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Search results 701 to 800 out of 825 for Hnf1b

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Type Details Score
Publication
31308417 | J:286691
First Author: Perea-Gomez A
Year: 2019
Journal: Sci Rep
Title: Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.
Volume: 9
Issue: 1
Pages: 10168
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Publication
27993987 | J:238418
First Author: Yang YP
Year: 2017
Journal: Development
Title: The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Volume: 144
Issue: 2
Pages: 248-257
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Publication
19403103 | J:150973
First Author: Antoniou A
Year: 2009
Journal: Gastroenterology
Title: Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9.
Volume: 136
Issue: 7
Pages: 2325-33
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Publication
19369401 | J:148015
First Author: Zong Y
Year: 2009
Journal: Development
Title: Notch signaling controls liver development by regulating biliary differentiation.
Volume: 136
Issue: 10
Pages: 1727-39
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Publication
25446530 | J:218171
First Author: Falix FA
Year: 2014
Journal: Dev Biol
Title: Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
Volume: 396
Issue: 2
Pages: 201-13
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Publication
26033091 | J:224392
First Author: Poncy A
Year: 2015
Journal: Dev Biol
Title: Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.
Volume: 404
Issue: 2
Pages: 136-48
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Publication
25715394 | J:220325
First Author: Lemaire LA
Year: 2015
Journal: Development
Title: Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.
Volume: 142
Issue: 5
Pages: 858-70
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Publication
22675211 | J:185601
First Author: Shih HP
Year: 2012
Journal: Development
Title: A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Volume: 139
Issue: 14
Pages: 2488-99
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Publication
31875961 | J:291600
First Author: Rodríguez-Seguel E
Year: 2020
Journal: J Pathol
Title: Loss of GATA4 causes ectopic pancreas in the stomach.
Volume: 250
Issue: 4
Pages: 362-373
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Publication
30487608 | J:267771
First Author: Mamidi A
Year: 2018
Journal: Nature
Title: Mechanosignalling via integrins directs fate decisions of pancreatic progenitors.
Volume: 564
Issue: 7734
Pages: 114-118
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Publication
23554936 | J:199892
First Author: Rhee S
Year: 2013
Journal: PLoS One
Title: Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.
Volume: 8
Issue: 3
Pages: e58828
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Publication
27582005 | J:235788
First Author: Nagy II
Year: 2016
Journal: BMC Dev Biol
Title: Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.
Volume: 16
Issue: 1
Pages: 30
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Publication
34433966 | J:325905
First Author: Willnow D
Year: 2021
Journal: Nature
Title: Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Volume: 597
Issue: 7874
Pages: 87-91
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Publication
25576928 | J:219809
First Author: Afelik S
Year: 2015
Journal: Dev Biol
Title: Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development.
Volume: 399
Issue: 2
Pages: 204-17
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Publication
37963393 | J:357466
First Author: Sun J
Year: 2024
Journal: Diabetes
Title: Mettl3-Mediated m6A Methylation Controls Pancreatic Bipotent Progenitor Fate and Islet Formation.
Volume: 73
Issue: 2
Pages: 237-249
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Publication
23852729 | J:198781
First Author: Sugiyama T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Volume: 110
Issue: 31
Pages: 12691-6
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Publication
17251353 | J:119488
First Author: Hossain Z
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Volume: 104
Issue: 5
Pages: 1631-6
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Publication
29712641 | J:264112
 
First Author: Liu H
Year: 2018
Journal: Development
Title: Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles.
Volume: 145
Issue: 10
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Publication
29449451 | J:296649
First Author: Lindström NO
Year: 2018
Journal: J Am Soc Nephrol
Title: Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.
Volume: 29
Issue: 3
Pages: 825-840
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Publication
21786021 | J:177082
First Author: Yang Y
Year: 2011
Journal: Diabetologia
Title: The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.
Volume: 54
Issue: 10
Pages: 2595-605
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Publication
31524221 | J:282241
First Author: Yang Y
Year: 2019
Journal: Int J Mol Med
Title: Circular RNA profile in liver tissue of EpCAM knockout mice.
Volume: 44
Issue: 3
Pages: 1063-1077
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Publication
18778483 | J:142415
 
First Author: Hoffman BG
Year: 2008
Journal: BMC Dev Biol
Title: Expression of Groucho/TLE proteins during pancreas development.
Volume: 8
Pages: 81
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Publication
36656901 | J:332969
First Author: Comerford SA
Year: 2023
Journal: PLoS Genet
Title: Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.
Volume: 19
Issue: 1
Pages: e1010595
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Publication
18346943 | J:133949
First Author: Valerius MT
Year: 2008
Journal: Gene Expr Patterns
Title: Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation.
Volume: 8
Issue: 5
Pages: 297-306
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Publication
18038450 | J:243698
First Author: Decaens T
Year: 2008
Journal: Hepatology
Title: Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.
Volume: 47
Issue: 1
Pages: 247-58
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Publication
23684747 | J:315740
First Author: Prévot PP
Year: 2013
Journal: Gastroenterology
Title: Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.
Volume: 145
Issue: 3
Pages: 668-78.e3
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Publication
25063451 | J:214089
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33
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Publication
23177622 | J:269131
First Author: Cortijo C
Year: 2012
Journal: Cell Rep
Title: Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.
Volume: 2
Issue: 6
Pages: 1593-606
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Publication
30590051 | J:271120
First Author: Scavuzzo MA
Year: 2018
Journal: Cell Rep
Title: Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
Volume: 25
Issue: 13
Pages: 3811-3827.e7
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Publication
27820600 | J:238554
First Author: Kaminski MM
Year: 2016
Journal: Nat Cell Biol
Title: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Volume: 18
Issue: 12
Pages: 1269-1280
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Publication
26771085 | J:251520
 
First Author: Pujadas G
Year: 2016
Journal: Sci Rep
Title: Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.
Volume: 6
Pages: 19223
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Publication
29459093 | J:309384
First Author: Neirijnck Y
Year: 2018
Journal: Kidney Int
Title: Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).
Volume: 93
Issue: 5
Pages: 1142-1153
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Publication
18356246 | J:134487
First Author: Suzuki A
Year: 2008
Journal: Development
Title: Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.
Volume: 135
Issue: 9
Pages: 1589-95
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Publication
18974875 | J:147414
First Author: Landry J
Year: 2008
Journal: PLoS Genet
Title: Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.
Volume: 4
Issue: 10
Pages: e1000241
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Publication
38191655 | J:344186
First Author: Muñoz-Gallardo MDM
Year: 2024
Journal: Sci Rep
Title: miR-195b is required for proper cellular homeostasis in the elderly.
Volume: 14
Issue: 1
Pages: 810
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Publication
24449835 | J:208341
First Author: Seth A
Year: 2014
Journal: Development
Title: Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.
Volume: 141
Issue: 3
Pages: 538-47
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Publication
29798841 | J:277787
First Author: Ikuta K
Year: 2019
Journal: Gut
Title: Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.
Volume: 68
Issue: 5
Pages: 882-892
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Publication
23555292 | J:195266
First Author: Reginensi A
Year: 2013
Journal: PLoS Genet
Title: Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development.
Volume: 9
Issue: 3
Pages: e1003380
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Publication
31323030 | J:279716
First Author: Braitsch CM
Year: 2019
Journal: PLoS Biol
Title: LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.
Volume: 17
Issue: 7
Pages: e3000382
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Publication
35729116 | J:326354
First Author: Allègre N
Year: 2022
Journal: Nat Commun
Title: NANOG initiates epiblast fate through the coordination of pluripotency genes expression.
Volume: 13
Issue: 1
Pages: 3550
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Publication
21525287 | J:171421
First Author: VanDunk C
Year: 2011
Journal: J Neurosci
Title: Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.
Volume: 31
Issue: 17
Pages: 6457-67
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Publication
26450967 | J:239872
First Author: Larsen BM
Year: 2015
Journal: Development
Title: Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.
Volume: 142
Issue: 22
Pages: 3859-68
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Publication
22711520 | J:186535
First Author: Herriges JC
Year: 2012
Journal: Dev Dyn
Title: Genome-scale study of transcription factor expression in the branching mouse lung.
Volume: 241
Issue: 9
Pages: 1432-53
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Publication
20843830 | J:166958
First Author: Yates LL
Year: 2010
Journal: Hum Mol Genet
Title: The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
Volume: 19
Issue: 23
Pages: 4663-76
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Publication
17609113 | J:123923
First Author: Zhou Q
Year: 2007
Journal: Dev Cell
Title: A multipotent progenitor domain guides pancreatic organogenesis.
Volume: 13
Issue: 1
Pages: 103-14
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE106085 | HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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DO Term
DOID:0111101 | maturity-onset diabetes of the young type 5
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HT Experiment
GSE159566 | mRNA sequencing of embryonic kidney at different stages from wild-type and heterozygous mutants of a novel mouse model carrying a human splicing point-mutation in the Hnf1b-gene
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Del(11Hnf1b-Znhit3)11Moro | MGI:7490277
Name: deletion, Chr 11, Eric Morrow
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7490279 | STOCK Del(11Hnf1b-Znhit3)11Moro/Mmjax
Attribute String: deletion, mutant stock
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Publication
36373506 | J:334297
 
First Author: Warren EB
Year: 2022
Journal: Dis Model Mech
Title: 17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasis.
Volume: 15
Issue: 12
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Publication
29289465 | -
First Author: Naqvi AAT
Year: 2018
Journal: Pancreatology
Title: Investigating the role of transcription factors of pancreas development in pancreatic cancer.
Volume: 18
Issue: 2
Pages: 184-190
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Publication
1677179 | -
First Author: Bach I
Year: 1991
Journal: Nucleic Acids Res
Title: Two members of an HNF1 homeoprotein family are expressed in human liver.
Volume: 19
Issue: 13
Pages: 3553-9
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Publication
26855178 | -
First Author: Yang R
Year: 2016
Journal: Biochim Biophys Acta
Title: Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.
Volume: 1859
Issue: 4
Pages: 591-8
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Protein Domain
IPR039066 | HNF-1
Type: Family
Description: Hepatocyte nuclear factor 1-alpha (HNF1A, TCF1) and hepatocyte nuclear factor 1-beta (HNF1B, TCF2) are homeodomain-containing transcription factors expressed in the pancreas, liver, kidney, and intestine, where they direct tissue-specific gene regulation [, ]. They play an essential role in the development and differentiation of pancreatic precursor cells [, ]. Mutations in HNF1beta and HNF1alpha cause autosomal dominant diabetes maturity-onset diabetes of the young (MODY), which is a monogenic form of non-insulin-dependent type 2 diabetes. Mutations in HNF1A are responsible for type 3 MODY (MODY3) [], whereas the HNF1B gene is linked to a rare case of type 5 MODY (MODY5) [].
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Allele
Tg(Hnf1b-cre/ERT2)1Jfer | MGI:4420452
Name: transgene insertion 1, Jorge Ferrer
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Publication
30092080 | J:264355
First Author: Vieira A
Year: 2018
Journal: PLoS One
Title: Neurog3 misexpression unravels mouse pancreatic ductal cell plasticity.
Volume: 13
Issue: 8
Pages: e0201536
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Strain
MGI:5638413 | STOCK Tg(Hnf1b-cre/ERT2)1Jfer/J
Attribute String: mutant stock, transgenic
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Publication
16917892 | -
First Author: Ellard S
Year: 2006
Journal: Hum Mutat
Title: Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young.
Volume: 27
Issue: 9
Pages: 854-69
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Publication
11463573 | -
First Author: Ryffel GU
Year: 2001
Journal: J Mol Endocrinol
Title: Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences.
Volume: 27
Issue: 1
Pages: 11-29
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17923767 | -
 
First Author: Maestro MA
Year: 2007
Journal: Endocr Dev
Title: Distinct roles of HNF1beta, HNF1alpha, and HNF4alpha in regulating pancreas development, beta-cell function and growth.
Volume: 12
Pages: 33-45
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26592447 | J:228016
First Author: Bailey JM
Year: 2016
Journal: Oncogene
Title: p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells.
Volume: 35
Issue: 32
Pages: 4282-8
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32843721 | J:296226
First Author: Wang X
Year: 2020
Journal: Oncogene
Title: Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
Volume: 39
Issue: 40
Pages: 6286-6299
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Publication
35460694 | J:347005
First Author: Mostofa MG
Year: 2022
Journal: J Biol Chem
Title: MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease.
Volume: 298
Issue: 6
Pages: 101966
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Publication
28622294 | J:268205
First Author: Wang X
Year: 2017
Journal: Cell Death Differ
Title: Hepatocyte nuclear factor 1b is a novel negative regulator of white adipocyte differentiation.
Volume: 24
Issue: 9
Pages: 1588-1597
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38529500 | J:360833
     
First Author: Jankowski J
Year: 2024
Journal: bioRxiv
Title: Sexually dimorphic renal expression of Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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