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Search results 701 to 800 out of 1171 for Pkd1

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:160629
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:4356532
Age: embryonic day 6.5
Image: 5A--embryo
Note: Expression is uniform.
Specimen Label: 5A--embryo
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-07-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6441879
Age: embryonic day 16.5
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 3
•
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•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-07-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6441879
Age: embryonic day 16.5
Image: 1D
Note: Expression shifted from epithelium to mesenchyme.
Specimen Label: 1D
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3539728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5142248
Age: postnatal adult
Image: 3b
Note: Expression is present in major coronary vessels.
Specimen Label: 3b
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3587528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5142248
Age: postnatal adult
Image: 3b
Specimen Label: 3b
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3513428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5142248
Age: postnatal adult
Image: 3c inset
Specimen Label: 3c inset
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1767424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:4356532
Age: embryonic day 16.5
Image: 6D
Note: Expression is confined to the prechondrocytes at the periphery.
Specimen Label: 6D
Detected: true
Specimen Num: 11
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1739219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4356532
Age: embryonic day 11.5
Specimen Label: Not shown
Detected: true
Specimen Num: 18
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•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752726
Pattern: Non-Uniform
Stage: TS26
Assay Id: MGI:4356532
Age: embryonic day 18.5
Image: 7E
Note: A particularly strong signal is seen in the dermis surrounding the developing hair follicles, especially the nasal region.
Specimen Label: 7E
Detected: true
Specimen Num: 23
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5142248
Age: embryonic day 11.5
Image: 3h
Specimen Label: 3h
Detected: true
Specimen Num: 18
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1668828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5142248
Age: postnatal adult
Image: 3b
Note: Expression is present in the atrial appendages.
Specimen Label: 3b
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500504
Specimen Label: MRC Harwell_1500504
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500517
Specimen Label: MRC Harwell_1500517
Detected: true
Specimen Num: 14
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6751610
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3273023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6751614
Age: embryonic day 15.5
Specimen Label: 7E +/-
Detected: true
Specimen Num: 1
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•
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•
GXD Expression
GXD Expression
     
Probe: MGI:6751610
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273023
Stage: TS23
Assay Id: MGI:6751614
Age: embryonic day 15.5
Specimen Label: 7E -/-
Detected: false
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4356187
Age: embryonic day 12.5
Image: 2--e12.5
Specimen Label: 2--e12.5
Detected: true
Specimen Num: 5
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884854
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944730
Age: embryonic day 15.5
Image: g00148 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00148 E15.5
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
Probe: MGI:4884854
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944730
Age: postnatal day 7
Image: g00148 P7
Note: Expression was region specific and scattered.
Specimen Label: g00148 P7
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:4884854
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944730
Age: postnatal day 42
Image: g00148 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00148 Adult
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500514
Specimen Label: MRC Harwell_1500514
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500504
Specimen Label: MRC Harwell_1500504
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2991528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4356532
Age: postnatal adult
Image: 5A--mother
Note: Expression is weak to absent along the mesometerium or inner uterine mucosa, immediately surrounding the embryo.
Specimen Label: 5A--mother
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500508
Specimen Label: MRC Harwell_1500508
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3609822
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3610137
Age: embryonic day 14.5
Specimen Label: None
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3609822
Assay Type: RNA in situ
Annotation Date: 2006-01-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3610137
Age: embryonic day 16.5
Specimen Label: None
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4356187
Age: embryonic day 12.5
Image: 2--e12.5
Specimen Label: 2--e12.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500513
Specimen Label: MRC Harwell_1500513
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500515
Specimen Label: MRC Harwell_1500515
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500516
Specimen Label: MRC Harwell_1500516
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:4356187
Age: embryonic day 12.5
Image: 2--e12.5
Note: Expression is present in the mesenchyme of the face.
Specimen Label: 2--e12.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693182
Age: postnatal adult
Image: MRC Harwell_1500508
Specimen Label: MRC Harwell_1500508
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1761820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4356187
Age: embryonic day 12.5
Image: 2--e12.5
Specimen Label: 2--e12.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2826628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5142248
Age: postnatal adult
Image: 2e
Specimen Label: 2e
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2772126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:4356187
Age: embryonic day 18.5
Image: 3E
Specimen Label: 3E
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2772125
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:4356532
Age: embryonic day 17.5
Image: 8A
Note: Expression is present in the cortical nephrogenic zone.
Specimen Label: 8A
Detected: true
Specimen Num: 25
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•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2772127
Pattern: Non-Uniform
Stage: TS27
Assay Id: MGI:4356532
Age: postnatal day 1.5-4.5
Image: 8B
Note: Stronger expression is present in the nephrogenic zone, with lesser signal present in more mature inner cortex.
Specimen Label: 8B
Detected: true
Specimen Num: 26
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•
GXD Expression
GXD Expression
Probe: MGI:3584981
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585856
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4356187
Age: postnatal adult
Image: 3G
Specimen Label: 3G
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5142248
Age: embryonic day 15.5
Image: 2h
Note: Expression is present in the maturing tubules of the nephron and collecting duct system.
Specimen Label: 2h
Detected: true
Specimen Num: 5
•
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•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5142248
Age: embryonic day 15.5
Image: 2i
Note: Expression is present in the maturing tubules of the nephron and collecting duct system.
Specimen Label: 2i
Detected: true
Specimen Num: 6
•
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•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2011-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5142248
Age: embryonic day 18.5
Image: 2j
Note: Expression is present in the maturing tubules of the nephron and collecting duct system.
Specimen Label: 2j
Detected: true
Specimen Num: 7
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6194208
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6194202
Age: embryonic day 14.5
Note: Expression was detected in primitive tubules.
Specimen Label: 5i
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:7488438
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7488443
Age: embryonic day 14.5
Image: 4C
Note: Expressed on the apical surfaces.
Specimen Label: 4C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7488438
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7488443
Age: embryonic day 14.5
Image: 4E
Note: Expressed on the apical surfaces, similar as in the wild-type.
Specimen Label: 4E
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4356183
Assay Type: RNA in situ
Annotation Date: 2009-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1625520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4356187
Age: embryonic day 12.5
Image: 2--e12.5
Note: Expression is present in the loops.
Specimen Label: 2--e12.5
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-07-16
Strength: Present
Sex: Male
Emaps: EMAPS:1657720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6441879
Age: embryonic day 12.0
Image: 1A
Note: Expression in Wolffian duct.
Specimen Label: 1A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2020-07-16
Strength: Strong
Sex: Male
Emaps: EMAPS:1657720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6441879
Age: embryonic day 12.0
Image: 1B
Note: Expression in Wolffian duct.
Specimen Label: 1B
Detected: true
Specimen Num: 2
•
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•
Publication
24854278 | J:226888
First Author: Inoue Y
Year: 2014
Journal: J Am Soc Nephrol
Title: Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model.
Volume: 25
Issue: 12
Pages: 2789-99
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Publication
20856870 | J:165121
First Author: Wodarczyk C
Year: 2010
Journal: PLoS One
Title: Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals.
Volume: 5
Issue: 9
Pages: e12719
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Publication
22795130 | J:187613
First Author: Fleig L
Year: 2012
Journal: Mol Cell
Title: Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins.
Volume: 47
Issue: 4
Pages: 558-69
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Publication
23001567 | J:191148
First Author: Foy RL
Year: 2012
Journal: Hum Mol Genet
Title: Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1.
Volume: 21
Issue: 26
Pages: 5456-71
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Publication
21518865 | J:172196
First Author: Talbot JJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Polycystin-1 regulates STAT activity by a dual mechanism.
Volume: 108
Issue: 19
Pages: 7985-90
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Publication
22025716 | J:180251
First Author: Olsan EE
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease.
Volume: 108
Issue: 44
Pages: 18067-72
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Publication
28341240 | J:329491
First Author: Wang E
Year: 2017
Journal: Kidney Int
Title: Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease.
Volume: 91
Issue: 2
Pages: 412-422
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Publication
18285569 | J:148449
First Author: Nauli SM
Year: 2008
Journal: Circulation
Title: Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1.
Volume: 117
Issue: 9
Pages: 1161-71
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Publication
38684863 | J:360436
First Author: Clerici S
Year: 2024
Journal: EMBO Mol Med
Title: Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Volume: 16
Issue: 6
Pages: 1379-1403
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Publication
37345660 | J:338527
 
First Author: Kleczko EK
Year: 2023
Journal: JCI Insight
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