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Search results 701 to 800 out of 1089 for Jak2

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Type Details Score
Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
17565041 | J:124086
First Author: Li Z
Year: 2007
Journal: Mol Endocrinol
Title: SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms.
Volume: 21
Issue: 9
Pages: 2270-81
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Publication
20562009 | J:163178
First Author: Helmer RA
Year: 2010
Journal: Mol Cell Endocrinol
Title: Prolactin-induced Jak2 phosphorylation of RUSH: a key element in Jak/RUSH signaling.
Volume: 325
Issue: 1-2
Pages: 143-9
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Publication
26175407 | J:222996
First Author: Silvennoinen O
Year: 2015
Journal: Cancer Cell
Title: Targeting the Inactive Conformation of JAK2 in Hematological Malignancies.
Volume: 28
Issue: 1
Pages: 1-2
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UniProt Feature
UniProt Feature
Begin: 152
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 152
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UniProt Feature
UniProt Feature
Begin: 1
Description: Tyrosine-protein kinase JAK2
Type: chain
End: 1132
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UniProt Feature
UniProt Feature
Begin: 737
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 737
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UniProt Feature
UniProt Feature
Begin: 195
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 195
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UniProt Feature
UniProt Feature
Begin: 1138
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 1138
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UniProt Feature
UniProt Feature
Begin: 985
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 985
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UniProt Feature
UniProt Feature
Begin: 285
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 285
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UniProt Feature
UniProt Feature
Begin: 153
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 153
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UniProt Feature
UniProt Feature
Begin: 201
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 201
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UniProt Feature
UniProt Feature
Begin: 453
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 453
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UniProt Feature
UniProt Feature
Begin: 425
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 425
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UniProt Feature
UniProt Feature
Begin: 467
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 467
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UniProt Feature
UniProt Feature
Begin: 455
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 455
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UniProt Feature
UniProt Feature
Begin: 488
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 488
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UniProt Feature
UniProt Feature
Begin: 484
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 484
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UniProt Feature
UniProt Feature
Begin: 503
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 503
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UniProt Feature
UniProt Feature
Begin: 367
Description: Phosphotyrosine; by JAK2
Type: modified residue
End: 367
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UniProt Feature
UniProt Feature
Begin: 494
Description: Phosphotyrosine; by JAK1, JAK2
Type: modified residue
End: 494
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Publication
8702638 | -
First Author: Nakamura N
Year: 1996
Journal: J Biol Chem
Title: An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells.
Volume: 271
Issue: 32
Pages: 19483-8
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Publication
10842184 | -
First Author: Stofega MR
Year: 2000
Journal: J Biol Chem
Title: Negative regulation of growth hormone receptor/JAK2 signaling by signal regulatory protein alpha.
Volume: 275
Issue: 36
Pages: 28222-9
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Publication
11779507 | -
First Author: Huang LJ
Year: 2001
Journal: Mol Cell
Title: The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor.
Volume: 8
Issue: 6
Pages: 1327-38
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Publication
32599005 | J:299783
First Author: Wadsworth PA
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Res
Title: JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation.
Volume: 1867
Issue: 10
Pages: 118786
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Publication
30944118 | J:276356
First Author: Jeong JJ
Year: 2019
Journal: Cancer Discov
Title: Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
Volume: 9
Issue: 6
Pages: 778-795
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Publication
28554737 | J:282295
First Author: Zhang H
Year: 2017
Journal: Kidney Int
Title: Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.
Volume: 92
Issue: 4
Pages: 909-921
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Publication
18160670 | J:134364
First Author: Tiedt R
Year: 2008
Journal: Blood
Title: Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.
Volume: 111
Issue: 8
Pages: 3931-40
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UniProt Feature
UniProt Feature
Begin: 201
Description: Phosphotyrosine; by TXK and JAK2
Type: modified residue
End: 201
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Publication
24268771 | J:205596
First Author: Waibel M
Year: 2013
Journal: Cell Rep
Title: Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.
Volume: 5
Issue: 4
Pages: 1047-59
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Publication
21531978 | J:174814
First Author: Shide K
Year: 2011
Journal: Blood
Title: R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm.
Volume: 117
Issue: 25
Pages: 6866-75
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Publication
21685897 | J:173530
First Author: Russell RC
Year: 2011
Journal: Nat Med
Title: Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
Volume: 17
Issue: 7
Pages: 845-53
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Publication
10502458 | J:156077
First Author: Hellgren G
Year: 1999
Journal: Growth Horm IGF Res
Title: The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver.
Volume: 9
Issue: 3
Pages: 212-8
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Publication
10733929 | J:61476
First Author: Kumano K
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Blockade of JAK2 by tyrphostin AG-490 inhibits antigen-induced eosinophil recruitment into the mouse airways.
Volume: 270
Issue: 1
Pages: 209-14
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Publication
26175414 | J:222994
First Author: Wu SC
Year: 2015
Journal: Cancer Cell
Title: Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.
Volume: 28
Issue: 1
Pages: 29-41
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Publication
24037089 | J:228994
First Author: Chan SR
Year: 2014
Journal: Cell Death Differ
Title: Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.
Volume: 21
Issue: 2
Pages: 234-46
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Publication
28068330 | J:243149
First Author: Tsuruta-Kishino T
Year: 2017
Journal: Oncogene
Title: Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.
Volume: 36
Issue: 23
Pages: 3300-3311
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Publication
30872773 | J:275894
First Author: Patera F
Year: 2019
Journal: Sci Rep
Title: Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis.
Volume: 9
Issue: 1
Pages: 4491
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Publication
25825724 | J:220454
First Author: Hammarén HM
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation.
Volume: 112
Issue: 15
Pages: 4642-7
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Publication
9473212 | -
First Author: Yamashita Y
Year: 1998
Journal: Blood
Title: Tec and Jak2 kinases cooperate to mediate cytokine-driven activation of c-fos transcription.
Volume: 91
Issue: 5
Pages: 1496-507
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Transgene
MGI:5444026 | Tg(H2-K<b>-Jak2*V617F)2Shmd
Type: transgene
Organism: mouse, laboratory
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UniProt Feature
UniProt Feature
Begin: 88
Description: Phosphotyrosine; by ABL, LYN, SRC and JAK2
Type: modified residue
End: 88
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UniProt Feature
UniProt Feature
Begin: 701
Description: Phosphotyrosine; by JAK1, JAK2 or TYK2
Type: modified residue
End: 701
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UniProt Feature
UniProt Feature
Begin: 518
Description: Phosphotyrosine; by autocatalysis, LYN and JAK2
Type: modified residue
End: 518
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UniProt Feature
UniProt Feature
Begin: 241
Description: Phosphotyrosine; by FGFR1, ABL1, FLT3 and JAK2
Type: modified residue
End: 241
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UniProt Feature
UniProt Feature
Begin: 439
Description: Phosphotyrosine; by JAK1, JAK2 and PDGFR
Type: modified residue
End: 439
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Publication
- | J:331302
First Author: Spivak JL, Williams DM, Zhao ZJ, Rogers O, Duffield AS, Hankins WD, Moliterno AR
Year: 2015
Journal: Blood
Title: MPL SV, a Unique MPN MPL Splice Variant, Provokes a Fulminant Myeloid Leukemia in a JAK2 V617F Transgenic Mouse Model of Polycythemia Vera
Volume: 126
Issue: 23
Pages: 484
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Publication
15475610 | -
First Author: Sandberg EM
Year: 2004
Journal: Cell Biochem Biophys
Title: Jak2 tyrosine kinase: a true jak of all trades?
Volume: 41
Issue: 2
Pages: 207-32
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Publication
17389152 | -
First Author: Hsu HC
Year: 2007
Journal: J Chin Med Assoc
Title: Pathogenetic role of JAK2 V617F mutation in chronic myeloproliferative disorders.
Volume: 70
Issue: 3
Pages: 89-93
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Publication
24354892 | J:210554
First Author: Varghese LN
Year: 2014
Journal: Biochem J
Title: Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.
Volume: 458
Issue: 2
Pages: 395-405
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Publication
21368206 | J:170821
First Author: Berry DC
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses.
Volume: 108
Issue: 11
Pages: 4340-5
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Publication
30463063 | J:328639
First Author: Swaminathan M
Year: 2019
Journal: Acta Haematol
Title: Unique Case of Myeloproliferative Neoplasm with Two Rare Clonal Abnormalities: Rare JAK2 Exon 12 Mutation and Rare e14a3 (b3a3) BCR/ABL Fusion Transcript.
Volume: 141
Issue: 1
Pages: 23-27
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Publication
21841788 | -
First Author: Ungureanu D
Year: 2011
Journal: Nat Struct Mol Biol
Title: The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.
Volume: 18
Issue: 9
Pages: 971-6
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Publication
17466371 | -
First Author: Karow A
Year: 2008
Journal: Leuk Res
Title: JAK2 mutations other than V617F: a novel mutation and mini review.
Volume: 32
Issue: 2
Pages: 365-6
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Publication
31709318 | J:285383
First Author: Sano S
Year: 2019
Journal: JACC Basic Transl Sci
Title: JAK2 V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure.
Volume: 4
Issue: 6
Pages: 684-697
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Publication
21457752 | -
First Author: Helmer RA
Year: 2011
Journal: Mol Cell Endocrinol
Title: Prolactin induces Jak2 phosphorylation of RUSHY195.
Volume: 338
Issue: 1-2
Pages: 79-83
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Interaction Experiment
Feener EP (2004)
Description: Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling.
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Interaction Experiment
Jaekel H (2011)
Description: Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control.
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Interaction Experiment
Yamauchi T (1997)
Description: Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone.
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Interaction Experiment
Huang HM (2005)
Description: Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells.
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Interaction Experiment
Fuhrer DK (1996)
Description: Complex formation of JAK2 with PP2A, P13K, and Yes in response to the hematopoietic cytokine interleukin-11.
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Interaction Experiment
Donaghy R (2019)
Description: The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination.
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Interaction Experiment
Rui L (2000)
Description: Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta.
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Publication
19290934 | -
First Author: Ghoreschi K
Year: 2009
Journal: Immunol Rev
Title: Janus kinases in immune cell signaling.
Volume: 228
Issue: 1
Pages: 273-87
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Publication
21533163 | -
First Author: Sanz A
Year: 2011
Journal: PLoS One
Title: Analysis of Jak2 catalytic function by peptide microarrays: the role of the JH2 domain and V617F mutation.
Volume: 6
Issue: 4
Pages: e18522
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Publication
9573010 | -
First Author: Chin H
Year: 1998
Journal: Blood
Title: Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.
Volume: 91
Issue: 10
Pages: 3734-45
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Publication
11923481 | -
First Author: Bahrenberg G
Year: 2002
Journal: Mol Endocrinol
Title: Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers.
Volume: 16
Issue: 4
Pages: 859-72
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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