|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 701 to 800 out of 849 for Mif

<< First    < Previous  |  Next >    Last >>
0.471s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
700556 | LOC700556
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
711990 | LOC711990
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Publication
12782713 | J:156237
First Author: Leng L
Year: 2003
Journal: J Exp Med
Title: MIF signal transduction initiated by binding to CD74.
Volume: 197
Issue: 11
Pages: 1467-76
•
•
•
•
•
Publication
24850900 | J:213506
First Author: Nagarajan P
Year: 2014
Journal: Mol Cancer Res
Title: MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma.
Volume: 12
Issue: 9
Pages: 1292-302
•
•
•
•
•
Pseudogene
MGI:1926282 | Smt3h1-ps
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI:2149598 | Smt3h2-ps4
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI:1926285 | Smt3h2-ps3
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI:1926284 | Smt3h2-ps2
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Publication
38703766 | J:355742
First Author: Alfahel L
Year: 2024
Journal: Cell Rep Med
Title: Targeting low levels of MIF expression as a potential therapeutic strategy for ALS.
Volume: 5
Issue: 5
Pages: 101546
•
•
•
•
•
Publication
26280537 | J:227353
First Author: Zheng Y
Year: 2015
Journal: Nat Cell Biol
Title: Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation.
Volume: 17
Issue: 10
Pages: 1348-55
•
•
•
•
•
Publication
35688953 | J:357612
First Author: Alaskarov A
Year: 2022
Journal: Sci Rep
Title: MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1.
Volume: 12
Issue: 1
Pages: 9570
•
•
•
•
•
Publication
35839070 | J:357314
First Author: Suresh V
Year: 2022
Journal: FASEB J
Title: MIF confers survival advantage to pancreatic CAFs by suppressing interferon pathway-induced p53-dependent apoptosis.
Volume: 36
Issue: 8
Pages: e22449
•
•
•
•
•
Publication
23044992 | J:233257
First Author: Mun SH
Year: 2013
Journal: J Bone Miner Res
Title: Deletion of CD74, a putative MIF receptor, in mice enhances osteoclastogenesis and decreases bone mass.
Volume: 28
Issue: 4
Pages: 948-59
•
•
•
•
•
Publication
24384723 | J:316980
 
First Author: Schulz R
Year: 2014
Journal: Cell Death Dis
Title: HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer.
Volume: 5
Pages: e980
•
•
•
•
•
Pseudogene
MGI:1859622 | Smt3h2-ps
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Publication
29095944 | J:252346
First Author: Korf H
Year: 2017
Journal: PLoS One
Title: MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset.
Volume: 12
Issue: 11
Pages: e0187455
•
•
•
•
•
Allele
Smt3h2-ps2<+> | MGI:3656607
 
Name: SMT3 suppressor of mif two 3 homolog 2, pseudogene 2 (S. cerevisiae); wild type
Allele Type: Not Specified
•
•
•
•
•
Allele
Smt3h2-ps<+> | MGI:3658317
 
Name: SMT3 suppressor of mif two 3 homolog 2, pseudogene (S. cerevisiae); wild type
Allele Type: Not Specified
•
•
•
•
•
Protein
P34884
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: false
•
•
•
•
•
Publication
31262807 | J:278205
First Author: Leyton-Jaimes MF
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: AAV2/9-mediated overexpression of MIF inhibits SOD1 misfolding, delays disease onset, and extends survival in mouse models of ALS.
Volume: 116
Issue: 29
Pages: 14755-14760
•
•
•
•
•
GO Term
GO:0035691 | macrophage migration inhibitory factor signaling pathway
•
•
•
•
•
Publication
2805816 | J:10071
First Author: Nishioka Y
Year: 1989
Journal: Cytogenet Cell Genet
Title: Genome comparison in the genus Mus: a study with B1, MIF (mouse interspersed fragment), centromeric, and Y-chromosomal repetitive sequences.
Volume: 50
Issue: 4
Pages: 195-200
•
•
•
•
•
Allele
Mif<em1Smoc> | MGI:7291075
Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Mif<em3(MIF)Smoc> | MGI:7291076
Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor); endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
•
•
•
•
•
Publication
36142647 | J:346976
 
First Author: Seidel F
Year: 2022
Journal: Int J Mol Sci
Title: Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice.
Volume: 23
Issue: 18
•
•
•
•
•
GO Term
GO:2000446 | regulation of macrophage migration inhibitory factor signaling pathway
•
•
•
•
•
GO Term
GO:2000448 | positive regulation of macrophage migration inhibitory factor signaling pathway
•
•
•
•
•
GO Term
GO:2000447 | negative regulation of macrophage migration inhibitory factor signaling pathway
•
•
•
•
•
Strain
MGI:6429179 | C57BL/6JSmoc-Mif<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:6429180 | C57BL/6JSmoc-Mif<em3(MIF)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
HT Experiment
E-TABM-524 | Transcription profiling of white adipose tissue from Lldlr-/- and Lldlr-/-Mif-/- mice
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Protein Coding Gene
MGI:2158813 | Sumo2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_CAROLIEiJ_G0013004 | -
Type: pseudogene
Organism: Mus caroli
•
•
•
•
•
Pseudogene
MGP_129S1SvImJ_G0014013 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_129S1SvImJ_G0014280 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_129S1SvImJ_G0014940 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AJ_G0014033 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AJ_G0014295 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AJ_G0014930 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AKRJ_G0013967 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AKRJ_G0014219 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_AKRJ_G0014870 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_BALBcJ_G0014245 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_BALBcJ_G0014887 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C3HHeJ_G0013824 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C3HHeJ_G0014074 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C3HHeJ_G0014722 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI_C57BL6J_2149598 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI_C57BL6J_1926285 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI_C57BL6J_1926284 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI_C57BL6J_1859622 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGI_C57BL6J_1926282 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C57BL6NJ_G0014422 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C57BL6NJ_G0014698 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_C57BL6NJ_G0015372 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_CASTEiJ_G0014331 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_CBAJ_G0013805 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_CBAJ_G0014059 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_CBAJ_G0014712 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_DBA2J_G0013882 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_DBA2J_G0014142 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_DBA2J_G0014792 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_FVBNJ_G0013883 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_FVBNJ_G0014139 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_FVBNJ_G0014776 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_LPJ_G0013962 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_LPJ_G0014233 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_LPJ_G0014893 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NODShiLtJ_G0013909 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NODShiLtJ_G0014176 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NODShiLtJ_G0014820 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NZOHlLtJ_G0014388 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NZOHlLtJ_G0014668 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_NZOHlLtJ_G0015357 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_PWKPhJ_G0014129 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_WSBEiJ_G0014413 | -
Type: pseudogene
Organism: mouse, laboratory
•
•
•
•
•
Pseudogene
MGP_SPRETEiJ_G0009974 | -
Type: pseudogene
Organism: Mus spretus
•
•
•
•
•
Publication
11138001 | J:66695
First Author: Brunkow ME
Year: 2001
Journal: Nat Genet
Title: Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
Volume: 27
Issue: 1
Pages: 68-73
•
•
•
•
•
Allele
Tg(tetO-Mif)279Aren | MGI:5461057
Name: transgene insertion 279, Douglas Arenberg
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:5461058 | B6.Cg-Tg(tetO-Mif)279Aren/J
Attribute String: mutant strain, transgenic
•
•
•
•
•
HT Experiment
E-MTAB-9392 | Role of Macrophage migration inhibitory factor (MIF) in pancreatic stellate cells (PSCs)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
10079069 | -
First Author: Sugimoto H
Year: 1999
Journal: Biochemistry
Title: Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution.
Volume: 38
Issue: 11
Pages: 3268-79
•
•
•
•
•
Publication
16331703 | -
First Author: Van Molle W
Year: 2005
Journal: Eur J Immunol
Title: How glucocorticoids control their own strength and the balance between pro- and anti-inflammatory mediators.
Volume: 35
Issue: 12
Pages: 3396-9
•
•
•
•
•
Publication
10644007 | -
First Author: Matsunaga J
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Macrophage migration inhibitory factor (MIF)--its role in catecholamine metabolism.
Volume: 45
Issue: 7
Pages: 1035-40
•
•
•
•
•
Protein Domain
IPR019829 | Macrophage_inhib_fac_CS
Type: Conserved_site
Description: Macrophage migration inhibitory factor (MIF) is a key regulatory cytokine within innate and adaptive immune responses, capable of promoting and modulating the magnitude of the response []. MIF is released from T-cells and macrophages, and acts within the neuroendocrine system. MIF is capable of tautomerase activity, although its biological function has not been fully characterised. It is induced by glucocorticoid and is capable of overriding the anti-inflammatory actions of glucocorticoid []. MIF regulates cytokine secretion and the expression of receptors involved in the immune response. It can be taken up into target cells in order to interact with intracellular signalling molecules, inhibiting p53 function, and/or activating components of the mitogen-activated protein kinase and Jun-activation domain-binding protein-1 (Jab-1) []. MIF has been linked to various inflammatory diseases, such as rheumatoid arthritis and atherosclerosis [].The MIF homologue D-dopachrome tautomerase () is involved in detoxification through the conversion of dopaminechrome (and possibly norepinephrinechrome), the toxic quinine product of the neurotransmitter dopamine (and norepinephrine), to an indole derivative that can serve as a precursor to neuromelanin [, ].The signature pattern for this entry is formed from a conserved region located in the central section.
•
•
•
•
•
Protein Domain
IPR001398 | Macrophage_inhib_fac
Type: Family
Description: Macrophage migration inhibitory factor (MIF) is a key regulatory cytokine within innate and adaptive immune responses, capable of promoting and modulating the magnitude of the response []. MIF is released from T-cells and macrophages, and acts within the neuroendocrine system. MIF is capable of tautomerase activity, although its biological function has not been fully characterised. It is induced by glucocorticoid and is capable of overriding the anti-inflammatory actions of glucocorticoid []. MIF regulates cytokine secretion and the expression of receptors involved in the immune response. It can be taken up into target cells in order to interact with intracellular signalling molecules, inhibiting p53 function, and/or activating components of the mitogen-activated protein kinase and Jun-activation domain-binding protein-1 (Jab-1) []. MIF has been linked to various inflammatory diseases, such as rheumatoid arthritis and atherosclerosis [].The MIF homologue D-dopachrome tautomerase () is involved in detoxification through the conversion of dopaminechrome (and possibly norepinephrinechrome), the toxic quinine product of the neurotransmitter dopamine (and norepinephrine), to an indole derivative that can serve as a precursor to neuromelanin [, ].
•
•
•
•
•
Protein Coding Gene
MGI:1336201 | Sumo3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
10857745 | J:62168
First Author: Means GD
Year: 2000
Journal: Genomics
Title: A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.
Volume: 65
Issue: 3
Pages: 213-23
•
•
•
•
•
Protein
O35215
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
•
•
•
•
•
Protein
Q545F0
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: false
•
•
•
•
•
Protein
G3UZN1
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: false
•
•
•
•
•
Protein
Q3UNI8
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
•
•
•
•
•
Publication
15225126 | -
First Author: Donn RP
Year: 2004
Journal: J Endocrinol
Title: Macrophage migration inhibitory factor: molecular, cellular and genetic aspects of a key neuroendocrine molecule.
Volume: 182
Issue: 1
Pages: 1-9
•
•
•
•
•
Publication
16628200 | -
First Author: Morand EF
Year: 2006
Journal: Nat Rev Drug Discov
Title: MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis.
Volume: 5
Issue: 5
Pages: 399-410
•
•
•
•
•
Publication
20624928 | -
First Author: Gimm T
Year: 2010
Journal: FASEB J
Title: Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1.
Volume: 24
Issue: 11
Pages: 4443-58
•
•
•
•
•
Protein
Q9JLS0
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
•
•
•
•
•
Publication
15930302 | -
First Author: Togashi A
Year: 2005
Journal: Cancer Res
Title: Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy.
Volume: 65
Issue: 11
Pages: 4817-26
•
•
•
•
•
Publication
21614900 | -
First Author: Nishimura S
Year: 2011
Journal: Eur J Gynaecol Oncol
Title: Expression of hypoxia-inducible 2 (HIG2) protein in uterine cancer.
Volume: 32
Issue: 2
Pages: 146-9
•
•
•
•
•
Protein Domain
IPR026190 | Hipoxia_HILPDA
Type: Family
Description: Hypoxia-inducible lipid droplet-associated protein (HILPDA), also known as hypoxia-inducible protein 2 (HIG2), increases intracellular lipid accumulation. It stimulates expression of cytokines including IL6, MIF and VEGFA. It also enhances cell growth and proliferation [, ]. Human HILPDA is highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. It is detected in some cervical and endometrial cancers [, , ].
•
•
•
•
•
Publication
9891849 | J:52460
First Author: Chen A
Year: 1998
Journal: Biochem Mol Biol Int
Title: Characterization of mouse ubiquitin-like SMT3A and SMT3B cDNAs and gene/pseudogenes.
Volume: 46
Issue: 6
Pages: 1161-74
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom