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Search results 701 to 800 out of 962 for Igf1r

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Type Details Score
Publication
19164599 | J:147173
First Author: Sultana DA
Year: 2009
Journal: Blood
Title: Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development.
Volume: 113
Issue: 13
Pages: 2976-87
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
35084365 | J:326026
First Author: Prokopuk L
Year: 2022
Journal: Reproduction
Title: An essential role for Polycomb Repressive Complex 2 in the mouse ovary.
Volume: 163
Issue: 3
Pages: 167-182
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Publication
11114734 | J:66153
First Author: Robinson DR
Year: 2000
Journal: Oncogene
Title: The protein tyrosine kinase family of the human genome.
Volume: 19
Issue: 49
Pages: 5548-57
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Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
29688375 | J:250512
   
First Author: Li J
Year: 2018
Journal: Database (Oxford)
Title: CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.
Volume: 2018
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Publication
26238476 | J:226028
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
29031500 | J:257654
First Author: Memic F
Year: 2018
Journal: Gastroenterology
Title: Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.
Volume: 154
Issue: 3
Pages: 624-636
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE88836 | Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role During Repair Kinetics after Selective Club Cell Ablation
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
7587382 | J:29703
First Author: Lahbib-Mansais Y
Year: 1995
Journal: Cytogenet Cell Genet
Title: Localization of IGF1R and EDN genes to pig chromosomes 1 and 7 by in situ hybridization.
Volume: 71
Issue: 3
Pages: 225-7
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HT Experiment
GSE85329 | Olfactory sensory neuron-specific IGF1R knockout in mice results in increased smell perception, insulin resistance and adiposity
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
31235784 | J:279337
First Author: Zhu S
Year: 2019
Journal: Oncogene
Title: Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells.
Volume: 38
Issue: 29
Pages: 5805-5816
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Publication
38565402 | J:360177
     
First Author: Chen Y
Year: 2024
Journal: J Adv Res
Title: Exercise-Induced Reduction of IGF1R Sumoylation Attenuates Neuroinflammation in APP/PS1 Transgenic Mice.
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Publication
25885794 | J:224638
First Author: Cookman CJ
Year: 2015
Journal: Endocrinology
Title: Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
Volume: 156
Issue: 7
Pages: 2395-408
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Publication
31010847 | J:280061
First Author: Scheffold A
Year: 2019
Journal: Blood
Title: IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Volume: 134
Issue: 6
Pages: 534-547
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Publication
32376245 | J:290713
First Author: Farabaugh SM
Year: 2020
Journal: Dev Biol
Title: IGF1R constitutive activation expands luminal progenitors and influences lineage differentiation during breast tumorigenesis.
Volume: 463
Issue: 1
Pages: 77-87
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Publication
23658296 | J:200542
First Author: Chen R
Year: 2013
Journal: Cancer Discov
Title: Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 491-3
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Publication
15752742 | J:97454
First Author: Shiura H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades.
Volume: 329
Issue: 3
Pages: 909-16
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Pathway
R-MMU-2428924 | IGF1R signaling cascade
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Publication
37686596 | J:340318
 
First Author: Bustamante-Marin X
Year: 2023
Journal: Cancers (Basel)
Title: Regulation of IGF1R by MicroRNA-15b Contributes to the Anticancer Effects of Calorie Restriction in a Murine C3-TAg Model of Triple-Negative Breast Cancer.
Volume: 15
Issue: 17
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Pathway
R-MMU-2428928 | IRS-related events triggered by IGF1R
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Pathway
R-MMU-2428933 | SHC-related events triggered by IGF1R
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Interaction Experiment
Yang C (2020)
Description: Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers.
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Publication
22261717 | -
First Author: Warsito D
Year: 2012
Journal: EMBO Rep
Title: Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF.
Volume: 13
Issue: 3
Pages: 244-50
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Allele
Igf1r<em2Smoc> | MGI:7290355
Name: insulin-like growth factor I receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Igf1r<tm2(IGF1R)Smoc> | MGI:7786877
Name: insulin-like growth factor I receptor; targeted mutation 2, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6770838 | C57BL/6JSmoc-Igf1r<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7788714 | C57BL/6JSmoc-Igf1r<tm2(IGF1R)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
32701997 | -
First Author: Yang C
Year: 2020
Journal: PLoS One
Title: Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers.
Volume: 15
Issue: 7
Pages: e0236291
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Allele
Igf1r<em1Smoc> | MGI:7290354
Name: insulin-like growth factor I receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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GO Term
GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex
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Protein Coding Gene
MGI:1338009 | Irs4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9Z0Y7
Organism: Mus musculus/domesticus
Length: 1216  
Fragment?: false
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Allele
Igf1r<hyft> | MGI:3576029
 
Name: insulin-like growth factor I receptor; hydrops fetalis
Allele Type: Chemically induced (ENU)
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Allele
Tg(Myh6-IGF1R)7Jmcm | MGI:3630255
Name: transgene insertion 7, Julie R McMullen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(tetO-IGF1R)1Ramo | MGI:5432255
Name: transgene insertion 1, Roger A Moorehead
Allele Type: Transgenic
Attribute String: Humanized sequence, Inducible, Inserted expressed sequence
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Strain
MGI:6475549 | C57BL/6JSmoc-Igf1r<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein
Q60751
Organism: Mus musculus/domesticus
Length: 1373  
Fragment?: false
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Genotype
Genotype
Symbol: Igf1r/Igf1r
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-IGF1R)7Jmcm/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Publication
25489988 | J:274567
 
First Author: Sapra G
Year: 2014
Journal: Nat Commun
Title: The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice.
Volume: 5
Pages: 5705
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Protein Coding Gene
MGI:96432 | Igf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14597618 | J:87944
First Author: McMullen JR
Year: 2004
Journal: J Biol Chem
Title: The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.
Volume: 279
Issue: 6
Pages: 4782-93
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Publication
16983087 | J:114548
First Author: Bisping E
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.
Volume: 103
Issue: 39
Pages: 14471-6
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Protein Coding Gene
MGI:1333863 | Pde3b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96434 | Igf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1932389 | Tlr9
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q61409
Organism: Mus musculus/domesticus
Length: 1100  
Fragment?: false
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Protein
P09535
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: false
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Protein
Q9EQU3
Organism: Mus musculus/domesticus
Length: 1032  
Fragment?: false
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Publication
30412601 | J:267769
First Author: Jones RA
Year: 2018
Journal: PLoS One
Title: Comparative mRNA and miRNA transcriptome analysis of a mouse model of IGFIR-driven lung cancer.
Volume: 13
Issue: 11
Pages: e0206948
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Genotype
Genotype
Symbol: Tg(Myh6-IGF1R)7Jmcm/? Tg(Myh6-Pik3ca)1Siz/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Myh6-IGF1R)7Jmcm/? Tg(Myh6-Pik3r1/PIK3CA)BSiz/?
Background: involves: FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(SFTPC-rtTA)5Jaw/? Tg(tetO-IGF1R)1Ramo/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Scgb1a1-rtTA)1Jaw/? Tg(tetO-IGF1R)1Ramo/?
Background: involves: 129 * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Protein
P05017
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
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Protein Coding Gene
MGI:99454 | Irs1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95525 | Fgfr4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2445019 | Pik3c3
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom