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Search results 701 to 800 out of 805 for Ddit3

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Type Details Score
Publication
35377412 | J:333870
First Author: Jazwiec PA
Year: 2022
Journal: Biol Reprod
Title: Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism†.
Volume: 107
Issue: 2
Pages: 574-589
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Publication
18776938 | J:141141
First Author: Song B
Year: 2008
Journal: J Clin Invest
Title: Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
Volume: 118
Issue: 10
Pages: 3378-89
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Publication
29180572 | J:253982
 
First Author: Norlin S
Year: 2018
Journal: Development
Title: The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.
Volume: 145
Issue: 1
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Publication
37353485 | J:337474
First Author: Cobo I
Year: 2023
Journal: Nat Commun
Title: NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.
Volume: 14
Issue: 1
Pages: 3761
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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Publication
26173459 | J:226104
First Author: Wang F
Year: 2015
Journal: Am J Physiol Endocrinol Metab
Title: ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development.
Volume: 309
Issue: 5
Pages: E487-99
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Publication
39181129 | J:353791
     
First Author: Xu L
Year: 2024
Journal: Cell Stem Cell
Title: Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells.
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Publication
26816051 | J:250104
First Author: Flodby P
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development.
Volume: 55
Issue: 1
Pages: 135-49
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Publication
22643896 | J:243333
 
First Author: Tian E
Year: 2012
Journal: Nat Commun
Title: O-glycosylation modulates integrin and FGF signalling by influencing the secretion of basement membrane components.
Volume: 3
Pages: 869
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Publication
39328932 | J:354587
First Author: Nedomova M
Year: 2024
Journal: iScience
Title: DDI2 protease controls embryonic development and inflammation via TCF11/NRF1.
Volume: 27
Issue: 10
Pages: 110893
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Publication
15010206 | J:88423
First Author: GarcĂ­a-Frigola C
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
Volume: 122
Issue: 2
Pages: 133-50
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Publication
37829188 | J:356223
First Author: Martinez-Ramirez AS
Year: 2022
Journal: Gastro Hep Adv
Title: Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development.
Volume: 1
Issue: 5
Pages: 807-823
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Publication
39747033 | J:360776
First Author: Di Michele M
Year: 2025
Journal: Nat Commun
Title: E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Volume: 16
Issue: 1
Pages: 67
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Publication
36841836 | J:333724
First Author: Park EJ
Year: 2023
Journal: Nat Commun
Title: Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation.
Volume: 14
Issue: 1
Pages: 1097
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Publication
24859004 | J:219394
First Author: Boroviak T
Year: 2014
Journal: Nat Cell Biol
Title: The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.
Volume: 16
Issue: 6
Pages: 516-28
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Publication
22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: DDIT3 upstream open reading frame protein
Type: chain
End: 34
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Allele
Ddit3<em2Smoc> | MGI:7289297
Name: DNA-damage inducible transcript 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
21285359 | -
First Author: Palam LR
Year: 2011
Journal: J Biol Chem
Title: Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation.
Volume: 286
Issue: 13
Pages: 10939-49
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Strain
MGI:6770692 | C57BL/6JSmoc-Ddit3<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Ddit3<em1Smoc> | MGI:7289296
Name: DNA-damage inducible transcript 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Tg(Prrx1-FUS/DDIT3)1Mete | MGI:5428676
Name: transgene insertion 1, Melissa Terry
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Fus<tm1(DDIT3)Dron> | MGI:2177655
Name: fused in sarcoma; targeted mutation 1, David Ron
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:5430314 | B6;CBA-Tg(Prrx1-FUS/DDIT3)1Mete/J
Attribute String: mutant stock, transgenic
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Strain
MGI:6475108 | C57BL/6JSmoc-Ddit3<tm1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Tg(Prrx1-FUS/DDIT3)1Mete/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Protein Domain
IPR033523 | IRE2
Type: Family
Description: Human IRE2 induces translational repression through 28S ribosomal RNA cleavage in response to ER stress []. However, mouse IRE2 does not have this function, instead, it plays a role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis [].
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Publication
22293175 | J:184491
First Author: Charytonowicz E
Year: 2012
Journal: J Clin Invest
Title: PPARÎł agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma.
Volume: 122
Issue: 3
Pages: 886-98
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Strain
MGI:5763765 | 129S6/SvEvTac-Fus<tm1(DDIT3)Dron>
Attribute String: targeted mutation, mutant strain, coisogenic
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Publication
10220412 | J:75732
First Author: Kuroda M
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Induction of a secreted protein by the myxoid liposarcoma oncogene.
Volume: 96
Issue: 9
Pages: 5025-30
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Publication
10654943 | J:60224
First Author: Kuroda M
Year: 2000
Journal: EMBO J
Title: Male sterility and enhanced radiation sensitivity in TLS(-/-) mice.
Volume: 19
Issue: 3
Pages: 453-62
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Genotype
Genotype
Symbol: Fus/Fus
Background: involves: 129S6/SvEvTac * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fus/Fus
Background: 129S6/SvEvTac-Fus
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trp53/Trp53 Tg(Prrx1-FUS/DDIT3)1Mete/?
Background: involves: 129S2/SvPas * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Publication
9755171 | J:57921
First Author: Wang XZ
Year: 1998
Journal: EMBO J
Title: Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
Volume: 17
Issue: 19
Pages: 5708-17
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Publication
11175748 | J:67159
First Author: Iwawaki T
Year: 2001
Journal: Nat Cell Biol
Title: Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.
Volume: 3
Issue: 2
Pages: 158-64
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Publication
28128204 | J:244198
 
First Author: Liu J
Year: 2017
Journal: Nat Commun
Title: A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability.
Volume: 8
Pages: 14186
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Publication
12637535 | -
First Author: Liu CY
Year: 2003
Journal: J Biol Chem
Title: Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha.
Volume: 278
Issue: 20
Pages: 17680-7
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Publication
11779464 | -
First Author: Yoshida H
Year: 2001
Journal: Cell
Title: XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.
Volume: 107
Issue: 7
Pages: 881-91
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Publication
21317875 | -
First Author: Ali MM
Year: 2011
Journal: EMBO J
Title: Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response.
Volume: 30
Issue: 5
Pages: 894-905
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Protein Domain
IPR045133 | IRE1/2-like
Type: Family
Description: This entry includes IRE1/2 and related proteins. Human IRE1 is a transmembrane protein kinase essential for the endoplasmic reticulum (ER) unfolded protein response (UPR) [, , , , , ]. IRE1 is activated by autophosphorylation through its cytoplasmic kinase domain, and this leads to activation of the C-terminal ribonuclease domain, which splices Xbp1 mRNA generating an active Xbp1s transcriptional activator [].Human IRE2 induces translational repression through 28S ribosomal RNA cleavage in response to ER stress []. However, mouse IRE2 does not have this function, instead, it plays a role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis [].
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Publication
23836031 | J:202248
First Author: O'Neill CM
Year: 2013
Journal: Endocrinology
Title: Circulating levels of IL-1B+IL-6 cause ER stress and dysfunction in islets from prediabetic male mice.
Volume: 154
Issue: 9
Pages: 3077-88
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Publication
31492921 | J:284061
First Author: Bensellam M
Year: 2019
Journal: Sci Rep
Title: Phlda3 regulates beta cell survival during stress.
Volume: 9
Issue: 1
Pages: 12827
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Publication
30045879 | J:300042
First Author: Hegyi E
Year: 2019
Journal: Gut
Title: Human CPA1 mutation causes digestive enzyme misfolding and chronic pancreatitis in mice.
Volume: 68
Issue: 2
Pages: 301-312
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Publication
21103982 | J:166437
First Author: Cantley J
Year: 2011
Journal: Diabetologia
Title: Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo.
Volume: 54
Issue: 2
Pages: 380-9
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Publication
32332705 | J:304020
First Author: Li S
Year: 2020
Journal: Cell Death Dis
Title: CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.
Volume: 11
Issue: 4
Pages: 279
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Publication
25926690 | J:222774
First Author: Alam SM
Year: 2015
Journal: Reproduction
Title: Identification of target genes for a prolactin family paralog in mouse decidua.
Volume: 149
Issue: 6
Pages: 625-32
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Publication
23830192 | J:258807
First Author: Cojocari D
Year: 2013
Journal: Radiother Oncol
Title: New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia.
Volume: 108
Issue: 3
Pages: 541-7
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Protein
B1ARJ5
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Protein
Q3TBZ5
Organism: Mus musculus/domesticus
Length: 408  
Fragment?: false
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Protein
B1ATQ7
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: false
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Publication
9637683 | -
First Author: Tirasophon W
Year: 1998
Journal: Genes Dev
Title: A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells.
Volume: 12
Issue: 12
Pages: 1812-24
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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