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Search results 701 to 800 out of 1201 for Pax5

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Type Details Score
Genotype
Symbol: Atp11c/? Tg(IghelMD4)4Ccg/?
Background: involves: C57BL/6 * C57BL/6JApb
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh<+>
Background: involves: 129 * 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Pknox1/Pknox1 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Nechanitzky R
Year: 2013
Journal: Nat Immunol
Title: Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.
Volume: 14
Issue: 8
Pages: 867-75
Publication
First Author: Rehg JE
Year: 2008
Journal: Comp Med
Title: Utility of antiPax5 in the diagnosis of lymphoproliferative disorders and neoplasia in mice.
Volume: 58
Issue: 3
Pages: 246-52
Publication
First Author: Savitsky D
Year: 2006
Journal: J Exp Med
Title: B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion.
Volume: 203
Issue: 10
Pages: 2305-14
Publication
First Author: Sitnicka E
Year: 2003
Journal: J Exp Med
Title: Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.
Volume: 198
Issue: 10
Pages: 1495-506
Publication
First Author: Malin S
Year: 2010
Journal: Nat Immunol
Title: Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.
Volume: 11
Issue: 2
Pages: 171-9
Publication
First Author: Gerasimova T
Year: 2015
Journal: Genes Dev
Title: A structural hierarchy mediated by multiple nuclear factors establishes IgH locus conformation.
Volume: 29
Issue: 16
Pages: 1683-95
Publication
First Author: Oguro H
Year: 2010
Journal: Cell Stem Cell
Title: Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.
Volume: 6
Issue: 3
Pages: 279-86
Publication
First Author: Dias S
Year: 2005
Journal: J Exp Med
Title: Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors.
Volume: 201
Issue: 6
Pages: 971-9
Publication
First Author: Pongubala JM
Year: 2008
Journal: Nat Immunol
Title: Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.
Volume: 9
Issue: 2
Pages: 203-15
Publication
First Author: O'Riordan M
Year: 1999
Journal: Immunity
Title: Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.
Volume: 11
Issue: 1
Pages: 21-31
Publication  
First Author: Jacoby E
Year: 2016
Journal: Nat Commun
Title: CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Volume: 7
Pages: 12320
Publication
First Author: Mansson R
Year: 2010
Journal: Blood
Title: Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.
Volume: 115
Issue: 13
Pages: 2601-9
Publication
First Author: Muto A
Year: 2010
Journal: EMBO J
Title: Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch.
Volume: 29
Issue: 23
Pages: 4048-61
Publication
First Author: Xue HH
Year: 2007
Journal: Immunity
Title: The transcription factor GABP is a critical regulator of B lymphocyte development.
Volume: 26
Issue: 4
Pages: 421-31
Publication
First Author: Kallies A
Year: 2007
Journal: Immunity
Title: Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.
Volume: 26
Issue: 5
Pages: 555-66
Publication
First Author: Zidi B
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling.
Volume: 116
Issue: 1
Pages: 211-216
Publication
First Author: O'Brien P
Year: 2011
Journal: Cancer Res
Title: The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease.
Volume: 71
Issue: 24
Pages: 7345-50
Publication
First Author: Knoll M
Year: 2013
Journal: Eur J Immunol
Title: miR-221 redirects precursor B cells to the BM and regulates their residence.
Volume: 43
Issue: 9
Pages: 2497-506
Publication
First Author: Fischer U
Year: 2015
Journal: Nat Genet
Title: Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Volume: 47
Issue: 9
Pages: 1020-1029
Publication
First Author: Almeida ARM
Year: 2021
Journal: Nat Commun
Title: Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Volume: 12
Issue: 1
Pages: 7268
Allele
Name: E26 avian leukemia oncogene 1, 5' domain; targeted mutation 1, Frederick W Alt
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: SWI/SNF related BAF chromatin remodeling complex subunit C1; targeted mutation 2.1, Rho H Seong
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: transcription factor 3; targeted mutation 1, Michael L Cleary
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
Allele
Name: Bruton agammaglobulinemia tyrosine kinase; targeted mutation 1, Wasif Kahn
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: transcription factor 3; targeted mutation 2, Cornelis Murre
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: C-C motif chemokine receptor 9; targeted mutation 1.1, Bernard Malissen
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: transcription factor 3; targeted mutation 2, Yuan Zhuang
Allele Type: Targeted
Allele
Name: transcription factor 12; targeted mutation 1, Yuan Zhuang
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: B cell linker; targeted mutation 1, Andrew C Chan
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: CD79B antigen; targeted mutation 2.1, Michel C Nussenzweig
Allele Type: Targeted
Attribute String: Null/knockout
Transgene
Type: transgene
Organism: mouse, laboratory
Allele
Name: CD79A antigen (immunoglobulin-associated alpha); targeted mutation 5.1, University of Cologne
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: feline sarcoma oncogene; targeted mutation 2, Peter A Greer
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: endoplasmic reticulum to nucleus signalling 1; targeted mutation 1, Randal J Kaufman
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: lymphoblastomic leukemia 1; targeted mutation 1, Fred Sablitzky
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: zinc finger and BTB domain containing 7a; targeted mutation 1, Pier Paolo Pandolfi
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: phospholipase C, gamma 2; targeted mutation 1.1, Tomohiro Kurosaki
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: C-X-C motif chemokine receptor 4; targeted mutation 3.1, Yong-Rui Zou
Allele Type: Targeted
Attribute String: Null/knockout
Regulatory Region
Type: enhancer
Organism: mouse, laboratory
Allele  
Name: immunoglobulin heavy constant mu; targeted mutation 1.1, Ahmed Khamlichi
Allele Type: Targeted
Transgene
Type: transgene
Organism: mouse, laboratory
Allele
Name: IKAROS family zinc finger 1; targeted mutation 3.1, Meinrad Busslinger
Allele Type: Targeted
Attribute String: Conditional ready
Allele
Name: marginal zone B and B1 cell-specific protein 1; targeted mutation 1.2, Rudolf Grosschedl
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: microRNA cluster 30, including Mir16-1 through Mir15a; endonuclease-mediated mutation 1, Xiao-yan Zhou
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele
Name: eukaryotic translation initiation factor 4A1; targeted mutation 1.1, Douglas Strathdee
Allele Type: Targeted
Attribute String: Conditional ready
Genotype
Symbol: Tcf12/Tcf12<+> Tcf4/Tcf4<+>
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Chek2/Chek2<+> Rad50/Rad50
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Rad50/Rad50 Smc1a/Smc1a
Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Srsf3/Srsf3 Cd79a/Cd79a<+>
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(IghelMD4)4Ccg/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Il2/Il2 Il4/Il4
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dicer1/Dicer1 Cd79a/Cd79a<+>
Background: involves: BALB/c
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Plcg2/Plcg2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Abl1/Abl1
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Abl1/Abl1
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Rr161/Rr161
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Mx1-cre)1Cgn/? Tnfrsf13c/Tnfrsf13c
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a<+> Cd79b/Cd79b
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b<+>
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Cd79b/Cd79b
Background: involves: 129P2/OlaHsd
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Ly6e-MALT1)#Isg/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Pax5/Pax5<+> Tcf3/Tcf3<+> Cd19/Cd19<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cd79a/Cd79a Mzb1/Mzb1
Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Allele
Name: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin); targeted mutation 1, Edward A Clark
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Ets1/Ets1
Background: B6.129S4-Ets1
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Saifudeen Z
Year: 2012
Journal: PLoS One
Title: A p53-Pax2 pathway in kidney development: implications for nephrogenesis.
Volume: 7
Issue: 9
Pages: e44869
Publication
First Author: Grote D
Year: 2006
Journal: Development
Title: Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.
Volume: 133
Issue: 1
Pages: 53-61
Publication  
First Author: Jiang XX
Year: 2015
Journal: Sci Rep
Title: Epigenetic Regulation of Antibody Responses by the Histone H2A Deubiquitinase MYSM1.
Volume: 5
Pages: 13755
Publication
First Author: Li CY
Year: 2007
Journal: Leukemia
Title: Overexpression of a hematopoietic transcriptional regulator EDAG induces myelopoiesis and suppresses lymphopoiesis in transgenic mice.
Volume: 21
Issue: 11
Pages: 2277-86
Publication
First Author: Wada H
Year: 2011
Journal: Int Immunol
Title: Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.
Volume: 23
Issue: 1
Pages: 65-74
Publication  
First Author: Kellner J
Year: 2019
Journal: JCI Insight
Title: Definition of a multiple myeloma progenitor population in mice driven by enforced expression of XBP1s.
Volume: 4
Issue: 7
Publication
First Author: Chen C
Year: 2022
Journal: Nat Commun
Title: Cancer co-opts differentiation of B-cell precursors into macrophage-like cells.
Volume: 13
Issue: 1
Pages: 5376
Publication
First Author: von Muenchow L
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Permissive roles of cytokines interleukin-7 and Flt3 ligand in mouse B-cell lineage commitment.
Volume: 113
Issue: 50
Pages: E8122-E8130
Publication
First Author: Wang H
Year: 2008
Journal: Blood
Title: IRF8 regulates B-cell lineage specification, commitment, and differentiation.
Volume: 112
Issue: 10
Pages: 4028-38
Publication
First Author: Schwab KR
Year: 2011
Journal: Mol Cell Biol
Title: Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus.
Volume: 31
Issue: 7
Pages: 1503-11
Publication
First Author: Chung EY
Year: 2012
Journal: J Clin Invest
Title: CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis.
Volume: 122
Issue: 6
Pages: 2257-66
Publication
First Author: Gruber TA
Year: 2010
Journal: Cancer Res
Title: Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.
Volume: 70
Issue: 19
Pages: 7411-20
Publication
First Author: Tusi BK
Year: 2015
Journal: FASEB J
Title: Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement.
Volume: 29
Issue: 4
Pages: 1505-15
Publication
First Author: Kuo YH
Year: 2008
Journal: Blood
Title: Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.
Volume: 111
Issue: 3
Pages: 1543-51
Publication
First Author: Alkhatib A
Year: 2012
Journal: J Exp Med
Title: FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination.
Volume: 209
Issue: 2
Pages: 395-406
Publication
First Author: Li S
Year: 2011
Journal: PLoS One
Title: Early growth response gene-2 (Egr-2) regulates the development of B and T cells.
Volume: 6
Issue: 4
Pages: e18498
Publication
First Author: Toda T
Year: 2009
Journal: Eur J Immunol
Title: The immature B-cell subpopulation with low RAG1 expression is increased in the autoimmune New Zealand Black mouse.
Volume: 39
Issue: 2
Pages: 600-11
Publication
First Author: Khoenkhoen S
Year: 2019
Journal: Immunol Cell Biol
Title: TACI expression and plasma cell differentiation are impaired in the absence of functional IκBNS.
Volume: 97
Issue: 5
Pages: 485-497
Publication
First Author: Venigalla RK
Year: 2013
Journal: EMBO J
Title: PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.
Volume: 32
Issue: 7
Pages: 1008-22
Publication
First Author: Balkhi MY
Year: 2012
Journal: Blood
Title: IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Volume: 119
Issue: 23
Pages: 5467-77
Publication
First Author: Wang S
Year: 2019
Journal: Genes Dev
Title: Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3.
Volume: 33
Issue: 15-16
Pages: 1048-1068
Publication
First Author: Maseda D
Year: 2012
Journal: J Immunol
Title: Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo.
Volume: 188
Issue: 3
Pages: 1036-48
Publication
First Author: Goetz CA
Year: 2005
Journal: J Immunol
Title: Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment.
Volume: 174
Issue: 12
Pages: 7753-63
Publication  
First Author: Yin M
Year: 2019
Journal: JCI Insight
Title: A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.
Volume: 4
Issue: 23
Publication
First Author: Ruer-Laventie J
Year: 2015
Journal: Immun Inflamm Dis
Title: Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation.
Volume: 3
Issue: 3
Pages: 265-79
Publication
First Author: Fedl AS
Year: 2024
Journal: Nat Immunol
Title: Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development.
Volume: 25
Issue: 9
Pages: 1663-1677
Publication
First Author: Meijne E
Year: 2001
Journal: Genes Chromosomes Cancer
Title: Analysis of loss of heterozygosity in lymphoma and leukaemia arising in F1 hybrid mice locates a common region of chromosome 4 loss.
Volume: 31
Issue: 4
Pages: 373-81
Publication
First Author: Chalepakis G
Year: 1995
Journal: Gene
Title: Identification of DNA recognition sequences for the Pax3 paired domain.
Volume: 162
Issue: 2
Pages: 267-70
Publication
First Author: Espinoza CR
Year: 2007
Journal: Mol Immunol
Title: Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes.
Volume: 44
Issue: 10
Pages: 2675-85