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Search results 701 to 729 out of 729 for Nras

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Type Details Score
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Genotype
Symbol: Sox10/Sox10<+> Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Trp53/Trp53 Tg(Tyr-cre/ERT2)13Bos/? Tg(Tyr-NRAS*Q61K)1Bee/?
Background: FVB.Cg-Tg(Tyr-cre/ERT2)13Bos Trp53 Tg(Tyr-NRAS*Q61K)1Bee
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Zhou X
Year: 2019
Journal: J Proteome Res
Title: Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment.
Volume: 18
Issue: 4
Pages: 1542-1552
Publication  
First Author: Prescott K
Year: 2023
Journal: Front Mol Neurosci
Title: Blocking of microglia-astrocyte proinflammatory signaling is beneficial following stroke.
Volume: 16
Pages: 1305949
Publication
First Author: Mukhopadhyay P
Year: 2016
Journal: Oncogene
Title: Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes.
Volume: 35
Issue: 25
Pages: 3342-50
Publication
First Author: Zingg D
Year: 2017
Journal: Cell Rep
Title: The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.
Volume: 20
Issue: 4
Pages: 854-867
Publication
First Author: Bajenaru ML
Year: 2001
Journal: Glia
Title: Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes.
Volume: 33
Issue: 4
Pages: 314-23
Publication
First Author: Uka R
Year: 2020
Journal: Oncogene
Title: Temporal activation of WNT/β-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Volume: 39
Issue: 20
Pages: 4132-4154
Publication
First Author: Schaefer SM
Year: 2017
Journal: Oncogene
Title: Sox2 is dispensable for primary melanoma and metastasis formation.
Volume: 36
Issue: 31
Pages: 4516-4524
Publication  
First Author: Zingg D
Year: 2015
Journal: Nat Commun
Title: The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Volume: 6
Pages: 6051
Publication
First Author: Vandamme N
Year: 2020
Journal: Cancer Res
Title: The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype.
Volume: 80
Issue: 14
Pages: 2983-2995
Strain
Attribute String: transgenic, targeted mutation, mutant strain, congenic
Genotype
Symbol: Cdkn2a/Cdkn2a Nras/Nras Stk11/Stk11 Tg(Tyr-cre/ERT2)13Bos/?
Background: B6J.Cg-Tg(Tyr-cre/ERT2)13Bos Nras Cdkn2a Stk11
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication      
First Author: Lazar I
Year: 2022
Journal: J Invest Dermatol
Title: Adipocyte Extracellular Vesicles Decrease p16INK4A in Melanoma: An Additional Link between Obesity and Cancer.
Publication
First Author: Sohier P
Year: 2018
Journal: Pigment Cell Melanoma Res
Title: A histopathological classification system of Tyr::NRAS(Q61K) murine melanocytic lesions: A reproducible simplified classification.
Volume: 31
Issue: 3
Pages: 423-431
Publication
First Author: van der Weyden L
Year: 2016
Journal: J Pathol
Title: Cross-species models of human melanoma.
Volume: 238
Issue: 2
Pages: 152-65
Genotype
Symbol: Cdkn2a/Cdkn2a Ezh2/Ezh2<+> Nras/Nras<+> Tg(Tyr-cre/ERT2)13Bos/?
Background: involves: 129 * 129S4/SvJae * 129P2/OlaHsd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Olvedy M
Year: 2017
Journal: J Clin Invest
Title: Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma.
Volume: 127
Issue: 6
Pages: 2310-2325
Publication
First Author: Zingg D
Year: 2018
Journal: Cancer Cell
Title: EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Volume: 34
Issue: 1
Pages: 69-84.e14
Publication
First Author: Varum S
Year: 2019
Journal: Cell Stem Cell
Title: Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.
Volume: 24
Issue: 4
Pages: 637-653.e9
Publication
First Author: Karras P
Year: 2022
Journal: Nature
Title: A cellular hierarchy in melanoma uncouples growth and metastasis.
Volume: 610
Issue: 7930
Pages: 190-198
Publication  
First Author: Kirschner LS
Year: 2016
Journal: Mol Cell Endocrinol
Title: Mouse models of thyroid cancer: A 2015 update.
Volume: 421
Pages: 18-27
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112