|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 701 to 800 out of 818 for Hoxa9

0.044s
Type Details Score
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Nakamura T
Year: 1996
Journal: Nat Genet
Title: Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.
Volume: 12
Issue: 2
Pages: 154-8
Publication
First Author: Quéré R
Year: 2011
Journal: Blood
Title: Smad4 binds Hoxa9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by Hoxa9 and leukemia transformation.
Volume: 117
Issue: 22
Pages: 5918-30
Publication
First Author: Mohr S
Year: 2017
Journal: Cancer Cell
Title: Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
Volume: 31
Issue: 4
Pages: 549-562.e11
Publication
First Author: Thorsteinsdottir U
Year: 2002
Journal: Blood
Title: Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion.
Volume: 99
Issue: 1
Pages: 121-9
Interaction Experiment
Description: A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the typical Hoxa9 protein during embryogenesis.
Publication
First Author: Ye S
Year: 2023
Journal: Theranostics
Title: DNA hypermethylation-induced miR-182 silence targets BCL2 and HOXA9 to facilitate the self-renewal of leukemia stem cell, accelerate acute myeloid leukemia progression, and determine the sensitivity of BCL2 inhibitor venetoclax.
Volume: 13
Issue: 1
Pages: 77-94
Interaction Experiment
Description: Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.
Publication
First Author: Bandyopadhyay S
Year: 2012
Journal: Mol Cell Biol
Title: HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules.
Volume: 32
Issue: 7
Pages: 1202-13
Publication
First Author: Topisirovic I
Year: 2005
Journal: Mol Cell Biol
Title: Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.
Volume: 25
Issue: 3
Pages: 1100-12
Interaction Experiment
Description: Scmh1 has E3 ubiquitin ligase activity for Geminin and histone H2A and regulates Geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4.
Publication
First Author: Iwasaki M
Year: 2005
Journal: Blood
Title: Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model.
Volume: 105
Issue: 2
Pages: 784-93
Allele
Name: homeobox A cluster; targeted mutation 1.1, S Steven Potter
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: homeobox A cluster; targeted mutation 2.1, S Steven Potter
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Hoxa/Hoxa
Background: involves: 129 * CD-1
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: He C
Year: 2013
Journal: J Biol Chem
Title: The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
Volume: 288
Issue: 7
Pages: 4692-703
Protein Domain
Type: Domain
Description: This is an NSD-specific Cys-His rich region (C5HCH) domain. Proteins containing this domain include NSD (nuclear receptor SET domain-containing) proteins. This domain is located on the C-terminal of NSD1, 2 and 3 proteins. C5HCH domain lies adjacent to the fifth plant homeodomain (PHD5). The PHD5-C5HCH module of NSD3 (PHD5-C5HCHNSD3) recognises the H3 N-terminal peptide containing unmodified K4 and trimethylated K9. Moreover, it has been reported that the PHD5-C5HCH module of NSD1 (PHD5-C5HCH) was the sole region required for tight binding of the NUP98-NSD1 fusion protein to the HoxA9 gene promoter, implicating that PHD5-C5HCH might have chromatin targeting ability [].
Allele
Name: transgene insertion 1589, Takuro Nakamura
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: mutant strain, congenic, transgenic
Publication
First Author: Grisolano JL
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice.
Volume: 91
Issue: 19
Pages: 8989-93
Publication
First Author: Funasaka T
Year: 2011
Journal: Cell Cycle
Title: RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.
Volume: 10
Issue: 9
Pages: 1456-67
Publication
First Author: Magella B
Year: 2018
Journal: Dev Biol
Title: Reduced Abd-B Hox function during kidney development results in lineage infidelity.
Volume: 438
Issue: 2
Pages: 84-93
Publication  
First Author: Raines AM
Year: 2015
Journal: BMC Dev Biol
Title: Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development.
Volume: 15
Pages: 28
Genotype
Symbol: Hoxa/Hoxa<+> Hoxd/Hoxd
Background: involves: 129 * CD-1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa Hoxd/Hoxd
Background: involves: 129 * CD-1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa<+> Hoxd/Hoxd<+>
Background: involves: 129 * CD-1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa Hoxd/Hoxd<+>
Background: involves: 129 * CD-1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa Hoxc/Hoxc
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa<+> Hoxc/Hoxc
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa Hoxc/Hoxc<+>
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Sun M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
Volume: 110
Issue: 24
Pages: 9920-5
Publication
First Author: Wang Y
Year: 2010
Journal: Science
Title: The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
Volume: 327
Issue: 5973
Pages: 1650-3
Publication
First Author: Eifert T
Year: 2023
Journal: Leukemia
Title: Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.
Volume: 37
Issue: 10
Pages: 2027-2035
Publication
First Author: Zhu N
Year: 2016
Journal: J Clin Invest
Title: MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.
Volume: 126
Issue: 3
Pages: 997-1011
Publication
First Author: Saha N
Year: 2019
Journal: Stem Cell Reports
Title: The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation.
Volume: 12
Issue: 5
Pages: 1069-1083
Publication
First Author: Lebert-Ghali CÉ
Year: 2016
Journal: Blood
Title: Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.
Volume: 127
Issue: 1
Pages: 87-90
Publication
First Author: Sykes DB
Year: 2016
Journal: Cell
Title: Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Volume: 167
Issue: 1
Pages: 171-186.e15
Publication
First Author: Mouw JK
Year: 2014
Journal: Nat Med
Title: Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.
Volume: 20
Issue: 4
Pages: 360-7
Publication
First Author: Zhao J
Year: 2021
Journal: iScience
Title: TIFAB accelerates MLL-AF9-Induced acute myeloid leukemia through upregulation of HOXA9.
Volume: 24
Issue: 12
Pages: 103425
Publication
First Author: Kats LM
Year: 2014
Journal: Cell Stem Cell
Title: Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance.
Volume: 14
Issue: 3
Pages: 329-41
Publication
First Author: Singh SK
Year: 2013
Journal: J Exp Med
Title: Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.
Volume: 210
Issue: 5
Pages: 987-1001
Publication
First Author: Park SM
Year: 2019
Journal: Cell Stem Cell
Title: IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Volume: 24
Issue: 1
Pages: 153-165.e7
Publication
First Author: Somerville TD
Year: 2015
Journal: Cancer Cell
Title: Frequent Derepression of the Mesenchymal Transcription Factor Gene FOXC1 in Acute Myeloid Leukemia.
Volume: 28
Issue: 3
Pages: 329-42
Publication
First Author: Okada Y
Year: 2005
Journal: Cell
Title: hDOT1L links histone methylation to leukemogenesis.
Volume: 121
Issue: 2
Pages: 167-78
Publication
First Author: Kroon E
Year: 2001
Journal: EMBO J
Title: NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice.
Volume: 20
Issue: 3
Pages: 350-61
Publication
First Author: Liu T
Year: 2018
Journal: Cell Death Dis
Title: The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells.
Volume: 9
Issue: 6
Pages: 677
Publication
First Author: Velu CS
Year: 2014
Journal: J Clin Invest
Title: Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
Volume: 124
Issue: 1
Pages: 222-36
Publication
First Author: Drake KA
Year: 2018
Journal: Sci Rep
Title: Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney.
Volume: 8
Issue: 1
Pages: 6306
Genotype
Symbol: Hoxa/Hoxa<+> Hoxc/Hoxc<+> Hoxd/Hoxd<+>
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Hoxa/Hoxa<+> Hoxc/Hoxc<+> Hoxd/Hoxd<+>
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Mucenski ML
Year: 2019
Journal: Sci Rep
Title: Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus.
Volume: 9
Issue: 1
Pages: 4557
Publication
First Author: Chen YX
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.
Volume: 103
Issue: 4
Pages: 1018-23
Publication
First Author: MacPherson L
Year: 2020
Journal: Nature
Title: HBO1 is required for the maintenance of leukaemia stem cells.
Volume: 577
Issue: 7789
Pages: 266-270
Publication
First Author: Riedel SS
Year: 2016
Journal: J Clin Invest
Title: MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Volume: 126
Issue: 4
Pages: 1438-50
Publication
First Author: Segditsas S
Year: 2008
Journal: Hum Mol Genet
Title: Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.
Volume: 17
Issue: 24
Pages: 3864-75
Publication
First Author: Trigueros-Motos L
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Embryological-origin-dependent differences in homeobox expression in adult aorta: role in regional phenotypic variability and regulation of NF-κB activity.
Volume: 33
Issue: 6
Pages: 1248-56
Publication
First Author: Baratono SR
Year: 2015
Journal: Eur J Immunol
Title: Toll-like receptor 9 and interferon-γ receptor signaling suppress the B-cell fate of uncommitted progenitors in mice.
Volume: 45
Issue: 5
Pages: 1313-25
Publication
First Author: Rossi A
Year: 2016
Journal: Sci Adv
Title: Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice.
Volume: 2
Issue: 10
Pages: e1600972
Publication
First Author: Di-Poï N
Year: 2010
Journal: Dev Biol
Title: Additive and global functions of HoxA cluster genes in mesoderm derivatives.
Volume: 341
Issue: 2
Pages: 488-98
Publication
First Author: Maillard I
Year: 2009
Journal: Blood
Title: Menin regulates the function of hematopoietic stem cells and lymphoid progenitors.
Volume: 113
Issue: 8
Pages: 1661-9
Publication
First Author: Li BE
Year: 2013
Journal: Blood
Title: Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.
Volume: 122
Issue: 12
Pages: 2039-46
Publication
First Author: Sprüssel A
Year: 2012
Journal: Leukemia
Title: Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Volume: 26
Issue: 9
Pages: 2039-51
Publication
First Author: Hisa T
Year: 2004
Journal: EMBO J
Title: Hematopoietic, angiogenic and eye defects in Meis1 mutant animals.
Volume: 23
Issue: 2
Pages: 450-9
Publication
First Author: Khandanpour C
Year: 2011
Journal: Stem Cells
Title: Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.
Volume: 29
Issue: 2
Pages: 376-85
Publication
First Author: Kawagoe H
Year: 2005
Journal: Blood
Title: Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9.
Volume: 106
Issue: 13
Pages: 4269-77
Publication
First Author: Yokoyama T
Year: 2016
Journal: J Clin Invest
Title: MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Volume: 126
Issue: 5
Pages: 1664-78
Publication
First Author: El Ashkar S
Year: 2018
Journal: Blood
Title: LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.
Volume: 131
Issue: 1
Pages: 95-107
Publication
First Author: Shinoda D
Year: 2022
Journal: Leukemia
Title: Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis.
Volume: 36
Issue: 2
Pages: 452-463
Publication
First Author: Li A
Year: 2013
Journal: J Clin Invest
Title: A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis.
Volume: 123
Issue: 10
Pages: 4195-207
Publication
First Author: Yoshino S
Year: 2021
Journal: Blood
Title: Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9.
Volume: 137
Issue: 1
Pages: 75-88
Publication
First Author: Inoue D
Year: 2013
Journal: J Clin Invest
Title: Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations.
Volume: 123
Issue: 11
Pages: 4627-40
Publication
First Author: Patel CV
Year: 1999
Journal: J Biol Chem
Title: Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9.
Volume: 274
Issue: 3
Pages: 1415-22