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Search results 701 to 800 out of 1328 for Myh6

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Type Details Score
Allele
Name: transgene insertion, Junichi Sadoshima
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Ajay M Shah
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Xiaoxiang Yan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Kristen Jepsen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: transgene insertion 3, Junichi Sadoshima
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 13, Junichi Sadoshima
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, coisogenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion 137, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: congenic, mutant strain, transgenic
Publication  
First Author: Murray TV
Year: 2015
Journal: J Mol Cell Cardiol
Title: Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription.
Volume: 79
Pages: 54-68
Allele
Name: transgene insertion 17.7, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion, Jeffrey Towbin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Jeffrey Towbin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 105, Haruaki Nakaya
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 111, Haruaki Nakaya
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: intergenic site 2; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: transgene insertion 1, Zhenwei Pan
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Tg(Myh6-Nox4)13Jusa/?
Background: FVB-Tg(Myh6-Nox4)13Jusa
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Nox4)3Jusa/?
Background: FVB-Tg(Myh6-Nox4)3Jusa
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Nox4)#Jusa/?
Background: FVB-Tg(Myh6-Nox4)#Jusa
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Nox4)1Ams/?
Background: B6.Cg-Tg(Myh6-Nox4)1Ams
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Dyrk1b)#Yax/?
Background: involves: C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Carroll KJ
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9.
Volume: 113
Issue: 2
Pages: 338-43
Allele
Name: transgene insertion 1, Stuart Orkin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Xiang-Dong Fu
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 15, Paul N Epstein
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 4, Nigel Mackman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: microRNA 208a; targeted mutation 1, Da-Zhi Wang
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: transgene insertion 3.11, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: transgene insertion 4.9, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Endonuclease, Reporter
Allele
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Endonuclease, Reporter
Allele
Name: transgene insertion G#2, Vincent M Christoffels
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 1, Masafumi Yano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Tg(Myh6-Myh7)137Rbns/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Strain
Attribute String: transgenic, mutant strain, congenic
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 3, Jonathan Epstein
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Kang YJ
Year: 1997
Journal: J Clin Invest
Title: Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity.
Volume: 100
Issue: 6
Pages: 1501-6
Publication
First Author: Yin X
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: Metallothionein as a compensatory component prevents intermittent hypoxia-induced cardiomyopathy in mice.
Volume: 277
Issue: 1
Pages: 58-66
Publication
First Author: Wang Y
Year: 2009
Journal: Diabetes
Title: Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling.
Volume: 58
Issue: 6
Pages: 1391-402
Publication
First Author: Cong W
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374).
Volume: 304
Issue: 8
Pages: E826-35
Publication
First Author: Yang X
Year: 2006
Journal: FASEB J
Title: Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress.
Volume: 20
Issue: 7
Pages: 1024-6
Publication
First Author: Dong F
Year: 2007
Journal: Diabetes
Title: Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.
Volume: 56
Issue: 9
Pages: 2201-12
Publication
First Author: Guo R
Year: 2009
Journal: J Mol Cell Cardiol
Title: Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction.
Volume: 47
Issue: 2
Pages: 228-37
Publication
First Author: Cai L
Year: 2005
Journal: Diabetes
Title: Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy.
Volume: 54
Issue: 6
Pages: 1829-37
Allele
Name: transgene insertion 1, Gerald W Dorn II
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Publication
First Author: Shankar TS
Year: 2021
Journal: Nat Commun
Title: Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis.
Volume: 12
Issue: 1
Pages: 4583
Publication
First Author: Zankov DP
Year: 2017
Journal: Circ J
Title: Differential Effects of Myocardial Afadin on Pressure Overload-Induced Compensated Cardiac Hypertrophy.
Volume: 81
Issue: 12
Pages: 1862-1870
Allele
Name: transgene insertion 18, Nigel Mackman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Ali J Marian
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Ali J Marian
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 22.3, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Knockdown
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Tomomi Ueyama
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: transgene insertion 1, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 326, Jeffrey Stock
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
Allele
Name: transgene insertion WT, Bao-Liang Song
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Martherus R
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Accelerated cardiac remodeling in desmoplakin transgenic mice in response to endurance exercise is associated with perturbed Wnt/β-catenin signaling.
Volume: 310
Issue: 2
Pages: H174-87
Publication
First Author: Albrecht LV
Year: 2015
Journal: J Cell Biol
Title: GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics.
Volume: 208
Issue: 5
Pages: 597-612
Allele
Name: transgene insertion, Eric N Olson
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Publication
First Author: Zhuang L
Year: 2022
Journal: Circulation
Title: DYRK1B-STAT3 Drives Cardiac Hypertrophy and Heart Failure by Impairing Mitochondrial Bioenergetics.
Volume: 145
Issue: 11
Pages: 829-846
Genotype
Symbol: Tg(Myh6-MT2A)15Pne/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-GAL4)G#2Vmc/?
Background: FVB-Tg(Myh6-GAL4)G#2Vmc
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Cand1)1Zpan/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Ogata T
Year: 2008
Journal: Mol Cell Biol
Title: MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance.
Volume: 28
Issue: 10
Pages: 3424-36
Publication
First Author: Luongo TS
Year: 2015
Journal: Cell Rep
Title: The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
Volume: 12
Issue: 1
Pages: 23-34
Publication
First Author: Naito D
Year: 2015
Journal: Am J Physiol Heart Circ Physiol
Title: The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes.
Volume: 309
Issue: 12
Pages: H2127-36
Publication
First Author: Hofmann T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Subunit composition of mammalian transient receptor potential channels in living cells.
Volume: 99
Issue: 11
Pages: 7461-6
Publication
First Author: Nomura S
Year: 2018
Journal: Nat Commun
Title: Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure.
Volume: 9
Issue: 1
Pages: 4435
Publication  
First Author: Li X
Year: 2022
Journal: Pharmacol Res
Title: Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Volume: 182
Pages: 106284
Allele
Name: transgene insertion 6, Section of Myocardial Biology - Fishman Lab
Allele Type: Transgenic
Attribute String: Transactivator
Publication
First Author: Cui M
Year: 2023
Journal: Dev Cell
Title: Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development.
Volume: 58
Issue: 24
Pages: 2867-2880.e7
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion 37, Eric N Olson
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
Allele
Name: transgene insertion, Eric N Olson
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
Publication
First Author: Sidell N
Year: 2007
Journal: Cancer Lett
Title: Inhibition of estrogen-induced mammary tumor formation in MMTV-aromatase transgenic mice by 4-chlorophenylacetate.
Volume: 251
Issue: 2
Pages: 302-10
Publication
First Author: Drosatos K
Year: 2016
Journal: Circ Res
Title: Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function.
Volume: 118
Issue: 2
Pages: 241-53
Publication  
First Author: Han Y
Year: 2022
Journal: Front Cardiovasc Med
Title: Loss of m6A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression.
Volume: 9
Pages: 852775
Publication
First Author: Pol CJ
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21.
Volume: 1865
Issue: 9
Pages: 2125-2137
Publication  
First Author: Wang X
Year: 2021
Journal: J Mol Cell Cardiol
Title: Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction.
Volume: 163
Pages: 9-19
Publication
First Author: Xiong D
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance.
Volume: 306
Issue: 3
Pages: H326-38
Allele
Name: transgene insertion 1, Kristen Jepsen
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
Allele
Name: transgene insertion 1, Fehaan Ahmad
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion HE, Daniel P Kelly
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Lim DS
Year: 2001
Journal: Circulation
Title: Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy.
Volume: 103
Issue: 6
Pages: 789-91
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Wullschleger M
Year: 2017
Journal: Cardiovasc Res
Title: Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.
Volume: 113
Issue: 5
Pages: 542-552
Strain
Attribute String: transgenic, mutant strain, coisogenic