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Search results 701 to 800 out of 2041 for Ins2

0.017s
Type Details Score
Publication
First Author: Wei FY
Year: 2011
Journal: J Clin Invest
Title: Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice.
Volume: 121
Issue: 9
Pages: 3598-608
Publication
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
Publication
First Author: Pomplun D
Year: 2007
Journal: Horm Metab Res
Title: Alterations of pancreatic beta-cell mass and islet number due to Ins2-controlled expression of Cre recombinase: RIP-Cre revisited; part 2.
Volume: 39
Issue: 5
Pages: 336-40
Publication
First Author: Son JE
Year: 2021
Journal: Nat Metab
Title: Irx3 and Irx5 in Ins2-Cre(+) cells regulate hypothalamic postnatal neurogenesis and leptin response.
Volume: 3
Issue: 5
Pages: 701-713
Publication
First Author: Tsai MJ
Year: 2014
Journal: Endocrinology
Title: TCTP is essential for β-cell proliferation and mass expansion during development and β-cell adaptation in response to insulin resistance.
Volume: 155
Issue: 2
Pages: 392-404
Publication
First Author: Yang Y
Year: 2017
Journal: Endocrinology
Title: Differential Gene Dosage Effects of Diabetes-Associated Gene GLIS3 in Pancreatic β Cell Differentiation and Function.
Volume: 158
Issue: 1
Pages: 9-20
Publication
First Author: Wijesekara N
Year: 2010
Journal: Diabetologia
Title: Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.
Volume: 53
Issue: 8
Pages: 1656-68
Publication
First Author: Yang YP
Year: 2017
Journal: Development
Title: The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Volume: 144
Issue: 2
Pages: 248-257
Publication
First Author: Wang S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.
Volume: 106
Issue: 24
Pages: 9715-20
Publication
First Author: George NM
Year: 2015
Journal: Mol Endocrinol
Title: Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.
Volume: 29
Issue: 11
Pages: 1594-607
Publication
First Author: Kahraman S
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Volume: 307
Issue: 10
Pages: E906-18
Publication
First Author: Fitzpatrick GV
Year: 2002
Journal: Nat Genet
Title: Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1.
Volume: 32
Issue: 3
Pages: 426-31
Publication
First Author: Broche B
Year: 2018
Journal: Diabetes
Title: Mitochondrial Protein UCP2 Controls Pancreas Development.
Volume: 67
Issue: 1
Pages: 78-84
Publication
First Author: Mellitzer G
Year: 2004
Journal: Mol Endocrinol
Title: Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice.
Volume: 18
Issue: 11
Pages: 2765-76
Publication
First Author: Gao N
Year: 2010
Journal: Mol Endocrinol
Title: Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.
Volume: 24
Issue: 8
Pages: 1594-604
Publication
First Author: Jonckheere N
Year: 2008
Journal: Dev Biol
Title: Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation.
Volume: 318
Issue: 2
Pages: 224-35
Publication
First Author: Dubois CL
Year: 2011
Journal: PLoS One
Title: Sox9-haploinsufficiency causes glucose intolerance in mice.
Volume: 6
Issue: 8
Pages: e23131
Publication
First Author: Prévot PP
Year: 2013
Journal: Gastroenterology
Title: Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.
Volume: 145
Issue: 3
Pages: 668-78.e3
Publication
First Author: Azzarelli R
Year: 2017
Journal: Dev Cell
Title: Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.
Volume: 41
Issue: 3
Pages: 274-286.e5
Publication
First Author: Berger M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion.
Volume: 112
Issue: 9
Pages: 2888-93
Publication
First Author: Nakhai H
Year: 2008
Journal: Development
Title: Conditional inactivation of Myc impairs development of the exocrine pancreas.
Volume: 135
Issue: 19
Pages: 3191-6
Publication
First Author: Jacquemin P
Year: 2000
Journal: Mol Cell Biol
Title: Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3.
Volume: 20
Issue: 12
Pages: 4445-54
Publication
First Author: Lemaire LA
Year: 2015
Journal: Development
Title: Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.
Volume: 142
Issue: 5
Pages: 858-70
Publication
First Author: Vanhorenbeeck V
Year: 2007
Journal: Dev Biol
Title: Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation.
Volume: 305
Issue: 2
Pages: 685-94
Publication
First Author: Lee NK
Year: 2007
Journal: Cell
Title: Endocrine regulation of energy metabolism by the skeleton.
Volume: 130
Issue: 3
Pages: 456-69
Publication
First Author: Wei J
Year: 2014
Journal: Diabetes
Title: Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.
Volume: 63
Issue: 3
Pages: 1021-31
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Ghazarian L
Year: 2013
Journal: Diabetes
Title: Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.
Volume: 62
Issue: 11
Pages: 3785-96
Publication
First Author: Mohan JF
Year: 2013
Journal: J Exp Med
Title: Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes.
Volume: 210
Issue: 11
Pages: 2403-14
Publication
First Author: Fu X
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation.
Volume: 110
Issue: 44
Pages: 17892-7
Publication
First Author: Georgia S
Year: 2004
Journal: J Clin Invest
Title: Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.
Volume: 114
Issue: 7
Pages: 963-8
Publication
First Author: Thayer TC
Year: 2016
Journal: Diabetes
Title: Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.
Volume: 65
Issue: 11
Pages: 3429-3439
Publication
First Author: Pearson JA
Year: 2019
Journal: Diabetes
Title: Altered Gut Microbiota Activate and Expand Insulin B15-23-Reactive CD8+ T Cells.
Volume: 68
Issue: 5
Pages: 1002-1013
Publication
First Author: Pearson JA
Year: 2016
Journal: Diabetes
Title: Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8+ T Cells.
Volume: 65
Issue: 6
Pages: 1679-89
Publication
First Author: Offield MF
Year: 1996
Journal: Development
Title: PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.
Volume: 122
Issue: 3
Pages: 983-95
Publication
First Author: Boyer DF
Year: 2006
Journal: Dev Biol
Title: Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.
Volume: 298
Issue: 2
Pages: 616-31
Publication
First Author: Lammert E
Year: 2001
Journal: Science
Title: Induction of pancreatic differentiation by signals from blood vessels.
Volume: 294
Issue: 5542
Pages: 564-7
Publication
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
Publication  
First Author: Ramzy A
Year: 2022
Journal: Endocrinology
Title: Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression.
Volume: 163
Issue: 6
Publication
First Author: Botezelli JD
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Adipose depot-specific upregulation of Ucp1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice.
Volume: 319
Issue: 3
Pages: E529-E539
Publication
First Author: Neumann UH
Year: 2016
Journal: Mol Metab
Title: Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival.
Volume: 5
Issue: 8
Pages: 731-736
Publication
First Author: Mohan JF
Year: 2011
Journal: J Exp Med
Title: Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion.
Volume: 208
Issue: 12
Pages: 2375-83
Publication
First Author: Bettini M
Year: 2020
Journal: Diabetes
Title: A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.
Volume: 69
Issue: 3
Pages: 392-400
Publication
First Author: Ramzy A
Year: 2018
Journal: Endocrinology
Title: Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacementby Islet Transplantation.
Volume: 159
Issue: 1
Pages: 83-102
Publication
First Author: Dionne DA
Year: 2016
Journal: Endocrinology
Title: Caloric Restriction Paradoxically Increases Adiposity in Mice With Genetically Reduced Insulin.
Volume: 157
Issue: 7
Pages: 2724-34
Publication
First Author: Nakayama M
Year: 2005
Journal: J Autoimmun
Title: Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.
Volume: 25
Issue: 3
Pages: 193-8
Publication
First Author: Nakayama M
Year: 2005
Journal: Nature
Title: Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.
Volume: 435
Issue: 7039
Pages: 220-3
Publication  
First Author: Moriyama H
Year: 2007
Journal: Diabetes Res Clin Pract
Title: Insulin as a T cell antigen in type 1 diabetes supported by the evidence from the insulin knockout NOD mice.
Volume: 77 Suppl 1
Pages: S155-60
Publication
First Author: Neumann UH
Year: 2016
Journal: Endocrinology
Title: Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Volume: 157
Issue: 3
Pages: 1007-12
Publication
First Author: Schechter R
Year: 2005
Journal: Biochem Biophys Res Commun
Title: The effect of insulin deficiency on tau and neurofilament in the insulin knockout mouse.
Volume: 334
Issue: 4
Pages: 979-86
Publication  
First Author: Lee J
Year: 2020
Journal: JCI Insight
Title: Insulin synthesized in the paraventricular nucleus of the hypothalamus regulates pituitary growth hormone production.
Volume: 5
Issue: 16
Publication
First Author: Moriyama H
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse.
Volume: 100
Issue: 18
Pages: 10376-81
Publication
First Author: Bettini M
Year: 2014
Journal: J Immunol
Title: TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
Volume: 193
Issue: 2
Pages: 571-9
Publication
First Author: Wright J
Year: 2013
Journal: J Clin Invest
Title: Dominant protein interactions that influence the pathogenesis of conformational diseases.
Volume: 123
Issue: 7
Pages: 3124-34
Publication
First Author: Faideau B
Year: 2004
Journal: J Immunol
Title: Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice.
Volume: 172
Issue: 1
Pages: 25-33
Publication  
First Author: Dubois-Lafforgue D
Year: 2002
Journal: Diabetes
Title: Proinsulin 2 knockout NOD mice: a model for genetic variation of insulin gene expression in type 1 diabetes.
Volume: 51 Suppl 3
Pages: S489-93
Publication
First Author: Thébault-Baumont K
Year: 2003
Journal: J Clin Invest
Title: Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice.
Volume: 111
Issue: 6
Pages: 851-7
Publication
First Author: Alejandro EU
Year: 2011
Journal: FASEB J
Title: Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription.
Volume: 25
Issue: 11
Pages: 3884-95
Publication
First Author: Paul L
Year: 2016
Journal: Diabetes
Title: Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells.
Volume: 65
Issue: 3
Pages: 687-98
Publication
First Author: Collombat P
Year: 2005
Journal: Development
Title: The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.
Volume: 132
Issue: 13
Pages: 2969-80
Publication
First Author: Fazio EN
Year: 2005
Journal: J Endocrinol
Title: Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1.
Volume: 187
Issue: 3
Pages: 407-18
Publication
First Author: Wilson ME
Year: 2005
Journal: Diabetes
Title: The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.
Volume: 54
Issue: 12
Pages: 3402-9
Publication
First Author: Nivlet L
Year: 2016
Journal: J Mol Endocrinol
Title: Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas.
Volume: 56
Issue: 2
Pages: 77-90
Publication
First Author: Zhang W
Year: 2006
Journal: Cell Metab
Title: PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Volume: 4
Issue: 6
Pages: 491-7
Publication
First Author: Romer AI
Year: 2019
Journal: Diabetes
Title: Murine Perinatal β-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1.
Volume: 68
Issue: 12
Pages: 2259-2271
Publication
First Author: Shih HP
Year: 2012
Journal: Development
Title: A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Volume: 139
Issue: 14
Pages: 2488-99
Publication
First Author: Bethea M
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis.
Volume: 316
Issue: 3
Pages: E397-E409
Publication
First Author: Ho KH
Year: 2020
Journal: Diabetes
Title: Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation.
Volume: 69
Issue: 9
Pages: 1936-1947
Publication
First Author: Schaffer AE
Year: 2010
Journal: Dev Cell
Title: Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Volume: 18
Issue: 6
Pages: 1022-9
Publication
First Author: Nelson SB
Year: 2007
Journal: Development
Title: The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.
Volume: 134
Issue: 13
Pages: 2491-500
Publication
First Author: Chen H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Impaired pancreatic development in Hif2-alpha deficient mice.
Volume: 399
Issue: 3
Pages: 440-5
Publication
First Author: Plank JL
Year: 2011
Journal: Dev Biol
Title: Influence and timing of arrival of murine neural crest on pancreatic beta cell development and maturation.
Volume: 349
Issue: 2
Pages: 321-30
Publication
First Author: Rachdi L
Year: 2014
Journal: Diabetologia
Title: Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass.
Volume: 57
Issue: 5
Pages: 960-9
Publication
First Author: Smith R
Year: 2009
Journal: Hum Mol Genet
Title: Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion.
Volume: 18
Issue: 20
Pages: 3942-54
Publication  
First Author: Baumann D
Year: 2020
Journal: Development
Title: Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.
Volume: 147
Issue: 7
Publication
First Author: Trojanowski BM
Year: 2020
Journal: J Endocrinol
Title: Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.
Volume: 244
Issue: 2
Pages: 323-337
Publication
First Author: Liu J
Year: 2011
Journal: J Biol Chem
Title: Islet-1 regulates Arx transcription during pancreatic islet alpha-cell development.
Volume: 286
Issue: 17
Pages: 15352-60
Publication
First Author: Iglesias J
Year: 2012
Journal: J Clin Invest
Title: PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Volume: 122
Issue: 11
Pages: 4105-17
Publication
First Author: Du A
Year: 2009
Journal: Diabetes
Title: Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Volume: 58
Issue: 9
Pages: 2059-69
Publication
First Author: Lu J
Year: 2010
Journal: Gastroenterology
Title: Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.
Volume: 138
Issue: 5
Pages: 1954-65
Publication
First Author: Yang YP
Year: 2011
Journal: Genes Dev
Title: Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.
Volume: 25
Issue: 16
Pages: 1680-5
Publication
First Author: Bonnavion R
Year: 2015
Journal: Mol Cell Biol
Title: Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors.
Volume: 35
Issue: 19
Pages: 3274-83
Publication
First Author: Kodani N
Year: 2020
Journal: iScience
Title: FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression.
Volume: 23
Issue: 1
Pages: 100798
Publication
First Author: Moon JH
Year: 2020
Journal: Diabetes
Title: Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.
Volume: 69
Issue: 2
Pages: 205-214
Publication
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
Publication
First Author: Tsuchiya Y
Year: 2018
Journal: J Cell Biol
Title: IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells.
Volume: 217
Issue: 4
Pages: 1287-1301
Publication
First Author: van Arensbergen J
Year: 2013
Journal: Genes Dev
Title: Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells.
Volume: 27
Issue: 1
Pages: 52-63
Publication
First Author: Wakae-Takada N
Year: 2013
Journal: Diabetologia
Title: Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin.
Volume: 56
Issue: 4
Pages: 856-66
Publication
First Author: Li F
Year: 2015
Journal: Endocrinology
Title: Conditional deletion of Men1 in the pancreatic β-cell leads to glucagon-expressing tumor development.
Volume: 156
Issue: 1
Pages: 48-57
Publication
First Author: Kon N
Year: 2012
Journal: J Biol Chem
Title: Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice.
Volume: 287
Issue: 7
Pages: 5102-11
Publication  
First Author: Kim-Muller JY
Year: 2016
Journal: Nat Commun
Title: Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice.
Volume: 7
Pages: 12631
Publication
First Author: Abarinov V
Year: 2023
Journal: Genes Dev
Title: Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.
Volume: 37
Issue: 11-12
Pages: 490-504
Publication
First Author: Lu J
Year: 2012
Journal: Oncogene
Title: Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse.
Volume: 31
Issue: 31
Pages: 3647-54
Publication
First Author: Melzer MK
Year: 2023
Journal: BMC Biol
Title: TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.
Volume: 21
Issue: 1
Pages: 55
Publication
First Author: Padgett LR
Year: 2021
Journal: FASEB J
Title: Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development.
Volume: 35
Issue: 5
Pages: e21473
Publication  
First Author: Rupani DN
Year: 2023
Journal: Development
Title: Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling.
Volume: 150
Issue: 2
Publication  
First Author: Chen C
Year: 2019
Journal: Development
Title: Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.
Volume: 146
Issue: 13
Publication  
First Author: Mehanna S
Year: 2023
Journal: Dev Biol
Title: Beclin1 is essential for the pancreas development.
Volume: 504
Pages: 113-119
Publication
First Author: Rodríguez-Seguel E
Year: 2020
Journal: J Pathol
Title: Loss of GATA4 causes ectopic pancreas in the stomach.
Volume: 250
Issue: 4
Pages: 362-373
Publication
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33