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Search results 701 to 800 out of 5729 for Nlrp3

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Type Details Score
Publication
28784846 | J:251265
First Author: Lima-Junior DS
Year: 2017
Journal: J Immunol
Title: Dectin-1 Activation during Leishmania amazonensis Phagocytosis Prompts Syk-Dependent Reactive Oxygen Species Production To Trigger Inflammasome Assembly and Restriction of Parasite Replication.
Volume: 199
Issue: 6
Pages: 2055-2068
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Publication
26582949 | J:240017
First Author: Skeldon AM
Year: 2016
Journal: J Immunol
Title: Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.
Volume: 196
Issue: 1
Pages: 437-47
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Publication
29863495 | J:265439
First Author: Lau A
Year: 2018
Journal: J Clin Invest
Title: Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.
Volume: 128
Issue: 7
Pages: 2894-2913
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Publication
21037094 | J:166140
First Author: McCoy AJ
Year: 2010
Journal: J Immunol
Title: Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.
Volume: 185
Issue: 11
Pages: 7077-84
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Publication
21041719 | J:177970
First Author: Chuang YT
Year: 2011
Journal: Blood
Title: Tumor suppressor death-associated protein kinase is required for full IL-1β production.
Volume: 117
Issue: 3
Pages: 960-70
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Publication
22777876 | J:188004
First Author: Mori A
Year: 2012
Journal: Eur J Immunol
Title: The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.
Volume: 42
Issue: 10
Pages: 2709-19
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Publication
21228274 | J:188894
First Author: Harris J
Year: 2011
Journal: J Biol Chem
Title: Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Volume: 286
Issue: 11
Pages: 9587-97
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Publication
26214524 | J:225800
First Author: Koch KN
Year: 2015
Journal: J Clin Invest
Title: Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma.
Volume: 125
Issue: 8
Pages: 3297-302
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Publication
28576980 | J:251502
First Author: Li Y
Year: 2017
Journal: J Immunol
Title: TLR9 Regulates the NF-κB-NLRP3-IL-1β Pathway Negatively in Salmonella-Induced NKG2D-Mediated Intestinal Inflammation.
Volume: 199
Issue: 2
Pages: 761-773
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Publication
32321638 | J:297990
First Author: Liang S
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Inhibition of RIPK1/RIPK3 ameliorates osteoclastogenesis through regulating NLRP3-dependent NF-κB and MAPKs signaling pathways.
Volume: 526
Issue: 4
Pages: 1028-1035
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Publication
27607578 | J:315464
First Author: Yang J
Year: 2016
Journal: Cell Death Dis
Title: Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS.
Volume: 7
Issue: 9
Pages: e2363
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Publication
26320999 | J:243015
First Author: Aachoui Y
Year: 2015
Journal: Cell Host Microbe
Title: Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.
Volume: 18
Issue: 3
Pages: 320-32
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Publication
21349431 | J:168972
First Author: Guarda G
Year: 2011
Journal: Immunity
Title: Type I interferon inhibits interleukin-1 production and inflammasome activation.
Volume: 34
Issue: 2
Pages: 213-23
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Publication
30919410 | J:277770
First Author: Campos PC
Year: 2019
Journal: Eur J Immunol
Title: Brucella abortus nitric oxide metabolite regulates inflammasome activation and IL-1β secretion in murine macrophages.
Volume: 49
Issue: 7
Pages: 1023-1037
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Publication
19576795 | J:151628
First Author: Di Paolo NC
Year: 2009
Journal: Immunity
Title: Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo.
Volume: 31
Issue: 1
Pages: 110-21
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Publication
25225402 | J:216478
First Author: Dutra FF
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Hemolysis-induced lethality involves inflammasome activation by heme.
Volume: 111
Issue: 39
Pages: E4110-8
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Publication
32421904 | J:304482
First Author: Greaney AJ
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event.
Volume: 108
Issue: 3
Pages: 773-786
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Publication
23468973 | J:199501
First Author: Ea HK
Year: 2013
Journal: PLoS One
Title: Pathogenic role of basic calcium phosphate crystals in destructive arthropathies.
Volume: 8
Issue: 2
Pages: e57352
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Publication
23209411 | J:195453
First Author: Ramos HJ
Year: 2012
Journal: PLoS Pathog
Title: IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection.
Volume: 8
Issue: 11
Pages: e1003039
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Publication
25684123 | J:247187
First Author: Gentile LF
Year: 2015
Journal: Immunology
Title: Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation.
Volume: 145
Issue: 2
Pages: 300-11
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Publication
24082072 | J:202455
First Author: Maher BM
Year: 2013
Journal: Infect Immun
Title: Nlrp-3-driven interleukin 17 production by γδT cells controls infection outcomes during Staphylococcus aureus surgical site infection.
Volume: 81
Issue: 12
Pages: 4478-89
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Publication
31029578 | J:275922
 
First Author: Alarcon MML
Year: 2019
Journal: J Mol Cell Cardiol
Title: Cardiac arrhythmias after renal I/R depend on IL-1β.
Volume: 131
Pages: 101-111
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Publication
35714308 | J:336985
First Author: Agrawal M
Year: 2022
Journal: Blood
Title: TET2-mutant clonal hematopoiesis and risk of gout.
Volume: 140
Issue: 10
Pages: 1094-1103
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Publication
32003282 | J:309303
First Author: Cheng J
Year: 2020
Journal: Autophagy
Title: Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice.
Volume: 16
Issue: 12
Pages: 2193-2205
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Publication
21484785 | J:177309
First Author: Freigang S
Year: 2011
Journal: Eur J Immunol
Title: Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis.
Volume: 41
Issue: 7
Pages: 2040-51
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Publication
30748031 | J:276897
First Author: Lacey CA
Year: 2019
Journal: J Leukoc Biol
Title: IFN-γ-dependent nitric oxide suppresses Brucella-induced arthritis by inhibition of inflammasome activation.
Volume: 106
Issue: 1
Pages: 27-34
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Publication
21282379 | J:176847
First Author: Bulua AC
Year: 2011
Journal: J Exp Med
Title: Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS).
Volume: 208
Issue: 3
Pages: 519-33
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Publication
26536497 | J:252289
First Author: Oleszycka E
Year: 2016
Journal: FEBS J
Title: IL-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination.
Volume: 283
Issue: 1
Pages: 9-24
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Publication
29146733 | J:270169
First Author: Marneros AG
Year: 2018
Journal: FASEB J
Title: Effects of chronically increased VEGF-A on the aging heart.
Volume: 32
Issue: 3
Pages: 1550-1565
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Publication
33621212 | J:337985
 
First Author: Kurihara C
Year: 2021
Journal: JCI Insight
Title: Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment.
Volume: 6
Issue: 6
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Publication
22046355 | J:178074
First Author: Lichtnekert J
Year: 2011
Journal: PLoS One
Title: Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.
Volume: 6
Issue: 10
Pages: e26778
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Publication
25815426 | J:222974
First Author: Lee DJ
Year: 2015
Journal: J Invest Dermatol
Title: Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment.
Volume: 135
Issue: 8
Pages: 2012-2020
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Publication
29352265 | J:305141
First Author: Li Y
Year: 2018
Journal: Cell Death Differ
Title: Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection.
Volume: 25
Issue: 7
Pages: 1304-1318
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Publication
20566831 | J:162019
First Author: Tsuchiya K
Year: 2010
Journal: J Immunol
Title: Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.
Volume: 185
Issue: 2
Pages: 1186-95
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Publication
23221343 | J:194155
First Author: Mulay SR
Year: 2013
Journal: J Clin Invest
Title: Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion.
Volume: 123
Issue: 1
Pages: 236-46
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Publication
19139171 | J:144019
First Author: Ichinohe T
Year: 2009
Journal: J Exp Med
Title: Inflammasome recognition of influenza virus is essential for adaptive immune responses.
Volume: 206
Issue: 1
Pages: 79-87
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Publication
27869651 | J:239745
First Author: Leaf IA
Year: 2017
Journal: J Clin Invest
Title: Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury.
Volume: 127
Issue: 1
Pages: 321-334
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Publication
38352874 | J:350738
 
First Author: Srinivasan S
Year: 2024
Journal: Front Immunol
Title: Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.
Volume: 15
Pages: 1323409
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Publication
22213227 | J:187789
First Author: Mankan AK
Year: 2012
Journal: Eur J Immunol
Title: The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.
Volume: 42
Issue: 3
Pages: 710-5
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Publication
21471445 | J:173098
First Author: Lalor SJ
Year: 2011
Journal: J Immunol
Title: Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.
Volume: 186
Issue: 10
Pages: 5738-48
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Publication
28786745 | J:324321
First Author: Spalinger MR
Year: 2017
Journal: Autophagy
Title: PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner.
Volume: 13
Issue: 9
Pages: 1590-1601
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Publication
24453977 | J:246598
First Author: Ataide MA
Year: 2014
Journal: PLoS Pathog
Title: Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Volume: 10
Issue: 1
Pages: e1003885
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Publication
26978520 | J:274957
First Author: Ciraci C
Year: 2016
Journal: PLoS One
Title: Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.
Volume: 11
Issue: 3
Pages: e0151252
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Publication
22911706 | J:189888
First Author: Abdalla H
Year: 2012
Journal: PLoS One
Title: Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.
Volume: 7
Issue: 7
Pages: e40722
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Publication
23307811 | J:211694
First Author: Case CL
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila.
Volume: 110
Issue: 5
Pages: 1851-6
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Publication
28087651 | J:243148
First Author: Orlowski GM
Year: 2017
Journal: J Leukoc Biol
Title: Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
Volume: 102
Issue: 1
Pages: 7-17
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Publication
23509366 | J:195291
First Author: Uchiyama R
Year: 2013
Journal: J Immunol
Title: Fas-mediated inflammatory response in Listeria monocytogenes infection.
Volume: 190
Issue: 8
Pages: 4245-54
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Publication
36537208 | J:360032
First Author: Yalcinkaya M
Year: 2023
Journal: Cardiovasc Res
Title: Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion.
Volume: 119
Issue: 4
Pages: 969-981
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Publication
23460746 | J:194921
First Author: Gomes MT
Year: 2013
Journal: J Immunol
Title: Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.
Volume: 190
Issue: 7
Pages: 3629-38
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Publication
21533069 | J:294782
First Author: Zheng Y
Year: 2011
Journal: PLoS Pathog
Title: A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.
Volume: 7
Issue: 4
Pages: e1002026
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Publication
32070376 | J:299804
First Author: Zhao Z
Year: 2020
Journal: J Neuroinflammation
Title: A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration.
Volume: 17
Issue: 1
Pages: 64
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Publication
24484406 | J:208779
First Author: Hanamsagar R
Year: 2014
Journal: J Neurochem
Title: Critical role for the AIM2 inflammasome during acute CNS bacterial infection.
Volume: 129
Issue: 4
Pages: 704-11
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Publication
26253422 | J:242786
 
First Author: Ydens E
Year: 2015
Journal: J Neuroinflammation
Title: Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes.
Volume: 12
Pages: 143
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Publication
28447181 | J:327379
First Author: Ye Y
Year: 2017
Journal: Cardiovasc Drugs Ther
Title: SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation of the Effects with Saxagliptin, a DPP4 Inhibitor.
Volume: 31
Issue: 2
Pages: 119-132
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Publication
29588315 | J:280022
First Author: Westerterp M
Year: 2018
Journal: Circulation
Title: Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis.
Volume: 138
Issue: 9
Pages: 898-912
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Publication
22241982 | J:183297
First Author: Ceballos-Olvera I
Year: 2011
Journal: PLoS Pathog
Title: Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious.
Volume: 7
Issue: 12
Pages: e1002452
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Publication
23075849 | J:189217
First Author: Huber S
Year: 2012
Journal: Nature
Title: IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.
Volume: 491
Issue: 7423
Pages: 259-63
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Publication
22634614 | J:188954
First Author: Eigenbrod T
Year: 2012
Journal: J Immunol
Title: Bacterial RNA mediates activation of caspase-1 and IL-1β release independently of TLRs 3, 7, 9 and TRIF but is dependent on UNC93B.
Volume: 189
Issue: 1
Pages: 328-36
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GO Term
GO:0072559 | NLRP3 inflammasome complex
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Publication
22002608 | J:193522
First Author: Kayagaki N
Year: 2011
Journal: Nature
Title: Non-canonical inflammasome activation targets caspase-11.
Volume: 479
Issue: 7371
Pages: 117-21
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Publication
22297845 | J:181354
First Author: Henao-Mejia J
Year: 2012
Journal: Nature
Title: Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Volume: 482
Issue: 7384
Pages: 179-85
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Publication
23630357 | J:204774
First Author: Shenderov K
Year: 2013
Journal: J Immunol
Title: Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.
Volume: 190
Issue: 11
Pages: 5722-30
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Publication
29515594 | J:327776
 
First Author: Rojas Márquez JD
Year: 2018
Journal: Front Immunol
Title: Mammalian Target of Rapamycin Inhibition in Trypanosoma cruzi-Infected Macrophages Leads to an Intracellular Profile That Is Detrimental for Infection.
Volume: 9
Pages: 313
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Publication
30937919 | J:346788
First Author: Schwartz C
Year: 2019
Journal: Allergy
Title: Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.
Volume: 74
Issue: 10
Pages: 1920-1933
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Publication
26529046 | J:231058
First Author: Mizutani T
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice.
Volume: 56
Issue: 12
Pages: 7122-9
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Publication
17442855 | J:123498
First Author: Lamkanfi M
Year: 2007
Journal: J Leukoc Biol
Title: Caspase-1 inflammasomes in infection and inflammation.
Volume: 82
Issue: 2
Pages: 220-5
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Protein Coding Gene
MGP_CAROLIEiJ_G0016439 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018154 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2653833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017569 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017274 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
37256935 | J:336372
First Author: Colantuoni M
Year: 2023
Journal: Sci Transl Med
Title: Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders.
Volume: 15
Issue: 698
Pages: eade3856
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Publication
- | J:216048
     
First Author: Shi H
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Park4. Updated on December 2, 2014
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Publication
- | J:234254
     
First Author: Shi H
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Park7
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Publication
- | J:192651
     
First Author: Beutler B
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct Data Submission
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Publication
- | J:220071
     
First Author: Shi H
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Park6 (Updated on April 7, 2015)
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Publication
- | J:217294
     
First Author: Shi H
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Park5. Updated on January 23, 2015
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Publication
30742078 | J:282489
First Author: Erlich Z
Year: 2019
Journal: Nat Immunol
Title: Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model.
Volume: 20
Issue: 4
Pages: 397-406
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Publication
38838044 | J:349921
First Author: de Sá KSG
Year: 2024
Journal: PLoS Pathog
Title: Pulmonary inflammation and viral replication define distinct clinical outcomes in fatal cases of COVID-19.
Volume: 20
Issue: 6
Pages: e1012222
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Title: Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD.
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Title: A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.
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First Author: Shi H
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Park8
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First Author: Ding X
Year: 2019
Journal: J Am Heart Assoc
Title: Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 Deficiency in Vascular Smooth Muscle Cells Prevents Arteriovenous Fistula Failure Despite Chronic Kidney Disease.
Volume: 8
Issue: 1
Pages: e011211
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First Author: Dostert C
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Journal: Science
Title: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
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Title: Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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