|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 701 to 800 out of 826 for Dcn

<< First    < Previous  |  Next >    Last >>
0.018s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Protein
O88809
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
•
•
•
•
•
Allele
Dcn<em1Smoc> | MGI:7289286
Name: decorin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Publication
35294867 | J:349597
 
First Author: Hulshof LA
Year: 2022
Journal: Neurobiol Aging
Title: Both male and female APPswe/PSEN1dE9 mice are impaired in spatial memory and cognitive flexibility at 9 months of age.
Volume: 113
Pages: 28-38
•
•
•
•
•
Strain
MGI:7718027 | C57BL/6JSmoc-Dcn<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Allele
Tg(Dcn-EGFP)PA28Gsat | MGI:5523328
Name: transgene insertion PA28, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
•
•
•
•
•
HT Experiment
GSE214244 | Single nucleus RNA-seq of brain regions showing high-low Abeta plaque pathology in a mouse model of Alzheimer's disease
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Allele
Tg(CAG-cat,-Dcn*)#Debi | MGI:5298093
Name: transgene insertion, David E Birk
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
•
•
•
•
•
Strain
MGI:5523288 | STOCK Tg(Dcn-EGFP)PA28Gsat/Mmucd
Attribute String: transgenic, mutant stock
•
•
•
•
•
Protein
Q8K0V2
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
•
•
•
•
•
Protein
Q8CCA0
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
•
•
•
•
•
Protein
Q9CXV9
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
•
•
•
•
•
Protein
Q3UT23
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
•
•
•
•
•
Protein
A0A1L1SSU2
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
•
•
•
•
•
Protein
A0A0G2JGV7
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
•
•
•
•
•
Protein
A0A140T8R8
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
•
•
•
•
•
Protein
A0A1N9M8A6
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
•
•
•
•
•
Protein
Q8C5X2
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: false
•
•
•
•
•
Publication
15988528 | -
First Author: Kurz T
Year: 2005
Journal: Nature
Title: The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.
Volume: 435
Issue: 7046
Pages: 1257-61
•
•
•
•
•
Publication
18206966 | -
First Author: Kurz T
Year: 2008
Journal: Mol Cell
Title: Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.
Volume: 29
Issue: 1
Pages: 23-35
•
•
•
•
•
Publication
23201271 | -
First Author: Monda JK
Year: 2013
Journal: Structure
Title: Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.
Volume: 21
Issue: 1
Pages: 42-53
•
•
•
•
•
Publication
26906416 | -
First Author: Keuss MJ
Year: 2016
Journal: J Cell Sci
Title: Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.
Volume: 129
Issue: 7
Pages: 1441-54
•
•
•
•
•
Protein
D3Z664
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
•
•
•
•
•
Protein
D6RHK6
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
•
•
•
•
•
Protein
F7A063
Organism: Mus musculus/domesticus
Length: 31  
Fragment?: true
•
•
•
•
•
Protein
D3Z0Q3
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
•
•
•
•
•
Protein
D6RJL1
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
•
•
•
•
•
Publication
17905859 | -
First Author: Biswas KK
Year: 2007
Journal: Plant Physiol
Title: Genetic characterization of mutants resistant to the antiauxin p-chlorophenoxyisobutyric acid reveals that AAR3, a gene encoding a DCN1-like protein, regulates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid in Arabidopsis roots.
Volume: 145
Issue: 3
Pages: 773-85
•
•
•
•
•
Protein Domain
IPR014764 | DCN-prot
Type: Family
Description: The eukaryotic defective in cullin neddylation (DCN) protein family, contributes to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. These multi-protein complexes are required for polyubiquitination and subsequent degradation of target proteins by the 26S proteasome[, , ]. Proteins in the DCN family include:Yeast DCN1.Vertebrate DCN1-like protein 1-5.Plant Defective in cullin neddylation protein AAR3 [].DCN family proteins all contain a Potentiating neddylation (PONY) domain (), contains a cullin-binding surface within its C-terminal region and is sufficient to promote neddylation [, ]. The N-terminal region of the protein often contains a UBA-like domain.
•
•
•
•
•
Protein Domain
IPR005176 | PONY_dom
Type: Domain
Description: This domain is found in the eukaryotic family defective in cullin neddylation, which includes DCN1 and DCN1-like proteins. Proteins of the DCN family may contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes, which are multi-protein complexes required for polyubiquitination and subsequent degradation of target proteins by the 26S proteasome [, ].The structure of this domain is composed entirely of alpha helices [, ]. It has been referred to as potentiating neddylation domain (PONY) and can be found in association with an N-terminal UBA domain. The PONY domain contains a cullin-binding surface within its C-terminal region and is sufficient to promote neddylation [, ].
•
•
•
•
•
Protein Domain
IPR042460 | DCN1-like_PONY
Type: Homologous_superfamily
Description: This superfamily represents a domain is found in DCN1-like proteins. Proteins of the DCN family may contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes, which are multi-protein complexes required for polyubiquitination and subsequent degradation of target proteins by the 26S proteasome [, ].The structure of this domain is composed entirely of alpha helices [, ]. It has been referred to as potentiating neddylation domain (PONY) and can be found in association with an N-terminal UBA domain. The PONY domain contains a cullin-binding surface within its C-terminal region and is sufficient to promote neddylation [, ].
•
•
•
•
•
Protein
D3Z4A7
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
•
•
•
•
•
Protein
A0A1B0GXL7
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
•
•
•
•
•
Protein
D3Z7G2
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
•
•
•
•
•
Protein
D3YWG7
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: true
•
•
•
•
•
Protein
A0A0G2JDN9
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
•
•
•
•
•
Protein
B7ZMU0
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
•
•
•
•
•
Publication
17597076 | -
First Author: Yang X
Year: 2007
Journal: J Biol Chem
Title: Structural basis for the function of DCN-1 in protein Neddylation.
Volume: 282
Issue: 34
Pages: 24490-4
•
•
•
•
•
Publication
18826954 | J:143467
First Author: Kim AY
Year: 2008
Journal: J Biol Chem
Title: SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
Volume: 283
Issue: 48
Pages: 33211-20
•
•
•
•
•
Publication
1353400 | J:40
First Author: Kakehata S
Year: 1992
Journal: Brain Res
Title: Glycine response in isolated dorsal cochlear nucleus of C57BL/6J mouse.
Volume: 574
Issue: 1-2
Pages: 21-5
•
•
•
•
•
Protein
Q9QZ73
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
Q8BZJ7
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
Q99NE7
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
Q3TMV8
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
G5E8Q6
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
•
•
•
•
•
Protein
A0A1Y7VP24
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
•
•
•
•
•
Protein
A0A0N4SW97
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
•
•
•
•
•
Protein
Q3TSY8
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(CAG-cat,-Dcn*)#Debi/? Tg(Kera-cre)KC4.3Wwk/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
26647187 | J:228304
First Author: Kalappa BI
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: AMPA receptor inhibition by synaptically released zinc.
Volume: 112
Issue: 51
Pages: 15749-54
•
•
•
•
•
Publication
29490269 | J:270754
First Author: Low AYT
Year: 2018
Journal: Cell Rep
Title: Precision of Discrete and Rhythmic Forelimb Movements Requires a Distinct Neuronal Subpopulation in the Interposed Anterior Nucleus.
Volume: 22
Issue: 9
Pages: 2322-2333
•
•
•
•
•
Publication
33317052 | J:324337
 
First Author: Daquinag AC
Year: 2020
Journal: Cells
Title: Glycosaminoglycan Modification of Decorin Depends on MMP14 Activity and Regulates Collagen Assembly.
Volume: 9
Issue: 12
•
•
•
•
•
Publication
32347796 | J:291939
   
First Author: Khan MM
Year: 2020
Journal: Elife
Title: Loss of Doc2b does not influence transmission at Purkinje cell to deep nuclei synapses under physiological conditions.
Volume: 9
•
•
•
•
•
Publication
33259288 | J:301450
   
First Author: Turecek J
Year: 2020
Journal: Elife
Title: Cerebellar and vestibular nuclear synapses in the inferior olive have distinct release kinetics and neurotransmitters.
Volume: 9
•
•
•
•
•
Publication
34551285 | J:317825
First Author: Lu B
Year: 2021
Journal: Cell Rep
Title: Cerebellar spreading depolarization mediates paroxysmal movement disorder.
Volume: 36
Issue: 12
Pages: 109743
•
•
•
•
•
Protein
G5E8Q5
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: false
•
•
•
•
•
Protein
A0A0G2JDM0
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
•
•
•
•
•
Protein
A0A0N4SW71
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: false
•
•
•
•
•
Protein
A0A0G2JEA2
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
•
•
•
•
•
Publication
20696900 | J:221027
First Author: Poulogiannis G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
Volume: 107
Issue: 34
Pages: 15145-50
•
•
•
•
•
Publication
16540585 | J:106708
First Author: Fink AJ
Year: 2006
Journal: J Neurosci
Title: Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip.
Volume: 26
Issue: 11
Pages: 3066-76
•
•
•
•
•
Publication
16139369 | J:103543
First Author: Takaoka Y
Year: 2005
Journal: Brain Res Dev Brain Res
Title: Expression of reelin in the dorsal cochlear nucleus of the mouse.
Volume: 159
Issue: 2
Pages: 127-34
•
•
•
•
•
Publication
7260600 | J:6554
First Author: Roffler-Tarlov S
Year: 1981
Journal: Brain Res
Title: Quantitative examination of the deep cerebellar nuclei in the staggerer mutant mouse.
Volume: 215
Issue: 1-2
Pages: 49-59
•
•
•
•
•
Publication
24727095 | J:212116
 
First Author: Luna-Cancalon K
Year: 2014
Journal: Neurobiol Dis
Title: Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice.
Volume: 67
Pages: 140-8
•
•
•
•
•
Publication
12355415 | J:126831
First Author: Sultan F
Year: 2002
Journal: J Comp Neurol
Title: Quantitative organization of neurotransmitters in the deep cerebellar nuclei of the Lurcher mutant.
Volume: 452
Issue: 4
Pages: 311-23
•
•
•
•
•
Publication
23999154 | J:215430
 
First Author: Carulli D
Year: 2013
Journal: Mol Cell Neurosci
Title: Modulation of semaphorin3A in perineuronal nets during structural plasticity in the adult cerebellum.
Volume: 57
Pages: 10-22
•
•
•
•
•
Publication
25796568 | J:259595
 
First Author: Perez-Rosello T
Year: 2015
Journal: Neurobiol Dis
Title: Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission.
Volume: 81
Pages: 14-9
•
•
•
•
•
Publication
19439493 | J:149533
First Author: Fujiyama T
Year: 2009
Journal: Development
Title: Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.
Volume: 136
Issue: 12
Pages: 2049-58
•
•
•
•
•
Publication
20876357 | J:165661
First Author: Kim TS
Year: 2010
Journal: Dis Model Mech
Title: The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress.
Volume: 3
Issue: 11-12
Pages: 752-62
•
•
•
•
•
Publication
27151208 | J:234119
First Author: Cai X
Year: 2016
Journal: Dev Biol
Title: Bhlhb5::flpo allele uncovers a requirement for Bhlhb5 for the development of the dorsal cochlear nucleus.
Volume: 414
Issue: 2
Pages: 149-60
•
•
•
•
•
Publication
20566869 | J:162070
First Author: Chen X
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels.
Volume: 107
Issue: 27
Pages: 12323-8
•
•
•
•
•
Publication
29523816 | J:262687
First Author: Cheron G
Year: 2018
Journal: Sci Rep
Title: Purkinje cell BKchannel ablation induces abnormal rhythm in deep cerebellar nuclei and prevents LTD.
Volume: 8
Issue: 1
Pages: 4220
•
•
•
•
•
Publication
17948875 | J:132036
First Author: Miko IJ
Year: 2007
Journal: J Comp Neurol
Title: Auditory brainstem neural activation patterns are altered in EphA4- and ephrin-B2-deficient mice.
Volume: 505
Issue: 6
Pages: 669-81
•
•
•
•
•
Publication
18634763 | J:139805
 
First Author: Thompson AM
Year: 2008
Journal: Brain Res
Title: Serotonin immunoreactivity in auditory brainstem neurons of the postnatal monoamine oxidase-A knockout mouse.
Volume: 1228
Pages: 58-67
•
•
•
•
•
Publication
34381449 | J:320636
 
First Author: Kiripolsky J
Year: 2021
Journal: Front Immunol
Title: Immune-Intrinsic Myd88 Directs the Production of Antibodies With Specificity for Extracellular Matrix Components in Primary Sjögren's Syndrome.
Volume: 12
Pages: 692216
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom