
Issue: 1-2
Pages: 1-13
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Publication
36880430 | J:341334
First Author: Zhou Y
Year: 2023
Journal: FASEB J
Title: Charged multivesicular body protein 4b forms complexes with gap junction proteins during lens fiber cell differentiation.
Volume: 37
Issue: 4
Pages: e22801
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Publication
19623611 | J:151538
First Author: Rivera C
Year: 2009
Journal: Dev Dyn
Title: Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis.
Volume: 238
Issue: 9
Pages: 2292-308
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Publication
27824296 | J:264903
First Author: Hoang TV
Year: 2017
Journal: Epigenetics
Title: Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.
Volume: 12
Issue: 1
Pages: 27-40
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Publication
25268479 | J:223109
First Author: Choi JJ
Year: 2014
Journal: PLoS One
Title: A role for smoothened during murine lens and cornea development.
Volume: 9
Issue: 9
Pages: e108037
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Publication
26906157 | J:257590
First Author: Lee S
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.
Volume: 57
Issue: 2
Pages: 707-18
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Publication
24753151 | J:214344
First Author: Kerr CL
Year: 2014
Journal: Dev Dyn
Title: AP-2α is required after lens vesicle formation to maintain lens integrity.
Volume: 243
Issue: 10
Pages: 1298-309
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Publication
36359852 | J:331436
 
First Author: Novo SG
Year: 2022
Journal: Cells
Title: The Immediate Early Response of Lens Epithelial Cells to Lens Injury.
Volume: 11
Issue: 21
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Publication
21945075 | J:178484
First Author: Maddala R
Year: 2011
Journal: Dev Biol
Title: Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
Volume: 360
Issue: 1
Pages: 30-43
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Publication
28552735 | J:246153
First Author: Logan CM
Year: 2017
Journal: Dev Biol
Title: N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.
Volume: 428
Issue: 1
Pages: 118-134
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Publication
29176738 | J:257373
First Author: Logan CM
Year: 2017
Journal: Sci Rep
Title: Induction of Immune Surveillance of the Dysmorphogenic Lens.
Volume: 7
Issue: 1
Pages: 16235
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Publication
25139855 | J:214812
First Author: Chaffee BR
Year: 2014
Journal: Development
Title: Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly.
Volume: 141
Issue: 17
Pages: 3388-98
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Publication
26375880 | J:226401
First Author: Shin EH
Year: 2015
Journal: Dev Biol
Title: Sprouty gain of function disrupts lens cellular processes and growth by restricting RTK signaling.
Volume: 406
Issue: 2
Pages: 129-46
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Publication
24824078 | J:216250
First Author: Lee S
Year: 2014
Journal: PLoS One
Title: Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling.
Volume: 9
Issue: 5
Pages: e97470
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Publication
38240393 | J:350919
 
First Author: Sugiyama Y
Year: 2024
Journal: Development
Title: Fibroblast growth factor-induced lens fiber cell elongation is driven by the stepwise activity of Rho and Rac.
Volume: 151
Issue: 3
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Genotype
Genotype
Symbol: Sord/Sord Tg(Cryaa-AKR1B1)222Smch/Tg(Cryaa-AKR1B1)222Smch
Background: involves: C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sord/Sord Tg(Cryaa-AKR1B1)648Smch/Tg(Cryaa-AKR1B1)648Smch
Background: involves: C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sord/Sord Tg(Cryaa-AKR1B1)648Smch/?
Background: involves: C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sord/Sord<+> Tg(Cryaa-AKR1B1)648Smch/?
Background: involves: C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Sord/Sord<+> Tg(Cryaa-AKR1B1)222Smch/?
Background: involves: C57BL * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6/Pax6 Sox2/Sox2 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/Fgfr1 Fgfr2/Fgfr2 Fgfr3/Fgfr3 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/Fgfr1 Fgfr3/Fgfr3 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cryaa-cre,Tyr)39Mlr/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: E2f1/E2f1 E2f2/E2f2 E2f3/E2f3 Tg(Cryaa-cre)10Mlr/?
Background: involves: 129P2/OlaHsd * 129S/Sv * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
19007775 | J:146377
First Author: Graw J
Year: 2009
Journal: Exp Eye Res
Title: Genetics of crystallins: cataract and beyond.
Volume: 88
Issue: 2
Pages: 173-89
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Publication
19515997 | J:154534
First Author: Martinez G
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
Volume: 50
Issue: 10
Pages: 4794-806
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Publication
30642872 | J:270111
 
First Author: Jones W
Year: 2019
Journal: Dis Model Mech
Title: Targeted deletion of fibrillin-1 in the mouse eye results in ectopia lentis and other ocular phenotypes associated with Marfan syndrome.
Volume: 12
Issue: 1
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Publication
31404815 | J:282278
 
First Author: Zhou Y
Year: 2019
Journal: Differentiation
Title: A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation.
Volume: 109
Pages: 16-27
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Publication
23226398 | J:194778
First Author: Fan X
Year: 2012
Journal: PLoS One
Title: The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesis.
Volume: 7
Issue: 11
Pages: e50832
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Publication
7708723 | J:106642
First Author: Lee AY
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.
Volume: 92
Issue: 7
Pages: 2780-4
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Publication
26218911 | J:230953
First Author: De Maria A
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Birc7: A Late Fiber Gene of the Crystalline Lens.
Volume: 56
Issue: 8
Pages: 4823-34
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Publication
23479732 | J:198392
First Author: Morishita H
Year: 2013
Journal: J Biol Chem
Title: Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation.
Volume: 288
Issue: 16
Pages: 11436-47
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Genotype
Genotype
Symbol: Atg5/Atg5 Tg(CAG-EGFP/Map1lc3b)53Nmz/? Tg(Cryaa-cre)10Mlr/?
Background: involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Publication
38334649 | J:346802
 
First Author: Zhou Y
Year: 2024
Journal: Cells
Title: A Cataract-Causing Mutation in the TRPM3 Cation Channel Disrupts Calcium Dynamics in the Lens.
Volume: 13
Issue: 3
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Publication
30059908 | J:264269
 
First Author: Azimi M
Year: 2018
Journal: Differentiation
Title: Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens.
Volume: 102
Pages: 40-52
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Publication
17470285 | J:134428
 
First Author: Pirity MK
Year: 2007
Journal: BMC Dev Biol
Title: Rybp, a polycomb complex-associated protein, is required for mouse eye development.
Volume: 7
Pages: 39
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Publication
15161860 | J:90292
First Author: Zhao H
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice.
Volume: 45
Issue: 6
Pages: 1930-9
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Publication
28716713 | J:249114
First Author: Cavalheiro GR
Year: 2017
Journal: Dev Biol
Title: N-myc regulates growth and fiber cell differentiation in lens development.
Volume: 429
Issue: 1
Pages: 105-117
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Publication
28237965 | J:242077
First Author: Mao M
Year: 2017
Journal: Dis Model Mech
Title: Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse.
Volume: 10
Issue: 4
Pages: 475-485
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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