Type |
Details |
Score |
Publication |
First Author: |
Geoghegan F |
Year: |
2017 |
Journal: |
J Dent Res |
Title: |
Vax1 Plays an Indirect Role in the Etiology of Murine Cleft Palate. |
Volume: |
96 |
Issue: |
13 |
Pages: |
1555-1562 |
|
•
•
•
•
•
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Publication |
First Author: |
Leung AOW |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1. |
Volume: |
15 |
Issue: |
1 |
Pages: |
2229 |
|
•
•
•
•
•
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Publication |
First Author: |
Cheng YS |
Year: |
2021 |
Journal: |
Nat Chem Biol |
Title: |
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes. |
Volume: |
17 |
Issue: |
12 |
Pages: |
1271-1280 |
|
•
•
•
•
•
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Publication |
First Author: |
Matsushita Y |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis. |
Volume: |
14 |
Issue: |
1 |
Pages: |
2383 |
|
•
•
•
•
•
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Publication |
First Author: |
Matt N |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis. |
Volume: |
320 |
Issue: |
1 |
Pages: |
140-8 |
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•
•
•
•
•
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Publication |
First Author: |
Raines AM |
Year: |
2015 |
Journal: |
BMC Dev Biol |
Title: |
Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development. |
Volume: |
15 |
|
Pages: |
28 |
|
•
•
•
•
•
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Publication |
First Author: |
Hussein MT |
Year: |
2021 |
Journal: |
Gene Expr Patterns |
Title: |
Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons. |
Volume: |
42 |
|
Pages: |
119217 |
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•
•
•
•
•
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Publication |
First Author: |
Allen BL |
Year: |
2011 |
Journal: |
Dev Cell |
Title: |
Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. |
Volume: |
20 |
Issue: |
6 |
Pages: |
775-87 |
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•
•
•
•
•
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Publication |
First Author: |
EchevarrÃa-Andino ML |
Year: |
2022 |
Journal: |
Dev Biol |
Title: |
CDON contributes to Hedgehog-dependent patterning and growth of the developing limb. |
Volume: |
493 |
|
Pages: |
1-11 |
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•
•
•
•
•
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Publication |
First Author: |
Xu H |
Year: |
2020 |
Journal: |
Hum Mol Genet |
Title: |
Tbx5 inhibits hedgehog signaling in determination of digit identity. |
Volume: |
29 |
Issue: |
9 |
Pages: |
1405-1416 |
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•
•
•
•
•
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Publication |
First Author: |
Blake GET |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker. |
Volume: |
12 |
Issue: |
1 |
Pages: |
3714 |
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•
•
•
•
•
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Publication |
First Author: |
Shin JO |
Year: |
2017 |
Journal: |
Int J Dev Biol |
Title: |
Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear. |
Volume: |
61 |
Issue: |
8-9 |
Pages: |
557-563 |
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•
•
•
•
•
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Publication |
First Author: |
Junker JP |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. |
Volume: |
31 |
Issue: |
4 |
Pages: |
448-60 |
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•
•
•
•
•
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Publication |
First Author: |
Ikeda Y |
Year: |
2017 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Fgfr2 is integral for bladder mesenchyme patterning and function. |
Volume: |
312 |
Issue: |
4 |
Pages: |
F607-F618 |
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•
•
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•
•
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Publication |
First Author: |
Osterwalder M |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme. |
Volume: |
31 |
Issue: |
3 |
Pages: |
345-357 |
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•
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•
•
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Publication |
First Author: |
Colombo MP |
Year: |
1992 |
Journal: |
Mamm Genome |
Title: |
Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16. |
Volume: |
2 |
Issue: |
2 |
Pages: |
130-4 |
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•
•
•
•
•
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Publication |
First Author: |
Tamamura Y |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification. |
Volume: |
280 |
Issue: |
19 |
Pages: |
19185-95 |
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•
•
•
•
•
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Publication |
First Author: |
Rowan S |
Year: |
2004 |
Journal: |
Development |
Title: |
Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. |
Volume: |
131 |
Issue: |
20 |
Pages: |
5139-52 |
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•
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Publication |
First Author: |
Christ A |
Year: |
2015 |
Journal: |
Dev Cell |
Title: |
LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. |
Volume: |
35 |
Issue: |
1 |
Pages: |
36-48 |
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•
•
•
•
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Publication |
First Author: |
Okuhara S |
Year: |
2019 |
Journal: |
Development |
Title: |
Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature. |
Volume: |
146 |
Issue: |
21 |
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•
•
•
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Publication |
First Author: |
Woods L |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Decidualisation and placentation defects are a major cause of age-related reproductive decline. |
Volume: |
8 |
Issue: |
1 |
Pages: |
352 |
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•
•
•
•
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Publication |
First Author: |
Ramirez M |
Year: |
2022 |
Journal: |
Elife |
Title: |
Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions. |
Volume: |
11 |
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•
•
•
•
•
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Publication |
First Author: |
Decaens T |
Year: |
2008 |
Journal: |
Hepatology |
Title: |
Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. |
Volume: |
47 |
Issue: |
1 |
Pages: |
247-58 |
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•
•
•
•
•
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Publication |
First Author: |
Sandberg M |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. |
Volume: |
91 |
Issue: |
6 |
Pages: |
1260-1275 |
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•
•
•
•
•
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Publication |
First Author: |
Trimarchi JM |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. |
Volume: |
238 |
Issue: |
9 |
Pages: |
2327-9 |
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Publication |
First Author: |
Gibson P |
Year: |
2010 |
Journal: |
Nature |
Title: |
Subtypes of medulloblastoma have distinct developmental origins. |
Volume: |
468 |
Issue: |
7327 |
Pages: |
1095-9 |
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Publication |
First Author: |
Machold R |
Year: |
2011 |
Journal: |
Gene Expr Patterns |
Title: |
Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. |
Volume: |
11 |
Issue: |
5-6 |
Pages: |
349-59 |
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•
•
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•
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Publication |
First Author: |
Gurdziel K |
Year: |
2016 |
Journal: |
Dev Dyn |
Title: |
Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. |
Volume: |
245 |
Issue: |
5 |
Pages: |
614-26 |
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Publication |
First Author: |
Loo L |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Single-cell transcriptomic analysis of mouse neocortical development. |
Volume: |
10 |
Issue: |
1 |
Pages: |
134 |
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Publication |
First Author: |
Memic F |
Year: |
2018 |
Journal: |
Gastroenterology |
Title: |
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. |
Volume: |
154 |
Issue: |
3 |
Pages: |
624-636 |
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Publication |
First Author: |
Hoffman BG |
Year: |
2008 |
Journal: |
Genome Biol |
Title: |
Identification of transcripts with enriched expression in the developing and adult pancreas. |
Volume: |
9 |
Issue: |
6 |
Pages: |
R99 |
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Publication |
First Author: |
Freeman TC |
Year: |
1998 |
Journal: |
MGI Direct Data Submission |
Title: |
Expression Mapping of Mouse Genes |
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•
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Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
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Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
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Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
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•
•
•
•
•
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Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
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First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
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Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
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Pages: |
686034 |
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Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
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Pages: |
e86 |
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First Author: |
GemPharmatech |
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2020 |
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GemPharmatech Website. |
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First Author: |
Cyagen Biosciences Inc. |
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Title: |
Cyagen Biosciences Website. |
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First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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First Author: |
Koch MR |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The glucanosyltransferase Gas1 functions in transcriptional silencing. |
Volume: |
106 |
Issue: |
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Pages: |
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First Author: |
Cabrera JR |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling. |
Volume: |
281 |
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First Author: |
Nuoffer C |
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Journal: |
Mol Cell Biol |
Title: |
Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. |
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Eustice M |
Year: |
2014 |
Journal: |
Genetics |
Title: |
Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. |
Volume: |
196 |
Issue: |
4 |
Pages: |
1029-39 |
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•
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Allele |
Name: |
transgene insertion JT116, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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•
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•
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Strain |
Attribute String: |
mutant stock, transgenic |
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•
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Protein Domain |
Type: |
Domain |
Description: |
This cysteine rich domain is found in multiple copies in GNDF and GAS1 proteins. GDNF and neurturin (NTN) receptors are potent survival factors for sympathetic, sensory and central nervous system neurons [, ]. GDNF and neurturin promote neuronal survival by signalling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity []. |
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Year: |
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Journal: |
Nature |
Title: |
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor. |
Volume: |
387 |
Issue: |
6634 |
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First Author: |
Buj-Bello A |
Year: |
1997 |
Journal: |
Nature |
Title: |
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. |
Volume: |
387 |
Issue: |
6634 |
Pages: |
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Cowled PA |
Year: |
1994 |
Journal: |
Exp Cell Res |
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Expression of growth arrest-specific (gas) genes in senescent murine cells. |
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First Author: |
Baladrón V |
Year: |
2002 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system. |
Volume: |
291 |
Issue: |
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Pages: |
193-204 |
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Publication |
First Author: |
Miletich I |
Year: |
2005 |
Journal: |
Arch Oral Biol |
Title: |
Expression of the Hedgehog antagonists Rab23 and Slimb/betaTrCP during mouse tooth development. |
Volume: |
50 |
Issue: |
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Pages: |
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Publication |
First Author: |
Khan M |
Year: |
2007 |
Journal: |
Gene Expr Patterns |
Title: |
Hedgehog pathway gene expression during early development of the molar tooth root in the mouse. |
Volume: |
7 |
Issue: |
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Gurung B |
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2013 |
Journal: |
Cancer Res |
Title: |
Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. |
Volume: |
73 |
Issue: |
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First Author: |
Mallakin A |
Year: |
2010 |
Journal: |
Int J Cancer |
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The Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1. |
Volume: |
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Witt RM |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. |
Volume: |
288 |
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26275-88 |
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Jeong MH |
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2016 |
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J Mol Cell Cardiol |
Title: |
A Shh coreceptor Cdo is required for efficient cardiomyogenesis of pluripotent stem cells. |
Volume: |
93 |
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Pages: |
57-66 |
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Publication |
First Author: |
McLellan JS |
Year: |
2008 |
Journal: |
Nature |
Title: |
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. |
Volume: |
455 |
Issue: |
7215 |
Pages: |
979-83 |
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Publication |
First Author: |
Caporali A |
Year: |
2004 |
Journal: |
Carcinogenesis |
Title: |
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression. |
Volume: |
25 |
Issue: |
11 |
Pages: |
2217-24 |
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Publication |
First Author: |
Li H |
Year: |
1999 |
Journal: |
Dev Biol |
Title: |
Novel strategy yields candidate Gsh-1 homeobox gene targets using hypothalamus progenitor cell lines. |
Volume: |
211 |
Issue: |
1 |
Pages: |
64-76 |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
260
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
393
 |
Fragment?: |
false |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
301
 |
Fragment?: |
true |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
302
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
300
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
225
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
397
 |
Fragment?: |
false |
|
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
246
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
309
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
385
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
468
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
464
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
468
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
419
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
425
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
478
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
false |
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•
•
•
•
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Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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