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Search results 701 to 800 out of 935 for Dbh

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7855298
Assay Type: RT-PCR
Annotation Date: 2025-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737319
Stage: TS19
Assay Id: MGI:7855511
Age: embryonic day 11.5
Image: S2
Specimen Label: +/-
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7855298
Assay Type: RT-PCR
Annotation Date: 2025-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:7855511
Age: embryonic day 12.5
Image: S2
Specimen Label: -/-
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3526028
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Specimen Label: 1
Detected: false
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760623
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Specimen Label: Table 1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Note: Expression is seen in the uteric bud tips, as well as other non-uteric bud populations.
Specimen Label: 2 - Category 2
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802103
Note: kidney
Specimen Label: JAX_1802103
Detected: true
Specimen Num: 19
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802102
Specimen Label: JAX_1802102
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802104
Specimen Label: JAX_1802104
Detected: true
Specimen Num: 20
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752923
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Specimen Label: Table 1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802096
Specimen Label: JAX_1802096
Detected: true
Specimen Num: 12
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802094
Specimen Label: JAX_1802094
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802093
Specimen Label: JAX_1802093
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2509123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Image: 7B
Note: Expression is seen in the chondrocytes in the entire anterior-posterior axis.
Specimen Label: 7B
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760723
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Specimen Label: Table 1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1680119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5920007
Age: embryonic day 11.5
Image: 1E
Specimen Label: 1E
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802100
Specimen Label: JAX_1802100
Detected: true
Specimen Num: 16
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Specimen Label: Table 1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1760823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1653614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:5291673
Age: embryonic day 9.0
Image: E9.0
Note: Expression is present in the otic vesicle.
Specimen Label: E9.0
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802095
Specimen Label: JAX_1802095
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: Expression is in the subplate.
Specimen Label: 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: In this mutant all expressing subplate cells are shifted to the superplate.
Specimen Label: 2C
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: All expressing subplate cells are relocated to the middle of the cortical plate in this mutant.
Specimen Label: 2G
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: Expression is in the subplate.
Specimen Label: 2K
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5750709
Age: embryonic day 18.0
Specimen Label: 4 E18
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5750709
Age: postnatal day 3
Note: Expression is in some cells in the subplate.
Specimen Label: 4 P3
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: Expression is in some cells in the subplate.
Specimen Label: 4 P8
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 21
Note: Expression is in some cells in the subplate.
Specimen Label: 4 P21
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal adult
Note: Expression is in a few cells in the subplate.
Specimen Label: 4 Adult
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Specimen Label: 6 - Category C - E15.5
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672820
Stage: TS20
Assay Id: MGI:6506758
Age: embryonic day 12.5
Specimen Label: 6 - Category C - E12.5
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802110
Specimen Label: JAX_1802110
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_1329899
Specimen Label: JAX_1329899
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_1329900
Specimen Label: JAX_1329900
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_1329901
Specimen Label: JAX_1329901
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_1329902
Specimen Label: JAX_1329902
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_619791
Specimen Label: JAX_619791
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_619793
Specimen Label: JAX_619793
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_619795
Specimen Label: JAX_619795
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6692087
Age: embryonic day 12.5
Image: JAX_619797
Specimen Label: JAX_619797
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802097
Specimen Label: JAX_1802097
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802106
Specimen Label: JAX_1802106
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: The authors state that in some mice expression was seen in cortical layer V (shown).
Specimen Label: 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525927
Stage: TS27
Assay Id: MGI:5750709
Age: postnatal day 3
Specimen Label: 4 P3
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Specimen Label: 4 P8
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 21
Specimen Label: 4 P21
Detected: false
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal adult
Specimen Label: 4 Adult
Detected: false
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5750622
Assay Type: RNA in situ
Annotation Date: 2016-03-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5750709
Age: postnatal day 8
Note: The authors state that in some mice expression was seen in cortical layer V. Shown is a specimen where expression is absent.
Specimen Label: 2C
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802112
Specimen Label: JAX_1802112
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6178252
Assay Type: RNA in situ
Annotation Date: 2023-11-28
Strength: Present
Sex: Male
Emaps: EMAPS:3583128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7561607
Age: postnatal day 56
Image: S3
Specimen Label: S3
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802113
Specimen Label: JAX_1802113
Detected: true
Specimen Num: 29
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3589023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3589023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Image: 7B
Note: Expression is seen in the chondrocytes in the entire anterior-posterior axis. Areas of expression include the perichondrium of the lateral turbinates.
Specimen Label: 7B
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Note: Expression is restricted to the distal tip.
Specimen Label: 3 - Class I
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Specimen Label: 6 - Category C - E15.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6506758
Age: embryonic day 12.5
Specimen Label: 5 - E12.5
Detected: true
Specimen Num: 3
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Specimen Label: 5 - E15.5
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6506543
Assay Type: RNA in situ
Annotation Date: 2021-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6506758
Age: embryonic day 15.5
Specimen Label: 2 - Category 2
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760423
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Note: Expression is not seen in the vestibule.
Specimen Label: Table 1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802099
Specimen Label: JAX_1802099
Detected: true
Specimen Num: 15
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1606214
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:5291673
Age: embryonic day 9.0
Image: E9.0
Specimen Label: E9.0
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802107
Specimen Label: JAX_1802107
Detected: true
Specimen Num: 23
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619112
Pattern: Not Specified
Stage: TS12
Assay Id: MGI:5291673
Age: embryonic day 8.0
Image: E8.0
Specimen Label: E8.0
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619113
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5291673
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619114
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:5291673
Age: embryonic day 9.0
Image: E9.0
Specimen Label: E9.0
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619112
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5291673
Age: embryonic day 8.0
Image: 3F left
Note: Expression is present in the posterior notochord.
Specimen Label: 3F left
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:1514927
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619114
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:5291673
Age: embryonic day 9.0
Image: 3F right
Note: Expression is present in the posterior notochord.
Specimen Label: 3F right
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802109
Specimen Label: JAX_1802109
Detected: true
Specimen Num: 25
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802111
Specimen Label: JAX_1802111
Detected: true
Specimen Num: 27
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1680519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5920007
Age: embryonic day 11.5
Image: 1E
Note: Expression is seen in the lateral region.
Specimen Label: 1E
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802098
Specimen Label: JAX_1802098
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802105
Specimen Label: JAX_1802105
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802101
Specimen Label: JAX_1802101
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692087
Age: postnatal adult
Image: JAX_1802108
Specimen Label: JAX_1802108
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5913902
Assay Type: RNA in situ
Annotation Date: 2017-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3789423
Stage: TS23
Assay Id: MGI:5920007
Age: embryonic day 15.5
Specimen Label: Table 1
Detected: false
Specimen Num: 4
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•
Publication
- | J:65617
   
First Author: Osada N
Year: 2000
Journal: GenBank Submission
Title: Mus musculus brain cDNA, clone MNCb-5203
Pages: AB041606
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Protein
Q9CXI3
Organism: Mus musculus/domesticus
Length: 613  
Fragment?: false
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•
Protein
Q7TT41
Organism: Mus musculus/domesticus
Length: 619  
Fragment?: false
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•
Publication
1988445 | -
First Author: Stoffers DA
Year: 1991
Journal: J Biol Chem
Title: Characterization of novel mRNAs encoding enzymes involved in peptide alpha-amidation.
Volume: 266
Issue: 3
Pages: 1701-7
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•
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•
Publication
1448112 | J:3062
First Author: Ouafik LH
Year: 1992
Journal: Mol Endocrinol
Title: The multifunctional peptidylglycine alpha-amidating monooxygenase gene: exon/intron organization of catalytic, processing, and routing domains.
Volume: 6
Issue: 10
Pages: 1571-84
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•
•
•
•
Publication
11028916 | J:66694
First Author: Prigge ST
Year: 2000
Journal: Cell Mol Life Sci
Title: New insights into copper monooxygenases and peptide amidation: structure, mechanism and function.
Volume: 57
Issue: 8-9
Pages: 1236-59
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•
•
•
Publication
16301310 | -
First Author: Klinman JP
Year: 2006
Journal: J Biol Chem
Title: The copper-enzyme family of dopamine beta-monooxygenase and peptidylglycine alpha-hydroxylating monooxygenase: resolving the chemical pathway for substrate hydroxylation.
Volume: 281
Issue: 6
Pages: 3013-6
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•
•
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Publication
10993678 | -
First Author: Jiang N
Year: 2000
Journal: Dev Biol
Title: PHM is required for normal developmental transitions and for biosynthesis of secretory peptides in Drosophila.
Volume: 226
Issue: 1
Pages: 118-36
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•
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Publication
15198673 | -
First Author: Han M
Year: 2004
Journal: J Neurochem
Title: Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2.
Volume: 90
Issue: 1
Pages: 129-41
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Protein Domain
IPR000720 | PHM/PAL
Type: Family
Description: In vertebrates, peptidylglycine alpha-amidating monooxygenase (PAM) is a multifunctional protein found in secretory granules. The protein contains two enzymes, peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL), that act sequentially to catalyse the alpha-amidation of neuroendocrine peptides [, ]: peptidylglycine + ascorbate + O2= peptidyl-(2-hydroxyglycine) + dehydroascorbate + H2OThe product is unstable and dismutates to glyoxylate and the corresponding desglycine peptide amide. The first step of the reaction is catalysed by peptidylglycine alpha-hydroxylating monooxygenase (PHM), and is dependent on copper, ascorbate and molecular oxygen; peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) catalyses the second step of the reaction []. PHM share protein sequence similarity with dopamine-beta-monooxygenases (DBH), a class of ascorbate-dependent enzymes that requires copper as a cofactor and uses ascorbate as an electron donor. PHM and DBH share a few regions of sequence similarity, some of which contain clusters of conserved histidine residues that may be involved in copper binding [, ].Interestingly, in Drosophila, the PHM and PAL enzyme are not fused. The Drosophila genome predicts expression of one monofunctional PHM gene and two monofunctional PAL genes []. Drosophila PHM encodes an active enzyme that is required for peptide amidation in vivo [], while both PAL proteins display PAL enzymatic activity and are involved in neuroendocrine biosynthesis [].
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Publication
10395798 | J:56277
First Author: Yokoyama M
Year: 1999
Journal: Genomics
Title: Genomic structure and functional characterization of NBPhox (PMX2B), a homeodomain protein specific to catecholaminergic cells that is involved in second messenger-mediated transcriptional activation.
Volume: 59
Issue: 1
Pages: 40-50
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Publication
22172526 | J:180299
First Author: Sourris KC
Year: 2012
Journal: Free Radic Biol Med
Title: Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes.
Volume: 52
Issue: 3
Pages: 716-723
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Publication
15372500 | J:100208
First Author: Matsushita N
Year: 2004
Journal: J Neurosci Res
Title: Fate of transient catecholaminergic cell types revealed by site-specific recombination in transgenic mice.
Volume: 78
Issue: 1
Pages: 7-15
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•
Publication
16584562 | J:111122
 
First Author: Zhao Z
Year: 2006
Journal: BMC Neurosci
Title: A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.
Volume: 7
Pages: 29
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•
•
•
Publication
29424419 | J:262533
First Author: Johnson CS
Year: 2018
Journal: J Comp Neurol
Title: Neurotransmitter diversity in pre-synaptic terminals located in the parvicellular neuroendocrine paraventricular nucleus of the rat and mouse hypothalamus.
Volume: 526
Issue: 8
Pages: 1287-1306
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Publication
39038954 | J:355707
 
First Author: McCosh RB
Year: 2024
Journal: J Neurosci
Title: Norepinephrine Neurons in the Nucleus of the Solitary Tract Suppress Luteinizing Hormone Secretion in Female Mice.
Volume: 44
Issue: 34
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•
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Publication
11034547 | J:45820
First Author: Adachi M
Year: 2000
Journal: DNA Cell Biol
Title: Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription.
Volume: 19
Issue: 9
Pages: 539-54
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Publication
9705334 | J:49248
First Author: Ishiguro H
Year: 1998
Journal: J Biol Chem
Title: Identification and characterization of a novel phorbol ester-responsive DNA sequence in the 5'-flanking region of the human dopamine beta-hydroxylase gene.
Volume: 273
Issue: 34
Pages: 21941-9
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•
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Publication
9724817 | J:49798
First Author: Mayerhofer A
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Oocytes are a source of catecholamines in the primate ovary: evidence for a cell-cell regulatory loop.
Volume: 95
Issue: 18
Pages: 10990-5
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Publication
19254708 | J:148365
First Author: Schmidt M
Year: 2009
Journal: Dev Biol
Title: The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons.
Volume: 329
Issue: 2
Pages: 191-200
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Publication
24252179 | J:319040
 
First Author: Kim S
Year: 2014
Journal: Exp Neurol
Title: Alpha-synuclein interferes with cAMP/PKA-dependent upregulation of dopamine β-hydroxylase and is associated with abnormal adaptive responses to immobilization stress.
Volume: 252
Pages: 63-74
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Publication
1542654 | J:328031
First Author: Kobayashi K
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Genetic alteration of catecholamine specificity in transgenic mice.
Volume: 89
Issue: 5
Pages: 1631-5
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Publication
28288124 | J:244606
First Author: Abe C
Year: 2017
Journal: Nat Neurosci
Title: C1 neurons mediate a stress-induced anti-inflammatory reflex in mice.
Volume: 20
Issue: 5
Pages: 700-707
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Publication
26758839 | J:228866
First Author: Olivas A
Year: 2016
Journal: J Neurosci
Title: Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130.
Volume: 36
Issue: 2
Pages: 479-88
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Publication
19036879 | J:151820
First Author: Parlato R
Year: 2009
Journal: Endocrinology
Title: Conditional inactivation of glucocorticoid receptor gene in dopamine-beta-hydroxylase cells impairs chromaffin cell survival.
Volume: 150
Issue: 4
Pages: 1775-81
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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