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Search results 701 to 800 out of 928 for Epcam

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Type Details Score
Publication
27531557 | J:289492
First Author: Yi J
Year: 2016
Journal: Hepatology
Title: Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.
Volume: 64
Issue: 5
Pages: 1757-1772
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Publication
21377456 | J:169829
First Author: Pyrgaki C
Year: 2011
Journal: Dev Biol
Title: Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion.
Volume: 353
Issue: 1
Pages: 38-49
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Publication
19369401 | J:148015
First Author: Zong Y
Year: 2009
Journal: Development
Title: Notch signaling controls liver development by regulating biliary differentiation.
Volume: 136
Issue: 10
Pages: 1727-39
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Publication
36458554 | J:333559
 
First Author: Rupani DN
Year: 2023
Journal: Development
Title: Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Volume: 150
Issue: 2
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Publication
24850856 | J:213579
First Author: Liao HF
Year: 2014
Journal: Development
Title: DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells.
Volume: 141
Issue: 12
Pages: 2402-13
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Publication
26265072 | J:250152
 
First Author: Hu X
Year: 2015
Journal: Sci Rep
Title: Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice.
Volume: 5
Pages: 12982
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Publication
31953387 | J:284576
First Author: Kim JE
Year: 2020
Journal: Nat Commun
Title: Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches.
Volume: 11
Issue: 1
Pages: 334
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Publication
31772170 | J:283792
First Author: Seishima R
Year: 2019
Journal: Nat Commun
Title: Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.
Volume: 10
Issue: 1
Pages: 5378
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Publication
35320729 | J:324832
First Author: Sun Y
Year: 2022
Journal: Cell Rep
Title: Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.
Volume: 38
Issue: 12
Pages: 110542
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Publication
37573008 | J:339600
 
First Author: Hermosilla Aguayo V
Year: 2023
Journal: Dev Biol
Title: ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.
Volume: 503
Pages: 25-42
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Publication
37096042 | J:336513
First Author: Patzek S
Year: 2023
Journal: iScience
Title: Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia.
Volume: 26
Issue: 4
Pages: 106500
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Publication
33230114 | J:299860
First Author: Jin L
Year: 2020
Journal: Nat Commun
Title: STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.
Volume: 11
Issue: 1
Pages: 5941
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Publication
28380258 | J:309653
First Author: Tong Y
Year: 2017
Journal: FEBS Lett
Title: An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome.
Volume: 591
Issue: 9
Pages: 1247-1257
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Publication
39745200 | J:360569
 
First Author: Trinh LT
Year: 2025
Journal: Development
Title: Positive autoregulation of Sox17 is necessary for gallbladder and extrahepatic bile duct formation.
Volume: 152
Issue: 2
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Publication
17328885 | J:122516
First Author: Sherwood RI
Year: 2007
Journal: Dev Biol
Title: Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Volume: 304
Issue: 2
Pages: 541-55
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Publication
35266581 | J:356554
First Author: Nahaboo W
Year: 2022
Journal: EMBO J
Title: Keratin filaments mediate the expansion of extra-embryonic membranes in the post-gastrulation mouse embryo.
Volume: 41
Issue: 7
Pages: e108747
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Publication
36543770 | J:332220
First Author: Uchida A
Year: 2022
Journal: Nat Commun
Title: SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse.
Volume: 13
Issue: 1
Pages: 7860
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Publication
36656901 | J:332969
First Author: Comerford SA
Year: 2023
Journal: PLoS Genet
Title: Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.
Volume: 19
Issue: 1
Pages: e1010595
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Publication
32597756 | J:294824
   
First Author: Dias A
Year: 2020
Journal: Elife
Title: A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.
Volume: 9
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Publication
27770432 | J:241728
First Author: Chao CM
Year: 2017
Journal: J Pathol
Title: Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia.
Volume: 241
Issue: 1
Pages: 91-103
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Publication
30566624 | J:273652
First Author: Chao CM
Year: 2019
Journal: Hum Mol Genet
Title: Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.
Volume: 28
Issue: 9
Pages: 1429-1444
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Publication
26764350 | J:232444
First Author: Li S
Year: 2016
Journal: Biol Reprod
Title: Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.
Volume: 94
Issue: 2
Pages: 41
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
17940847 | J:137740
First Author: Trzpis M
Year: 2008
Journal: Transgenic Res
Title: EpCAM homologues exhibit epithelial-specific but different expression patterns in the kidney.
Volume: 17
Issue: 2
Pages: 229-38
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Publication
30623107 | J:278023
 
First Author: Kawaguchi M
Year: 2019
Journal: Commun Biol
Title: Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine.
Volume: 2
Pages: 11
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Allele
Epcam<tm1(EPCAM)Smoc> | MGI:7263384
Name: epithelial cell adhesion molecule; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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HT Sample
GSM4484805
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484806
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484807
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484808
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484809
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484810
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: esophagus
Notes: Cells have been sorted on low expression of EpCam
Curation Status: Curated
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HT Sample
GSM4484823
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: esophagus
Notes: Cells have been sorted on EpCam and YFP expression
Curation Status: Curated
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HT Sample
GSM4484824
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 13.5
Stage: 21
Structure . Name: esophagus
Notes: Cells have been sorted on EpCam and YFP expression
Curation Status: Curated
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Allele
Epcam<em1(cre/ERT2)Smoc> | MGI:6430709
Name: epithelial cell adhesion molecule; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Strain
MGI:6770728 | C57BL/6JSmoc-Epcam<tm1(EPCAM)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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HT Sample
GSM4484825
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: stomach
Notes: Columnar part of the junction; cells have been sorted on high EpCam and YFP expression
Curation Status: Curated
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HT Sample
GSM4484826
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: stomach
Notes: Columnar part of the junction; cells have been sorted on high EpCam and YFP expression
Curation Status: Curated
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HT Sample
GSM4484827
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: stomach
Notes: Columnar part of the junction; cells have been sorted on high EpCam and YFP expression
Curation Status: Curated
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HT Sample
GSM4484828
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal
Stage: 28
Structure . Name: stomach
Notes: Columnar part of the junction; cells have been sorted on high EpCam and YFP expression
Curation Status: Curated
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Strain
MGI:6354763 | C57BL/6JSmoc-Epcam<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7751780 | C57BL/6JSmoc-Cd3e<em6(CD3E)Smoc> Epcam<tm1(EPCAM)>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7751761 | C57BL/6JSmoc-In(9CD3D,CD3E,CD3G)1Smoc Epcam<tm1(EPCAM)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Epcam<Gt(RST412)Byg> | MGI:4127340
Name: epithelial cell adhesion molecule; gene trap RST412, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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DO Term
DOID:0070270 | hereditary nonpolyposis colorectal cancer type 8
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Allele
Tg(Epcam-cre/ERT2)#Hmar | MGI:7437768
Name: transgene insertion, Hiroyuki Marusawa
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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CL Term
CL:4033057 | luminal adaptive secretory precursor cell of mammary gland
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Genotype
Genotype
Symbol: Epcam/Epcam
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0060776 | congenital diarrhea 5 with tufting enteropathy
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HT Experiment
GSE90969 | EMC3 conditional KO in developing lung epithelium
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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CL Term
CL:4033058 | luminal hormone-sensing cell of mammary gland
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HT Experiment
GSE154007 | Tracing colonic embryonic transcriptional programs and their reactivation in inflammatory disease at single cell level
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Protein
Q3U261
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
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Protein
Q8CG12
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Publication
31225512 | -
First Author: Keller L
Year: 2019
Journal: Cell Stress
Title: Biology and clinical relevance of EpCAM.
Volume: 3
Issue: 6
Pages: 165-180
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Publication
20651236 | -
First Author: Nakatsukasa M
Year: 2010
Journal: Am J Pathol
Title: Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy.
Volume: 177
Issue: 3
Pages: 1344-55
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Publication
18281513 | -
First Author: Wang J
Year: 2008
Journal: Mol Cancer Ther
Title: Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers.
Volume: 7
Issue: 2
Pages: 280-5
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Publication
31177095 | -
First Author: Mori Y
Year: 2019
Journal: J Biol Chem
Title: Trophoblast cell surface antigen 2 (Trop-2) phosphorylation by protein kinase C α/δ (PKCα/δ) enhances cell motility.
Volume: 294
Issue: 30
Pages: 11513-11524
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Publication
30628064 | -
First Author: Yahyazadeh Mashhadi SM
Year: 2019
Journal: J Cell Physiol
Title: Shedding light on the EpCAM: An overview.
Volume: 234
Issue: 8
Pages: 12569-12580
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Publication
23536555 | -
First Author: Trerotola M
Year: 2013
Journal: Cancer Res
Title: Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.
Volume: 73
Issue: 10
Pages: 3155-67
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Protein Domain
IPR043406 | EPCAM/Trop-2
Type: Family
Description: This entry includes transmembrane glycoprotein EpCAM (epithelial cell adhesion molecule, also known as Trop-1) and Trop-2 (also known as tumor-associated calcium signal transducer 2, TACSTD2). They belong to the tumour-associated calcium signal transducer (TACSTD) family. They have been reported to directly interact with claudin-1 and claudin-7 [, , ]. EpCAM mediates homotypic cell contacts in epithelia tissues and regulates cell proliferation and cancer stemness. It has been used as a diagnostic marker for circulating tumour cells (CTCs) in the blood []. EpCAM has been shown to contribute to formation of intestinal barrier by recruiting claudins to cell-cell junctions []. Mutations in the EpCAM gene lead to congenital tufting enteropathy, severe intestinal epithelium homeostasis disorders, and Lynch syndrome []. Trop-2 is highly expressed in a variety of epithelial cancer cells. It has been identified as an oncogene leading to invasiveness and tumorigenesis []. It has been shown to regulate integrin-dependent signalling for cell-substrate adhesion and cell migration. It also modulates Rac1 GTPase activity and induces activation of PAK4 [].
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HT Experiment
GSE13040 | E11.5 Mouse Endodermal Organ Gene Expression
Series Id: E-GEOD-13040
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: GEO
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HT Experiment
GSE210594 | Positional cues underlie cell fate specification during branching morphogenesis of the embryonic mammary epithelium
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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